JP2012505305A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012505305A5 JP2012505305A5 JP2011531565A JP2011531565A JP2012505305A5 JP 2012505305 A5 JP2012505305 A5 JP 2012505305A5 JP 2011531565 A JP2011531565 A JP 2011531565A JP 2011531565 A JP2011531565 A JP 2011531565A JP 2012505305 A5 JP2012505305 A5 JP 2012505305A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- methacrylate
- poly
- ethylene glycol
- acrylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 74
- 229920000642 polymer Polymers 0.000 claims 58
- 239000000178 monomer Substances 0.000 claims 37
- 239000002245 particle Substances 0.000 claims 32
- 238000000034 method Methods 0.000 claims 26
- 229920002818 (Hydroxyethyl)methacrylate Polymers 0.000 claims 21
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 13
- -1 alkylene glycol methacrylate Chemical compound 0.000 claims 13
- 125000002947 alkylene group Chemical group 0.000 claims 13
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 13
- 238000006116 polymerization reaction Methods 0.000 claims 13
- 229920001223 polyethylene glycol Polymers 0.000 claims 12
- 229920001451 polypropylene glycol Polymers 0.000 claims 12
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 8
- 239000012736 aqueous medium Substances 0.000 claims 5
- 229920002988 biodegradable polymer Polymers 0.000 claims 4
- 239000004621 biodegradable polymer Substances 0.000 claims 4
- 230000005496 eutectics Effects 0.000 claims 4
- 230000001747 exhibiting effect Effects 0.000 claims 4
- 239000012620 biological material Substances 0.000 claims 3
- 238000009792 diffusion process Methods 0.000 claims 3
- 238000004945 emulsification Methods 0.000 claims 3
- 238000004381 surface treatment Methods 0.000 claims 3
- 239000004094 surface-active agent Substances 0.000 claims 3
- 238000007740 vapor deposition Methods 0.000 claims 3
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 229960000074 biopharmaceutical Drugs 0.000 claims 2
- 230000036760 body temperature Effects 0.000 claims 2
- 230000010261 cell growth Effects 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000013355 food flavoring agent Nutrition 0.000 claims 2
- 239000003205 fragrance Substances 0.000 claims 2
- 239000003102 growth factor Substances 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000011859 microparticle Substances 0.000 claims 2
- 210000000056 organ Anatomy 0.000 claims 2
- 229920000747 poly(lactic acid) Polymers 0.000 claims 2
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 150000003254 radicals Chemical class 0.000 claims 2
- 230000001172 regenerating effect Effects 0.000 claims 2
- 229940126586 small molecule drug Drugs 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 230000008467 tissue growth Effects 0.000 claims 2
- 238000013270 controlled release Methods 0.000 claims 1
- 239000011557 critical solution Substances 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 230000009969 flowable effect Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0818747.8A GB0818747D0 (en) | 2008-10-13 | 2008-10-13 | Biocompatible responsive materials |
| GB0818747.8 | 2008-10-13 | ||
| PCT/GB2009/051362 WO2010043892A1 (en) | 2008-10-13 | 2009-10-13 | Polymer particles prepared from polymerisable alkylene glycol (meth) acrylate monomers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012505305A JP2012505305A (ja) | 2012-03-01 |
| JP2012505305A5 true JP2012505305A5 (https=) | 2013-07-25 |
| JP5718815B2 JP5718815B2 (ja) | 2015-05-13 |
Family
ID=40083948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011531565A Active JP5718815B2 (ja) | 2008-10-13 | 2009-10-13 | 重合可能なアルキレングリコール（メタ）アクリレートモノマーから調製されるポリマー粒子 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8940336B2 (https=) |
| EP (1) | EP2346914B1 (https=) |
| JP (1) | JP5718815B2 (https=) |
| DK (1) | DK2346914T3 (https=) |
| ES (1) | ES2573941T3 (https=) |
| GB (1) | GB0818747D0 (https=) |
| WO (1) | WO2010043892A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG189650A1 (en) * | 2011-10-17 | 2013-05-31 | Agency Science Tech & Res | Copolymers |
| WO2014013238A1 (en) | 2012-07-16 | 2014-01-23 | The University Of Nottingham | Scaffold |
| US9205175B2 (en) | 2012-07-27 | 2015-12-08 | Drexel University | Thermosensitive and crosslinkable polymer composite for three-dimensional soft tissue scaffold printing |
| SG11201700615QA (en) * | 2014-08-19 | 2017-02-27 | Univ Singapore | Thermogelling graft copolymer and method of preparation thereof |
| JP5874859B1 (ja) * | 2014-12-12 | 2016-03-02 | 東洋インキＳｃホールディングス株式会社 | 体液接触用医療用具および生体適合性重合体 |
| JP6815719B2 (ja) * | 2015-05-11 | 2021-01-20 | ポーラ化成工業株式会社 | 海島構造を有する被膜及びこれを形成する組成物 |
| WO2019236769A1 (en) * | 2018-06-05 | 2019-12-12 | University Of Mississippi Medical Center | Production of sized macro- and micro- elp particles for drug delivery |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62224290A (ja) * | 1986-03-26 | 1987-10-02 | Hitachi Chem Co Ltd | 微生物菌体固定化法 |
| US5173421A (en) | 1988-12-14 | 1992-12-22 | Mitsubishi Kasei Corporation | Cell culture carriers |
| US20040195710A1 (en) * | 1990-10-15 | 2004-10-07 | Hubbell Jeffrey A. | Gels for encapsulation of biological materials |
| US6103528A (en) * | 1998-04-17 | 2000-08-15 | Battelle Memorial Institute | Reversible gelling culture media for in-vitro cell culture in three-dimensional matrices |
| JP2001261845A (ja) * | 2000-03-14 | 2001-09-26 | Mitsubishi Chemicals Corp | ハイドロゲル微粒子 |
| FR2810669B1 (fr) | 2000-06-27 | 2002-08-30 | Atofina | Copolymeres hydrosolubles thermosensibles a base de (meth) acrylate (poly)ethoxyle, leur fabrication et leur utilisation pour la preparation de film, adhesifs et liants pour nappes fibreuses |
| JP2004087228A (ja) * | 2002-08-26 | 2004-03-18 | Teijin Ltd | リチウムイオン二次電池 |
| GB0228537D0 (en) * | 2002-12-06 | 2003-01-15 | Syngenta Ltd | Particulate suspensions |
| JP4746984B2 (ja) | 2003-03-28 | 2011-08-10 | 独立行政法人科学技術振興機構 | 生体適合性と温度応答性を併せ持つ高分子 |
| JP4294506B2 (ja) | 2004-01-30 | 2009-07-15 | 株式会社クラレ | 感熱ゲル化性エマルジョン |
| WO2007069272A2 (en) | 2005-10-21 | 2007-06-21 | Panacea Biotec Limited | Pharmaceutical composition comprising at least one anticancer drug and at least one polymer |
-
2008
- 2008-10-13 GB GBGB0818747.8A patent/GB0818747D0/en not_active Ceased
-
2009
- 2009-10-13 ES ES09748135.2T patent/ES2573941T3/es active Active
- 2009-10-13 EP EP09748135.2A patent/EP2346914B1/en not_active Not-in-force
- 2009-10-13 WO PCT/GB2009/051362 patent/WO2010043892A1/en not_active Ceased
- 2009-10-13 US US13/123,737 patent/US8940336B2/en not_active Expired - Fee Related
- 2009-10-13 DK DK09748135.2T patent/DK2346914T3/en active
- 2009-10-13 JP JP2011531565A patent/JP5718815B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Yuan et al. | Thermoresponsive polymers with LCST transition: synthesis, characterization, and their impact on biomedical frontiers | |
| JP2012505305A5 (https=) | ||
| Kang et al. | Modulating the molecular geometry and solution self-assembly of amphiphilic polypeptoid block copolymers by side chain branching pattern | |
| Lin et al. | Thermoresponsive hydrogels from phosphorylated ABA triblock copolymers: a potential scaffold for bone tissue engineering | |
| Singhal et al. | A review: Tailor-made hydrogel structures (classifications and synthesis parameters) | |
| Warren et al. | Polymerization-induced self-assembly of block copolymer nano-objects via RAFT aqueous dispersion polymerization | |
| Fan et al. | Formation mechanism of monodisperse, low molecular weight chitosan nanoparticles by ionic gelation technique | |
| Eral et al. | Biocompatible alginate microgel particles as heteronucleants and encapsulating vehicles for hydrophilic and hydrophobic drugs | |
| CN101265312B (zh) | 两亲性三嵌段共聚物及制备方法和应用 | |
| Xu et al. | Comb-shaped conjugates comprising hydroxypropyl cellulose backbones and low-molecular-weight poly (N-isopropylacryamide) side chains for smart hydrogels: synthesis, characterization, and biomedical applications | |
| US11602721B2 (en) | Cured biodegradable microparticles and scaffolds and methods of making and using the same | |
| Xu et al. | Double-cross-linked hydrogel strengthened by UV irradiation from a hyperbranched PEG-based trifunctional polymer | |
| Krüger et al. | A catalyst-free, temperature controlled gelation system for in-mold fabrication of microgels | |
| CN102146200A (zh) | 一种基于化学交联凝胶颗粒的温敏性水凝胶及其制备方法 | |
| Pelras et al. | Polymer nanowires with highly precise internal morphology and topography | |
| Tong et al. | Spatially restricted templated growth of poly (ε-caprolactone) from carbon nanotubes by crystallization-driven self-assembly | |
| CN102138904A (zh) | 一种自固化微球及其制备方法和应用 | |
| Tong et al. | Surfactant-mediated crystallization-driven self-assembly of crystalline/ionic complexed block copolymers in aqueous solution | |
| Himi et al. | Preparation and evaluation of stomach specific IPN hydrogels for oral drug delivery: a review | |
| JP5718815B2 (ja) | 重合可能なアルキレングリコール（メタ）アクリレートモノマーから調製されるポリマー粒子 | |
| JPWO2010101240A1 (ja) | 生分解性多孔質中空微粒子、その製造方法および用途 | |
| CN101962463B (zh) | 非水解可生物降解丙烯酸类聚合物纳米水凝胶的制备方法 | |
| CN104592510B (zh) | 侧基改性的聚氨基酸材料、其弹性水凝胶及其制备方法 | |
| US20230080504A1 (en) | Composite materials and embolization methods | |
| CN103301469A (zh) | 一种表面光滑的葡聚糖凝胶微球的制备方法 |