JP2011527339A - 眼障害を処置するためのミコフェノール酸ナトリウムのｐＨ特異的な溶液 - Google Patents
眼障害を処置するためのミコフェノール酸ナトリウムのｐＨ特異的な溶液 Download PDFInfo
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
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| PCT/IB2009/006683 WO2010004435A2 (en) | 2008-07-09 | 2009-07-09 | Formulations for treating eye disorders |
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| JP2011527339A true JP2011527339A (ja) | 2011-10-27 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015501816A (ja) * | 2011-12-07 | 2015-01-19 | ロチャル インダストリーズ エルエルピーＲｏｃｈａｌ Ｉｎｄｕｓｔｒｉｅｓ，Ｌｌｐ | 殺菌組成物及び該殺菌組成物の使用方法 |
| JP2022516099A (ja) * | 2018-12-27 | 2022-02-24 | サーフィス オフサルミクス，インコーポレイテッド | 眼科用医薬組成物及び癌表面疾患の処置方法 |
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| CN102405286A (zh) | 2008-09-22 | 2012-04-04 | 阿克赛医药公司 | 减小大小的自递送RNAi化合物 |
| WO2010090762A1 (en) | 2009-02-04 | 2010-08-12 | Rxi Pharmaceuticals Corporation | Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality |
| AU2010266539A1 (en) * | 2009-06-30 | 2012-01-19 | Allergan, Inc. | Pharmaceutical ophthalmological liquid compositions containing propionic acid derivatives as a preservative |
| CN106074591B (zh) | 2010-03-24 | 2020-01-14 | 菲奥医药公司 | 眼部症候中的rna干扰 |
| TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物 |
| BR112015021334B1 (pt) * | 2013-03-14 | 2020-04-07 | Panoptica Inc | formulação ocular tópica em suspenão e uso da mesma para tratamento e/ou melhora de uma doença do segmento posterior do olho |
| US11279934B2 (en) | 2014-04-28 | 2022-03-22 | Phio Pharmaceuticals Corp. | Methods for treating cancer using nucleic acids targeting MDM2 or MYCN |
| EP3137118A4 (en) | 2014-05-01 | 2017-11-22 | RXi Pharmaceuticals Corporation | Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules |
| CN107072203B (zh) | 2014-09-09 | 2020-07-03 | 赫雷拉 A·索利斯 | 用黑色素及其类似物、前体和衍生物治疗和预防眼部疾病、障碍和病症的方法 |
| US9789080B2 (en) * | 2015-09-04 | 2017-10-17 | Insite Vision Incorporated | Ophthalmic formulations of mycophenolic acid |
| US11766421B2 (en) | 2017-09-25 | 2023-09-26 | Surface Ophthalmics, Inc. | Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease |
| US20230158045A1 (en) * | 2017-09-25 | 2023-05-25 | Surface Ophthalmics, Inc. | Pharmaceutical compositions of mycophenolic acid and/or betamethasone for the treatment of ocular disorders |
| CN111601588A (zh) * | 2017-12-08 | 2020-08-28 | 约翰霍普金斯大学 | 用于增强粘膜表面处活性剂运输的低渗水凝胶配制物 |
| US20230144779A1 (en) * | 2019-12-20 | 2023-05-11 | Vyome Therapeutics Inc. | Formulations and method for treatment of inflammatory diseases |
| US12440510B2 (en) | 2021-05-10 | 2025-10-14 | Surface Ophthalmics, Inc. | Use of chondroitin sulfate for relieving ocular pain |
| CN117979951A (zh) | 2021-05-10 | 2024-05-03 | 瑟菲斯眼科股份有限公司 | 一种用于缓解眼部疼痛的硫酸软骨素的用途 |
| CN113519461A (zh) * | 2021-07-06 | 2021-10-22 | 江西中洪博元生物技术有限公司 | 伴刀豆球蛋白a诱导的小鼠干眼症模型的构建方法及应用 |
| CN114028334B (zh) * | 2021-12-10 | 2023-08-29 | 卓和药业集团股份有限公司 | 一种肺部给药的免疫抑制剂的制备方法 |
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| JPH0930966A (ja) * | 1995-07-24 | 1997-02-04 | Gakuzo Tamura | 眼科用新規製剤 |
| JP2007505906A (ja) * | 2003-09-19 | 2007-03-15 | アドバンスト アキュラー システムズ リミテッド | マクロライド系抗生物質及び／又はミコフェノール酸含有眼用溶液 |
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| US3880995A (en) * | 1973-05-14 | 1975-04-29 | Lilly Co Eli | Treatment of arthritis with mycophenolic acid and derivatives |
| US4686234A (en) * | 1985-11-27 | 1987-08-11 | Syntex (U.S.A) Inc. | Mycophenolic acid derivatives in the treatment of inflammatory diseases, in particular rheumatoid arthritis |
| US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
| EP0391909B1 (en) * | 1987-09-03 | 1994-08-17 | The University Of Georgia Research Foundation, Inc. | Ocular cyclosporin composition |
| US5283257A (en) * | 1992-07-10 | 1994-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating hyperproliferative vascular disease |
| US5455045A (en) * | 1993-05-13 | 1995-10-03 | Syntex (U.S.A.) Inc. | High dose formulations |
| ATE303143T1 (de) * | 1993-10-01 | 2005-09-15 | Roche Palo Alto Llc | Hochdosierte oral anzuwendende suspensionen enthaltendmycophenolat mofetil |
| ID18663A (id) * | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
| US6670398B2 (en) * | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
| US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
| US7063857B1 (en) * | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
| US6482799B1 (en) * | 1999-05-25 | 2002-11-19 | The Regents Of The University Of California | Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial |
| US20030018044A1 (en) * | 2000-02-18 | 2003-01-23 | Peyman Gholam A. | Treatment of ocular disease |
| US6489335B2 (en) * | 2000-02-18 | 2002-12-03 | Gholam A. Peyman | Treatment of ocular disease |
| GB0124953D0 (en) * | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
| GB0307553D0 (en) * | 2003-04-01 | 2003-05-07 | Novartis Ag | Organic compounds |
| US20050181018A1 (en) * | 2003-09-19 | 2005-08-18 | Peyman Gholam A. | Ocular drug delivery |
| US7083803B2 (en) * | 2003-09-19 | 2006-08-01 | Advanced Ocular Systems Limited | Ocular solutions |
| US8372814B2 (en) * | 2004-06-07 | 2013-02-12 | Ista Pharmaceuticals, Inc. | Ophthalmic formulations and uses thereof |
| CN101014584A (zh) * | 2004-07-20 | 2007-08-08 | 特瓦药厂私人有限公司 | 结晶霉酚酸钠的制备方法 |
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- 2009-07-09 CN CN2009801265755A patent/CN102099029A/zh active Pending
- 2009-07-09 JP JP2011517270A patent/JP2011527339A/ja active Pending
- 2009-07-09 CA CA2729834A patent/CA2729834A1/en not_active Abandoned
- 2009-07-09 WO PCT/IB2009/006683 patent/WO2010004435A2/en not_active Ceased
- 2009-07-09 US US12/500,399 patent/US20100010082A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0930966A (ja) * | 1995-07-24 | 1997-02-04 | Gakuzo Tamura | 眼科用新規製剤 |
| JP2007505906A (ja) * | 2003-09-19 | 2007-03-15 | アドバンスト アキュラー システムズ リミテッド | マクロライド系抗生物質及び／又はミコフェノール酸含有眼用溶液 |
Non-Patent Citations (1)
| Title |
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| SIGRID KNAPP, ET AL.: "Intraocular availability of topically applied mycophenolate mofetil in rabbits", J OCUL PHARMACOL THER., vol. 19(2), JPN6013057535, 2003, pages 181 - 92, ISSN: 0002685578 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015501816A (ja) * | 2011-12-07 | 2015-01-19 | ロチャル インダストリーズ エルエルピーＲｏｃｈａｌ Ｉｎｄｕｓｔｒｉｅｓ，Ｌｌｐ | 殺菌組成物及び該殺菌組成物の使用方法 |
| JP2022516099A (ja) * | 2018-12-27 | 2022-02-24 | サーフィス オフサルミクス，インコーポレイテッド | 眼科用医薬組成物及び癌表面疾患の処置方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102099029A (zh) | 2011-06-15 |
| WO2010004435A2 (en) | 2010-01-14 |
| CA2729834A1 (en) | 2010-01-14 |
| WO2010004435A9 (en) | 2010-08-26 |
| EP2310008A2 (en) | 2011-04-20 |
| EP2310008A4 (en) | 2014-03-05 |
| US20100010082A1 (en) | 2010-01-14 |
| WO2010004435A3 (en) | 2010-06-24 |
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