JP2011523566A - 中枢神経系を刺激するためのアジテーター - Google Patents
中枢神経系を刺激するためのアジテーター Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/56—Devices for preventing snoring
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Description
本特許出願は、参照によってその全体が本出願に組み込まれる2008年5月2日に出願された米国仮出願シリアル番号61/049,802に対する優先権の利益を主張する。
この発明は広く神経障害の分野に関し、より具体的には睡眠医学の領域に関し、さらに具体的には、閉塞性睡眠時無呼吸症、中枢性睡眠時無呼吸症、複合性睡眠時無呼吸症(complex sleep apnea)、不穏下肢症候群(RLS)、乳幼児突然死症候群(SIDS)、および、睡眠中に起こるこれらに関連する生理学的現象また状態といった睡眠障害を患う患者のための睡眠治療(sleep therapy)の領域に関する。特に、本発明は、睡眠障害を患う患者の中枢神経を刺激するための装置に関する。
以下の詳細な説明は、睡眠障害を持つ患者の睡眠研究室における治療を目的とするアジテーターに関する。アジテーターは、より具体的には、患者を刺激して、いびき、睡眠時無呼吸、乳幼児突然死症候群(SIDS)、およびその他といった、望ましくない睡眠行動および睡眠コンディションを中断させるおよび止めさせることを目的とする。アジテーターは、患者に付けられたセンサ、およびコントローラと共に使い得る。センサは、情報を分析し受信した情報に基づいてアジテーターを起動し得るコントローラに呼吸に関する情報を送信する。
Claims (20)
- 睡眠障害を患う患者の中枢神経系を刺激するためのアジテーター装置であって、
前記患者の耳の中で、耳に触れた状態で、耳の周りで、または耳の後ろでぴたりと合う(fit)サイズおよび形状のハウジング、および
前記ハウジング内のフィルムであって、制御信号を受信し、前記患者の中枢神経系を刺激して前記患者の望ましくない睡眠行動を十分に中断するようになおかつ前記患者の睡眠状態を有意に変えることを避けるように構成された触覚性で可聴な感覚を、受信した前記制御信号に応答して前記患者に提供するように構成されたフィルム、
を備える、アジテーター装置。 - 前記フィルムは、コイル状または巻物状のポリフッ化ビニリデン(PVDF)フィルムを含む、
請求項1に記載のアジテーター装置。 - 前記PVDFフィルムは、直列または並列のバイモルフ構造のうちの少なくとも一方を有する金属化PVDFフィルムを含む、
請求項2に記載のアジテーター装置。 - 前記ハウジングは、前記耳の中でぴたりと合うように構成される、
請求項1から3のいずれか一項に記載のアジテーター装置。 - 前記制御信号は、前記制御信号の瞬間的な電圧極性に従う前記フィルムの拡大および収縮を制御し、触覚性で可聴な前記感覚を提供する振動を前記フィルムにさせるように構成された交流電流(AC)励起電圧制御信号を含む、
請求項1から4のいずれか一項に記載のアジテーター装置。 - 前記制御信号の周波数は、触覚性で可聴な前記感覚の望まれる有効性を提供するために前記フィルムの共振周波数に実質的に一致するように構成される、
請求項5に記載のアジテーター装置。 - 前記制御信号の前記周波数は、1Hzと100Hzとの間の周波数を含む、
請求項6に記載のアジテーター装置。 - 睡眠障害を患う患者の中枢神経系を刺激するためのシステムであって、
前記患者から睡眠情報を受信するように構成された睡眠センサと、
アジテーターであって、
前記患者の耳の中で、耳に触れた状態で、耳の周りで、または耳の後ろでぴたりと合うサイズおよび形状のハウジング、および
前記ハウジング内のフィルムであって、前記患者の中枢神経系を刺激するように構成された触覚性で可聴な感覚を前記患者に提供するように構成されたフィルム、を含むアジテーター、および
前記睡眠センサから睡眠情報を受信し、受信した前記睡眠情報を用いて前記アジテーターのための制御信号を作成し、かつ、前記患者の望ましくない睡眠行動を十分に中断するためになおかつ前記患者の睡眠状態を有意に変えることを避けるために前期アジテーターの触覚性で可聴な前記感覚を制御するように構成された前記制御信号を前記アジテーターに提供するように構成されたコントローラ、
を備える、システム。 - 前記睡眠センサは、前記患者から呼吸情報を受信するように構成された呼吸センサを含む、
請求項8に記載のシステム。 - 前記睡眠センサは、前記患者の睡眠状態を示す情報を受信するように構成された睡眠状態センサを含む、
請求項8または9に記載のシステム。 - 前記フィルムは、直列バイモルフ構造および並列バイモルフ構造のうちの少なくとも一方を有するコイル状または巻物状の金属化ポリフッ化ビニリデン(PVDF)フィルムを含む、
請求項8から10のいずれか一項に記載のシステム。 - 前記ハウジングは、粘着剤を用いて前記耳の後ろに付けられるように構成される、
請求項8から11のいずれか一項に記載のシステム。 - 前記コントローラは、前記制御信号の瞬間的な電圧極性に従う前記フィルムの拡大および収縮を制御し触覚性で可聴な前記感覚を提供する振動を前記フィルムにさせる交流電流(AC)励起電圧制御信号を作成するように構成され、かつ、前記AC励起電圧制御信号の前記周波数は、触覚性で可聴な前記感覚の望まれる有効性を提供するために前記フィルムの共振周波数に実質的に一致するように構成される、
請求項8から12のいずれか一項に記載のシステム。 - 睡眠障害を患う患者の中枢神経系を刺激するための方法であって、
コントローラから制御信号を受信すること、および
前記患者の中枢神経系を刺激して前記患者の望ましくない睡眠行動を十分に中断するようになおかつ前記患者の睡眠状態を有意に変えることを避けるように構成された触覚性で可聴な感覚を、コイル状または巻物状のフィルムを用いかつ受信した前記制御信号に応答して前記患者に提供すること、
を備える、方法。 - 呼吸センサからの患者の呼吸情報および睡眠状態センサからの前記患者の睡眠状態を示す情報のうちの少なくとも一方を含む睡眠情報を前記患者から受信すること、および
受信した前記睡眠情報を用いて前記制御信号を作成すること、
を含む、請求項14に記載の方法。 - 前記患者からの前記睡眠情報の前記受信は、前記患者の前記呼吸情報を前記呼吸センサから受信することを含む、
請求項15に記載の方法。 - 触覚性で可聴な前記感覚の前記患者への前記コイル状または巻物状のフィルムを用いた前記提供は、直列バイモルフ構造および並列バイモルフ構造のうちの少なくとも一方を有する金属化ポリフッ化ビニリデン(PVDF)フィルムの使用を含む、
請求項14から16のいずれか一項に記載の方法。 - 前記患者の耳の中で、耳に触れた状態で、耳の周りで、または耳の後ろでぴたりと合うサイズおよび形状であり、かつ前記コイル状または巻物状のフィルムを含むハウジングを提供することを含む、
請求項14から17のいずれか一項に記載の方法。 - 前記制御信号の瞬間的な電圧極性に従う前記コイル状または巻物状のフィルムの拡大および収縮を制御するための交流電流(AC)励起電圧制御信号を作成することを含む、
請求項14から18のいずれか一項に記載の方法。 - 前記AC励起電圧制御信号の前記作成は、提供される触覚性で可聴な前記感覚の望まれる有効性を提供するために前記コイル状または巻物状のフィルムの共振周波数に実質的に一致するように構成された周波数での作成を含む、
請求項19に記載の方法。
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US4980208P | 2008-05-02 | 2008-05-02 | |
US61/049,802 | 2008-05-02 | ||
PCT/US2009/002705 WO2009134434A1 (en) | 2008-05-02 | 2009-05-01 | Agitator to stimulate the central nervous system |
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JP2011523566A true JP2011523566A (ja) | 2011-08-18 |
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JP2011507465A Pending JP2011523566A (ja) | 2008-05-02 | 2009-05-01 | 中枢神経系を刺激するためのアジテーター |
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US (1) | US8579794B2 (ja) |
EP (1) | EP2313036A1 (ja) |
JP (1) | JP2011523566A (ja) |
CA (1) | CA2727355A1 (ja) |
WO (1) | WO2009134434A1 (ja) |
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Also Published As
Publication number | Publication date |
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WO2009134434A1 (en) | 2009-11-05 |
US8579794B2 (en) | 2013-11-12 |
US20090287265A1 (en) | 2009-11-19 |
CA2727355A1 (en) | 2009-11-05 |
EP2313036A1 (en) | 2011-04-27 |
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