JP2012511917A5 - - Google Patents

Info

Publication number

JP2012511917A5

JP2012511917A5 JP2011541165A JP2011541165A JP2012511917A5 JP 2012511917 A5 JP2012511917 A5 JP 2012511917A5 JP 2011541165 A JP2011541165 A JP 2011541165A JP 2011541165 A JP2011541165 A JP 2011541165A JP 2012511917 A5 JP2012511917 A5 JP 2012511917A5

Authority

JP

Japan

Prior art keywords

lymphocytes

amplification product

mammal

seq

methylation

Prior art date

2009-12-08

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 238000000034 method Methods 0.000 claims 19
• 210000001744 T-lymphocyte Anatomy 0.000 claims 17
• 108050005493 CD3 protein, epsilon/gamma/delta subunit Proteins 0.000 claims 13
• 102000017420 CD3 protein, epsilon/gamma/delta subunit Human genes 0.000 claims 12
• 241000124008 Mammalia Species 0.000 claims 10
• 230000003321 amplification Effects 0.000 claims 10
• 238000003199 nucleic acid amplification method Methods 0.000 claims 10
• 230000011987 methylation Effects 0.000 claims 8
• 238000007069 methylation reaction Methods 0.000 claims 8
• 239000000523 sample Substances 0.000 claims 6
• 238000004458 analytical method Methods 0.000 claims 5
• 238000012544 monitoring process Methods 0.000 claims 4
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• 206010052779 Transplant rejections Diseases 0.000 claims 2
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• 239000008280 blood Substances 0.000 claims 2
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• 239000000463 material Substances 0.000 claims 2
• 108090000623 proteins and genes Proteins 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 102100039162 Adenine nucleotide translocase lysine N-methyltransferase Human genes 0.000 claims 1
• LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 1
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• 101000856683 Homo sapiens C-X-C chemokine receptor type 6 Proteins 0.000 claims 1
• 101000884298 Homo sapiens CD226 antigen Proteins 0.000 claims 1
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• 101001055145 Homo sapiens Interleukin-2 receptor subunit beta Proteins 0.000 claims 1
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• 101000818605 Homo sapiens Zinc finger and BTB domain-containing protein 32 Proteins 0.000 claims 1
• 101000759545 Homo sapiens Zinc finger and BTB domain-containing protein 7B Proteins 0.000 claims 1
• 102100033016 Integrin beta-7 Human genes 0.000 claims 1
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• 102100022345 Serine/threonine-protein phosphatase 6 catalytic subunit Human genes 0.000 claims 1
• 102100024453 Signaling threshold-regulating transmembrane adapter 1 Human genes 0.000 claims 1
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• 102100033649 Tumor necrosis factor alpha-induced protein 8 Human genes 0.000 claims 1
• 102100031988 Tumor necrosis factor ligand superfamily member 6 Human genes 0.000 claims 1
• 102100024036 Tyrosine-protein kinase Lck Human genes 0.000 claims 1
• 102100040337 Ubiquitin-associated and SH3 domain-containing protein A Human genes 0.000 claims 1
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• 210000000601 blood cell Anatomy 0.000 claims 1
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• 108010072917 class-I restricted T cell-associated molecule Proteins 0.000 claims 1
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• 230000017858 demethylation Effects 0.000 claims 1
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