JP2011516521A5 - - Google Patents
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- Publication number
- JP2011516521A5 JP2011516521A5 JP2011503429A JP2011503429A JP2011516521A5 JP 2011516521 A5 JP2011516521 A5 JP 2011516521A5 JP 2011503429 A JP2011503429 A JP 2011503429A JP 2011503429 A JP2011503429 A JP 2011503429A JP 2011516521 A5 JP2011516521 A5 JP 2011516521A5
- Authority
- JP
- Japan
- Prior art keywords
- allergen
- dosage form
- solid dosage
- administration
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013566 allergen Substances 0.000 claims 18
- 239000007909 solid dosage form Substances 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 7
- 230000001932 seasonal effect Effects 0.000 claims 6
- 239000013573 pollen allergen Substances 0.000 claims 3
- 239000003826 tablet Substances 0.000 claims 3
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 229940074608 allergen extract Drugs 0.000 claims 2
- 230000007815 allergy Effects 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000007891 compressed tablet Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000001508 eye Anatomy 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000013574 grass pollen allergen Substances 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 230000000877 morphologic effect Effects 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 210000000664 rectum Anatomy 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000001635 urinary tract Anatomy 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
- 239000002023 wood Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4440108P | 2008-04-11 | 2008-04-11 | |
| US61/044,401 | 2008-04-11 | ||
| DKPA200800533 | 2008-04-11 | ||
| DKPA200800533 | 2008-04-11 | ||
| PCT/EP2009/054186 WO2009124954A1 (en) | 2008-04-11 | 2009-04-08 | Mucosomal allergen-specific immunotherapy with initial dosing after start of pollen season |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187908A Division JP2015013891A (ja) | 2008-04-11 | 2014-09-16 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011516521A JP2011516521A (ja) | 2011-05-26 |
| JP2011516521A5 true JP2011516521A5 (https=) | 2012-05-31 |
| JP5618981B2 JP5618981B2 (ja) | 2014-11-05 |
Family
ID=39809974
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503429A Expired - Fee Related JP5618981B2 (ja) | 2008-04-11 | 2009-04-08 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
| JP2014187908A Pending JP2015013891A (ja) | 2008-04-11 | 2014-09-16 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187908A Pending JP2015013891A (ja) | 2008-04-11 | 2014-09-16 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9248097B2 (https=) |
| EP (1) | EP2265285B1 (https=) |
| JP (2) | JP5618981B2 (https=) |
| CN (1) | CN102014954A (https=) |
| AU (1) | AU2009235490B2 (https=) |
| BR (1) | BRPI0911433A2 (https=) |
| CA (1) | CA2720455A1 (https=) |
| DE (1) | DE202008006598U1 (https=) |
| EA (1) | EA019202B1 (https=) |
| ES (1) | ES2406391T3 (https=) |
| MX (1) | MX2010011012A (https=) |
| WO (1) | WO2009124954A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05005528A (es) * | 2002-11-26 | 2006-04-05 | Alk Abello As | Producto farmaceutico de alergeno. |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| DE202008006598U1 (de) * | 2008-04-11 | 2008-10-02 | Alk-Abelló A/S | Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung |
| KR20130118884A (ko) | 2010-10-15 | 2013-10-30 | 알크-아벨로 에이/에스 | 알레르겐 소스 물질로부터 유도된 무관련 알레르겐을 이용한 과민성 면역반응의 억제 |
| US20120100163A1 (en) * | 2010-10-15 | 2012-04-26 | Alk-Abello A/S | Suppression of a type 1 hypersensitivity immune response with an unrelated antigen |
| WO2012148549A1 (en) | 2011-02-25 | 2012-11-01 | Benaroya Research Institute | Detection of an immune response |
| JP2012240978A (ja) * | 2011-05-20 | 2012-12-10 | Nitto Denko Corp | 医薬組成物及びゼリー状製剤 |
| JP2012240975A (ja) * | 2011-05-20 | 2012-12-10 | Nitto Denko Corp | 医薬組成物及びゼリー状製剤 |
| SG11201402650RA (en) | 2012-01-16 | 2014-06-27 | Elizabeth Mckenna | Compositions and methods for the treatment of hepatic diseases and disorders |
| US12268718B2 (en) | 2012-01-16 | 2025-04-08 | Labyrinth Holdings Llc | Control of cellular redox levels |
| JP6306588B2 (ja) | 2012-08-21 | 2018-04-04 | サノフィ・バイオテクノロジー | Il−4rアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
| PL2892927T3 (pl) | 2012-09-07 | 2018-11-30 | Regeneron Pharmaceuticals, Inc. | Sposoby leczenia atopowego zapalenia skóry przez podawanie antagonisty IL-4R |
| BR112015006264A2 (pt) | 2012-09-21 | 2017-07-04 | Mckenna Elizabeth | composições de oligonucleotídeos cpg ocorrendo naturalmente e suas aplicações terapêuticas |
| TWI755763B (zh) | 2013-06-04 | 2022-02-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
| KR102695088B1 (ko) | 2014-02-28 | 2024-08-16 | 리제너론 파아마슈티컬스, 인크. | Il-4r 길항제의 투여에 의한 피부 감염의 치료 방법 |
| CA3246946A1 (en) | 2014-11-14 | 2025-11-29 | Sanofi Biotechnology | Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist |
| ES2994774T3 (en) | 2016-09-01 | 2025-01-31 | Regeneron Pharma | Methods for preventing or treating allergy by administering an il-4r antagonist |
| WO2018057776A1 (en) | 2016-09-22 | 2018-03-29 | Regeneron Pharmaceuticals, Inc. | Methods for treating severe atopic dermatitis by administering an il-4r inhibitor |
| TWI857389B (zh) | 2016-12-01 | 2024-10-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
| KR102694419B1 (ko) | 2017-10-30 | 2024-08-09 | 사노피 바이오테크놀로지 | Il-4r 길항제를 투여하여 천식을 치료 또는 예방하는 방법 |
| BR112020020387A2 (pt) | 2018-05-13 | 2021-01-19 | Regeneron Pharmaceuticals, Inc. | Métodos para o tratamento de dermatite atópica por administração de um inibidor de il-4r |
| CN113597328B (zh) | 2019-03-21 | 2025-10-31 | 瑞泽恩制药公司 | 用于治疗过敏症的il-4/il-13途径抑制剂和浆细胞消融的组合 |
| WO2021011614A1 (en) | 2019-07-16 | 2021-01-21 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an il-4r antagonist |
| JP7836754B2 (ja) | 2019-08-05 | 2026-03-27 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Il-4rアンタゴニストを投与することによりアレルギーを治療しアレルゲン特異的免疫療法を増強するための方法 |
| CN114173816A (zh) | 2019-08-05 | 2022-03-11 | 瑞泽恩制药公司 | 通过施用il-4r拮抗剂治疗特应性皮炎的方法 |
| EP4513185A1 (en) * | 2023-08-22 | 2025-02-26 | Luxembourg Institute of Health (LIH) | Early response biomarkers for allergen immunotherapy |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK137992D0 (da) | 1992-11-13 | 1992-11-13 | Alk Lab As | Fremgangsmaade til paavisning af et immunologisk aktivt stof i en proeve under anvendelse af et maerkningsstof |
| JPH0959179A (ja) * | 1995-08-28 | 1997-03-04 | Japan Tobacco Inc | スギ花粉症予防性を有する口腔衛生剤 |
| DK1062341T3 (da) | 1998-03-16 | 2008-11-03 | Alk Abello As | Muterede rekombinante allergener |
| FR2778244B1 (fr) | 1998-04-30 | 2000-07-13 | Univ Joseph Fourier | Procede d'excitation d'une cavite optique pour la detection de gaz a l'etat de traces |
| CN100577804C (zh) | 2000-11-16 | 2010-01-06 | 阿尔克-阿贝洛有限公司 | 新型变态反应原突变体 |
| CN1668737A (zh) | 2002-05-16 | 2005-09-14 | 阿尔克-阿贝洛有限公司 | 重组Bet.V.1过敏原突变体及其方法和制备 |
| MXPA05005528A (es) * | 2002-11-26 | 2006-04-05 | Alk Abello As | Producto farmaceutico de alergeno. |
| US8491909B2 (en) | 2004-02-06 | 2013-07-23 | Greer Laboratories, Inc. | Methods and compositions for dosing of allergens |
| JP2007524096A (ja) | 2004-02-26 | 2007-08-23 | アルカベロ アクチェセルスカプ | 粘膜投与用ワクチンの治療可能性の評価方法 |
| US20060115499A1 (en) | 2004-09-27 | 2006-06-01 | Alk-Abello A/S | Liquid allergy vaccine formulation for oromucosal administration |
| WO2006050729A2 (en) | 2004-11-10 | 2006-05-18 | Alk-Abellò A/S | Method of preventive treatment of allergy by mucosal administration of an allergy vaccine |
| PT1812059E (pt) * | 2004-11-10 | 2010-07-26 | Alk Abelle As | MéTODO DE TRATAMENTO PREVENTIVO DA ALERGIA POR ADMINISTRAÆO POR VIA MUCOSAL DE UMA VACINA PARA A ALERGIA |
| CN101098711A (zh) * | 2005-01-07 | 2008-01-02 | 阿尔克-阿贝洛有限公司 | 通过口粘膜施用变态反应疫苗预防性治疗变态反应的方法 |
| US20060210590A1 (en) * | 2005-02-03 | 2006-09-21 | Alk-Abello A/S | Minor allergen control to increase safety of immunotherapy |
| EP1933867A1 (en) | 2005-10-04 | 2008-06-25 | Alk-Abello A/S | Solid vaccine formulation |
| KR20080070851A (ko) | 2005-11-04 | 2008-07-31 | 알크-아벨로 에이/에스 | 구강점막 투여용 액상 알레르기 백신 제형의 용도 |
| DE202007004567U1 (de) | 2007-03-28 | 2007-10-11 | Alk-Abelló A/S | Verwendung einer adjuvierten Allergievakzinformulierung zur parenteralen Verabreichung |
| EP1974746B1 (en) * | 2007-03-28 | 2012-01-11 | Alk-Abelló A/S | Use of an adjuvanted allergy vaccine formulation for parenteral administration |
| DE202008006598U1 (de) * | 2008-04-11 | 2008-10-02 | Alk-Abelló A/S | Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung |
-
2008
- 2008-05-15 DE DE202008006598U patent/DE202008006598U1/de not_active Expired - Lifetime
-
2009
- 2009-04-08 EP EP09730293A patent/EP2265285B1/en not_active Revoked
- 2009-04-08 JP JP2011503429A patent/JP5618981B2/ja not_active Expired - Fee Related
- 2009-04-08 AU AU2009235490A patent/AU2009235490B2/en not_active Ceased
- 2009-04-08 EA EA201071182A patent/EA019202B1/ru not_active IP Right Cessation
- 2009-04-08 CA CA2720455A patent/CA2720455A1/en not_active Abandoned
- 2009-04-08 CN CN2009801154343A patent/CN102014954A/zh active Pending
- 2009-04-08 MX MX2010011012A patent/MX2010011012A/es active IP Right Grant
- 2009-04-08 ES ES09730293T patent/ES2406391T3/es active Active
- 2009-04-08 BR BRPI0911433A patent/BRPI0911433A2/pt not_active IP Right Cessation
- 2009-04-08 US US12/988,513 patent/US9248097B2/en active Active
- 2009-04-08 WO PCT/EP2009/054186 patent/WO2009124954A1/en not_active Ceased
-
2014
- 2014-01-10 US US14/152,753 patent/US20140127298A1/en not_active Abandoned
- 2014-09-16 JP JP2014187908A patent/JP2015013891A/ja active Pending
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