JP2011516521A5 - - Google Patents
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- Publication number
- JP2011516521A5 JP2011516521A5 JP2011503429A JP2011503429A JP2011516521A5 JP 2011516521 A5 JP2011516521 A5 JP 2011516521A5 JP 2011503429 A JP2011503429 A JP 2011503429A JP 2011503429 A JP2011503429 A JP 2011503429A JP 2011516521 A5 JP2011516521 A5 JP 2011516521A5
- Authority
- JP
- Japan
- Prior art keywords
- allergen
- dosage form
- solid dosage
- administration
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013566 allergen Substances 0.000 claims 18
- 239000007909 solid dosage form Substances 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 7
- 230000001932 seasonal effect Effects 0.000 claims 6
- 239000013573 pollen allergen Substances 0.000 claims 3
- 239000003826 tablet Substances 0.000 claims 3
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 229940074608 allergen extract Drugs 0.000 claims 2
- 230000007815 allergy Effects 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000007891 compressed tablet Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000001508 eye Anatomy 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000013574 grass pollen allergen Substances 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 230000000877 morphologic effect Effects 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 210000000664 rectum Anatomy 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000001635 urinary tract Anatomy 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
- 239000002023 wood Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4440108P | 2008-04-11 | 2008-04-11 | |
| DKPA200800533 | 2008-04-11 | ||
| DKPA200800533 | 2008-04-11 | ||
| US61/044,401 | 2008-04-11 | ||
| PCT/EP2009/054186 WO2009124954A1 (en) | 2008-04-11 | 2009-04-08 | Mucosomal allergen-specific immunotherapy with initial dosing after start of pollen season |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187908A Division JP2015013891A (ja) | 2008-04-11 | 2014-09-16 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011516521A JP2011516521A (ja) | 2011-05-26 |
| JP2011516521A5 true JP2011516521A5 (https=) | 2012-05-31 |
| JP5618981B2 JP5618981B2 (ja) | 2014-11-05 |
Family
ID=39809974
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503429A Expired - Fee Related JP5618981B2 (ja) | 2008-04-11 | 2009-04-08 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
| JP2014187908A Pending JP2015013891A (ja) | 2008-04-11 | 2014-09-16 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187908A Pending JP2015013891A (ja) | 2008-04-11 | 2014-09-16 | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9248097B2 (https=) |
| EP (1) | EP2265285B1 (https=) |
| JP (2) | JP5618981B2 (https=) |
| CN (1) | CN102014954A (https=) |
| AU (1) | AU2009235490B2 (https=) |
| BR (1) | BRPI0911433A2 (https=) |
| CA (1) | CA2720455A1 (https=) |
| DE (1) | DE202008006598U1 (https=) |
| EA (1) | EA019202B1 (https=) |
| ES (1) | ES2406391T3 (https=) |
| MX (1) | MX2010011012A (https=) |
| WO (1) | WO2009124954A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004047793A1 (en) * | 2002-11-26 | 2004-06-10 | Alk-Abelló A/S | Pharmaceutical allergen product |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| DE202008006598U1 (de) * | 2008-04-11 | 2008-10-02 | Alk-Abelló A/S | Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung |
| US20120100163A1 (en) * | 2010-10-15 | 2012-04-26 | Alk-Abello A/S | Suppression of a type 1 hypersensitivity immune response with an unrelated antigen |
| US20120100164A1 (en) | 2010-10-15 | 2012-04-26 | Alk-Abello A/S | Suppression of a hypersensitivity immune response with unrelated antigen derived from allergen source material |
| EP2681555B1 (en) | 2011-02-25 | 2020-04-08 | Benaroya Research Institute | Detection of an allergic disorder |
| JP2012240975A (ja) * | 2011-05-20 | 2012-12-10 | Nitto Denko Corp | 医薬組成物及びゼリー状製剤 |
| JP2012240978A (ja) * | 2011-05-20 | 2012-12-10 | Nitto Denko Corp | 医薬組成物及びゼリー状製剤 |
| US12268718B2 (en) | 2012-01-16 | 2025-04-08 | Labyrinth Holdings Llc | Control of cellular redox levels |
| CA3208225A1 (en) | 2012-01-16 | 2013-07-25 | Elizabeth Mckenna | Compositions and methods for the treatment of hepatitic diseases and disorders |
| US9574004B2 (en) | 2012-08-21 | 2017-02-21 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an IL-4R antagonist |
| PT3889181T (pt) | 2012-09-07 | 2024-05-29 | Regeneron Pharma | Um anticorpo antagonista de il-4r para utilização no tratamento da dermatite atópica por administração |
| JP2015535829A (ja) | 2012-09-21 | 2015-12-17 | マッケーナ、エリザベス | 天然に存在するＣｐＧオリゴヌクレオチド組成物およびその治療的適用 |
| TWI633891B (zh) | 2013-06-04 | 2018-09-01 | 再生元醫藥公司 | 藉由投與ｉｌ－４ｒ抑制劑以治療過敏及增強過敏原－特異之免疫療法的方法 |
| TWI682781B (zh) | 2013-07-11 | 2020-01-21 | 美商再生元醫藥公司 | 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法 |
| WO2015130975A1 (en) | 2014-02-28 | 2015-09-03 | Regeneron Pharmaceuticals, Inc. | Methods for treating skin infection by administering an il-4r antagonist |
| AU2015346150B2 (en) | 2014-11-14 | 2021-08-19 | Regeneron Pharmaceuticals, Inc. | Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist |
| HUE067888T2 (hu) | 2016-09-01 | 2024-11-28 | Regeneron Pharma | Módszerek az allergia megelõzésére vagy kezelésére egy IL-4R antagonista adagolásával |
| WO2018057776A1 (en) | 2016-09-22 | 2018-03-29 | Regeneron Pharmaceuticals, Inc. | Methods for treating severe atopic dermatitis by administering an il-4r inhibitor |
| TWI784988B (zh) | 2016-12-01 | 2022-12-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
| CA3079946A1 (en) | 2017-10-30 | 2019-05-09 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an il-4r antagonist |
| US11292847B2 (en) | 2018-05-13 | 2022-04-05 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an IL-4R inhibitor |
| CA3132587A1 (en) | 2019-03-21 | 2020-09-24 | Regeneron Pharmaceuticals, Inc. | Combination of il-4/il-13 pathway inhibitors and plasma cell ablation for treating allergy |
| BR112022000740A2 (pt) | 2019-07-16 | 2022-07-05 | Sanofi Biotechnology | Métodos para tratamento ou prevenção de asma por administração de um antagonista de il-4r |
| WO2021026205A1 (en) | 2019-08-05 | 2021-02-11 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r antagonist |
| US11504426B2 (en) | 2019-08-05 | 2022-11-22 | Regeneron Pharmaceuticals, Inc. | Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist |
| EP4513185A1 (en) * | 2023-08-22 | 2025-02-26 | Luxembourg Institute of Health (LIH) | Early response biomarkers for allergen immunotherapy |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK137992D0 (da) | 1992-11-13 | 1992-11-13 | Alk Lab As | Fremgangsmaade til paavisning af et immunologisk aktivt stof i en proeve under anvendelse af et maerkningsstof |
| JPH0959179A (ja) * | 1995-08-28 | 1997-03-04 | Japan Tobacco Inc | スギ花粉症予防性を有する口腔衛生剤 |
| PL194804B1 (pl) | 1998-03-16 | 2007-07-31 | Alk Abello As | Zrekombinowany alergen, sposób przygotowywania zrekombinowanego alergenu, kompozycja farmaceutyczna oraz zastosowanie zrekombinowanego alergenu do przygotowywania leku do wywoływania odpowiedzi immunologicznej u osobnika i do przygotowywania leku do leczenia, zapobiegania lub osłabiania reakcji alergicznych |
| FR2778244B1 (fr) | 1998-04-30 | 2000-07-13 | Univ Joseph Fourier | Procede d'excitation d'une cavite optique pour la detection de gaz a l'etat de traces |
| ATE414773T1 (de) | 2000-11-16 | 2008-12-15 | Alk Abello As | Mutante allergene |
| CN1668737A (zh) | 2002-05-16 | 2005-09-14 | 阿尔克-阿贝洛有限公司 | 重组Bet.V.1过敏原突变体及其方法和制备 |
| WO2004047793A1 (en) * | 2002-11-26 | 2004-06-10 | Alk-Abelló A/S | Pharmaceutical allergen product |
| CA2554337A1 (en) | 2004-02-06 | 2005-08-25 | Greer Laboratories, Inc. | Methods and compositions for dosing of allergens |
| CA2556557A1 (en) * | 2004-02-26 | 2005-09-09 | Alk Abello A/S | Method of evaluating the therapeutic potential of a vaccine for mucosal administration |
| US20060115499A1 (en) | 2004-09-27 | 2006-06-01 | Alk-Abello A/S | Liquid allergy vaccine formulation for oromucosal administration |
| CN101065146B (zh) * | 2004-11-10 | 2012-11-14 | 爱尔开-阿贝优公司 | 通过过敏反应疫苗的粘膜给药预防性治疗过敏反应的方法 |
| WO2006050729A2 (en) | 2004-11-10 | 2006-05-18 | Alk-Abellò A/S | Method of preventive treatment of allergy by mucosal administration of an allergy vaccine |
| CN101098711A (zh) * | 2005-01-07 | 2008-01-02 | 阿尔克-阿贝洛有限公司 | 通过口粘膜施用变态反应疫苗预防性治疗变态反应的方法 |
| US20060210590A1 (en) * | 2005-02-03 | 2006-09-21 | Alk-Abello A/S | Minor allergen control to increase safety of immunotherapy |
| AU2006299310A1 (en) | 2005-10-04 | 2007-04-12 | Alk-Abello A/S | Solid vaccine formulation |
| EP1814516B1 (en) | 2005-11-04 | 2012-12-26 | Alk-Abelló A/S | Use of a liquid allergy vaccine formulation for oromucosal administration |
| CA2682054A1 (en) * | 2007-03-28 | 2008-10-02 | Alk-Abello A/S | Use of an adjuvanted allergy vaccine formulation for parenteral administration |
| DE202007004567U1 (de) | 2007-03-28 | 2007-10-11 | Alk-Abelló A/S | Verwendung einer adjuvierten Allergievakzinformulierung zur parenteralen Verabreichung |
| DE202008006598U1 (de) * | 2008-04-11 | 2008-10-02 | Alk-Abelló A/S | Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung |
-
2008
- 2008-05-15 DE DE202008006598U patent/DE202008006598U1/de not_active Expired - Lifetime
-
2009
- 2009-04-08 ES ES09730293T patent/ES2406391T3/es active Active
- 2009-04-08 BR BRPI0911433A patent/BRPI0911433A2/pt not_active IP Right Cessation
- 2009-04-08 WO PCT/EP2009/054186 patent/WO2009124954A1/en not_active Ceased
- 2009-04-08 EA EA201071182A patent/EA019202B1/ru not_active IP Right Cessation
- 2009-04-08 JP JP2011503429A patent/JP5618981B2/ja not_active Expired - Fee Related
- 2009-04-08 EP EP09730293A patent/EP2265285B1/en not_active Revoked
- 2009-04-08 CA CA2720455A patent/CA2720455A1/en not_active Abandoned
- 2009-04-08 US US12/988,513 patent/US9248097B2/en active Active
- 2009-04-08 AU AU2009235490A patent/AU2009235490B2/en not_active Ceased
- 2009-04-08 CN CN2009801154343A patent/CN102014954A/zh active Pending
- 2009-04-08 MX MX2010011012A patent/MX2010011012A/es active IP Right Grant
-
2014
- 2014-01-10 US US14/152,753 patent/US20140127298A1/en not_active Abandoned
- 2014-09-16 JP JP2014187908A patent/JP2015013891A/ja active Pending
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