JP2012240911A - １−ピペリジンプロピオン酸からなる、抗シワ剤、マトリックスメタロプロテアーゼ（ｍｍｐ）抑制剤、及び／又はラミニン５産生促進剤 - Google Patents

１−ピペリジンプロピオン酸からなる、抗シワ剤、マトリックスメタロプロテアーゼ（ｍｍｐ）抑制剤、及び／又はラミニン５産生促進剤 Download PDF

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Publication number
JP2012240911A
JP2012240911A JP2011108801A JP2011108801A JP2012240911A JP 2012240911 A JP2012240911 A JP 2012240911A JP 2011108801 A JP2011108801 A JP 2011108801A JP 2011108801 A JP2011108801 A JP 2011108801A JP 2012240911 A JP2012240911 A JP 2012240911A
Authority
JP
Japan
Prior art keywords
laminin
mmp
scca1
inhibitor
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011108801A
Other languages
English (en)
Japanese (ja)
Inventor
Chika Katagiri
千華 片桐
Hanayo Matsumoto
華代 松本
Hirofumi Aoki
宏文 青木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiseido Co Ltd
Original Assignee
Shiseido Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Priority to JP2011108801A priority Critical patent/JP2012240911A/ja
Priority to PCT/JP2012/062222 priority patent/WO2012157587A1/fr
Priority to TW101117039A priority patent/TW201249471A/zh
Publication of JP2012240911A publication Critical patent/JP2012240911A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2011108801A 2011-05-13 2011-05-13 １−ピペリジンプロピオン酸からなる、抗シワ剤、マトリックスメタロプロテアーゼ（ｍｍｐ）抑制剤、及び／又はラミニン５産生促進剤 Withdrawn JP2012240911A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2011108801A JP2012240911A (ja) 2011-05-13 2011-05-13 １−ピペリジンプロピオン酸からなる、抗シワ剤、マトリックスメタロプロテアーゼ（ｍｍｐ）抑制剤、及び／又はラミニン５産生促進剤
PCT/JP2012/062222 WO2012157587A1 (fr) 2011-05-13 2012-05-11 Agent antirides, inhibiteur des métalloprotéinases matricielles (mmp) et/ou activateur de production de laminine 5 contenant chacun un propionate de 1-pipéridine
TW101117039A TW201249471A (en) 2011-05-13 2012-05-11 Anti-wrinkle agent, matrix metalloproteinase (mmp) inhibitor and/or laminin 5 production promoter, each comprising 1-piperidine propionate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011108801A JP2012240911A (ja) 2011-05-13 2011-05-13 １−ピペリジンプロピオン酸からなる、抗シワ剤、マトリックスメタロプロテアーゼ（ｍｍｐ）抑制剤、及び／又はラミニン５産生促進剤

Publications (1)

Publication Number Publication Date
JP2012240911A true JP2012240911A (ja) 2012-12-10

Family

ID=47176905

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011108801A Withdrawn JP2012240911A (ja) 2011-05-13 2011-05-13 １−ピペリジンプロピオン酸からなる、抗シワ剤、マトリックスメタロプロテアーゼ（ｍｍｐ）抑制剤、及び／又はラミニン５産生促進剤

Country Status (3)

Country Link
JP (1) JP2012240911A (fr)
TW (1) TW201249471A (fr)
WO (1) WO2012157587A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023095685A1 (fr) * 2021-11-29 2023-06-01 株式会社 資生堂 Produit cosmétique
WO2024095793A1 (fr) * 2022-11-02 2024-05-10 株式会社 資生堂 Composition

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201700026858A1 (it) * 2017-03-10 2018-09-10 Univ Degli Studi Padova Uso di inibitori delle serin proteasi, in particolare di serpinb3
WO2022128057A1 (fr) 2020-12-14 2022-06-23 Symrise Ag Médicament pour la prévention et le traitement de la dégradation du collagène dans un tissu conjonctif humain
WO2022224380A1 (fr) * 2021-04-21 2022-10-27 株式会社 資生堂 Produit cosmétique
WO2023149226A1 (fr) * 2022-02-03 2023-08-10 株式会社 資生堂 Composition de soin de la peau

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2007034750A1 (ja) * 2005-09-22 2009-03-26 株式会社資生堂 しわ改善剤
JP2009051790A (ja) * 2007-08-29 2009-03-12 Maruzen Pharmaceut Co Ltd 抗酸化剤、抗老化剤、抗炎症剤、育毛剤、抗肥満剤、及び美白剤、並びに化粧料及び美容用飲食品
JP2009091281A (ja) * 2007-10-05 2009-04-30 Pola Chem Ind Inc マトリックスメタロプロテアーゼ及びこれを含有する組成物
JP5300302B2 (ja) * 2008-03-31 2013-09-25 株式会社 資生堂 １−ピペリジンプロピオン酸及び／またはその塩を活性成分とするｓｃｃａ−１産生抑制剤
JP2011016726A (ja) * 2009-07-07 2011-01-27 Sato Pharmaceutical Co Ltd 皮膚外用組成物
JP2011068570A (ja) * 2009-09-24 2011-04-07 Maruzen Pharmaceut Co Ltd ラミニン５産生促進剤、皮膚基底膜正常化剤及び皮膚損傷回復促進剤

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023095685A1 (fr) * 2021-11-29 2023-06-01 株式会社 資生堂 Produit cosmétique
WO2024095793A1 (fr) * 2022-11-02 2024-05-10 株式会社 資生堂 Composition

Also Published As

Publication number Publication date
WO2012157587A1 (fr) 2012-11-22
TW201249471A (en) 2012-12-16

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