JP2011522276A - 無担体９９Ｍｏの製造プロセス - Google Patents
無担体９９Ｍｏの製造プロセス Download PDFInfo
- Publication number
- JP2011522276A JP2011522276A JP2011512400A JP2011512400A JP2011522276A JP 2011522276 A JP2011522276 A JP 2011522276A JP 2011512400 A JP2011512400 A JP 2011512400A JP 2011512400 A JP2011512400 A JP 2011512400A JP 2011522276 A JP2011522276 A JP 2011522276A
- Authority
- JP
- Japan
- Prior art keywords
- liquid
- compound
- molybdenum
- transferred
- process according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title abstract description 16
- 150000001875 compounds Chemical class 0.000 claims abstract description 34
- 230000000694 effects Effects 0.000 claims abstract description 19
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims abstract description 18
- 238000000034 method Methods 0.000 claims description 28
- 239000007788 liquid Substances 0.000 claims description 27
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims description 22
- 239000008346 aqueous phase Substances 0.000 claims description 8
- 239000007791 liquid phase Substances 0.000 claims description 7
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 claims description 5
- 239000005695 Ammonium acetate Substances 0.000 claims description 5
- 229940043376 ammonium acetate Drugs 0.000 claims description 5
- 235000019257 ammonium acetate Nutrition 0.000 claims description 5
- 239000000872 buffer Substances 0.000 claims description 3
- 230000004992 fission Effects 0.000 abstract description 15
- 230000003213 activating effect Effects 0.000 abstract description 2
- 239000000843 powder Substances 0.000 description 12
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 9
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 9
- 229910052750 molybdenum Inorganic materials 0.000 description 9
- 239000011733 molybdenum Substances 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 238000013459 approach Methods 0.000 description 5
- 238000000638 solvent extraction Methods 0.000 description 5
- 239000007853 buffer solution Substances 0.000 description 4
- PBAYDYUZOSNJGU-UHFFFAOYSA-N chelidonic acid Natural products OC(=O)C1=CC(=O)C=C(C(O)=O)O1 PBAYDYUZOSNJGU-UHFFFAOYSA-N 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 239000003758 nuclear fuel Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000000539 dimer Substances 0.000 description 3
- 238000000622 liquid--liquid extraction Methods 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 239000011550 stock solution Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 239000012901 Milli-Q water Substances 0.000 description 2
- 239000003929 acidic solution Substances 0.000 description 2
- 239000012670 alkaline solution Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000009616 inductively coupled plasma Methods 0.000 description 2
- 238000002354 inductively-coupled plasma atomic emission spectroscopy Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000005078 molybdenum compound Substances 0.000 description 2
- 150000002752 molybdenum compounds Chemical class 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000012074 organic phase Substances 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000012086 standard solution Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- WJBLZBSMZTYOQH-UHFFFAOYSA-N C(CC)C1(C=CC=C1)[Mo] Chemical compound C(CC)C1(C=CC=C1)[Mo] WJBLZBSMZTYOQH-UHFFFAOYSA-N 0.000 description 1
- CSKSYFFRZCALAP-UHFFFAOYSA-N C1(C=CC=C1)[Mo+] Chemical compound C1(C=CC=C1)[Mo+] CSKSYFFRZCALAP-UHFFFAOYSA-N 0.000 description 1
- MGFNVRAUSFQKFO-UHFFFAOYSA-N CC1=CC=CC1[Mo] Chemical compound CC1=CC=CC1[Mo] MGFNVRAUSFQKFO-UHFFFAOYSA-N 0.000 description 1
- 229910016006 MoSi Inorganic materials 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- VWVZEGJTBQPYID-UHFFFAOYSA-N [K+].[Mo+6] Chemical compound [K+].[Mo+6] VWVZEGJTBQPYID-UHFFFAOYSA-N 0.000 description 1
- 125000005595 acetylacetonate group Chemical group 0.000 description 1
- 229910052768 actinide Inorganic materials 0.000 description 1
- 150000001255 actinides Chemical class 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 235000011114 ammonium hydroxide Nutrition 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000000137 annealing Methods 0.000 description 1
- QZPSXPBJTPJTSZ-UHFFFAOYSA-N aqua regia Chemical compound Cl.O[N+]([O-])=O QZPSXPBJTPJTSZ-UHFFFAOYSA-N 0.000 description 1
- 238000010420 art technique Methods 0.000 description 1
- 238000001636 atomic emission spectroscopy Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- YXTPWUNVHCYOSP-UHFFFAOYSA-N bis($l^{2}-silanylidene)molybdenum Chemical compound [Si]=[Mo]=[Si] YXTPWUNVHCYOSP-UHFFFAOYSA-N 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000002144 chemical decomposition reaction Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011067 equilibration Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000005251 gamma ray Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910021343 molybdenum disilicide Inorganic materials 0.000 description 1
- CWQXQMHSOZUFJS-UHFFFAOYSA-N molybdenum disulfide Chemical compound S=[Mo]=S CWQXQMHSOZUFJS-UHFFFAOYSA-N 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/06—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by neutron irradiation
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/001—Recovery of specific isotopes from irradiated targets
- G21G2001/0036—Molybdenum
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Manufacture And Refinement Of Metals (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08157758.7 | 2008-06-06 | ||
| EP08157758A EP2131369A1 (en) | 2008-06-06 | 2008-06-06 | A process for the production of no-carrier added 99Mo |
| PCT/NL2009/050301 WO2009148306A1 (en) | 2008-06-06 | 2009-06-02 | A process for the production of no-carrier added 99mo |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011522276A true JP2011522276A (ja) | 2011-07-28 |
| JP2011522276A5 JP2011522276A5 (enExample) | 2012-06-28 |
Family
ID=39870009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011512400A Pending JP2011522276A (ja) | 2008-06-06 | 2009-06-02 | 無担体９９Ｍｏの製造プロセス |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110118491A1 (enExample) |
| EP (2) | EP2131369A1 (enExample) |
| JP (1) | JP2011522276A (enExample) |
| CN (1) | CN102113059A (enExample) |
| AU (1) | AU2009255830A1 (enExample) |
| BR (1) | BRPI0914861A2 (enExample) |
| CA (1) | CA2727156A1 (enExample) |
| RU (1) | RU2010154094A (enExample) |
| WO (1) | WO2009148306A1 (enExample) |
| ZA (1) | ZA201009139B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017537321A (ja) * | 2014-11-25 | 2017-12-14 | テクニシェ ユニヴェルシテイト デルフト | 柔軟な照射設備 |
| JP2021071435A (ja) * | 2019-11-01 | 2021-05-06 | 株式会社タカハシＲｉラボ | テクネチウム９９ｍ製造システム及びテクネチウム９９ｍ製造方法 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9177679B2 (en) * | 2010-02-11 | 2015-11-03 | Uchicago Argonne, Llc | Accelerator-based method of producing isotopes |
| US10332646B2 (en) * | 2011-12-05 | 2019-06-25 | Wisconsin Alumni Research Foundation | Apparatus and method for generating medical isotopes |
| PL3629342T3 (pl) * | 2014-08-06 | 2021-12-20 | Research Triangle Institute | Wysokowydajne wytwarzanie produktów wychwytu neutronów |
| US10930407B2 (en) * | 2014-11-21 | 2021-02-23 | Gary M. Sandquist | Productions of radioisotopes |
| US10804000B2 (en) | 2016-05-18 | 2020-10-13 | The Regents Of The University Of California | High efficiency continuous-flow production of radioisotopes |
| CN106297910B (zh) * | 2016-09-14 | 2018-01-30 | 厦门大学 | 一种核反应堆灰控制棒用钼基氧化铽材料及其应用 |
| CN111785407B (zh) * | 2020-07-13 | 2022-08-16 | 中国科学院上海应用物理研究所 | 一种含钼的物质的处理方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008047946A1 (en) * | 2006-10-20 | 2008-04-24 | Japan Atomic Energy Agency | Process for producing radioactive molybdenum, apparatus therefor and radioactive molybdenum produced by the process |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85109328B (zh) * | 1985-12-26 | 1986-11-05 | 中国原子能科学研究院 | 从铀-235及其裂变产物中分离医用钼-99的方法 |
| SK286044B6 (sk) * | 1997-06-19 | 2008-01-07 | European Organization For Nuclear Research | Spôsob exponovania materiálu, spôsob produkovaniaužitočného izotopu a spôsob transmutácie zahrnujúci spôsob exponovania |
| CN1098723C (zh) * | 1999-05-25 | 2003-01-15 | 中国核动力研究设计院 | 用医用同位素生产堆生产钼－99的提取与纯化工艺 |
| JP4231779B2 (ja) * | 2001-06-05 | 2009-03-04 | 日本メジフィジックス株式会社 | ターゲット処理 |
| US6998052B2 (en) * | 2002-04-12 | 2006-02-14 | Pg Research Foundation | Multicolumn selectivity inversion generator for production of ultrapure radionuclides |
| WO2003086569A1 (en) * | 2002-04-12 | 2003-10-23 | Pg Research Foundation | Multicolumn selectivity inversion generator for production of ultrapure radionuclides |
| US20060023829A1 (en) * | 2004-08-02 | 2006-02-02 | Battelle Memorial Institute | Medical radioisotopes and methods for producing the same |
| US20080187489A1 (en) * | 2004-10-12 | 2008-08-07 | Mcmaster University | Generator and Method for Production of Technetium-99m |
-
2008
- 2008-06-06 EP EP08157758A patent/EP2131369A1/en not_active Withdrawn
-
2009
- 2009-06-02 AU AU2009255830A patent/AU2009255830A1/en not_active Abandoned
- 2009-06-02 EP EP09758553A patent/EP2301041A1/en not_active Withdrawn
- 2009-06-02 JP JP2011512400A patent/JP2011522276A/ja active Pending
- 2009-06-02 CN CN2009801303865A patent/CN102113059A/zh active Pending
- 2009-06-02 WO PCT/NL2009/050301 patent/WO2009148306A1/en not_active Ceased
- 2009-06-02 RU RU2010154094/07A patent/RU2010154094A/ru not_active Application Discontinuation
- 2009-06-02 CA CA2727156A patent/CA2727156A1/en not_active Abandoned
- 2009-06-02 BR BRPI0914861A patent/BRPI0914861A2/pt not_active IP Right Cessation
- 2009-06-02 US US12/996,209 patent/US20110118491A1/en not_active Abandoned
-
2010
- 2010-12-20 ZA ZA2010/09139A patent/ZA201009139B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008047946A1 (en) * | 2006-10-20 | 2008-04-24 | Japan Atomic Energy Agency | Process for producing radioactive molybdenum, apparatus therefor and radioactive molybdenum produced by the process |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017537321A (ja) * | 2014-11-25 | 2017-12-14 | テクニシェ ユニヴェルシテイト デルフト | 柔軟な照射設備 |
| JP2021071435A (ja) * | 2019-11-01 | 2021-05-06 | 株式会社タカハシＲｉラボ | テクネチウム９９ｍ製造システム及びテクネチウム９９ｍ製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201009139B (en) | 2012-07-25 |
| RU2010154094A (ru) | 2012-07-20 |
| WO2009148306A1 (en) | 2009-12-10 |
| US20110118491A1 (en) | 2011-05-19 |
| AU2009255830A1 (en) | 2009-12-10 |
| CA2727156A1 (en) | 2009-12-10 |
| EP2131369A1 (en) | 2009-12-09 |
| CN102113059A (zh) | 2011-06-29 |
| BRPI0914861A2 (pt) | 2015-11-03 |
| EP2301041A1 (en) | 2011-03-30 |
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