JP2011520916A5 - - Google Patents
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- JP2011520916A5 JP2011520916A5 JP2011509763A JP2011509763A JP2011520916A5 JP 2011520916 A5 JP2011520916 A5 JP 2011520916A5 JP 2011509763 A JP2011509763 A JP 2011509763A JP 2011509763 A JP2011509763 A JP 2011509763A JP 2011520916 A5 JP2011520916 A5 JP 2011520916A5
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- pharmaceutical composition
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- 239000008194 pharmaceutical composition Substances 0.000 claims 15
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 230000007774 longterm Effects 0.000 claims 4
- 206010039085 Rhinitis allergic Diseases 0.000 claims 2
- 201000010105 allergic rhinitis Diseases 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000174 Interleukin-10 Proteins 0.000 claims 1
- 108090000176 Interleukin-13 Proteins 0.000 claims 1
- 108090000978 Interleukin-4 Proteins 0.000 claims 1
- 108010002616 Interleukin-5 Proteins 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000003979 eosinophil Anatomy 0.000 claims 1
- 230000002519 immonomodulatory effect Effects 0.000 claims 1
- 230000009545 invasion Effects 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5360508P | 2008-05-15 | 2008-05-15 | |
| US61/053,605 | 2008-05-15 | ||
| PCT/US2009/044192 WO2009140626A2 (en) | 2008-05-15 | 2009-05-15 | Long term disease modification using immunostimulatory oligonucleotides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520916A JP2011520916A (ja) | 2011-07-21 |
| JP2011520916A5 true JP2011520916A5 (https=) | 2012-06-28 |
| JP5727367B2 JP5727367B2 (ja) | 2015-06-03 |
Family
ID=41258402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011509763A Active JP5727367B2 (ja) | 2008-05-15 | 2009-05-15 | 免疫賦活オリゴヌクレオチドを使用する長期疾患改良 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8815817B2 (https=) |
| EP (1) | EP2300102B1 (https=) |
| JP (1) | JP5727367B2 (https=) |
| AU (1) | AU2009246169B2 (https=) |
| CA (1) | CA2724418A1 (https=) |
| WO (1) | WO2009140626A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2423335B1 (en) * | 2001-06-21 | 2014-05-14 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same |
| CN101171033A (zh) * | 2005-03-04 | 2008-04-30 | 戴纳瓦克斯技术公司 | 包含具免疫刺激序列iss之寡核苷酸的疫苗：其中iss与抗原缀合并通过缓冲条件和其他赋形剂稳定 |
| AU2009246169B2 (en) | 2008-05-15 | 2015-01-22 | Dynavax Technologies Corporation | Long term disease modification using immunostimulatory oligonucleotides |
| RU2612521C2 (ru) | 2009-07-06 | 2017-03-09 | Онтории, Инк. | Новые пролекарства нуклеиновых кислот и способы их применения |
| JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| MX374963B (es) | 2011-04-29 | 2025-03-06 | Selecta Biosciences Inc | Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos. |
| US10946568B2 (en) | 2011-06-09 | 2021-03-16 | Rimtec Corporation | Field joint coating material and a process for making a field joint |
| CN103796657B (zh) | 2011-07-19 | 2017-07-11 | 波涛生命科学有限公司 | 合成官能化核酸的方法 |
| JP5800263B2 (ja) * | 2011-09-27 | 2015-10-28 | 学校法人兵庫医科大学 | アレルギー性鼻炎治療剤のスクリーニング方法およびその利用 |
| PL2872485T3 (pl) | 2012-07-13 | 2021-05-31 | Wave Life Sciences Ltd. | Asymetryczna grupa pomocnicza |
| BR122020023215B1 (pt) | 2013-05-03 | 2022-11-22 | Selecta Biosciences, Inc | Composição e kit de nanocarreadores sintéticos tolerogênicos para reduzir ou prevenir anafilaxia em resposta a um antígeno não alergênico |
| US10322173B2 (en) * | 2014-01-15 | 2019-06-18 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| JP7242180B2 (ja) | 2014-09-07 | 2023-03-20 | セレクタ バイオサイエンシーズ インコーポレーテッド | 抗ウイルス導入ベクター免疫応答を減弱化するための方法および組成物 |
| WO2018039465A1 (en) * | 2016-08-25 | 2018-03-01 | Selecta Biosciences, Inc. | Polyester polymer matrices for the delivery of allergens |
| ES3036482T3 (en) | 2017-03-11 | 2025-09-19 | Cartesian Therapeutics Inc | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| AU2020287627A1 (en) | 2019-06-04 | 2021-11-18 | Selecta Biosciences, Inc. | Formulations and doses of PEGylated uricase |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4948882A (en) | 1983-02-22 | 1990-08-14 | Syngene, Inc. | Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |
| US4650675A (en) | 1983-08-18 | 1987-03-17 | The Children's Medical Center Corporation | Oligonucleotide conjugates |
| US5015733A (en) | 1983-12-20 | 1991-05-14 | California Institute Of Technology | Nucleosides possessing blocked aliphatic amino groups |
| US5118800A (en) | 1983-12-20 | 1992-06-02 | California Institute Of Technology | Oligonucleotides possessing a primary amino group in the terminal nucleotide |
| US4849513A (en) | 1983-12-20 | 1989-07-18 | California Institute Of Technology | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups |
| US5118802A (en) | 1983-12-20 | 1992-06-02 | California Institute Of Technology | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside |
| US4910300A (en) | 1985-12-11 | 1990-03-20 | Chiron Corporation | Method for making nucleic acid probes |
| US5093232A (en) | 1985-12-11 | 1992-03-03 | Chiron Corporation | Nucleic acid probes |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5278302A (en) | 1988-05-26 | 1994-01-11 | University Patents, Inc. | Polynucleotide phosphorodithioates |
| US5391723A (en) | 1989-05-31 | 1995-02-21 | Neorx Corporation | Oligonucleotide conjugates |
| US5552391A (en) | 1990-01-16 | 1996-09-03 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| US5460831A (en) | 1990-06-22 | 1995-10-24 | The Regents Of The University Of California | Targeted transfection nanoparticles |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| EP1167379A3 (en) | 1994-07-15 | 2004-09-08 | University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| CA2244946C (en) | 1996-01-30 | 2010-04-13 | The Regents Of The University Of California | Gene expression vectors which generate an antigen specific immune response and methods of using the same |
| ATE292980T1 (de) | 1996-10-11 | 2005-04-15 | Univ California | Immunostimulierende oligonucleotidekonjugate |
| EP1003850B1 (en) | 1997-06-06 | 2009-05-27 | The Regents of the University of California | Inhibitors of dna immunostimulatory sequence activity |
| US6589940B1 (en) | 1997-06-06 | 2003-07-08 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| JP4663113B2 (ja) | 1997-09-05 | 2011-03-30 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 抗原刺激顆粒球媒介炎症を予防または軽減するための免疫刺激オリゴヌクレオチドの使用 |
| US6562798B1 (en) | 1998-06-05 | 2003-05-13 | Dynavax Technologies Corp. | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
| SE9901257D0 (sv) | 1999-04-09 | 1999-04-09 | Hel Ab | Behandling av smärta efter ledoperation |
| EP1176966B1 (en) | 1999-04-12 | 2013-04-03 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Oligodeoxynucleotide and its use to induce an immune response |
| US7585847B2 (en) | 2000-02-03 | 2009-09-08 | Coley Pharmaceutical Group, Inc. | Immunostimulatory nucleic acids for the treatment of asthma and allergy |
| US20010046967A1 (en) * | 2000-03-10 | 2001-11-29 | Gary Van Nest | Methods of preventing and treating respiratory viral infection using immunomodulatory polynucleotide |
| US20030129251A1 (en) * | 2000-03-10 | 2003-07-10 | Gary Van Nest | Biodegradable immunomodulatory formulations and methods for use thereof |
| US20040132677A1 (en) | 2001-06-21 | 2004-07-08 | Fearon Karen L. | Chimeric immunomodulatory compounds and methods of using the same-IV |
| DE10230693A1 (de) | 2002-07-06 | 2004-01-22 | BSH Bosch und Siemens Hausgeräte GmbH | Kühl-oder Gefriergerät |
| CN100471486C (zh) | 2002-08-12 | 2009-03-25 | 戴纳伐克斯技术股份有限公司 | 免疫调节组合物,其制备方法和使用方法 |
| JP5102959B2 (ja) | 2002-12-23 | 2012-12-19 | ダイナバックス テクノロジーズ コーポレイション | 免疫刺激配列オリゴヌクレオチド及びその使用方法 |
| CN101171033A (zh) * | 2005-03-04 | 2008-04-30 | 戴纳瓦克斯技术公司 | 包含具免疫刺激序列iss之寡核苷酸的疫苗：其中iss与抗原缀合并通过缓冲条件和其他赋形剂稳定 |
| AU2007333368C1 (en) | 2006-11-09 | 2014-03-13 | Dynavax Technologies Corporation | Long term disease modification using immunostimulatory oligonucleotides |
| CA2708942A1 (en) * | 2007-12-19 | 2009-06-25 | Mivac Development Aktiebolag | Compositions and methods for treatment of autoimmune and allergic diseases |
| AU2009246169B2 (en) * | 2008-05-15 | 2015-01-22 | Dynavax Technologies Corporation | Long term disease modification using immunostimulatory oligonucleotides |
-
2009
- 2009-05-15 AU AU2009246169A patent/AU2009246169B2/en not_active Ceased
- 2009-05-15 JP JP2011509763A patent/JP5727367B2/ja active Active
- 2009-05-15 US US12/992,590 patent/US8815817B2/en not_active Expired - Fee Related
- 2009-05-15 EP EP09747707.9A patent/EP2300102B1/en not_active Ceased
- 2009-05-15 CA CA2724418A patent/CA2724418A1/en not_active Abandoned
- 2009-05-15 WO PCT/US2009/044192 patent/WO2009140626A2/en not_active Ceased
-
2014
- 2014-07-18 US US14/335,790 patent/US9333254B2/en not_active Expired - Fee Related
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