JP2012068259A5 - - Google Patents
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- Publication number
- JP2012068259A5 JP2012068259A5 JP2011255236A JP2011255236A JP2012068259A5 JP 2012068259 A5 JP2012068259 A5 JP 2012068259A5 JP 2011255236 A JP2011255236 A JP 2011255236A JP 2011255236 A JP2011255236 A JP 2011255236A JP 2012068259 A5 JP2012068259 A5 JP 2012068259A5
- Authority
- JP
- Japan
- Prior art keywords
- matrix
- sample
- mass spectrometry
- laser desorption
- assisted laser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011159 matrix material Substances 0.000 claims 12
- 238000003795 desorption Methods 0.000 claims 9
- 238000004949 mass spectrometry Methods 0.000 claims 9
- 238000005464 sample preparation method Methods 0.000 claims 5
- WXTMDXOMEHJXQO-UHFFFAOYSA-N 2,5-dihydroxybenzoic acid Chemical compound OC(=O)C1=CC(O)=CC=C1O WXTMDXOMEHJXQO-UHFFFAOYSA-N 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- 238000004458 analytical method Methods 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011255236A JP5705094B2 (ja) | 2006-09-28 | 2011-11-22 | マトリックス支援レーザー脱離イオン化質量分析用サンプル調製法及びマトリックス支援レーザー脱離イオン化質量分析法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006265349 | 2006-09-28 | ||
| JP2006265349 | 2006-09-28 | ||
| JP2011255236A JP5705094B2 (ja) | 2006-09-28 | 2011-11-22 | マトリックス支援レーザー脱離イオン化質量分析用サンプル調製法及びマトリックス支援レーザー脱離イオン化質量分析法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008536466A Division JPWO2008038812A1 (ja) | 2006-09-28 | 2007-09-21 | マトリックス支援レーザー脱離イオン化質量分析用サンプル調製法及びマトリックス支援レーザー脱離イオン化質量分析法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012068259A JP2012068259A (ja) | 2012-04-05 |
| JP2012068259A5 true JP2012068259A5 (enExample) | 2012-05-24 |
| JP5705094B2 JP5705094B2 (ja) | 2015-04-22 |
Family
ID=39230241
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008536466A Pending JPWO2008038812A1 (ja) | 2006-09-28 | 2007-09-21 | マトリックス支援レーザー脱離イオン化質量分析用サンプル調製法及びマトリックス支援レーザー脱離イオン化質量分析法 |
| JP2011255236A Active JP5705094B2 (ja) | 2006-09-28 | 2011-11-22 | マトリックス支援レーザー脱離イオン化質量分析用サンプル調製法及びマトリックス支援レーザー脱離イオン化質量分析法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008536466A Pending JPWO2008038812A1 (ja) | 2006-09-28 | 2007-09-21 | マトリックス支援レーザー脱離イオン化質量分析用サンプル調製法及びマトリックス支援レーザー脱離イオン化質量分析法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8283625B2 (enExample) |
| EP (1) | EP2063265B1 (enExample) |
| JP (2) | JPWO2008038812A1 (enExample) |
| WO (1) | WO2008038812A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7880139B2 (en) * | 2007-05-31 | 2011-02-01 | Georgia Tech Research Corporation | Method and apparatus of uniform gas-phase molecular matrix deposition for imaging mass spectrometry |
| EP2567395B1 (en) * | 2010-05-07 | 2019-12-18 | UT-Battelle, LLC | System and method for extracting a sample from a surface |
| US8486703B2 (en) | 2010-09-30 | 2013-07-16 | Ut-Battelle, Llc | Surface sampling concentration and reaction probe |
| US8519330B2 (en) | 2010-10-01 | 2013-08-27 | Ut-Battelle, Llc | Systems and methods for laser assisted sample transfer to solution for chemical analysis |
| US8637813B2 (en) | 2010-10-01 | 2014-01-28 | Ut-Battelle, Llc | System and method for laser assisted sample transfer to solution for chemical analysis |
| JP2013257282A (ja) * | 2012-06-14 | 2013-12-26 | Canon Inc | 画像処理方法および装置 |
| ITRM20120436A1 (it) * | 2012-09-13 | 2014-03-14 | System Optimal Solution S R L | Elemento per la realizzazione di repliche di indagini superficiali di materiali e metodo atto a realizzare tali indagini |
| WO2014041415A1 (en) * | 2012-09-13 | 2014-03-20 | System Optimal Solution S.R.L. | Element for making replicas in material surface investigations and method suited to carry out such investigations |
| KR102480335B1 (ko) | 2014-08-18 | 2022-12-21 | 벡톤 디킨슨 앤드 컴퍼니 | 매트릭스 보조 레이저 탈착 이온화를 위한 시료 제조 방법 및 이를 위한 자동화 시스템 |
| CN105973974B (zh) * | 2016-07-21 | 2019-01-11 | 浙江大学 | 一种聚硫代碳酸酯类化合物的maldi-tof-ms的检测方法 |
| EP3631461A1 (en) * | 2017-06-02 | 2020-04-08 | Verhaert, Peter Dominiek Emiel Maria | Mass spectrometry histochemistry of peptides from formaldehyde-fixed, paraffin-embedded tissue |
| JP6876881B1 (ja) * | 2019-06-28 | 2021-05-26 | 旭化成株式会社 | 質量分析計のためのイメージング用試料、及びその製法 |
| CN113219044B (zh) * | 2021-03-09 | 2023-03-24 | 中国科学院南京土壤研究所 | 一种2,5-二羟基苯甲酸用作基质的质谱成像目标物及其质谱成像方法 |
| CN119198891A (zh) * | 2024-11-22 | 2024-12-27 | 浙江大学长三角智慧绿洲创新中心 | 一种麦冬中化学成分的可视化检测方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5808300A (en) * | 1996-05-10 | 1998-09-15 | Board Of Regents, The University Of Texas System | Method and apparatus for imaging biological samples with MALDI MS |
| US6024925A (en) * | 1997-01-23 | 2000-02-15 | Sequenom, Inc. | Systems and methods for preparing low volume analyte array elements |
| DE69727489T2 (de) * | 1996-11-06 | 2004-11-25 | Sequenom, Inc., San Diego | Verfahren zur massenspektrometrie |
| US7285422B1 (en) * | 1997-01-23 | 2007-10-23 | Sequenom, Inc. | Systems and methods for preparing and analyzing low volume analyte array elements |
| US6268131B1 (en) * | 1997-12-15 | 2001-07-31 | Sequenom, Inc. | Mass spectrometric methods for sequencing nucleic acids |
| US6633031B1 (en) * | 1999-03-02 | 2003-10-14 | Advion Biosciences, Inc. | Integrated monolithic microfabricated dispensing nozzle and liquid chromatography-electrospray system and method |
| CN1402786A (zh) | 1999-05-18 | 2003-03-12 | 衣阿华研究基金大学 | 复合糖的生产 |
| JP2002107354A (ja) | 1999-09-14 | 2002-04-10 | Nippon Mitsubishi Oil Corp | 病理組織包埋剤 |
| JP3831867B2 (ja) * | 2001-02-09 | 2006-10-11 | 独立行政法人科学技術振興機構 | 試料分取方法及びそのための装置 |
| US20050019223A1 (en) * | 2001-08-10 | 2005-01-27 | Platt Albert Edward | Liquid delivery apparatus and method |
| JP2003098154A (ja) | 2001-09-21 | 2003-04-03 | Shimadzu Corp | 質量分析用サンプル調製装置 |
| DE60317305T2 (de) * | 2002-01-25 | 2008-08-28 | Innovadyne Technologies, Inc., Santa Rosa | Kontaktloses verfahren zur verteilung geringer flüssigkeitsmengen |
| US7381373B2 (en) * | 2002-06-07 | 2008-06-03 | Purdue Research Foundation | System and method for preparative mass spectrometry |
| JP4385655B2 (ja) | 2003-06-06 | 2009-12-16 | 株式会社島津製作所 | 液体分注装置 |
| CN1685238A (zh) | 2002-09-27 | 2005-10-19 | 株式会社岛津制作所 | 用于液体分注的方法及装置 |
| EP1550862B1 (en) | 2002-10-04 | 2012-01-25 | Protosera Inc. | Method of identifying an analyte by gel electrophoresis-mass spectrometry |
| JP2004212391A (ja) | 2002-12-18 | 2004-07-29 | Mie Tlo Co Ltd | 組織包埋用ワックス |
| WO2004062583A2 (en) * | 2003-01-07 | 2004-07-29 | University Of Iowa Research Foundation | Vaccine and method for preventing biofilm formation |
| US20040219588A1 (en) | 2003-04-30 | 2004-11-04 | Masaru Furuta | Method for dispensing reagents onto biological samples and method for analyzing biological samples |
| JP4457742B2 (ja) | 2003-04-30 | 2010-04-28 | 株式会社島津製作所 | 生体標本への試薬の分注方法及び生体標本の解析方法 |
| DE10348407A1 (de) * | 2003-10-17 | 2005-05-19 | Widschwendter, Martin, Prof. | Prognostische und diagnostische Marker für Zell-proliferative Erkrankungen von Brustgeweben |
| JP4148143B2 (ja) | 2004-01-19 | 2008-09-10 | 株式会社島津製作所 | 液体クロマトグラフ等の分画装置 |
| EP2439285B1 (en) * | 2004-03-31 | 2019-05-08 | The General Hospital Corporation | Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments |
| JP2006038745A (ja) | 2004-07-29 | 2006-02-09 | Mitsubishi Chemicals Corp | ペプチド類の質量分析方法及びフラーレン誘導体、並びにフラーレン−ペプチド類複合体及びその製造方法 |
| US7537766B2 (en) * | 2004-08-30 | 2009-05-26 | Wyeth | Neisseria meningitidis inner core lipo-oligosaccharide epitopes, multivalent conjugates thereof and immunogenic compositions thereof |
| US7095018B2 (en) * | 2004-12-29 | 2006-08-22 | Wisconsin Alumni Research Foundation | Deposition of samples and sample matrix for enhancing the sensitivity of matrix assisted laser desorption/ionization mass spectrometry |
| EP2071313A4 (en) | 2006-09-28 | 2012-10-31 | Shimadzu Corp | METHOD FOR THE DEEPARPARINIZATION OF PREPARATIONS EMBEDDED IN PARAFFIN AND METHOD FOR THE ANALYSIS OF PREPARATIONS EMBEDDED IN PARAFFIN |
-
2007
- 2007-09-21 JP JP2008536466A patent/JPWO2008038812A1/ja active Pending
- 2007-09-21 EP EP07828875.0A patent/EP2063265B1/en active Active
- 2007-09-21 WO PCT/JP2007/069134 patent/WO2008038812A1/ja not_active Ceased
- 2007-09-21 US US12/443,461 patent/US8283625B2/en active Active
-
2011
- 2011-11-22 JP JP2011255236A patent/JP5705094B2/ja active Active
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