JP2012508865A5 - - Google Patents
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- JP2012508865A5 JP2012508865A5 JP2011535211A JP2011535211A JP2012508865A5 JP 2012508865 A5 JP2012508865 A5 JP 2012508865A5 JP 2011535211 A JP2011535211 A JP 2011535211A JP 2011535211 A JP2011535211 A JP 2011535211A JP 2012508865 A5 JP2012508865 A5 JP 2012508865A5
- Authority
- JP
- Japan
- Prior art keywords
- antigens
- listed
- pattern
- group
- reactivity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 82
- 102000036639 antigens Human genes 0.000 claims 82
- 108091007433 antigens Proteins 0.000 claims 82
- 230000009257 reactivity Effects 0.000 claims 18
- 239000000523 sample Substances 0.000 claims 17
- 238000000034 method Methods 0.000 claims 16
- 201000006417 multiple sclerosis Diseases 0.000 claims 14
- 208000007118 chronic progressive multiple sclerosis Diseases 0.000 claims 13
- 208000007400 Relapsing-Remitting Multiple Sclerosis Diseases 0.000 claims 9
- 230000003902 lesion Effects 0.000 claims 8
- 201000008628 secondary progressive multiple sclerosis Diseases 0.000 claims 7
- 206010063401 primary progressive multiple sclerosis Diseases 0.000 claims 6
- 230000001575 pathological effect Effects 0.000 claims 2
- 238000003909 pattern recognition Methods 0.000 claims 2
- 239000013068 control sample Substances 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11364508P | 2008-11-12 | 2008-11-12 | |
| US61/113,645 | 2008-11-12 | ||
| PCT/IL2009/001066 WO2010055510A2 (en) | 2008-11-12 | 2009-11-12 | Diagnosis of multiple sclerosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012508865A JP2012508865A (ja) | 2012-04-12 |
| JP2012508865A5 true JP2012508865A5 (enExample) | 2012-12-27 |
Family
ID=42170484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011535211A Pending JP2012508865A (ja) | 2008-11-12 | 2009-11-12 | 多発性硬化症の診断 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9267945B2 (enExample) |
| EP (1) | EP2353004B1 (enExample) |
| JP (1) | JP2012508865A (enExample) |
| CN (1) | CN102388307B (enExample) |
| AU (1) | AU2009315230A1 (enExample) |
| CA (1) | CA2743590A1 (enExample) |
| WO (1) | WO2010055510A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140105980A1 (en) | 2012-10-11 | 2014-04-17 | Uti Limited Partnership | Methods and compositions for treating multiple sclerosis and related disorders |
| US20190263888A1 (en) | 2010-10-19 | 2019-08-29 | Op-T Llc | Therapeutic peptides and methods for treating autoimmune related disease |
| ES2677844T3 (es) | 2010-10-19 | 2018-08-07 | The Regents Of The University Of Colorado, A Body Corporate | Péptidos para modular la actividad de linfocitos T y usos de los mismos |
| US9511151B2 (en) | 2010-11-12 | 2016-12-06 | Uti Limited Partnership | Compositions and methods for the prevention and treatment of cancer |
| US10988516B2 (en) | 2012-03-26 | 2021-04-27 | Uti Limited Partnership | Methods and compositions for treating inflammation |
| US8652999B1 (en) | 2012-07-24 | 2014-02-18 | Dow Agrosciences, Llc. | Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and a sulfonylaminocarbonyltriazolinone |
| US9603948B2 (en) | 2012-10-11 | 2017-03-28 | Uti Limited Partnership | Methods and compositions for treating multiple sclerosis and related disorders |
| GB201300684D0 (en) | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
| PL3065771T3 (pl) | 2013-11-04 | 2019-09-30 | Uti Limited Partnership | Sposoby i kompozycje dla długotrwałej immunoterapii |
| JP6550388B2 (ja) * | 2013-12-12 | 2019-07-24 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． | 神経変性疾患の治療 |
| WO2015101987A1 (en) | 2013-12-31 | 2015-07-09 | Yeda Research And Development Co. Ltd. | Methods for assaying immunological competence |
| US10545144B2 (en) | 2013-12-31 | 2020-01-28 | Yeda Research And Development Co., Ltd. | Diagnosis of systemic lupus erythematosus using oligonucleotides antigens |
| US20170108514A1 (en) * | 2014-03-23 | 2017-04-20 | The Regents Of The University Of Colorado, A Body Corporate | Diagnosis of multiple sclerosis in human and animal subjects |
| EP2927687A1 (en) * | 2014-03-31 | 2015-10-07 | Ecole Polytechnique Federale de Lausanne (EPFL) | Agents useful in diagnostic and therapy of beta-amyloid aggregation related disorders and screening methods |
| WO2015172008A1 (en) * | 2014-05-09 | 2015-11-12 | Multiple Sclerosis Research Center Of New York | Transglutaminadase 6 as a biomarker for multiple sclerosis |
| EP3250923A4 (en) | 2015-01-30 | 2018-06-20 | The Regents of The University of California | N-acetyl glucosamine as a biomarker of ms disease course |
| EP3265814B1 (en) | 2015-03-01 | 2020-11-18 | Immunarray Ltd. | Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens |
| KR20250140122A (ko) | 2015-05-06 | 2025-09-24 | 유티아이 리미티드 파트너쉽 | 지속 치료를 위한 나노입자 조성물 |
| CN107043413A (zh) * | 2016-02-05 | 2017-08-15 | 华中农业大学 | 一种肺结核相关的尿液生物标志蛋白及其应用 |
| WO2018048884A1 (en) * | 2016-09-09 | 2018-03-15 | Mayo Foundation For Medical Education And Research | Methods and materials for identifying and treating autoimmune gfap astrocytopathy |
| CA3042615A1 (en) | 2016-11-09 | 2018-05-17 | Uti Limited Partnership | Recombinant pmhc class ii molecules |
| CA3059016A1 (en) | 2017-04-07 | 2018-10-11 | Uti Limited Partnership | Assay to measure the potency of receptor-ligand interactions in nanomedicines |
| AU2018374569B2 (en) | 2017-11-29 | 2024-10-17 | Uti Limited Partnership | Methods of treating autoimmune disease |
| US11793854B2 (en) | 2019-03-21 | 2023-10-24 | Op-T Llc | Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction |
| US12048734B2 (en) | 2020-04-17 | 2024-07-30 | Op-T Llc | Bioactive peptides and methods of use thereof |
| CN114689865A (zh) * | 2020-12-30 | 2022-07-01 | 广州市微米生物科技有限公司 | 视神经脊髓炎抗体检测试剂 |
| CN113336862B (zh) * | 2021-07-05 | 2022-03-01 | 广东省科学院动物研究所 | 一种抗多发性硬化的重组蛋白及其制备方法和用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL137460A0 (en) | 2000-07-24 | 2001-07-24 | Yeda Res & Dev | Identifying antigen clusters for monitoring a global state of an immune system |
| KR100951409B1 (ko) | 2001-01-09 | 2010-04-07 | 베일러 리서치 인스티튜트 | 수지상 세포로의 단핵세포 분화를 억제하는 조성물 및 이를 포함하는 키트 |
| WO2002084249A2 (en) | 2001-04-10 | 2002-10-24 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic and diagnostic uses of antibody specificity profiles |
| US20030092089A1 (en) | 2001-11-14 | 2003-05-15 | Moscarello Mario Anthony | Method for diagnosing multiple sclerosis and an assay therefore |
| IL148401A0 (en) | 2002-02-26 | 2002-09-12 | Hadasit Med Res Service | Hsp70-derived peptides and uses thereof in the diagnosis and treatment of autoimmune diseases |
| US20050009096A1 (en) | 2002-10-11 | 2005-01-13 | The Regents Of The University Of California | Method for diagnosis and prognosis of multiple sclerosis |
| US20050260770A1 (en) | 2004-04-01 | 2005-11-24 | Cohen Irun R | Antigen array and diagnostic uses thereof |
| KR20070046096A (ko) | 2004-07-01 | 2007-05-02 | 코벤하븐스 유니벌스테 | 다발성 경화증 치료 및 예방을 위한 방법 |
| US20080194711A1 (en) | 2005-01-19 | 2008-08-14 | Frauke Zipp-Nitsch | Cx3Cr1 As A Marker Which Correlates With Both Disease And Disease Activity In Multiple Sclerosis Patients |
| US7572592B2 (en) * | 2005-01-31 | 2009-08-11 | Glycominds Ltd | Method for diagnosing multiple sclerosis |
| AU2006214473A1 (en) | 2005-02-14 | 2006-08-24 | Wyeth | Interleukin-17F antibodies and other IL-17F signaling antagonists and uses therefor |
| WO2006116155A2 (en) * | 2005-04-21 | 2006-11-02 | The Regents Of The University Of California | A method for diagnosis and prognosis of multiple sclerosis subtypes |
| WO2007014001A2 (en) * | 2005-07-21 | 2007-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplex determination of lipid specific binding moieties |
| WO2007056332A2 (en) | 2005-11-07 | 2007-05-18 | Vanderbilt University | Molecular diagnosis of autoimmune diseases |
| JP2009538416A (ja) * | 2006-05-26 | 2009-11-05 | フェノメノーム ディスカバリーズ インク | 多発性硬化症を診断するための生物マーカー、及びその方法 |
| EP2145182A2 (en) * | 2007-04-12 | 2010-01-20 | Apitope International NV | Biomarkers for multiple sclerosis |
-
2009
- 2009-11-12 JP JP2011535211A patent/JP2012508865A/ja active Pending
- 2009-11-12 CA CA2743590A patent/CA2743590A1/en not_active Abandoned
- 2009-11-12 US US13/128,862 patent/US9267945B2/en not_active Expired - Fee Related
- 2009-11-12 CN CN200980154256.5A patent/CN102388307B/zh not_active Expired - Fee Related
- 2009-11-12 EP EP09825840.3A patent/EP2353004B1/en not_active Not-in-force
- 2009-11-12 AU AU2009315230A patent/AU2009315230A1/en not_active Abandoned
- 2009-11-12 WO PCT/IL2009/001066 patent/WO2010055510A2/en not_active Ceased
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