JP2012508865A5 - - Google Patents
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- JP2012508865A5 JP2012508865A5 JP2011535211A JP2011535211A JP2012508865A5 JP 2012508865 A5 JP2012508865 A5 JP 2012508865A5 JP 2011535211 A JP2011535211 A JP 2011535211A JP 2011535211 A JP2011535211 A JP 2011535211A JP 2012508865 A5 JP2012508865 A5 JP 2012508865A5
- Authority
- JP
- Japan
- Prior art keywords
- antigens
- listed
- pattern
- group
- reactivity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 82
- 102000036639 antigens Human genes 0.000 claims 82
- 108091007433 antigens Proteins 0.000 claims 82
- 230000009257 reactivity Effects 0.000 claims 18
- 239000000523 sample Substances 0.000 claims 17
- 238000000034 method Methods 0.000 claims 16
- 201000006417 multiple sclerosis Diseases 0.000 claims 14
- 208000007118 chronic progressive multiple sclerosis Diseases 0.000 claims 13
- 208000007400 Relapsing-Remitting Multiple Sclerosis Diseases 0.000 claims 9
- 230000003902 lesion Effects 0.000 claims 8
- 201000008628 secondary progressive multiple sclerosis Diseases 0.000 claims 7
- 206010063401 primary progressive multiple sclerosis Diseases 0.000 claims 6
- 230000001575 pathological effect Effects 0.000 claims 2
- 238000003909 pattern recognition Methods 0.000 claims 2
- 239000013068 control sample Substances 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11364508P | 2008-11-12 | 2008-11-12 | |
| US61/113,645 | 2008-11-12 | ||
| PCT/IL2009/001066 WO2010055510A2 (en) | 2008-11-12 | 2009-11-12 | Diagnosis of multiple sclerosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012508865A JP2012508865A (ja) | 2012-04-12 |
| JP2012508865A5 true JP2012508865A5 (enExample) | 2012-12-27 |
Family
ID=42170484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011535211A Pending JP2012508865A (ja) | 2008-11-12 | 2009-11-12 | 多発性硬化症の診断 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9267945B2 (enExample) |
| EP (1) | EP2353004B1 (enExample) |
| JP (1) | JP2012508865A (enExample) |
| CN (1) | CN102388307B (enExample) |
| AU (1) | AU2009315230A1 (enExample) |
| CA (1) | CA2743590A1 (enExample) |
| WO (1) | WO2010055510A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140105980A1 (en) | 2012-10-11 | 2014-04-17 | Uti Limited Partnership | Methods and compositions for treating multiple sclerosis and related disorders |
| EP2629797B1 (en) | 2010-10-19 | 2018-05-23 | The Regents of the University of Colorado, A Body Corporate | Peptides for modulating t-cell activity and uses thereof |
| US20190263888A1 (en) | 2010-10-19 | 2019-08-29 | Op-T Llc | Therapeutic peptides and methods for treating autoimmune related disease |
| US9511151B2 (en) | 2010-11-12 | 2016-12-06 | Uti Limited Partnership | Compositions and methods for the prevention and treatment of cancer |
| US10988516B2 (en) | 2012-03-26 | 2021-04-27 | Uti Limited Partnership | Methods and compositions for treating inflammation |
| US8652999B1 (en) | 2012-07-24 | 2014-02-18 | Dow Agrosciences, Llc. | Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and a sulfonylaminocarbonyltriazolinone |
| US9603948B2 (en) | 2012-10-11 | 2017-03-28 | Uti Limited Partnership | Methods and compositions for treating multiple sclerosis and related disorders |
| GB201300684D0 (en) | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
| EP3065771B1 (en) | 2013-11-04 | 2019-03-20 | UTI Limited Partnership | Methods and compositions for sustained immunotherapy |
| CN106030302B (zh) * | 2013-12-12 | 2019-09-24 | 布里格姆妇女医院 | 治疗神经变性疾病 |
| US20160320384A1 (en) | 2013-12-31 | 2016-11-03 | Yeda Research And Development Co. Ltd. | Methods for assaying immunological competence |
| EP3090064B1 (en) | 2013-12-31 | 2019-11-13 | Yeda Research and Development Co. Ltd. | Diagnosis of systemic lupus erythematosus using oligonucleotides antigens |
| US20170108514A1 (en) * | 2014-03-23 | 2017-04-20 | The Regents Of The University Of Colorado, A Body Corporate | Diagnosis of multiple sclerosis in human and animal subjects |
| EP2927687A1 (en) * | 2014-03-31 | 2015-10-07 | Ecole Polytechnique Federale de Lausanne (EPFL) | Agents useful in diagnostic and therapy of beta-amyloid aggregation related disorders and screening methods |
| WO2015172008A1 (en) * | 2014-05-09 | 2015-11-12 | Multiple Sclerosis Research Center Of New York | Transglutaminadase 6 as a biomarker for multiple sclerosis |
| EP3250923A4 (en) | 2015-01-30 | 2018-06-20 | The Regents of The University of California | N-acetyl glucosamine as a biomarker of ms disease course |
| WO2016139659A1 (en) | 2015-03-01 | 2016-09-09 | Immunarray Ltd. | Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens |
| BR112017023853A2 (pt) | 2015-05-06 | 2018-07-17 | Uti Limited Partnership | composições de nanopartícula para terapia sustentada. |
| CN107043413A (zh) * | 2016-02-05 | 2017-08-15 | 华中农业大学 | 一种肺结核相关的尿液生物标志蛋白及其应用 |
| US11402379B2 (en) * | 2016-09-09 | 2022-08-02 | Mayo Foundation For Medical Education And Research | Methods and materials for identifying and treating autoimmune GFAP astrocytopathy |
| ES3035837T3 (en) | 2016-11-09 | 2025-09-10 | Uti Lp | Recombinant pmhc class ii molecules |
| EP3607058A4 (en) | 2017-04-07 | 2020-12-16 | UTI Limited Partnership | ASSAY FOR MEASURING THE POWER OF LIGAND-RECEPTOR INTERACTIONS IN NANOMEDUCINES |
| US12397038B2 (en) | 2017-11-29 | 2025-08-26 | Uti Limited Partnership | Ubiquitous antigens for treatment of autoimmune or inflammatory diseases |
| US11793854B2 (en) | 2019-03-21 | 2023-10-24 | Op-T Llc | Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction |
| EP4135742A2 (en) | 2020-04-17 | 2023-02-22 | Op-T Llc | Bioactive peptides and methods of use thereof |
| CN114689865A (zh) * | 2020-12-30 | 2022-07-01 | 广州市微米生物科技有限公司 | 视神经脊髓炎抗体检测试剂 |
| CN113336862B (zh) * | 2021-07-05 | 2022-03-01 | 广东省科学院动物研究所 | 一种抗多发性硬化的重组蛋白及其制备方法和用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL137460A0 (en) * | 2000-07-24 | 2001-07-24 | Yeda Res & Dev | Identifying antigen clusters for monitoring a global state of an immune system |
| WO2002067760A2 (en) * | 2001-01-09 | 2002-09-06 | Baylor Research Institute | Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays |
| EP1386155A4 (en) | 2001-04-10 | 2006-05-10 | Univ Leland Stanford Junior | THERAPEUTIC AND DIAGNOSTIC USE OF ANTIBODY SPECIFICITY PROFILES |
| US20030092089A1 (en) | 2001-11-14 | 2003-05-15 | Moscarello Mario Anthony | Method for diagnosing multiple sclerosis and an assay therefore |
| IL148401A0 (en) * | 2002-02-26 | 2002-09-12 | Hadasit Med Res Service | Hsp70-derived peptides and uses thereof in the diagnosis and treatment of autoimmune diseases |
| WO2004034031A2 (en) * | 2002-10-11 | 2004-04-22 | The Regents Of The University Of California | A method for diagnosis and prognosis of multiple sclerosis |
| US20050260770A1 (en) | 2004-04-01 | 2005-11-24 | Cohen Irun R | Antigen array and diagnostic uses thereof |
| US20080193440A1 (en) | 2004-07-01 | 2008-08-14 | Kobenhavns Universitet | Method For Multiple Sclerosis Treatment and Prophylaxis By Treatment of Leptospira Infection |
| JP2008526245A (ja) | 2005-01-19 | 2008-07-24 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | 多発性硬化症の患者における疾患および疾患活性の両方と相関するマーカーとしてのｃｘ３ｃｒ１ |
| US7572592B2 (en) * | 2005-01-31 | 2009-08-11 | Glycominds Ltd | Method for diagnosing multiple sclerosis |
| PE20061391A1 (es) | 2005-02-14 | 2007-01-09 | Wyeth Corp | Anticuerpos para interleucina-17f y otros antagonistas de la senalizacion de il-17f |
| WO2006116155A2 (en) * | 2005-04-21 | 2006-11-02 | The Regents Of The University Of California | A method for diagnosis and prognosis of multiple sclerosis subtypes |
| WO2007014001A2 (en) * | 2005-07-21 | 2007-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplex determination of lipid specific binding moieties |
| WO2007056332A2 (en) | 2005-11-07 | 2007-05-18 | Vanderbilt University | Molecular diagnosis of autoimmune diseases |
| JP2009538416A (ja) * | 2006-05-26 | 2009-11-05 | フェノメノーム ディスカバリーズ インク | 多発性硬化症を診断するための生物マーカー、及びその方法 |
| EP2145182A2 (en) | 2007-04-12 | 2010-01-20 | Apitope International NV | Biomarkers for multiple sclerosis |
-
2009
- 2009-11-12 CA CA2743590A patent/CA2743590A1/en not_active Abandoned
- 2009-11-12 CN CN200980154256.5A patent/CN102388307B/zh not_active Expired - Fee Related
- 2009-11-12 US US13/128,862 patent/US9267945B2/en not_active Expired - Fee Related
- 2009-11-12 EP EP09825840.3A patent/EP2353004B1/en not_active Not-in-force
- 2009-11-12 AU AU2009315230A patent/AU2009315230A1/en not_active Abandoned
- 2009-11-12 WO PCT/IL2009/001066 patent/WO2010055510A2/en not_active Ceased
- 2009-11-12 JP JP2011535211A patent/JP2012508865A/ja active Pending
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