JP2012504590A5 - - Google Patents
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- Publication number
- JP2012504590A5 JP2012504590A5 JP2011529636A JP2011529636A JP2012504590A5 JP 2012504590 A5 JP2012504590 A5 JP 2012504590A5 JP 2011529636 A JP2011529636 A JP 2011529636A JP 2011529636 A JP2011529636 A JP 2011529636A JP 2012504590 A5 JP2012504590 A5 JP 2012504590A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- allergic
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 11
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 239000012453 solvate Substances 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 206010006458 Bronchitis chronic Diseases 0.000 claims 2
- 206010006895 Cachexia Diseases 0.000 claims 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 2
- 206010009900 Colitis ulcerative Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 2
- 206010010741 Conjunctivitis Diseases 0.000 claims 2
- 206010010744 Conjunctivitis allergic Diseases 0.000 claims 2
- 201000003883 Cystic fibrosis Diseases 0.000 claims 2
- 206010012434 Dermatitis allergic Diseases 0.000 claims 2
- 206010012442 Dermatitis contact Diseases 0.000 claims 2
- 206010014561 Emphysema Diseases 0.000 claims 2
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 206010027476 Metastases Diseases 0.000 claims 2
- 206010033645 Pancreatitis Diseases 0.000 claims 2
- 201000004681 Psoriasis Diseases 0.000 claims 2
- 206010039085 Rhinitis allergic Diseases 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 208000002205 allergic conjunctivitis Diseases 0.000 claims 2
- 201000010105 allergic rhinitis Diseases 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 208000024998 atopic conjunctivitis Diseases 0.000 claims 2
- 201000008937 atopic dermatitis Diseases 0.000 claims 2
- 208000010668 atopic eczema Diseases 0.000 claims 2
- 206010006451 bronchitis Diseases 0.000 claims 2
- 208000029771 childhood onset asthma Diseases 0.000 claims 2
- 208000007451 chronic bronchitis Diseases 0.000 claims 2
- 208000010247 contact dermatitis Diseases 0.000 claims 2
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 230000005764 inhibitory process Effects 0.000 claims 2
- 208000036971 interstitial lung disease 2 Diseases 0.000 claims 2
- 201000001441 melanoma Diseases 0.000 claims 2
- 230000009401 metastasis Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 2
- 201000008482 osteoarthritis Diseases 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 206010039083 rhinitis Diseases 0.000 claims 2
- 201000000306 sarcoidosis Diseases 0.000 claims 2
- 201000009890 sinusitis Diseases 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 230000004614 tumor growth Effects 0.000 claims 2
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 2
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 claims 1
- 229940125388 beta agonist Drugs 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 208000023504 respiratory system disease Diseases 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0818033.3A GB0818033D0 (en) | 2008-10-02 | 2008-10-02 | Novel compound |
| GB0818033.3 | 2008-10-02 | ||
| PCT/GB2009/051303 WO2010038085A2 (en) | 2008-10-02 | 2009-10-02 | P38 mapk kinase inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012504590A JP2012504590A (ja) | 2012-02-23 |
| JP2012504590A5 true JP2012504590A5 (https=) | 2013-05-16 |
| JP5571088B2 JP5571088B2 (ja) | 2014-08-13 |
Family
ID=40019929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011529636A Active JP5571088B2 (ja) | 2008-10-02 | 2009-10-02 | ｐ３８ＭＡＰキナーゼ阻害剤 |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US8293771B2 (https=) |
| EP (1) | EP2350047B1 (https=) |
| JP (1) | JP5571088B2 (https=) |
| KR (1) | KR101660266B1 (https=) |
| CN (1) | CN102203078B (https=) |
| AU (1) | AU2009299554B8 (https=) |
| CA (1) | CA2738827C (https=) |
| CL (1) | CL2011000735A1 (https=) |
| CO (1) | CO6351785A2 (https=) |
| CR (1) | CR20110230A (https=) |
| CY (1) | CY1114665T1 (https=) |
| DK (1) | DK2350047T3 (https=) |
| EA (1) | EA019590B1 (https=) |
| EC (1) | ECSP11010948A (https=) |
| ES (1) | ES2428917T3 (https=) |
| GB (1) | GB0818033D0 (https=) |
| HN (1) | HN2011000874A (https=) |
| HR (1) | HRP20130895T1 (https=) |
| ME (1) | ME01604B (https=) |
| MX (1) | MX2011003552A (https=) |
| MY (1) | MY150611A (https=) |
| NI (1) | NI201100062A (https=) |
| NZ (1) | NZ591426A (https=) |
| PE (1) | PE20110810A1 (https=) |
| PL (1) | PL2350047T3 (https=) |
| PT (1) | PT2350047E (https=) |
| RS (1) | RS52979B (https=) |
| SI (1) | SI2350047T1 (https=) |
| SM (1) | SMT201300097B (https=) |
| UA (2) | UA104731C2 (https=) |
| WO (1) | WO2010038085A2 (https=) |
| ZA (1) | ZA201103181B (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008337286B2 (en) | 2007-12-19 | 2014-08-07 | Cancer Research Technology Limited | Pyrido[2,3-b]pyrazine-8-substituted compounds and their use |
| MY159230A (en) * | 2008-10-02 | 2016-12-30 | Respivert Ltd | P38 map kinase inhibitors |
| JP5670912B2 (ja) * | 2008-12-11 | 2015-02-18 | レスピバート・リミテツド | ｐ３８ＭＡＰキナーゼ阻害剤 |
| GB0905955D0 (en) | 2009-04-06 | 2009-05-20 | Respivert Ltd | Novel compounds |
| EP2236505A1 (de) * | 2009-04-03 | 2010-10-06 | Bayer CropScience AG | Acylierte Aminopyridine und - pyridazine als Insektizide |
| GB0921730D0 (en) * | 2009-12-11 | 2010-01-27 | Respivert Ltd | Method of treatment |
| NZ601085A (en) | 2010-02-01 | 2015-04-24 | Cancer Rec Tech Ltd | 1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy |
| GB201005589D0 (en) | 2010-04-01 | 2010-05-19 | Respivert Ltd | Novel compounds |
| EP2556068B1 (en) | 2010-04-08 | 2019-01-23 | Respivert Limited | P38 map kinase inhibitors |
| WO2011124923A2 (en) | 2010-04-08 | 2011-10-13 | Respivert Limited | Novel compounds |
| GB201010196D0 (en) * | 2010-06-17 | 2010-07-21 | Respivert Ltd | Methods |
| US8933228B2 (en) | 2010-06-17 | 2015-01-13 | Respivert, Ltd. | Respiratory formulations and compounds for use therein |
| GB201010193D0 (en) * | 2010-06-17 | 2010-07-21 | Respivert Ltd | Medicinal use |
| EP2578582A1 (en) | 2011-10-03 | 2013-04-10 | Respivert Limited | 1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 MAP kinase inhibitors |
| CN103917536B (zh) | 2011-10-03 | 2016-07-06 | 瑞斯比维特有限公司 | 1-吡唑基-3-(4-((2-(苯氨基)嘧啶-4-基)氧基)萘-1-基)脲用作p38 MAP激酶抑制剂 |
| BR112014013178A2 (pt) * | 2011-12-09 | 2017-06-13 | Chiesi Farm Spa | composto, composição farmacêutica e uso de um composto |
| GB201214750D0 (en) | 2012-08-17 | 2012-10-03 | Respivert Ltd | Compounds |
| US20150225373A1 (en) | 2012-08-29 | 2015-08-13 | Respivert Limited | Kinase inhibitors |
| EP2890701B1 (en) | 2012-08-29 | 2017-03-29 | Respivert Limited | Kinase inhibitors |
| GB201215357D0 (en) | 2012-08-29 | 2012-10-10 | Respivert Ltd | Compounds |
| US20150210722A1 (en) | 2012-08-29 | 2015-07-30 | Respivert Limited | Kinase inhibitors |
| WO2014076484A1 (en) | 2012-11-16 | 2014-05-22 | Respivert Limited | Kinase inhibitors |
| EP2970190A1 (en) | 2013-03-14 | 2016-01-20 | Respivert Limited | Kinase inhibitors |
| KR102283876B1 (ko) | 2013-04-02 | 2021-07-29 | 옥슬러 액퀴지션즈 리미티드 | 키나제 저해제로서 유용한 우레아 유도체 |
| US9771353B2 (en) | 2013-04-02 | 2017-09-26 | Topivert Pharma Limited | Kinase inhibitors based upon N-alkyl pyrazoles |
| GB201320732D0 (en) | 2013-11-25 | 2014-01-08 | Cancer Rec Tech Ltd | Methods of chemical synthesis |
| GB201320729D0 (en) | 2013-11-25 | 2014-01-08 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| EP3083604A1 (en) | 2013-12-20 | 2016-10-26 | Respivert Limited | Urea derivatives useful as kinase inhibitors |
| ES2677595T3 (es) | 2014-02-14 | 2018-08-03 | Respivert Limited | Compuestos heterocíclicos aromáticos como compuestos antiinflamatorios |
| MA40774A (fr) | 2014-10-01 | 2017-08-08 | Respivert Ltd | Dérivés de diaryle-urée en tant qu'inhibiteurs de kinase p38 |
| CA3015978A1 (en) | 2016-04-06 | 2017-10-12 | Topivert Pharma Limited | Kinase inhibitors |
| GB201611712D0 (en) | 2016-07-02 | 2016-08-17 | Hvivo Services Ltd | Methods and compounds for the treatment or prevention of severe or persistent influenza |
| GB201721793D0 (en) | 2017-12-22 | 2018-02-07 | Hvivo Services Ltd | Methods and compunds for the treatment or prevention of hypercytokinemia and severe influenza |
| US11407771B2 (en) | 2018-05-30 | 2022-08-09 | Washington University | Mitogen-activated protein kinase inhibitors, methods of making, and methods of use thereof |
| KR102789258B1 (ko) * | 2022-10-26 | 2025-04-01 | (의료)길의료재단 | 신규화합물 및 이를 유효성분으로 포함하는 폐섬유화증 예방 또는 치료용 약학 조성물 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999023091A1 (en) | 1997-11-03 | 1999-05-14 | Boehringer Ingelheim Pharmaceuticals, Inc. | Aromatic heterocyclic compounds as anti-inflammatory agents |
| US7329670B1 (en) | 1997-12-22 | 2008-02-12 | Bayer Pharmaceuticals Corporation | Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas |
| US20080300281A1 (en) | 1997-12-22 | 2008-12-04 | Jacques Dumas | Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas |
| ID26328A (id) | 1997-12-22 | 2000-12-14 | Bayer Ag | Penghambat raf kinase menggunakan urea heterosiklik tersubstitusi aril dan heteroaril |
| MXPA00006233A (es) | 1997-12-22 | 2002-09-18 | Bayer Ag | Inhibicion de la actividad de la cinasa p38 utilizando ureas heterociclicas sustituidas. |
| DE69836563T2 (de) | 1997-12-22 | 2007-05-16 | Bayer Pharmaceuticals Corp., West Haven | INHIBIERUNG DER p38 KINASE-AKTIVITÄT DURCH DIE VERWENDUNG VON ARYL- UND HETEROARYL-SUBSTITUIERTEN HARNSTOFFEN |
| EP1064289A1 (en) | 1998-03-18 | 2001-01-03 | Ariad Pharmaceuticals, Inc. | Heterocyclic signal transduction inhibitors, compositions containing them |
| UA73492C2 (en) * | 1999-01-19 | 2005-08-15 | Aromatic heterocyclic compounds as antiinflammatory agents | |
| ATE312823T1 (de) | 1999-07-09 | 2005-12-15 | Boehringer Ingelheim Pharma | Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen |
| US6525046B1 (en) | 2000-01-18 | 2003-02-25 | Boehringer Ingelheim Pharmaceuticals, Inc. | Aromatic heterocyclic compounds as antiinflammatory agents |
| EP1362037A1 (en) | 2001-02-15 | 2003-11-19 | Boehringer Ingelheim Pharmaceuticals Inc. | Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents |
| WO2002092576A1 (en) | 2001-05-16 | 2002-11-21 | Boehringer Ingelheim Pharmaceuticals, Inc. | Diarylurea derivatives useful as anti-inflammatory agents |
| JP2004536845A (ja) | 2001-07-11 | 2004-12-09 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | サイトカイン媒介疾患の治療方法 |
| US20040023961A1 (en) * | 2002-02-11 | 2004-02-05 | Bayer Corporation | Aryl ureas with raf kinase and angiogenisis inhibiting activity |
| MXPA04007832A (es) | 2002-02-11 | 2005-09-08 | Bayer Pharmaceuticals Corp | Aril-ureas con actividad inhibitoria de angiogenesis. |
| ATE386030T1 (de) * | 2002-02-25 | 2008-03-15 | Boehringer Ingelheim Pharma | 1,4-disubstituierte benzokondensierte cycloalkyl- harnstoffverbindungen zur behandlung von zytokinvermittelten erkrankungen |
| AU2003224025A1 (en) | 2002-04-05 | 2003-10-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | p38 kinase inhibitors for treating mucus hypersecretion |
| US20040110755A1 (en) | 2002-08-13 | 2004-06-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | Combination therapy with p38 MAP kinase inhibitors and their pharmaceutical compositions |
| JP2006503025A (ja) | 2002-09-05 | 2006-01-26 | サイオス インク． | ｐ３８ＭＡＰキナーゼの抑制による疼痛治療 |
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| DE602004030222D1 (de) | 2003-02-28 | 2011-01-05 | Bayer Healthcare Llc | 2-oxo-1,3,5-perhydrotriazapinderivate, die sich zur behandlung von hyperproliferativen, angiogenen und entzündlichen erkrankungen eignen |
| CA2517517C (en) | 2003-03-03 | 2012-12-18 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| GB0308511D0 (en) | 2003-04-14 | 2003-05-21 | Astex Technology Ltd | Pharmaceutical compounds |
| GB0320244D0 (en) | 2003-05-06 | 2003-10-01 | Aventis Pharma Inc | Pyrazoles as inhibitors of tumour necrosis factor |
| WO2004101529A1 (ja) | 2003-05-19 | 2004-11-25 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環化合物およびその医薬用途 |
| CA2536293A1 (en) | 2003-08-22 | 2005-03-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Methods of treating copd and pulmonary hypertension |
| US20050192314A1 (en) | 2003-11-13 | 2005-09-01 | Ambit Biosciences Corporation | Urea derivatives as C-kit modulators |
| WO2006028524A2 (en) | 2004-04-29 | 2006-03-16 | Pharmix Corporation | Compositions and treatments for inhibiting kinase and/or hmg-coa reductase |
| CN101010315A (zh) | 2004-04-30 | 2007-08-01 | 拜耳制药公司 | 用于治疗癌症的取代的吡唑基脲衍生物 |
| ATE460402T1 (de) | 2004-05-12 | 2010-03-15 | Bristol Myers Squibb Co | Für die behandlung von thrombotischen leiden geeignete harnstoffantagonisten des p2y1- rezeptors |
| PT1761520E (pt) | 2004-06-23 | 2008-09-15 | Lilly Co Eli | Inibidores de quinase |
| US20060035893A1 (en) | 2004-08-07 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
| GB0423554D0 (en) | 2004-10-22 | 2004-11-24 | Cancer Rec Tech Ltd | Therapeutic compounds |
| EP1824843A2 (en) | 2004-12-07 | 2007-08-29 | Locus Pharmaceuticals, Inc. | Inhibitors of protein kinases |
| WO2006068591A1 (en) | 2004-12-20 | 2006-06-29 | Astrazeneca Ab | Novel pyrazole derivatives and their use as modulators of nicotinic acetylcholine receptors |
| WO2006071940A2 (en) | 2004-12-23 | 2006-07-06 | Deciphera Pharmaceuticals, Llc | Enzyme modulators and treatments |
| AU2005325676A1 (en) | 2004-12-23 | 2006-08-03 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| GB0500435D0 (en) | 2005-01-10 | 2005-02-16 | Novartis Ag | Organic compounds |
| DE102005015253A1 (de) | 2005-04-04 | 2006-10-05 | Merck Patent Gmbh | Pyrazolderivate |
| EP1899299B1 (en) | 2005-06-27 | 2010-10-20 | Bristol-Myers Squibb Company | C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions |
| DE102005037499A1 (de) | 2005-08-09 | 2007-02-15 | Merck Patent Gmbh | Pyrazolderivate |
| WO2007038425A2 (en) | 2005-09-27 | 2007-04-05 | Regents Of The University Of Minnesota | Anti-viral compouinds |
| EP1960394A2 (en) | 2005-11-15 | 2008-08-27 | Bayer HealthCare AG | Pyrazolyl urea derivatives useful in the treatment of cancer |
| JP2009518298A (ja) | 2005-12-01 | 2009-05-07 | バイエル ヘルスケア リミティド ライアビリティ カンパニー | 癌治療に有用な尿素化合物 |
| PE20080538A1 (es) | 2006-08-04 | 2008-06-18 | Takeda Pharmaceutical | Derivado heterociclico fusionado y su uso |
| KR101510356B1 (ko) * | 2008-07-31 | 2015-04-06 | 휴렛-팩커드 디벨롭먼트 컴퍼니, 엘.피. | 광학 신호들을 증폭, 변조 및 검출하기 위한 나노-와이어 광학 블록 디바이스들 |
| MY159230A (en) * | 2008-10-02 | 2016-12-30 | Respivert Ltd | P38 map kinase inhibitors |
| JP5670912B2 (ja) * | 2008-12-11 | 2015-02-18 | レスピバート・リミテツド | ｐ３８ＭＡＰキナーゼ阻害剤 |
-
2008
- 2008-10-02 GB GBGB0818033.3A patent/GB0818033D0/en not_active Ceased
-
2009
- 2009-10-02 MX MX2011003552A patent/MX2011003552A/es active IP Right Grant
- 2009-10-02 AU AU2009299554A patent/AU2009299554B8/en active Active
- 2009-10-02 DK DK09736271.9T patent/DK2350047T3/da active
- 2009-10-02 EP EP09736271.9A patent/EP2350047B1/en active Active
- 2009-10-02 PT PT97362719T patent/PT2350047E/pt unknown
- 2009-10-02 MY MYPI20111436 patent/MY150611A/en unknown
- 2009-10-02 CA CA2738827A patent/CA2738827C/en active Active
- 2009-10-02 KR KR1020117009956A patent/KR101660266B1/ko active Active
- 2009-10-02 WO PCT/GB2009/051303 patent/WO2010038085A2/en not_active Ceased
- 2009-10-02 US US13/121,445 patent/US8293771B2/en active Active
- 2009-10-02 PL PL09736271T patent/PL2350047T3/pl unknown
- 2009-10-02 JP JP2011529636A patent/JP5571088B2/ja active Active
- 2009-10-02 ME MEP-2013-108A patent/ME01604B/me unknown
- 2009-10-02 CN CN200980139617.9A patent/CN102203078B/zh active Active
- 2009-10-02 HR HRP20130895AT patent/HRP20130895T1/hr unknown
- 2009-10-02 UA UAA201103554A patent/UA104731C2/ru unknown
- 2009-10-02 UA UAA201103555A patent/UA105014C2/uk unknown
- 2009-10-02 EA EA201170520A patent/EA019590B1/ru not_active IP Right Cessation
- 2009-10-02 PE PE2011000798A patent/PE20110810A1/es not_active Application Discontinuation
- 2009-10-02 NZ NZ591426A patent/NZ591426A/xx unknown
- 2009-10-02 SI SI200930725T patent/SI2350047T1/sl unknown
- 2009-10-02 ES ES09736271T patent/ES2428917T3/es active Active
- 2009-10-02 RS RS20130407A patent/RS52979B/sr unknown
-
2011
- 2011-03-25 CO CO11037006A patent/CO6351785A2/es active IP Right Grant
- 2011-04-01 EC EC2011010948A patent/ECSP11010948A/es unknown
- 2011-04-01 CL CL2011000735A patent/CL2011000735A1/es unknown
- 2011-04-01 HN HN2011000874A patent/HN2011000874A/es unknown
- 2011-04-01 NI NI201100062A patent/NI201100062A/es unknown
- 2011-04-29 ZA ZA2011/03181A patent/ZA201103181B/en unknown
- 2011-05-02 CR CR20110230A patent/CR20110230A/es unknown
-
2013
- 2013-09-05 SM SM201300097T patent/SMT201300097B/xx unknown
- 2013-09-25 CY CY20131100835T patent/CY1114665T1/el unknown
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