JP2012012388A5 - - Google Patents
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- Publication number
- JP2012012388A5 JP2012012388A5 JP2011125191A JP2011125191A JP2012012388A5 JP 2012012388 A5 JP2012012388 A5 JP 2012012388A5 JP 2011125191 A JP2011125191 A JP 2011125191A JP 2011125191 A JP2011125191 A JP 2011125191A JP 2012012388 A5 JP2012012388 A5 JP 2012012388A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl group
- alkyl
- optionally
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- UHDUNSWZQSYJFM-UHFFFAOYSA-N CC(C=C1c2ccc[s]2)c(c(nccc2)c2cc2OC)c2C1=O Chemical compound CC(C=C1c2ccc[s]2)c(c(nccc2)c2cc2OC)c2C1=O UHDUNSWZQSYJFM-UHFFFAOYSA-N 0.000 description 1
- 0 CCC*c(c(O)c1C(C(c2c[n]cc2)=C*)O)cc2c1OCC2 Chemical compound CCC*c(c(O)c1C(C(c2c[n]cc2)=C*)O)cc2c1OCC2 0.000 description 1
- BVCSMMZPWMNBHX-UHFFFAOYSA-N CCCOc(c(C(C=C1c(cc2)ccc2OC)=C)c2C1=C)cc1c2OCC1 Chemical compound CCCOc(c(C(C=C1c(cc2)ccc2OC)=C)c2C1=C)cc1c2OCC1 BVCSMMZPWMNBHX-UHFFFAOYSA-N 0.000 description 1
- KXMXMZWNQYZEKV-UHFFFAOYSA-M CCCOc(cc(CCC1)c1c12)c1N(COP([O-])(O)=O)C=C(c(cc1)ccc1OC)C2=O Chemical compound CCCOc(cc(CCC1)c1c12)c1N(COP([O-])(O)=O)C=C(c(cc1)ccc1OC)C2=O KXMXMZWNQYZEKV-UHFFFAOYSA-M 0.000 description 1
- RVTXYORLNGJHDG-UHFFFAOYSA-N CCCOc(cc(c(F)c12)F)c1N(COP(OC(C)(C)C)(OC(C)(C)C)=O)C=C(c(cc1)ccc1OC)C2=O Chemical compound CCCOc(cc(c(F)c12)F)c1N(COP(OC(C)(C)C)(OC(C)(C)C)=O)C=C(c(cc1)ccc1OC)C2=O RVTXYORLNGJHDG-UHFFFAOYSA-N 0.000 description 1
- ZDTKAOQCCWRQKP-UHFFFAOYSA-N CCCOc(ccc(F)c12)c1N(COP(O)(O)=O)C=C(c(cc1)ccc1OC)C2=O Chemical compound CCCOc(ccc(F)c12)c1N(COP(O)(O)=O)C=C(c(cc1)ccc1OC)C2=O ZDTKAOQCCWRQKP-UHFFFAOYSA-N 0.000 description 1
- KQAOEZFARPJDRQ-UHFFFAOYSA-N CCCOc(ccc(F)c12)c1N(COP(OC(C)(C)C)(OC(C)(C)C)=O)C=C(c(c(Cl)c1)ccc1Cl)C2=O Chemical compound CCCOc(ccc(F)c12)c1N(COP(OC(C)(C)C)(OC(C)(C)C)=O)C=C(c(c(Cl)c1)ccc1Cl)C2=O KQAOEZFARPJDRQ-UHFFFAOYSA-N 0.000 description 1
- MNYBFDITJKTSSJ-UHFFFAOYSA-N CN(C1CCCCC1)c(c(N(COP(O)(O)=O)C=C1c(cc2)ccc2OC)c2C1=O)ccc2F Chemical compound CN(C1CCCCC1)c(c(N(COP(O)(O)=O)C=C1c(cc2)ccc2OC)c2C1=O)ccc2F MNYBFDITJKTSSJ-UHFFFAOYSA-N 0.000 description 1
- WMNZFXMBZZPNFE-UHFFFAOYSA-N COc(cc1)ccc1C(C(c1c(cc2)F)=O)=CN(COP(N)(O)=O)c1c2OCC1CCC1 Chemical compound COc(cc1)ccc1C(C(c1c(cc2)F)=O)=CN(COP(N)(O)=O)c1c2OCC1CCC1 WMNZFXMBZZPNFE-UHFFFAOYSA-N 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011125191A JP5769504B2 (ja) | 2010-06-04 | 2011-06-03 | 医薬 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010128756 | 2010-06-04 | ||
| JP2010128756 | 2010-06-04 | ||
| JP2011125191A JP5769504B2 (ja) | 2010-06-04 | 2011-06-03 | 医薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012012388A JP2012012388A (ja) | 2012-01-19 |
| JP2012012388A5 true JP2012012388A5 (https=) | 2014-05-08 |
| JP5769504B2 JP5769504B2 (ja) | 2015-08-26 |
Family
ID=45599243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011125191A Expired - Fee Related JP5769504B2 (ja) | 2010-06-04 | 2011-06-03 | 医薬 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5769504B2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108623562A (zh) * | 2017-03-24 | 2018-10-09 | 中国海洋大学 | 一种喹啉酮生物碱类化合物及其制备方法和应用 |
| CN108623560A (zh) * | 2017-03-24 | 2018-10-09 | 中国海洋大学 | 一种喹啉酮酸类衍生物及其制备方法和用途 |
| CN112823006B (zh) * | 2018-10-17 | 2024-09-17 | 杜克大学 | 用作神经保护剂的醌还原酶2抑制剂 |
| CA3114462A1 (en) * | 2018-10-17 | 2020-04-23 | Duke University | Quinone reductase 2 inhibitor compounds and uses thereof |
| EP4370507A1 (en) * | 2021-07-13 | 2024-05-22 | Otsuka Pharmaceutical Co., Ltd. | Hydrogenated quinoxalines |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2797444B1 (fr) * | 1999-08-13 | 2003-02-07 | Lafon Labor | Compositions pharmaceutiques comprenant des 4-quinolones |
| EP1886996A1 (en) * | 2006-08-10 | 2008-02-13 | Ferrer Internacional, S.A. | 1H-Quinolin-4-one compounds, with affinity for the GABA receptor, processes, uses and compositions |
| TWI366565B (en) * | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
| TWI492943B (zh) * | 2008-12-05 | 2015-07-21 | 大塚製藥股份有限公司 | 喹啉酮化合物及藥學組成物（二） |
-
2011
- 2011-06-03 JP JP2011125191A patent/JP5769504B2/ja not_active Expired - Fee Related
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