JP5164855B2 - 子宮内膜または子宮癌を評価するためのｈｅ４及びそのほかの生化学的マーカーの使用 - Google Patents
子宮内膜または子宮癌を評価するためのｈｅ４及びそのほかの生化学的マーカーの使用 Download PDFInfo
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
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- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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| US7270960B2 (en) | 2001-08-29 | 2007-09-18 | Pacific Northwest Research Institute | Diagnosis of ovarian carcinomas |
| WO2006119155A2 (en) * | 2005-05-02 | 2006-11-09 | The Brigham And Women's Hospital, Inc. | Diagnostic serum antibody profiling |
| CN101473041B (zh) | 2006-01-04 | 2017-11-14 | 富士瑞必欧美国公司 | He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用 |
| CA2637446A1 (en) * | 2006-01-27 | 2007-08-09 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
| US8329399B2 (en) | 2006-10-27 | 2012-12-11 | Siu K W Michael | Endometrial biomarkers |
| WO2008112514A1 (en) * | 2007-03-09 | 2008-09-18 | Tripath Imaging, Inc. | He4 monoclonal antibodies and methods for their use |
| ES2411921T3 (es) * | 2007-03-29 | 2013-07-09 | Fujirebio Diagnostics, Inc. | Uso de HE4 para la evaluación de cánceres de mama |
| CN101377502A (zh) * | 2007-08-31 | 2009-03-04 | 北京科美东雅生物技术有限公司 | 肿瘤相关抗原72-4化学发光免疫分析测定试剂盒及其制备方法 |
| US8642347B2 (en) * | 2008-01-31 | 2014-02-04 | The Brigham And Women's Hospital, Inc. | Urinary CA125 peptides as biomarkers of ovarian cancer |
| WO2009145815A2 (en) * | 2008-04-01 | 2009-12-03 | The Brigham And Women's Hospital, Inc. | Biomarkers of ovarian cancer |
| EP2609429B1 (en) * | 2010-08-26 | 2017-09-20 | University Of Washington Through Its Center For Commercialization | Methods for detecting anti-he4 antibodies and methods of diagnosis and/or prognosis of conditions associated with he4-expressing cells |
| BR112013021056B1 (pt) | 2011-02-17 | 2022-03-29 | Pujirebio Diagnostics, Inc | Anticorpo monoclonal, kit, e, método para diagnosticar um indivíduo com câncer ovariano |
| KR20140024860A (ko) * | 2011-02-24 | 2014-03-03 | 버밀리언, 인코포레이티드 | 난소암에 대한 바이오마커 패널，진단 방법 및 시험 키트 |
| CN102735840B (zh) * | 2011-04-13 | 2014-06-04 | 中国医学科学院肿瘤研究所 | 用于诊断或筛查卵巢癌的试剂 |
| WO2012170513A2 (en) * | 2011-06-06 | 2012-12-13 | Women & Infants' Hospital Of Rhode Island | He4 based therapy for malignant disease |
| DE102012205164B4 (de) | 2012-03-29 | 2021-09-09 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Projektionsdisplay und Verfahren zur Projektion virtueller Bilder |
| CN103575902B (zh) * | 2012-08-03 | 2015-07-29 | 河南生生医疗器械有限公司 | 一种时间分辨荧光法四项综合检测卵巢癌试剂盒及其应用 |
| CN102890083B (zh) * | 2012-09-28 | 2016-08-10 | 辽宁科骏生物有限公司 | 化学发光底物溶液和含其的试剂盒及应用其的检测方法 |
| CN104655858B (zh) * | 2015-03-12 | 2016-02-10 | 德迈基生物技术（北京）有限公司 | 定量检测人附睾分泌蛋白-4的荧光免疫层析试剂盒及其制备方法 |
| WO2016154629A1 (en) | 2015-03-26 | 2016-09-29 | Woman & Infants' Hospital Of Rhode Island | Therapy for malignant disease |
| RU2585959C1 (ru) * | 2015-06-22 | 2016-06-10 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ дифференциальной диагностики асцитно-инфильтративной формы рака яичников и абдоминального туберкулёза |
| US10267802B2 (en) | 2015-09-23 | 2019-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of prognosis and diagnosis of ovarian cancer |
| RU2624508C1 (ru) * | 2016-06-29 | 2017-07-04 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ прогнозирования длительности ремиссии у больных раком вульвы |
| TW202434291A (zh) | 2016-07-08 | 2024-09-01 | 美商建南德克公司 | 人類副睪蛋白4 (he4)用於評定癌症治療反應性之用途 |
| WO2021216670A1 (en) | 2020-04-21 | 2021-10-28 | University Of Rochester | Inhibitors of human epididymus protein 4 |
| CN111781364B (zh) * | 2020-08-25 | 2023-07-21 | 北京信诺卫康科技有限公司 | Wnt7a和HE4联合用作早期卵巢癌生物标志物以及试剂盒 |
| JP2024505333A (ja) | 2020-12-21 | 2024-02-06 | フリーノム ホールディングス，インク． | 結腸細胞増殖障害の早期検出のためのマーカー |
| US20240385195A1 (en) * | 2022-04-08 | 2024-11-21 | Ajou University Industry-Academic Cooperation Foundation | Peptide for detecting ca125 and use thereof |
| WO2023195629A1 (ko) * | 2022-04-08 | 2023-10-12 | 아주대학교산학협력단 | He4 검출용 펩타이드 및 그 용도 |
| CN120254284B (zh) * | 2025-06-03 | 2025-08-22 | 杭州广科安德生物科技有限公司 | 一种用于预测子宫内膜癌复发或转移风险的生物标志物及其应用 |
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| CN101473041B (zh) | 2006-01-04 | 2017-11-14 | 富士瑞必欧美国公司 | He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用 |
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