JP2012102105A5 - - Google Patents
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- Publication number
- JP2012102105A5 JP2012102105A5 JP2011265649A JP2011265649A JP2012102105A5 JP 2012102105 A5 JP2012102105 A5 JP 2012102105A5 JP 2011265649 A JP2011265649 A JP 2011265649A JP 2011265649 A JP2011265649 A JP 2011265649A JP 2012102105 A5 JP2012102105 A5 JP 2012102105A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- antigen
- peptide according
- hla
- cytotoxic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 150000001413 amino acids Chemical class 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 5
- 230000001939 inductive effect Effects 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 230000033115 angiogenesis Effects 0.000 claims 4
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 210000001808 exosome Anatomy 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 3
- 230000001404 mediated effect Effects 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 3
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 230000001900 immune effect Effects 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 1
- 108010088729 HLA-A*02:01 antigen Proteins 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65752705P | 2005-02-28 | 2005-02-28 | |
| US60/657,527 | 2005-02-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007529685A Division JP4931154B2 (ja) | 2005-02-28 | 2006-02-17 | 血管内皮増殖因子受容体１に由来するエピトープ・ペプチドおよびこれらのペプチドを含むワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012102105A JP2012102105A (ja) | 2012-05-31 |
| JP2012102105A5 true JP2012102105A5 (cg-RX-API-DMAC7.html) | 2013-02-28 |
| JP5789820B2 JP5789820B2 (ja) | 2015-10-07 |
Family
ID=36581423
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007529685A Expired - Fee Related JP4931154B2 (ja) | 2005-02-28 | 2006-02-17 | 血管内皮増殖因子受容体１に由来するエピトープ・ペプチドおよびこれらのペプチドを含むワクチン |
| JP2010129158A Active JP4843095B2 (ja) | 2005-02-28 | 2010-06-04 | 血管内皮増殖因子受容体１に由来するエピトープ・ペプチドおよびこれらのペプチドを含むワクチン |
| JP2011265649A Expired - Fee Related JP5789820B2 (ja) | 2005-02-28 | 2011-12-05 | 血管内皮増殖因子受容体１に由来するエピトープ・ペプチドおよびこれらのペプチドを含むワクチン |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007529685A Expired - Fee Related JP4931154B2 (ja) | 2005-02-28 | 2006-02-17 | 血管内皮増殖因子受容体１に由来するエピトープ・ペプチドおよびこれらのペプチドを含むワクチン |
| JP2010129158A Active JP4843095B2 (ja) | 2005-02-28 | 2010-06-04 | 血管内皮増殖因子受容体１に由来するエピトープ・ペプチドおよびこれらのペプチドを含むワクチン |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7919099B2 (cg-RX-API-DMAC7.html) |
| EP (4) | EP1855707B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP4931154B2 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1112867T1 (cg-RX-API-DMAC7.html) |
| DK (3) | DK1855707T3 (cg-RX-API-DMAC7.html) |
| ES (3) | ES2435650T3 (cg-RX-API-DMAC7.html) |
| PL (3) | PL1855707T3 (cg-RX-API-DMAC7.html) |
| PT (3) | PT1855707E (cg-RX-API-DMAC7.html) |
| SI (3) | SI2095822T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006093030A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103073620B (zh) | 2002-09-12 | 2014-12-10 | 肿瘤疗法科学股份有限公司 | Kdr肽和包括该肽的疫苗 |
| WO2008099908A1 (ja) * | 2007-02-16 | 2008-08-21 | Oncotherapy Science, Inc. | 脈絡膜新生血管のワクチン療法 |
| TW201109029A (en) | 2009-06-11 | 2011-03-16 | Oncotherapy Science Inc | Vaccine therapy for choroidal neovascularization |
| KR20140138900A (ko) | 2012-03-09 | 2014-12-04 | 온코세라피 사이언스 가부시키가이샤 | 펩티드를 포함한 의약 조성물 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| JP7088454B2 (ja) | 2015-12-30 | 2022-06-21 | コディアック サイエンシーズ インコーポレイテッド | 抗体および抗体複合体 |
| EP3626260A4 (en) * | 2017-05-19 | 2021-05-19 | Keio University | PEPTIDE VACCINE AND PEPTIDE VACCINE COMPOSITION FOR CRANIAL NERVOUS DISEASE |
| CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| WO2021072265A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| JPH0418667A (ja) * | 1989-07-05 | 1992-01-22 | Tohoku Nippon Denki Software Kk | 自動配送システム |
| JPH0350140A (ja) * | 1989-07-18 | 1991-03-04 | Seiko Epson Corp | 分布屈折率レンズの製造方法 |
| JP3734262B2 (ja) * | 1993-03-25 | 2006-01-11 | メルク エンド カンパニー インコーポレーテッド | 血管内皮細胞増殖因子阻害剤 |
| US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
| US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| US5922687A (en) | 1995-05-04 | 1999-07-13 | Board Of Trustees Of The Leland Stanford Junior University | Intracellular delivery of nucleic acids using pressure |
| CA2225553A1 (en) | 1995-08-03 | 1997-02-20 | Rijksuniversiteit Te Leiden | Cell derived antigen presenting vesicles |
| US5853719A (en) | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
| US6100071A (en) * | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
| WO1998004720A1 (en) | 1996-07-26 | 1998-02-05 | Sloan-Kettering Institute For Cancer Research | Method and reagents for genetic immunization |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| US6200954B1 (en) * | 1998-09-04 | 2001-03-13 | National University Of Singapore | Small peptides having potent anti-angiogenic activity |
| WO2002072627A2 (en) * | 2001-03-09 | 2002-09-19 | Callistogen Ag | Induction of anti-tumor cytotoxic t-lymphocytes in humans using peptide epitopes found by computer based algorithms for vaccination |
| FI110549B (fi) | 2001-06-29 | 2003-02-14 | Nokia Corp | Menetelmä ja järjestely liikkeen määrittämiseksi |
| US20030157101A1 (en) * | 2001-11-15 | 2003-08-21 | Carlo Gambacorti-Passerini | Immunogenic ALK peptides |
| WO2003050140A1 (fr) | 2001-12-10 | 2003-06-19 | Kyogo Itoh | Antigenes tumoraux |
| CU23178A1 (es) | 2002-04-15 | 2006-09-22 | Ct Ingenieria Genetica Biotech | INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA |
| JP2004018667A (ja) | 2002-06-17 | 2004-01-22 | National Institute Of Advanced Industrial & Technology | 高分子化合物膜の表面における炭酸カルシウム被膜の製造方法 |
| AU2003254950A1 (en) | 2002-08-26 | 2004-03-11 | Kirin Beer Kabushiki Kaisha | Peptides and drugs containing the same |
| CN103073620B (zh) | 2002-09-12 | 2014-12-10 | 肿瘤疗法科学股份有限公司 | Kdr肽和包括该肽的疫苗 |
| TW201109029A (en) | 2009-06-11 | 2011-03-16 | Oncotherapy Science Inc | Vaccine therapy for choroidal neovascularization |
-
2006
- 2006-02-17 DK DK06714491.5T patent/DK1855707T3/da active
- 2006-02-17 SI SI200631689T patent/SI2095822T1/sl unknown
- 2006-02-17 SI SI200631350T patent/SI1855707T1/sl unknown
- 2006-02-17 WO PCT/JP2006/303352 patent/WO2006093030A1/en not_active Ceased
- 2006-02-17 EP EP06714491A patent/EP1855707B1/en not_active Not-in-force
- 2006-02-17 PL PL06714491T patent/PL1855707T3/pl unknown
- 2006-02-17 PL PL09007549T patent/PL2095822T3/pl unknown
- 2006-02-17 PT PT06714491T patent/PT1855707E/pt unknown
- 2006-02-17 JP JP2007529685A patent/JP4931154B2/ja not_active Expired - Fee Related
- 2006-02-17 EP EP10177956A patent/EP2289532A1/en not_active Withdrawn
- 2006-02-17 PT PT101779601T patent/PT2289533E/pt unknown
- 2006-02-17 DK DK10177960.1T patent/DK2289533T3/da active
- 2006-02-17 PL PL10177960T patent/PL2289533T3/pl unknown
- 2006-02-17 ES ES10177960T patent/ES2435650T3/es active Active
- 2006-02-17 SI SI200631668T patent/SI2289533T1/sl unknown
- 2006-02-17 PT PT90075490T patent/PT2095822E/pt unknown
- 2006-02-17 ES ES09007549.0T patent/ES2442294T3/es active Active
- 2006-02-17 ES ES06714491T patent/ES2385396T3/es active Active
- 2006-02-17 US US11/816,893 patent/US7919099B2/en active Active
- 2006-02-17 DK DK09007549.0T patent/DK2095822T3/da active
- 2006-02-17 EP EP09007549.0A patent/EP2095822B1/en not_active Not-in-force
- 2006-02-17 EP EP10177960.1A patent/EP2289533B1/en active Active
-
2010
- 2010-06-04 JP JP2010129158A patent/JP4843095B2/ja active Active
-
2011
- 2011-03-03 US US13/040,177 patent/US8257711B2/en not_active Expired - Fee Related
- 2011-12-05 JP JP2011265649A patent/JP5789820B2/ja not_active Expired - Fee Related
-
2012
- 2012-06-12 CY CY20121100533T patent/CY1112867T1/el unknown
- 2012-08-03 US US13/566,933 patent/US8663647B2/en not_active Expired - Fee Related
-
2014
- 2014-01-21 US US14/160,436 patent/US20140186381A1/en not_active Abandoned