CA2747312C - Epigenetic markers for the identification of cd3/cd4+ or cd3/cd8+ t-lymphocytes - Google Patents
Epigenetic markers for the identification of cd3/cd4+ or cd3/cd8+ t-lymphocytes Download PDFInfo
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- CA2747312C CA2747312C CA2747312A CA2747312A CA2747312C CA 2747312 C CA2747312 C CA 2747312C CA 2747312 A CA2747312 A CA 2747312A CA 2747312 A CA2747312 A CA 2747312A CA 2747312 C CA2747312 C CA 2747312C
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- lymphocytes
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08021838.1 | 2008-12-16 | ||
| EP20080021838 EP2199411B1 (en) | 2008-12-16 | 2008-12-16 | Epigenetic markers for the identification of CD3 positive T-lymphocytes |
| PCT/EP2009/008764 WO2010069499A2 (en) | 2008-12-16 | 2009-12-08 | Epigenetic markers for the identification of blood sub-cells of type 1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2747312A1 CA2747312A1 (en) | 2010-06-24 |
| CA2747312C true CA2747312C (en) | 2018-11-06 |
Family
ID=40428037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2747312A Active CA2747312C (en) | 2008-12-16 | 2009-12-08 | Epigenetic markers for the identification of cd3/cd4+ or cd3/cd8+ t-lymphocytes |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120107810A1 (enExample) |
| EP (2) | EP2199411B1 (enExample) |
| JP (1) | JP2012511917A (enExample) |
| CA (1) | CA2747312C (enExample) |
| DK (2) | DK2199411T3 (enExample) |
| ES (1) | ES2606350T3 (enExample) |
| PL (1) | PL2376648T3 (enExample) |
| WO (1) | WO2010069499A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170233807A1 (en) | 2008-12-16 | 2017-08-17 | Epiontis Gmbh | Epigenetic Markers for the Identification of Blood Sub-cells of Type 1 |
| WO2012021867A2 (en) * | 2010-08-13 | 2012-02-16 | The Johns Hopkins University | A comprehensive methylome map of myeloid and lymphoid commitment from hematopoietic progenitors |
| CA2814150A1 (en) | 2010-10-08 | 2012-04-12 | Epiontis Gmbh | Method for determining cancer patient survival based on analyzing tumor-infiltrating overall t-lymphocytes |
| US20130296328A1 (en) * | 2011-01-20 | 2013-11-07 | Université Libre de Bruxelles | Epigenetic portraits of human breast cancers |
| EP2714933A4 (en) * | 2011-05-25 | 2014-12-31 | Univ Brown | METHODIZED METHOD FOR IDENTIFYING A CELL OR MIXING CELLS FOR THE PROGNOSIS AND DIAGNOSIS OF ILLNESSES AND FOR CELL HEALING THERAPIES |
| US20140178348A1 (en) | 2011-05-25 | 2014-06-26 | The Regents Of The University Of California | Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies |
| PL2788510T3 (pl) * | 2012-03-12 | 2017-07-31 | Epiontis Gmbh | Marker epigenetyczny do identyfikacji CD3CD4-pozytywnych limfocytów T |
| GB201221133D0 (en) * | 2012-11-23 | 2013-01-09 | Epiontis Gmbh | Epigenetic method for the identification of subpopulations of CD8 and T lympocytes, in particular CD8 alpha and beta T lymphocytes |
| CN107941681B (zh) | 2013-04-19 | 2021-07-30 | 艾皮恩蒂斯有限公司 | 鉴定生物样品中定量细胞组成的方法 |
| EP3360971A1 (en) * | 2017-02-09 | 2018-08-15 | Epiontis GmbH | Improved method for epigenetic immune cell counting |
| EP3382033B1 (en) * | 2017-03-30 | 2020-08-05 | Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen | Method for determining blood counts based on dna methylation |
| DE102017125019B4 (de) * | 2017-10-25 | 2019-10-17 | Epiontis Gmbh | PDCD1 als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere PD1+ Zellen |
| DE102018116353B4 (de) | 2018-07-05 | 2020-06-10 | Epiontis Gmbh | Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening |
| CN116949156B (zh) * | 2023-09-19 | 2023-12-08 | 美迪西普亚医药科技(上海)有限公司 | 一种基于核酸变体的通用型检测人t细胞的分析方法 |
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| JP2002171973A (ja) | 2000-12-07 | 2002-06-18 | Univ Tokyo | Ｄｎａメチル化パターンによる細胞の同定法 |
| AU2003285586A1 (en) | 2002-12-03 | 2004-06-23 | Medical Research Council | Regulatory t-cells |
| DK1826279T3 (da) | 2006-02-28 | 2011-09-05 | Charite Universitaetsmedizin | Detektering og kvalitetskontrol af regulatoriske t-celler vha. DNA-metyleringsanalyse af FoxP3--genet |
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| HK1163189A1 (zh) | 2012-09-07 |
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| PL2376648T3 (pl) | 2017-05-31 |
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