JP2009522578A5 - - Google Patents
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- JP2009522578A5 JP2009522578A5 JP2008549563A JP2008549563A JP2009522578A5 JP 2009522578 A5 JP2009522578 A5 JP 2009522578A5 JP 2008549563 A JP2008549563 A JP 2008549563A JP 2008549563 A JP2008549563 A JP 2008549563A JP 2009522578 A5 JP2009522578 A5 JP 2009522578A5
- Authority
- JP
- Japan
- Prior art keywords
- patient
- marker
- determining
- markers
- ovarian cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75613106P | 2006-01-04 | 2006-01-04 | |
| US60/756,131 | 2006-01-04 | ||
| PCT/US2007/000216 WO2007081768A2 (en) | 2006-01-04 | 2007-01-04 | Use of he4 and other biochemical markers for assessment of ovarian cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012226640A Division JP5711196B2 (ja) | 2006-01-04 | 2012-10-12 | 卵巣癌を判定するためのhe4及び他の生化学マーカーの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009522578A JP2009522578A (ja) | 2009-06-11 |
| JP2009522578A5 true JP2009522578A5 (enExample) | 2010-02-25 |
| JP5221381B2 JP5221381B2 (ja) | 2013-06-26 |
Family
ID=38256906
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549562A Active JP5164855B2 (ja) | 2006-01-04 | 2007-01-04 | 子宮内膜または子宮癌を評価するためのhe4及びそのほかの生化学的マーカーの使用 |
| JP2008549563A Active JP5221381B2 (ja) | 2006-01-04 | 2007-01-04 | 卵巣癌を判定するためのhe4及び他の生化学マーカーの使用 |
| JP2012226640A Active JP5711196B2 (ja) | 2006-01-04 | 2012-10-12 | 卵巣癌を判定するためのhe4及び他の生化学マーカーの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549562A Active JP5164855B2 (ja) | 2006-01-04 | 2007-01-04 | 子宮内膜または子宮癌を評価するためのhe4及びそのほかの生化学的マーカーの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012226640A Active JP5711196B2 (ja) | 2006-01-04 | 2012-10-12 | 卵巣癌を判定するためのhe4及び他の生化学マーカーの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (8) | US20080020473A1 (enExample) |
| EP (6) | EP2982761B1 (enExample) |
| JP (3) | JP5164855B2 (enExample) |
| CN (3) | CN101460630B (enExample) |
| ES (2) | ES2650244T3 (enExample) |
| PL (1) | PL2982761T3 (enExample) |
| WO (2) | WO2007081768A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5731400A (en) * | 1999-06-09 | 2000-12-28 | Moltech Corporation | Methods of preparing electrochemical cells |
| US7270960B2 (en) | 2001-08-29 | 2007-09-18 | Pacific Northwest Research Institute | Diagnosis of ovarian carcinomas |
| EP1877795A4 (en) * | 2005-05-02 | 2010-04-28 | Brigham & Womens Hospital | DIAGNOSTIC PROFILE MANUFACTURE OF SERUM ANTIBODIES |
| EP2982761B1 (en) * | 2006-01-04 | 2017-10-04 | Fujirebio America, Inc. | Use of he4 and other biochemical markers for assessment of endometrial and uterine cancers |
| BRPI0707249A2 (pt) * | 2006-01-27 | 2011-04-26 | Tripath Imaging Inc | métodos para identificar pacientes com maior probabilidade de terem cáncer de ovário e composições para os mesmo |
| WO2008049239A1 (en) | 2006-10-27 | 2008-05-02 | Mount Sinai Hospital | Endometrial biomarkers |
| CA2679696A1 (en) * | 2007-03-09 | 2008-09-18 | Tripath Imaging, Inc. | He4 monoclonal antibodies and methods for their use |
| JP5144742B2 (ja) * | 2007-03-29 | 2013-02-13 | フジレビオ ダイアグノスティックス インコーポレイテッド | 乳がんの評価のためのhe4の使用 |
| CN101377502A (zh) * | 2007-08-31 | 2009-03-04 | 北京科美东雅生物技术有限公司 | 肿瘤相关抗原72-4化学发光免疫分析测定试剂盒及其制备方法 |
| WO2009099561A2 (en) * | 2008-01-31 | 2009-08-13 | The Brigham And Womens' Hospital, Inc. | Urinary ca125 peptides as biomarkers of ovarian cancer |
| WO2009145815A2 (en) * | 2008-04-01 | 2009-12-03 | The Brigham And Women's Hospital, Inc. | Biomarkers of ovarian cancer |
| WO2012027631A2 (en) * | 2010-08-26 | 2012-03-01 | University Of Washington Through Its Center For Commercialization | Methods for detecting anti-he4 antibodies and methods of diagnosis and/or prognosis of conditions associated with he4-expressing cells |
| ES2834617T3 (es) | 2011-02-17 | 2021-06-18 | Fujirebio Diagnostics Inc | Composiciones y métodos de uso para la determinación de HE4a |
| CA2828119A1 (en) * | 2011-02-24 | 2012-08-30 | Vermillion, Inc. | Biomarker panels, diagnostic methods and test kits for ovarian cancer |
| CN102735840B (zh) * | 2011-04-13 | 2014-06-04 | 中国医学科学院肿瘤研究所 | 用于诊断或筛查卵巢癌的试剂 |
| EP2717901A4 (en) * | 2011-06-06 | 2015-01-21 | Women And Infants Hospital Of Rhode Island | HE4-BASED THERAPY FOR MALIGNINE DISEASES |
| DE102012205164B4 (de) | 2012-03-29 | 2021-09-09 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Projektionsdisplay und Verfahren zur Projektion virtueller Bilder |
| CN103575902B (zh) * | 2012-08-03 | 2015-07-29 | 河南生生医疗器械有限公司 | 一种时间分辨荧光法四项综合检测卵巢癌试剂盒及其应用 |
| CN102890083B (zh) * | 2012-09-28 | 2016-08-10 | 辽宁科骏生物有限公司 | 化学发光底物溶液和含其的试剂盒及应用其的检测方法 |
| CN104655858B (zh) * | 2015-03-12 | 2016-02-10 | 德迈基生物技术(北京)有限公司 | 定量检测人附睾分泌蛋白-4的荧光免疫层析试剂盒及其制备方法 |
| EP3273974A4 (en) | 2015-03-26 | 2018-11-07 | Women and Infants Hospital of Rhode Island Inc. | Therapy for malignant disease |
| RU2585959C1 (ru) * | 2015-06-22 | 2016-06-10 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ дифференциальной диагностики асцитно-инфильтративной формы рака яичников и абдоминального туберкулёза |
| US10267802B2 (en) | 2015-09-23 | 2019-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of prognosis and diagnosis of ovarian cancer |
| RU2624508C1 (ru) * | 2016-06-29 | 2017-07-04 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ прогнозирования длительности ремиссии у больных раком вульвы |
| EP3482205A1 (en) | 2016-07-08 | 2019-05-15 | H. Hoffnabb-La Roche Ag | Use of human epididymis protein 4 (he4) for assessing responsiveness of muc 16-positive cancer treatment |
| US20230159586A1 (en) | 2020-04-21 | 2023-05-25 | University Of Rochester | Inhibitors of human epididymus protein 4 |
| CN111781364B (zh) * | 2020-08-25 | 2023-07-21 | 北京信诺卫康科技有限公司 | Wnt7a和HE4联合用作早期卵巢癌生物标志物以及试剂盒 |
| WO2022140116A1 (en) | 2020-12-21 | 2022-06-30 | Freenome Holdings, Inc. | Markers for the early detection of colon cell proliferative disorders |
| WO2023195629A1 (ko) * | 2022-04-08 | 2023-10-12 | 아주대학교산학협력단 | He4 검출용 펩타이드 및 그 용도 |
| WO2023195628A1 (ko) * | 2022-04-08 | 2023-10-12 | 아주대학교산학협력단 | Ca125 검출용 펩타이드 및 그 용도 |
| CN120254284B (zh) * | 2025-06-03 | 2025-08-22 | 杭州广科安德生物科技有限公司 | 一种用于预测子宫内膜癌复发或转移风险的生物标志物及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| CA1289880C (en) * | 1985-12-06 | 1991-10-01 | Jeffrey L. Winkelhake | Anti-human ovarian cancer immunotoxins and methods of use thereof |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| JPH02500329A (ja) | 1987-05-21 | 1990-02-08 | クリエイテイブ・バイオマリキユールズ・インコーポレーテツド | ターゲット化多機能蛋白質 |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| US6998106B1 (en) * | 1998-12-01 | 2006-02-14 | Duke University | Radioconjugation of internalizing antibodies |
| CA2369433A1 (en) | 1999-02-26 | 2000-08-31 | Pacific Northwest Research Institute | Methods and compositions for diagnosing carcinomas |
| US6770445B1 (en) * | 1999-02-26 | 2004-08-03 | Pacific Northwest Research Institute | Methods and compositions for diagnosing carcinomas |
| US20020182619A1 (en) * | 2000-11-08 | 2002-12-05 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of ovarian cancer |
| US7270960B2 (en) * | 2001-08-29 | 2007-09-18 | Pacific Northwest Research Institute | Diagnosis of ovarian carcinomas |
| US20030226155A1 (en) * | 2001-08-30 | 2003-12-04 | Biorexis Pharmaceutical Corporation | Modified transferrin-antibody fusion proteins |
| DK1540010T3 (da) * | 2002-08-06 | 2010-07-26 | Univ Johns Hopkins | Anvendelse af biomarkører til påvisning af ovariecancer |
| AU2003269968A1 (en) * | 2002-08-16 | 2004-03-11 | Clinical Microarrays, Inc. | Substrates for isolating, reacting and microscopically analyzing materials |
| AU2003290773A1 (en) * | 2003-02-05 | 2004-09-06 | Ciphergen Biosystems, Inc. | Non-invasive assessment of intra-amniotic environment |
| EP1633784B1 (en) * | 2003-05-09 | 2011-07-13 | Diadexus, Inc. | Ovr110 antibody compositions and methods of use |
| CN1266475C (zh) * | 2003-06-05 | 2006-07-26 | 马旭 | 一种用于诊断早期卵巢癌的四粘蛋白酶联免疫检测试剂盒 |
| EP1723428A2 (en) * | 2004-02-19 | 2006-11-22 | Yale University Corporation | Identification of cancer protein biomarkers using proteomic techniques |
| WO2005098446A2 (en) * | 2004-03-31 | 2005-10-20 | The Johns Hopkins University | Biomarkers for ovarian cancer |
| US8486648B2 (en) * | 2005-02-16 | 2013-07-16 | Dana-Farber Cancer Institute, Inc. | Methods of detecting ovarian cancer |
| US20070172902A1 (en) * | 2005-06-22 | 2007-07-26 | The Johns Hopkins University, a non-profit organization | Biomarker for ovarian cancer |
| EP1910821B1 (en) * | 2005-06-24 | 2013-02-20 | Ciphergen Biosystems, Inc. | Biomarkers for ovarian cancer |
| EP2982761B1 (en) * | 2006-01-04 | 2017-10-04 | Fujirebio America, Inc. | Use of he4 and other biochemical markers for assessment of endometrial and uterine cancers |
-
2007
- 2007-01-04 EP EP15175154.2A patent/EP2982761B1/en active Active
- 2007-01-04 JP JP2008549562A patent/JP5164855B2/ja active Active
- 2007-01-04 EP EP15175155.9A patent/EP3026119B1/en active Active
- 2007-01-04 ES ES15175154.2T patent/ES2650244T3/es active Active
- 2007-01-04 US US11/650,573 patent/US20080020473A1/en not_active Abandoned
- 2007-01-04 EP EP11168962A patent/EP2423321A3/en not_active Withdrawn
- 2007-01-04 EP EP07717677A patent/EP1846768A4/en not_active Withdrawn
- 2007-01-04 CN CN200780007130.6A patent/CN101460630B/zh active Active
- 2007-01-04 PL PL15175154T patent/PL2982761T3/pl unknown
- 2007-01-04 JP JP2008549563A patent/JP5221381B2/ja active Active
- 2007-01-04 WO PCT/US2007/000216 patent/WO2007081768A2/en not_active Ceased
- 2007-01-04 ES ES15175155T patent/ES2748397T3/es active Active
- 2007-01-04 US US11/650,337 patent/US20070286865A1/en not_active Abandoned
- 2007-01-04 CN CN200780007052.XA patent/CN101473041B/zh active Active
- 2007-01-04 WO PCT/US2007/000215 patent/WO2007081767A2/en not_active Ceased
- 2007-01-04 CN CN201610512072.3A patent/CN106124765A/zh active Pending
- 2007-01-04 EP EP07717842A patent/EP1969136A4/en not_active Withdrawn
- 2007-01-04 EP EP11171015A patent/EP2420576A3/en not_active Withdrawn
-
2012
- 2012-10-12 JP JP2012226640A patent/JP5711196B2/ja active Active
-
2018
- 2018-01-29 US US15/882,647 patent/US20180156805A1/en not_active Abandoned
- 2018-02-14 US US15/896,735 patent/US20180180620A1/en not_active Abandoned
-
2020
- 2020-02-04 US US16/781,017 patent/US20200292549A1/en not_active Abandoned
- 2020-02-12 US US16/788,442 patent/US20200182878A1/en not_active Abandoned
-
2023
- 2023-10-26 US US18/495,310 patent/US20240230652A9/en active Pending
-
2024
- 2024-04-08 US US18/629,164 patent/US20240288434A1/en active Pending
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