JP2012503673A5 - - Google Patents
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- Publication number
- JP2012503673A5 JP2012503673A5 JP2011529272A JP2011529272A JP2012503673A5 JP 2012503673 A5 JP2012503673 A5 JP 2012503673A5 JP 2011529272 A JP2011529272 A JP 2011529272A JP 2011529272 A JP2011529272 A JP 2011529272A JP 2012503673 A5 JP2012503673 A5 JP 2012503673A5
- Authority
- JP
- Japan
- Prior art keywords
- beads
- calcium
- microspheres
- minerals
- coated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000011324 bead Substances 0.000 claims 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 4
- 239000011575 calcium Substances 0.000 claims 4
- 229910052791 calcium Inorganic materials 0.000 claims 4
- 239000004005 microsphere Substances 0.000 claims 4
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 3
- 239000011707 mineral Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000002504 physiological saline solution Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10006208P | 2008-09-25 | 2008-09-25 | |
| US61/100,062 | 2008-09-25 | ||
| PCT/US2009/058419 WO2010036919A1 (en) | 2008-09-25 | 2009-09-25 | Mineral-coated microspheres |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012503673A JP2012503673A (ja) | 2012-02-09 |
| JP2012503673A5 true JP2012503673A5 (enExample) | 2012-11-15 |
Family
ID=42060103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011529272A Pending JP2012503673A (ja) | 2008-09-25 | 2009-09-25 | ミネラルコーティングされたマイクロスフェア |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11607391B2 (enExample) |
| EP (2) | EP4011363B1 (enExample) |
| JP (1) | JP2012503673A (enExample) |
| CA (1) | CA2740633C (enExample) |
| WO (1) | WO2010036919A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12171904B2 (en) | 2006-10-30 | 2024-12-24 | Trs Holdings Llc | Mineral coated scaffolds |
| WO2012071013A1 (en) | 2010-11-24 | 2012-05-31 | Nanyang Technological University | Method for encapsulating particles |
| SG10201509138XA (en) * | 2010-11-24 | 2015-12-30 | Univ Nanyang Tech | Method for coating particles with calcium phosphate and particles, microparticles and nanoparticles formed thereof |
| US20140141047A1 (en) * | 2012-11-19 | 2014-05-22 | Wisconsin Alumni Research Foundation | Selection of platelet rich plasma components via mineral binding |
| CA2925087C (en) * | 2013-09-24 | 2024-02-13 | The Feinstein Institute For Medical Research | Peptides inhibiting cold-inducible rna binding protein activity |
| CN103611193B (zh) * | 2013-11-26 | 2015-05-27 | 中山大学 | 一种碳酸钙微球-细胞外基质复合材料及其制备方法和应用 |
| US10682442B2 (en) | 2014-04-04 | 2020-06-16 | University Of Kentucky Research Foundation | Small molecule drug release from in situ forming degradable scaffolds incorporating hydrogels and bioceramic microparticles |
| US20150306595A1 (en) * | 2014-04-25 | 2015-10-29 | The Trustees Of Princeton University | Nanoparticulate Apatite Coated Calcite/Limestone Filter Materials for Removing Contaminants from Contaminated Water |
| WO2016141242A1 (en) * | 2015-03-03 | 2016-09-09 | Tissue Regeneration Systems, Inc. | Coating scaffolds |
| US10449155B2 (en) * | 2015-11-09 | 2019-10-22 | Medical Corporation Ijunkai | Drug introducing agent for administration into a living body and manufacturing method |
| EP3606512A4 (en) * | 2017-04-03 | 2021-01-13 | Wisconsin Alumni Research Foundation | MINERAL COATED MICROPARTICLES INTENDED FOR THE PROLONGED DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES |
| US11628227B2 (en) | 2017-07-05 | 2023-04-18 | Wisconsin Alumni Research Foundation | Mineral coated microparticles for gene delivery in chronic wound therapy |
| CN107823189B (zh) * | 2017-11-25 | 2021-04-06 | 杭州高成生物营养技术有限公司 | 一种氯化钾缓释微丸及其制备方法与应用 |
| US12465573B2 (en) | 2018-04-06 | 2025-11-11 | Wisconsin Alumni Research Foundation | Structured nanocoatings for the stabilization of pluripotent stem cell media components |
| JP2021523151A (ja) * | 2018-05-11 | 2021-09-02 | ホスホレックス、インコーポレイテッド | 負の表面電荷を有するマイクロ粒子及びナノ粒子 |
| AU2020274535A1 (en) * | 2019-05-10 | 2021-12-09 | Commonwealth Scientific And Industrial Research Organisation | Microcapsule |
| EP4027949A4 (en) | 2019-09-11 | 2023-06-14 | Warsaw Orthopedic, Inc. | HYDRATABLE COMPOSITIONS COMPRISING MACROPARTICLES AND METHODS OF MAKING THEM |
| WO2021240539A1 (en) * | 2020-05-25 | 2021-12-02 | SHREY, Dhawan | Ion-substituted bovine hydroxyapatite for bone regeneration |
| CN113425896A (zh) * | 2021-05-08 | 2021-09-24 | 上海大学 | 用于牙槽骨缺损修复的聚氨基酸微载体及其制备方法 |
| CN113769162B (zh) * | 2021-09-14 | 2022-09-13 | 武汉大学 | 一种用于治疗感染性骨缺损的负载聚乙烯吡咯烷酮碘的仿生矿化微球的制备方法 |
| WO2023086816A1 (en) * | 2021-11-09 | 2023-05-19 | Wisconsin Alumni Research Foundation | Mineral-coated substrates for stabilization of rna-based therapeutic compositions |
| US11747269B2 (en) | 2021-11-09 | 2023-09-05 | Warsaw Orthopedic, Inc. | Systems and methods for identifying a coating on an implant |
| US12048628B2 (en) | 2021-11-09 | 2024-07-30 | Warsaw Orthopedic, Inc. | Systems and methods of coating bone material |
| US20230390070A1 (en) | 2022-06-07 | 2023-12-07 | Warsaw Orthopedic, Inc. | Methods and apparatus for coating bone particles using a mesh |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743779B1 (en) * | 1994-11-29 | 2004-06-01 | Imarx Pharmaceutical Corp. | Methods for delivering compounds into a cell |
| CA2285430C (en) * | 1997-04-01 | 2008-11-18 | Cap Biotechnology, Inc. | Calcium phosphate microcarriers and microspheres |
| AU8681098A (en) | 1997-08-01 | 1999-03-08 | Massachusetts Institute Of Technology | Three-dimensional polymer matrices |
| CA2370063C (en) | 1999-03-19 | 2012-10-02 | The Regents Of The University Of Michigan | Mineralization and cellular patterning on biomaterial surfaces |
| US6767928B1 (en) | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
| US7829074B2 (en) * | 2001-10-18 | 2010-11-09 | Nektar Therapeutics | Hydroxypatite-targeting poly(ethylene glycol) and related polymers |
| US6730324B2 (en) * | 2001-04-20 | 2004-05-04 | The University Of British Columbia | Biofunctional hydroxyapatite coatings and microspheres for in-situ drug encapsulation |
| US7776600B2 (en) * | 2002-04-18 | 2010-08-17 | Carnegie Mellon University | Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids |
| US7090868B2 (en) * | 2002-09-13 | 2006-08-15 | University Of Florida | Materials and methods for drug delivery and uptake |
| WO2004085998A2 (en) | 2003-03-28 | 2004-10-07 | The Children's Hospital Of Philadelphia | Biomimetic hierarchies using functionalized nanoparticles as building blocks |
| US20050249697A1 (en) * | 2003-09-24 | 2005-11-10 | Uhrich Kathryn E | Compositions and methods for the inhibition of bone growth and resorption |
| EP1729675A4 (en) * | 2004-03-05 | 2011-05-18 | Univ Columbia | MULTI-PHASE BIODEGRADABLE AND EAST-INTEGRATIVE COMPOSITE SCULPTURE FOR THE BIOLOGICAL FIXATION OF SKELETAL MOLECULAR WEAVE ON BONE |
| US20080090760A2 (en) * | 2005-12-09 | 2008-04-17 | Todd Hembrough | Compositions and Methods for Inhibiting Cellular Proliferation |
| US9295755B2 (en) | 2006-10-18 | 2016-03-29 | Wisconsin Alumni Research Foundation | Multilayer tissue regeneration system |
| US8275594B2 (en) | 2006-10-30 | 2012-09-25 | The Regents Of The University Of Michigan | Engineered scaffolds for intervertebral disc repair and regeneration and for articulating joint repair and regeneration |
| US9439948B2 (en) | 2006-10-30 | 2016-09-13 | The Regents Of The University Of Michigan | Degradable cage coated with mineral layers for spinal interbody fusion |
-
2009
- 2009-09-25 JP JP2011529272A patent/JP2012503673A/ja active Pending
- 2009-09-25 EP EP21213679.0A patent/EP4011363B1/en active Active
- 2009-09-25 WO PCT/US2009/058419 patent/WO2010036919A1/en not_active Ceased
- 2009-09-25 EP EP09816920.4A patent/EP2349212B1/en active Active
- 2009-09-25 CA CA2740633A patent/CA2740633C/en active Active
- 2009-09-25 US US13/879,178 patent/US11607391B2/en active Active
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