JP2012509321A5 - - Google Patents
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- Publication number
- JP2012509321A5 JP2012509321A5 JP2011537428A JP2011537428A JP2012509321A5 JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5 JP 2011537428 A JP2011537428 A JP 2011537428A JP 2011537428 A JP2011537428 A JP 2011537428A JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- compound
- ray powder
- disintegrant
- powder diffraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19988808P | 2008-11-21 | 2008-11-21 | |
| US61/199,888 | 2008-11-21 | ||
| US21039809P | 2009-03-17 | 2009-03-17 | |
| US61/210,398 | 2009-03-17 | ||
| PCT/US2009/006235 WO2010059239A2 (en) | 2008-11-21 | 2009-11-20 | Lactate salt of 4-(6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide and pharmaceutical compositions thereof for the treatment of cancer and other diseases or disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014193355A Division JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509321A JP2012509321A (ja) | 2012-04-19 |
| JP2012509321A5 true JP2012509321A5 (cg-RX-API-DMAC7.html) | 2012-12-27 |
Family
ID=41508688
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537428A Pending JP2012509321A (ja) | 2008-11-21 | 2009-11-20 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
| JP2014193355A Pending JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014193355A Pending JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100273808A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2370417A2 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2012509321A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010059239A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524505A (zh) | 2009-03-13 | 2018-09-14 | 安吉奥斯医药品有限公司 | 用于细胞增殖相关病症的方法和组合物 |
| PT2448582T (pt) | 2009-06-29 | 2017-07-10 | Agios Pharmaceuticals Inc | Compostos e composições terapêuticas |
| ES2594402T3 (es) | 2009-10-21 | 2016-12-20 | Agios Pharmaceuticals, Inc. | Métodos y composiciones para trastornos relacionados con la proliferación celular |
| SG194697A1 (en) | 2011-05-03 | 2013-12-30 | Agios Pharmaceuticals Inc | Pyruvate kinase activators for use in therapy |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| NZ706999A (en) | 2012-10-15 | 2018-12-21 | Agios Pharmaceuticals Inc | Inhibitors of mutant isocitrate dehydrogenase and therapeutical uses thereof |
| JP2014129238A (ja) * | 2012-12-28 | 2014-07-10 | Lion Corp | エトドラク含有固形製剤 |
| CN103058959B (zh) * | 2013-01-04 | 2014-09-10 | 华东理工大学 | 一种n-(2-(4-甲基哌嗪-1-基)-5-甲酰苯基)酰胺类化合物及其应用 |
| KR20140096571A (ko) * | 2013-01-28 | 2014-08-06 | 한미약품 주식회사 | 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법 |
| US9579324B2 (en) | 2013-07-11 | 2017-02-28 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| US10376510B2 (en) | 2013-07-11 | 2019-08-13 | Agios Pharmaceuticals, Inc. | 2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of cancer |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| WO2015003360A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| UA122962C2 (uk) * | 2014-03-14 | 2021-01-27 | Аджіос Фармасьютикалз, Інк. | Спосіб лікування поширених солідних пухлин, які характеризуються наявністю мутантного алеля idh1 |
| CN112159391A (zh) * | 2014-03-14 | 2021-01-01 | 阿吉奥斯制药公司 | 治疗活性化合物的药物组合物 |
| SI3307271T1 (sl) | 2015-06-11 | 2023-11-30 | Agios Pharmaceuticals, Inc. | Postopki za uporabo aktivatorjev piruvat kinaze |
| EP3362065B1 (en) | 2015-10-15 | 2024-04-03 | Les Laboratoires Servier | Combination therapy comprising ivosidenib, cytarabine and daunorubicin or idarubicin for treating acute myelogenous leukemia |
| HUE057263T2 (hu) | 2015-10-15 | 2022-04-28 | Servier Lab | Kombinációs terápia rosszindulató betegségek kezelésére |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| WO2022078927A1 (en) | 2020-10-13 | 2022-04-21 | Boehringer Ingelheim International Gmbh | Process of reworking |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3091221B2 (ja) | 1990-05-25 | 2000-09-25 | ザ・オーストラリアン・ナショナル・ユニバーシティ | 立方晶窒化ホウ素の研磨コンパクトおよびその製造方法 |
| US5101609A (en) | 1991-07-15 | 1992-04-07 | Eastman Kodak Company | Cigarette package inspection indexing wheel |
| JP2753911B2 (ja) * | 1991-12-06 | 1998-05-20 | キッセイ薬品工業株式会社 | Ｎ−ｔｅｒｔ−ブチル−１−メチル−３，３−ジフェニルプロピルアミン塩酸塩の結晶多形およびその製造方法 |
| JPH05230044A (ja) * | 1992-02-21 | 1993-09-07 | Hoechst Japan Ltd | ピレタニドの新規な結晶多形 |
| JP3532988B2 (ja) * | 1995-02-22 | 2004-05-31 | アベンティス ファーマ株式会社 | ピレタニドの新規な結晶多形およびその製造方法 |
| KR100622323B1 (ko) * | 1996-10-01 | 2006-11-30 | 교와 핫꼬 고교 가부시끼가이샤 | 질소-함유헤테로고리화합물 |
| JP3011904B2 (ja) * | 1997-06-10 | 2000-02-21 | 明久 井上 | 金属ガラスの製造方法および装置 |
| WO1999051582A1 (en) * | 1998-03-31 | 1999-10-14 | Kyowa Hakko Kogyo Co., Ltd. | Nitrogenous heterocyclic compounds |
| WO2002016361A2 (en) * | 2000-08-18 | 2002-02-28 | Cor Therapeutics, Inc. | Nitrogenous heterocyclic compounds |
| JP5073147B2 (ja) | 2000-08-18 | 2012-11-14 | ミレニアム ファーマシューティカルズ インク． | キナーゼインヒビターとしてのキナゾリン誘導体 |
| DE60143204D1 (de) * | 2000-08-18 | 2010-11-18 | Kyowa Hakko Kirin Co Ltd | N-aryl-ä4-Ä7-(alkoxy)Chinazolin-4-ylÜPiperazinylüCarboxamid-Verbindungen als PDGF-Rezeptoren Hemmer |
| ATE502928T1 (de) * | 2000-11-01 | 2011-04-15 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
| US20040259881A1 (en) * | 2001-02-02 | 2004-12-23 | Anjali Pandey | Nitrogenous heterocyclic compounds |
| WO2002072578A2 (en) * | 2001-03-08 | 2002-09-19 | Millennium Pharmaceuticals | (homo) piperazine substituted quinolines for inhibiting the phosphorylation of kinases |
| US7058169B2 (en) * | 2003-08-27 | 2006-06-06 | D.B. Zwirn Finance, Llc | Skill based chat function in a communication system |
| US7456189B2 (en) * | 2003-09-30 | 2008-11-25 | Boehringer Ingelheim International Gmbh | Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation |
| MXPA06004194A (es) * | 2003-11-07 | 2006-06-28 | Chiron Corp | Inhibicion de fgfr3 y tratamiento de mieloma multiple. |
| US20060063735A1 (en) * | 2004-09-17 | 2006-03-23 | Supergen, Inc. | Salts of 5-azacytidine |
| JP2008519055A (ja) * | 2004-11-08 | 2008-06-05 | シャイア エルエルシー | ミルタザピンと興奮剤複合物の併用投与の相乗効果 |
| JP5507049B2 (ja) * | 2004-12-30 | 2014-05-28 | アステックス、セラピューティックス、リミテッド | 医薬品 |
| EP1843769A1 (en) * | 2005-01-07 | 2007-10-17 | Pfizer Products Incorporated | Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene |
| JP2009502804A (ja) * | 2005-07-20 | 2009-01-29 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | ４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの新規な結晶形 |
| DE102005042784A1 (de) | 2005-07-26 | 2007-02-01 | Bosch Rexroth Aktiengesellschaft | Ventilanordnung und Kühlvorrichtung |
-
2009
- 2009-11-20 WO PCT/US2009/006235 patent/WO2010059239A2/en not_active Ceased
- 2009-11-20 EP EP09771435A patent/EP2370417A2/en not_active Withdrawn
- 2009-11-20 JP JP2011537428A patent/JP2012509321A/ja active Pending
- 2009-11-20 US US12/622,617 patent/US20100273808A1/en not_active Abandoned
-
2014
- 2014-09-24 JP JP2014193355A patent/JP2015017116A/ja active Pending
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