JP2012501646A5 - - Google Patents

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Publication number
JP2012501646A5
JP2012501646A5 JP2011526037A JP2011526037A JP2012501646A5 JP 2012501646 A5 JP2012501646 A5 JP 2012501646A5 JP 2011526037 A JP2011526037 A JP 2011526037A JP 2011526037 A JP2011526037 A JP 2011526037A JP 2012501646 A5 JP2012501646 A5 JP 2012501646A5
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JP
Japan
Prior art keywords
synaptic vesicle
platform
well
electrode pairs
vesicle cycling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2011526037A
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English (en)
Japanese (ja)
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JP5789513B2 (ja
JP2012501646A (ja
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Priority claimed from PCT/US2009/004932 external-priority patent/WO2010027446A2/en
Publication of JP2012501646A publication Critical patent/JP2012501646A/ja
Publication of JP2012501646A5 publication Critical patent/JP2012501646A5/ja
Application granted granted Critical
Publication of JP5789513B2 publication Critical patent/JP5789513B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2011526037A 2008-09-04 2009-08-31 シナプス小胞サイクリングアッセイおよびシステム Expired - Fee Related JP5789513B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9436108P 2008-09-04 2008-09-04
US61/094,361 2008-09-04
PCT/US2009/004932 WO2010027446A2 (en) 2008-09-04 2009-08-31 Synaptic vesicle cycling assays and systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015151623A Division JP6106225B2 (ja) 2008-09-04 2015-07-31 シナプス小胞サイクリングアッセイおよびシステム

Publications (3)

Publication Number Publication Date
JP2012501646A JP2012501646A (ja) 2012-01-26
JP2012501646A5 true JP2012501646A5 (enExample) 2012-10-18
JP5789513B2 JP5789513B2 (ja) 2015-10-07

Family

ID=41479300

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011526037A Expired - Fee Related JP5789513B2 (ja) 2008-09-04 2009-08-31 シナプス小胞サイクリングアッセイおよびシステム
JP2015151623A Expired - Fee Related JP6106225B2 (ja) 2008-09-04 2015-07-31 シナプス小胞サイクリングアッセイおよびシステム

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015151623A Expired - Fee Related JP6106225B2 (ja) 2008-09-04 2015-07-31 シナプス小胞サイクリングアッセイおよびシステム

Country Status (8)

Country Link
US (2) US20120053084A1 (enExample)
EP (1) EP2329275A2 (enExample)
JP (2) JP5789513B2 (enExample)
KR (1) KR20110073494A (enExample)
CN (1) CN102203622A (enExample)
AU (2) AU2009288657A1 (enExample)
CA (1) CA2744804C (enExample)
WO (1) WO2010027446A2 (enExample)

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WO2010138263A2 (en) 2009-05-28 2010-12-02 University Of Massachusetts Novel aav 's and uses thereof
CN103168236B (zh) 2010-08-23 2016-01-20 哈佛大学管理委员会 用于膜电位测定的光遗传学探针
US9207237B2 (en) 2010-08-23 2015-12-08 President And Fellows Of Harvard College Systems, methods, and workflows for optogenetics analysis
US9488637B2 (en) * 2011-01-26 2016-11-08 The Curators Of The University Of Missouri Combination of single-cell electroporation and electrical recording using the same electrode
US9226976B2 (en) 2011-04-21 2016-01-05 University Of Massachusetts RAAV-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
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US9696275B2 (en) 2012-10-12 2017-07-04 The Curators Of The University Of Missouri Addressable electrode arrays in multiple fluidic compartments and uses thereof
EP2913390B1 (en) * 2012-10-25 2020-12-09 Hamamatsu Photonics K.K. Electrical stimulation device, cell observation device and cell observation method
US9772322B2 (en) 2012-10-25 2017-09-26 Hamamatsu Photonics K.K. Cell observation device, and cell observation method
JP6370544B2 (ja) * 2013-11-11 2018-08-08 浜松ホトニクス株式会社 細胞観察装置及び細胞観察方法
EP3095853B1 (en) * 2014-01-16 2019-01-30 Hamamatsu Photonics K.K. Cell observation device, electrostimulation device, and cell observation method
US10072251B2 (en) 2014-02-19 2018-09-11 University Of Massachusetts Recombinant AAVS having useful transcytosis properties
CA3276269A1 (en) 2014-03-18 2026-03-02 University Of Massachusetts Raav-based compositions and methods for treating amyotrophic lateral sclerosis
CA2946385A1 (en) * 2014-04-22 2015-10-29 Q-State Biosciences, Inc. Diagnostic methods for neuronal disorders
US10975391B2 (en) 2014-04-25 2021-04-13 University Of Massachusetts Recombinant AAV vectors useful for reducing immunity against transgene products
EP3158338B1 (en) 2014-06-18 2020-03-11 President and Fellows of Harvard College Optogenetic probes for measuring membrane potential
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US10370432B2 (en) 2014-10-03 2019-08-06 University Of Massachusetts Heterologous targeting peptide grafted AAVS
EP3200830B1 (en) 2014-10-03 2020-09-09 University of Massachusetts High efficiency library-identified aav vectors
RU2020140209A (ru) 2014-10-21 2021-01-25 Юниверсити Оф Массачусетс Варианты рекомбинантных aav и их применения
US10077463B2 (en) 2015-01-15 2018-09-18 President And Fellows Of Harvard College Optical selection of cells
WO2016131009A1 (en) 2015-02-13 2016-08-18 University Of Massachusetts Compositions and methods for transient delivery of nucleases
US10048275B2 (en) 2015-03-13 2018-08-14 Q-State Biosciences, Inc. Cardiotoxicity screening methods
EP4491733A3 (en) * 2015-04-23 2025-03-26 University of Massachusetts Modulation of aav vector transgene expression
US11046955B2 (en) 2015-04-24 2021-06-29 University Of Massachusetts Modified AAV constructs and uses thereof
US11248212B2 (en) 2015-06-30 2022-02-15 StemoniX Inc. Surface energy directed cell self assembly
EP3362550A1 (en) 2015-10-15 2018-08-22 Stemonix Inc. Method of manufacturing cells using a hollow fiber bioreactor
WO2017070525A1 (en) 2015-10-22 2017-04-27 University Of Massachusetts Methods and compositions for treating metabolic imbalance in neurodegenerative disease
EP3364996B1 (en) 2015-10-22 2021-08-25 University of Massachusetts Prostate-targeting adeno-associated virus serotype vectors
WO2017136536A1 (en) 2016-02-02 2017-08-10 University Of Massachusetts Method to enhance the efficiency of systemic aav gene delivery to the central nervous system
WO2017139643A1 (en) 2016-02-12 2017-08-17 University Of Massachusetts Anti-angiogenic mirna therapeutics for inhibiting corneal neovascularization
EP3225279B1 (en) * 2016-03-31 2023-12-20 Université de Rennes Brain tissue stimulation apparatus and computer program
WO2017176929A1 (en) 2016-04-05 2017-10-12 University Of Massachusetts Compositions and methods for selective inhibition of grainyhead-like protein expression
WO2017181105A1 (en) 2016-04-15 2017-10-19 University Of Massachusetts Methods and compositions for treating metabolic imbalance
US11882815B2 (en) 2016-06-15 2024-01-30 University Of Massachusetts Recombinant adeno-associated viruses for delivering gene editing molecules to embryonic cells
US10457940B2 (en) 2016-09-22 2019-10-29 University Of Massachusetts AAV treatment of Huntington's disease
CA3040483A1 (en) 2016-10-13 2018-04-19 University Of Massachusetts Aav capsid designs
EP3622073A4 (en) 2017-05-09 2021-01-06 University of Massachusetts METHOD FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
US11739330B2 (en) 2017-09-22 2023-08-29 University Of Massachusetts SOD1 dual expression vectors and uses thereof
JP2021520811A (ja) 2018-04-13 2021-08-26 ユニバーシティ オブ マサチューセッツ ヘキソサミニダーゼアルファおよびベータサブユニットをコードしているバイシストロニックａａｖベクターならびにその使用
JP7065433B2 (ja) * 2018-08-14 2022-05-12 日本電信電話株式会社 電極及びその製造方法、並びに積層体
EP3861121A4 (en) 2018-10-05 2022-08-24 University of Massachusetts RAAV VECTORS FOR THE TREATMENT OF GM1 AND GM2 GANGLIOSIDOSIS
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US20220357313A1 (en) * 2021-05-04 2022-11-10 Q-State Biosciences, Inc. Drug fingerprinting
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WO2025084395A1 (ja) * 2023-10-19 2025-04-24 株式会社Jiksak Bioengineering 抗シナプトタグミン２抗体
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US7615356B2 (en) * 2000-07-10 2009-11-10 Vertex Pharmaceuticals (San Diego) Llc Ion channel assay methods
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