JP2011522795A5 - - Google Patents
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- Publication number
- JP2011522795A5 JP2011522795A5 JP2011508582A JP2011508582A JP2011522795A5 JP 2011522795 A5 JP2011522795 A5 JP 2011522795A5 JP 2011508582 A JP2011508582 A JP 2011508582A JP 2011508582 A JP2011508582 A JP 2011508582A JP 2011522795 A5 JP2011522795 A5 JP 2011522795A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- molecule
- composition according
- region
- ctla4
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5033608P | 2008-05-05 | 2008-05-05 | |
| US61/050,336 | 2008-05-05 | ||
| US12/387,359 US7915222B2 (en) | 2008-05-05 | 2009-05-01 | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
| US12/387,359 | 2009-05-01 | ||
| PCT/US2009/042761 WO2009137424A1 (en) | 2008-05-05 | 2009-05-05 | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011522795A JP2011522795A (ja) | 2011-08-04 |
| JP2011522795A5 true JP2011522795A5 (enExample) | 2012-03-15 |
Family
ID=41264941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011508582A Pending JP2011522795A (ja) | 2008-05-05 | 2009-05-05 | 未分類関節炎を有する対象における関節リウマチの発症を予防するための方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US7915222B2 (enExample) |
| EP (2) | EP2891665A1 (enExample) |
| JP (1) | JP2011522795A (enExample) |
| KR (1) | KR20110014180A (enExample) |
| CN (1) | CN102037010A (enExample) |
| AR (1) | AR071672A1 (enExample) |
| AU (1) | AU2009244448B2 (enExample) |
| BR (1) | BRPI0912249A2 (enExample) |
| CA (1) | CA2723698C (enExample) |
| CL (1) | CL2009001082A1 (enExample) |
| DK (1) | DK2279206T3 (enExample) |
| EA (1) | EA201001749A1 (enExample) |
| ES (1) | ES2539840T3 (enExample) |
| HK (1) | HK1208230A1 (enExample) |
| HR (1) | HRP20150552T1 (enExample) |
| HU (1) | HUE025256T2 (enExample) |
| IL (1) | IL208691A (enExample) |
| MX (1) | MX2010011503A (enExample) |
| NZ (1) | NZ589020A (enExample) |
| PL (1) | PL2279206T3 (enExample) |
| PT (1) | PT2279206E (enExample) |
| SI (1) | SI2279206T1 (enExample) |
| TW (2) | TWI454278B (enExample) |
| WO (1) | WO2009137424A1 (enExample) |
| ZA (1) | ZA201007914B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040022787A1 (en) * | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| US7915222B2 (en) * | 2008-05-05 | 2011-03-29 | Bristol-Myers Squibb Company | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
| JP6239517B2 (ja) * | 2011-10-10 | 2017-11-29 | メディミューン リミテッド | 関節リウマチの治療法 |
| US20140006055A1 (en) * | 2012-06-27 | 2014-01-02 | Iagnosis, Inc. | Integrated Medical Evaluation and Record Keeping System |
| US20150232558A1 (en) * | 2012-10-30 | 2015-08-20 | Emory University | Stimulating bone formation by inhibition of cd28 co-stimulation |
| WO2014151230A2 (en) * | 2013-03-15 | 2014-09-25 | Bristol-Myers Squibb Company | Method of treating granulomatosis with polyangiitis |
| US20170042972A1 (en) * | 2014-04-25 | 2017-02-16 | Chetan KARYEKAR | Use of ctla4 compound for achieving drug-free remission in subjects with early ra |
| EP3283508B1 (en) | 2015-04-17 | 2021-03-17 | Alpine Immune Sciences, Inc. | Immunomodulatory proteins with tunable affinities |
| JP7749319B2 (ja) | 2017-10-10 | 2025-10-06 | アルパイン イミューン サイエンシズ インコーポレイテッド | Ｃｔｌａ－４変異型免疫調節タンパク質およびそれらの使用 |
| BR112020013236A2 (pt) | 2018-01-03 | 2020-12-01 | Alpine Immune Sciences, Inc. | proteínas imunomoduladoras de múltiplos domínios e métodos de seu uso |
| CN110148465B (zh) * | 2019-05-10 | 2023-07-04 | 中山大学孙逸仙纪念医院 | 一种用于分析类风湿性关节炎的系统 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6641809B1 (en) | 1990-03-26 | 2003-11-04 | Bristol-Myers Squibb Company | Method of regulating cellular processes mediated by B7 and CD28 |
| US7070776B1 (en) | 1990-03-26 | 2006-07-04 | Bristol-Myers Squibb Company | Methods for blocking binding of CD28 receptor to B7 |
| US5770197A (en) | 1991-06-27 | 1998-06-23 | Bristol-Myers Squibb Company | Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules |
| US6090914A (en) | 1991-06-27 | 2000-07-18 | Bristol-Myers Squibb Company | CTLA4/CD28Ig hybrid fusion proteins and uses thereof |
| US5844095A (en) | 1991-06-27 | 1998-12-01 | Bristol-Myers Squibb Company | CTLA4 Ig fusion proteins |
| US5851795A (en) | 1991-06-27 | 1998-12-22 | Bristol-Myers Squibb Company | Soluble CTLA4 molecules and uses thereof |
| KR100238712B1 (ko) | 1991-06-27 | 2000-01-15 | 스티븐 비. 데이비스 | 씨티엘에이4 수용체,그를 함유한 연합단백질 및 그의 용도 |
| BR9405664A (pt) * | 1993-01-21 | 1996-04-30 | Univ Georgia | Composto imunogenio processos para evitar a toxicose por festuca em um herbivoro para tratar a toxicose por festuca em um herbivoro anticorpo purificado lingagem de célula de hidridoma e anticorpo |
| US5773253A (en) | 1993-01-22 | 1998-06-30 | Bristol-Myers Squibb Company | MYPPPY variants of CTL A4 and uses thereof |
| US6750334B1 (en) * | 1996-02-02 | 2004-06-15 | Repligen Corporation | CTLA4-immunoglobulin fusion proteins having modified effector functions and uses therefor |
| PT892643E (pt) | 1996-03-20 | 2002-09-30 | Univ Emory | Metodos para inibir uma resposta imunitaria bloqueando os circuitos de gp39/cd40 e ctla4/cd28/b7 e composicoes utilizaveis para o efeito |
| ZA98533B (en) | 1997-01-31 | 1999-07-22 | Bristol Myers Squibb Co | Soluble CTLA4 mutant molecules and uses thereof. |
| US20030219863A1 (en) | 1997-01-31 | 2003-11-27 | Bristol-Myers Squibb Company | Soluble CTLA4 mutant molecules and uses thereof |
| US7094874B2 (en) | 2000-05-26 | 2006-08-22 | Bristol-Myers Squibb Co. | Soluble CTLA4 mutant molecules |
| KR20030007899A (ko) | 2000-06-09 | 2003-01-23 | 브리스톨-마이어스스퀴브컴파니 | 림프구성 신호의 차단 및 ｌｆａ-1 매개 접착의 차단을통한 세포-매개 면역 반응의 조절 방법 |
| US20040022787A1 (en) | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| HRP20030071B1 (hr) * | 2000-07-03 | 2014-01-03 | Bristol-Myers Squibb Company | Postupci za lijeäśenje reumatskih bolesti uporabom topljivih ctla4 mutantnih molekula |
| CA2436139A1 (en) | 2001-01-26 | 2002-08-01 | Emory University | Methods of inducing organ transplant tolerance and correcting hemoglobinopathies |
| MXPA03010568A (es) | 2001-05-23 | 2005-03-07 | Squibb Bristol Myers Co | Metodos para proteger trasplantes alogenicos de celulas de isletas usando moleculas mutantes ctla4 solubles. |
| JP4541157B2 (ja) | 2002-12-23 | 2010-09-08 | ブリストル−マイヤーズ スクイブ カンパニー | タンパク質を製造するための哺乳類細胞培養法 |
| DE60335024D1 (de) | 2002-12-23 | 2010-12-30 | Bristol Myers Squibb Co | Produktqualitätsverbesserung in säugerzellkulturverfahrenzur proteinproduktion |
| AU2004264901B2 (en) | 2003-08-04 | 2009-12-10 | Bristol-Myers Squibb Company | Methods for treating cardiovascular disease using a soluble CTLA4 molecule |
| KR101280096B1 (ko) | 2005-06-29 | 2013-06-28 | 컴퓨메딕스 리미티드 | 전도성 브리지를 포함하는 센서 어셈블리 |
| CA2619429A1 (en) * | 2005-08-22 | 2007-03-01 | Incept, Llc | Flared stents and apparatus and methods for making and using them |
| AU2006330922B2 (en) | 2005-12-20 | 2012-07-26 | Bristol-Myers Squibb Company | Compositions and methods for producing a composition |
| TW200738261A (en) | 2005-12-20 | 2007-10-16 | Bristol Myers Squibb Co | Stable protein formulations |
| US7528111B2 (en) | 2006-05-12 | 2009-05-05 | Bristol-Myers Squibb Company | Method of vaccinating subjects receiving immune modulating therapy |
| US7915222B2 (en) * | 2008-05-05 | 2011-03-29 | Bristol-Myers Squibb Company | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
-
2009
- 2009-05-01 US US12/387,359 patent/US7915222B2/en active Active
- 2009-05-05 KR KR1020107027221A patent/KR20110014180A/ko not_active Ceased
- 2009-05-05 NZ NZ589020A patent/NZ589020A/en not_active IP Right Cessation
- 2009-05-05 HR HRP20150552TT patent/HRP20150552T1/hr unknown
- 2009-05-05 CA CA2723698A patent/CA2723698C/en active Active
- 2009-05-05 EP EP15152246.3A patent/EP2891665A1/en not_active Withdrawn
- 2009-05-05 PL PL09743410T patent/PL2279206T3/pl unknown
- 2009-05-05 HU HUE09743410A patent/HUE025256T2/en unknown
- 2009-05-05 EP EP20090743410 patent/EP2279206B1/en active Active
- 2009-05-05 AR ARP090101621A patent/AR071672A1/es unknown
- 2009-05-05 CN CN2009801162049A patent/CN102037010A/zh active Pending
- 2009-05-05 DK DK09743410.4T patent/DK2279206T3/en active
- 2009-05-05 WO PCT/US2009/042761 patent/WO2009137424A1/en not_active Ceased
- 2009-05-05 EA EA201001749A patent/EA201001749A1/ru unknown
- 2009-05-05 BR BRPI0912249A patent/BRPI0912249A2/pt not_active Application Discontinuation
- 2009-05-05 TW TW098114831A patent/TWI454278B/zh not_active IP Right Cessation
- 2009-05-05 PT PT97434104T patent/PT2279206E/pt unknown
- 2009-05-05 ES ES09743410.4T patent/ES2539840T3/es active Active
- 2009-05-05 MX MX2010011503A patent/MX2010011503A/es active IP Right Grant
- 2009-05-05 SI SI200931228T patent/SI2279206T1/sl unknown
- 2009-05-05 AU AU2009244448A patent/AU2009244448B2/en not_active Ceased
- 2009-05-05 JP JP2011508582A patent/JP2011522795A/ja active Pending
- 2009-05-05 TW TW103129409A patent/TW201444575A/zh unknown
- 2009-05-05 CL CL2009001082A patent/CL2009001082A1/es unknown
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2010
- 2010-10-13 IL IL208691A patent/IL208691A/en not_active IP Right Cessation
- 2010-11-04 ZA ZA2010/07914A patent/ZA201007914B/en unknown
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2011
- 2011-02-10 US US13/024,601 patent/US8435952B2/en active Active
- 2011-03-07 HK HK15108768.6A patent/HK1208230A1/en unknown
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2013
- 2013-03-27 US US13/851,166 patent/US9012408B2/en active Active