JP2012510461A - Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤 - Google Patents

Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤 Download PDF

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Publication number
JP2012510461A
JP2012510461A JP2011538092A JP2011538092A JP2012510461A JP 2012510461 A JP2012510461 A JP 2012510461A JP 2011538092 A JP2011538092 A JP 2011538092A JP 2011538092 A JP2011538092 A JP 2011538092A JP 2012510461 A JP2012510461 A JP 2012510461A
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Prior art keywords
seq
amino acid
antibody
nos
acid sequence
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JP2011538092A
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Japanese (ja)
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JP2012510461A5 (https=
Inventor
ルジユヌ，パスカル
ブリニヨー，パトリシア
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Sanofi SA
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Sanofi SA
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Publication of JP2012510461A publication Critical patent/JP2012510461A/ja
Publication of JP2012510461A5 publication Critical patent/JP2012510461A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011538092A 2008-11-28 2009-11-27 Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤 Withdrawn JP2012510461A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08291116.5 2008-11-28
EP08291116A EP2191840A1 (en) 2008-11-28 2008-11-28 Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
PCT/IB2009/055389 WO2010061357A1 (en) 2008-11-28 2009-11-27 Antitumor combinations containing antibodies recognizing specifically cd38 and melphalan

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015107404A Division JP6148696B2 (ja) 2008-11-28 2015-05-27 Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤

Publications (2)

Publication Number Publication Date
JP2012510461A true JP2012510461A (ja) 2012-05-10
JP2012510461A5 JP2012510461A5 (https=) 2012-11-22

Family

ID=40578382

Family Applications (3)

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JP2011538092A Withdrawn JP2012510461A (ja) 2008-11-28 2009-11-27 Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤
JP2015107404A Active JP6148696B2 (ja) 2008-11-28 2015-05-27 Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤
JP2017037860A Pending JP2017141233A (ja) 2008-11-28 2017-03-01 Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015107404A Active JP6148696B2 (ja) 2008-11-28 2015-05-27 Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤
JP2017037860A Pending JP2017141233A (ja) 2008-11-28 2017-03-01 Ｃｄ３８を特異的に認識する抗体およびメルファランを含有する抗腫瘍性組合せ剤

Country Status (33)

Country Link
US (1) US9259406B2 (https=)
EP (2) EP2191840A1 (https=)
JP (3) JP2012510461A (https=)
KR (1) KR101733252B1 (https=)
CN (1) CN102264385B (https=)
AR (1) AR074219A1 (https=)
AU (1) AU2009321249B2 (https=)
BR (1) BRPI0921864B1 (https=)
CA (1) CA2744990C (https=)
CL (1) CL2011001254A1 (https=)
CO (1) CO6440557A2 (https=)
CR (1) CR20110280A (https=)
EA (1) EA026867B1 (https=)
EC (1) ECSP11011062A (https=)
HN (1) HN2011001417A (https=)
IL (1) IL213116B (https=)
MA (1) MA32896B1 (https=)
ME (1) ME01136B (https=)
MX (1) MX342625B (https=)
MY (1) MY164577A (https=)
NI (1) NI201100105A (https=)
NZ (1) NZ593027A (https=)
PA (1) PA8850101A1 (https=)
PE (1) PE20120340A1 (https=)
PY (1) PY09043215A (https=)
SG (1) SG171820A1 (https=)
SV (1) SV2011003924A (https=)
TN (1) TN2011000232A1 (https=)
TW (1) TWI454260B (https=)
UA (1) UA107069C2 (https=)
UY (1) UY32263A (https=)
WO (1) WO2010061357A1 (https=)
ZA (1) ZA201103925B (https=)

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JP2015530399A (ja) * 2012-09-25 2015-10-15 モルフォシス エージー 組み合わせ及びその使用

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US10342869B2 (en) 2012-12-07 2019-07-09 The Regents Of The University Of California Compositions comprising anti-CD38 antibodies and lenalidomide
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CN107406506A (zh) 2014-12-04 2017-11-28 詹森生物科技公司 用于治疗急性髓系白血病的抗cd38抗体
EA201792546A1 (ru) 2015-05-20 2018-04-30 Янссен Байотек, Инк. Антитела к cd38 для лечения амилоидоза легких цепей и прочих cd38-положительных гематологических злокачественных опухолей
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Publication number Priority date Publication date Assignee Title
JP2015530399A (ja) * 2012-09-25 2015-10-15 モルフォシス エージー 組み合わせ及びその使用

Also Published As

Publication number Publication date
ECSP11011062A (es) 2011-07-29
KR101733252B1 (ko) 2017-05-08
ZA201103925B (en) 2012-09-26
EP2191840A1 (en) 2010-06-02
EA201100864A1 (ru) 2011-12-30
CL2011001254A1 (es) 2012-01-27
PY09043215A (es) 2013-11-01
WO2010061357A1 (en) 2010-06-03
SV2011003924A (es) 2011-10-07
TW201023855A (en) 2010-07-01
HK1164165A1 (en) 2012-09-21
ME01136B (me) 2013-03-20
MA32896B1 (fr) 2011-12-01
CO6440557A2 (es) 2012-05-15
CA2744990A1 (en) 2010-06-03
CR20110280A (es) 2011-09-20
IL213116A0 (en) 2011-07-31
JP2017141233A (ja) 2017-08-17
HN2011001417A (es) 2014-01-13
IL213116B (en) 2018-11-29
MX2011005670A (es) 2011-09-30
UA107069C2 (uk) 2014-11-25
EP2370094A1 (en) 2011-10-05
AR074219A1 (es) 2010-12-29
CN102264385B (zh) 2015-05-20
EA026867B1 (ru) 2017-05-31
US9259406B2 (en) 2016-02-16
MX342625B (es) 2016-10-06
NZ593027A (en) 2012-12-21
CA2744990C (en) 2019-05-07
JP2015205890A (ja) 2015-11-19
AU2009321249A1 (en) 2010-06-03
UY32263A (es) 2010-06-30
US20110274686A1 (en) 2011-11-10
PA8850101A1 (es) 2010-07-27
AU2009321249B2 (en) 2016-06-09
CN102264385A (zh) 2011-11-30
TWI454260B (zh) 2014-10-01
JP6148696B2 (ja) 2017-06-14
NI201100105A (es) 2011-12-13
SG171820A1 (en) 2011-07-28
BRPI0921864B1 (pt) 2022-11-16
PE20120340A1 (es) 2012-04-17
KR20110096550A (ko) 2011-08-30
MY164577A (en) 2018-01-15
BRPI0921864A2 (en) 2018-10-09
TN2011000232A1 (en) 2012-12-17

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