JP2012505151A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012505151A5 JP2012505151A5 JP2010528222A JP2010528222A JP2012505151A5 JP 2012505151 A5 JP2012505151 A5 JP 2012505151A5 JP 2010528222 A JP2010528222 A JP 2010528222A JP 2010528222 A JP2010528222 A JP 2010528222A JP 2012505151 A5 JP2012505151 A5 JP 2012505151A5
- Authority
- JP
- Japan
- Prior art keywords
- bmp
- polypeptide
- seq
- promoter
- canine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/867,919 US7846428B2 (en) | 2007-10-05 | 2007-10-05 | Articular cartilage gene therapy with recombinant vector encoding BMP-7 |
| PCT/US2008/079090 WO2009046464A1 (en) | 2007-10-05 | 2008-10-07 | Articular cartilage gene therapy with recombinant vector encoding bmp-7 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012505151A JP2012505151A (ja) | 2012-03-01 |
| JP2012505151A5 true JP2012505151A5 (https=) | 2012-04-12 |
Family
ID=40276182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528222A Pending JP2012505151A (ja) | 2007-10-05 | 2008-10-07 | Bmp−7をコードする組換えベクターを用いる関節軟骨の遺伝子治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7846428B2 (https=) |
| EP (1) | EP2205743B1 (https=) |
| JP (1) | JP2012505151A (https=) |
| CN (1) | CN102027114A (https=) |
| BR (1) | BRPI0817753A8 (https=) |
| CA (1) | CA2701215C (https=) |
| WO (1) | WO2009046464A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2784861A1 (en) * | 2009-12-21 | 2011-07-14 | Pharmathene, Inc. | Recombinant butyrylcholinesterases and truncates thereof |
| RU2516951C1 (ru) * | 2013-03-01 | 2014-05-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарёва" | Способ профилактики посттравматического артроза коленного сустава |
| PL3369435T3 (pl) | 2013-07-18 | 2020-04-30 | Xalud Therapeutics, Inc. | Kompozycja do leczenia choroby zapalnej stawów |
| EP3043825A4 (en) * | 2013-09-09 | 2017-05-03 | Figene, LLC | Gene therapy for the regeneration of chondrocytes or cartilage type cells |
| RU2771490C2 (ru) | 2016-01-13 | 2022-05-05 | Мериал, Инк. | Рекомбинантные aav векторы, экспрессирующие остеопротективные гены, включая has2 и лубрицин, пригодные при лечении остеоартрита и сходных заболеваний суставов у млекопитающих |
| EA037111B1 (ru) * | 2016-04-13 | 2021-02-08 | Юниверситейт Маастрихт | Способ лечения или предупреждения остеоартрита |
| JP7308151B2 (ja) * | 2017-04-27 | 2023-07-13 | イーライ リリー アンド カンパニー | ヒトbmp7タンパク質のバリアント |
| CN109496152B (zh) * | 2018-05-17 | 2021-06-18 | 广州蓝亮医药科技有限公司 | 癸氧喹酯组合物的肌肉内库存及其预防和治疗的方法 |
| CN112168793A (zh) * | 2020-10-26 | 2021-01-05 | 辰欣药业股份有限公司 | 一种盐酸氨溴索口腔崩解片及其制备方法 |
| US20240316219A1 (en) * | 2021-05-03 | 2024-09-26 | North Carolina State University | Compositions and methods related to the treatment of ocular diseases in equines |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5266683A (en) * | 1988-04-08 | 1993-11-30 | Stryker Corporation | Osteogenic proteins |
| US6159464A (en) * | 1990-12-20 | 2000-12-12 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints |
| AU2002311777A1 (en) * | 2001-04-17 | 2002-10-28 | Genetix Pharmaceuticals, Inc. | Method of treating arthritis using lentiviral vectors in gene therapy |
| US20040167088A1 (en) * | 2003-02-25 | 2004-08-26 | Genvec, Inc. | Method of using adenoviral vectors with increased persistence in vivo |
| US20040223953A1 (en) * | 2003-03-17 | 2004-11-11 | Hsiang-Fu Kung | Combined adeno-associated virus and adenovirus cocktail gene delivery system for high efficiency gene expression without eliciting immune response in immuno-competent subjects |
| WO2005007098A2 (en) * | 2003-07-08 | 2005-01-27 | New York University | Nucleic acid therapy to enhance cartilage repair |
| EP1660663A4 (en) * | 2003-08-12 | 2007-07-11 | Brigham & Womens Hospital | METHOD AND COMPOSITIONS FOR TISSUE REPAIR |
| EP3147296A1 (en) * | 2005-11-14 | 2017-03-29 | Merial, Inc. | Gene therapy for renal failure |
| WO2007087053A2 (en) * | 2005-12-22 | 2007-08-02 | Centocor, Inc | Bmp-7 variant compositions, methods and uses |
-
2007
- 2007-10-05 US US11/867,919 patent/US7846428B2/en not_active Expired - Fee Related
-
2008
- 2008-10-07 BR BRPI0817753A patent/BRPI0817753A8/pt not_active Application Discontinuation
- 2008-10-07 WO PCT/US2008/079090 patent/WO2009046464A1/en not_active Ceased
- 2008-10-07 EP EP08836475.7A patent/EP2205743B1/en active Active
- 2008-10-07 CA CA2701215A patent/CA2701215C/en not_active Expired - Fee Related
- 2008-10-07 JP JP2010528222A patent/JP2012505151A/ja active Pending
- 2008-10-07 CN CN2008801158299A patent/CN102027114A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012505151A5 (https=) | ||
| JP2009515529A5 (https=) | ||
| Schmelzer et al. | Elastic fibers: formation, function, and fate during aging and disease | |
| US20220281954A1 (en) | Recombinant collagen and elastin molecules and uses thereof | |
| Ogawa et al. | Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice | |
| US20180009869A1 (en) | Fusion Protein Comprising Leptin and Methods for Producing and Using the Same | |
| TWI642682B (zh) | 升糖素類似物 | |
| JP4201253B2 (ja) | 薬学的活性物質に潜在性を提供する方法 | |
| JP2009544279A5 (https=) | ||
| CS91791A3 (en) | Epithelium or epithelium precursors | |
| JP2009545313A5 (https=) | ||
| Wijffels et al. | A novel family of chitin-binding proteins from insect type 2 peritrophic matrix: cDNA sequences, chitin binding activity, and cellular localization | |
| US20200062814A1 (en) | Modified Latency Associated Protein Construct | |
| Hossain et al. | H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor | |
| US11952602B2 (en) | Variants of porcine trypsin | |
| DE69926627T2 (de) | Insulinartigen wachstumsfaktor bindendes protein -3 variante | |
| JP2018537089A5 (https=) | ||
| EP1764106A2 (en) | Use of insulin-like growth factor I for the inhibition of ischemic injury involving the liver | |
| US20090269843A1 (en) | Hemopexin fusion proteins | |
| US8703733B2 (en) | Humanized TTC and methods of use thereof | |
| JP2011507498A (ja) | アグリカナーゼ感受性切断部位を有する潜在関連タンパク質構築物 | |
| JP2025507929A5 (https=) | ||
| KR20230024471A (ko) | 분비되고 안정화된 융합 단백질 mRNA 및 이의 조성물 | |
| JP2022024242A (ja) | 標的ポリペプチド分解誘導剤 | |
| Aboutalebi et al. | Peptide and Protein Tags for the Half-Life Extension of Therapeutic Agents: A Review Article |