JP2011517941A5 - - Google Patents
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- JP2011517941A5 JP2011517941A5 JP2011503520A JP2011503520A JP2011517941A5 JP 2011517941 A5 JP2011517941 A5 JP 2011517941A5 JP 2011503520 A JP2011503520 A JP 2011503520A JP 2011503520 A JP2011503520 A JP 2011503520A JP 2011517941 A5 JP2011517941 A5 JP 2011517941A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- blood
- level
- rna encoded
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 32
- 239000008280 blood Substances 0.000 claims 22
- 210000004369 blood Anatomy 0.000 claims 22
- 206010009944 Colon cancer Diseases 0.000 claims 13
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 13
- 238000000034 method Methods 0.000 claims 13
- 239000013642 negative control Substances 0.000 claims 10
- 239000013641 positive control Substances 0.000 claims 10
- 101001055145 Homo sapiens Interleukin-2 receptor subunit beta Proteins 0.000 claims 7
- 102100026879 Interleukin-2 receptor subunit beta Human genes 0.000 claims 7
- 102100034618 Annexin A3 Human genes 0.000 claims 5
- 102100028672 C-type lectin domain family 4 member D Human genes 0.000 claims 5
- 101000756632 Homo sapiens Actin, cytoplasmic 1 Proteins 0.000 claims 5
- 101000924454 Homo sapiens Annexin A3 Proteins 0.000 claims 5
- 101000766905 Homo sapiens C-type lectin domain family 4 member D Proteins 0.000 claims 5
- 101001003581 Homo sapiens Lamin-B1 Proteins 0.000 claims 5
- 101000854777 Homo sapiens Pantetheinase Proteins 0.000 claims 5
- 101000764634 Homo sapiens Transmembrane gamma-carboxyglutamic acid protein 4 Proteins 0.000 claims 5
- 101000847156 Homo sapiens Tumor necrosis factor-inducible gene 6 protein Proteins 0.000 claims 5
- 102100026517 Lamin-B1 Human genes 0.000 claims 5
- 102100020749 Pantetheinase Human genes 0.000 claims 5
- 102100026222 Transmembrane gamma-carboxyglutamic acid protein 4 Human genes 0.000 claims 5
- 102100032807 Tumor necrosis factor-inducible gene 6 protein Human genes 0.000 claims 5
- 238000013178 mathematical model Methods 0.000 claims 4
- 238000004458 analytical method Methods 0.000 claims 3
- 238000010240 RT-PCR analysis Methods 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 235000011178 triphosphate Nutrition 0.000 claims 2
- 239000001226 triphosphate Substances 0.000 claims 2
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 claims 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102100034343 Integrase Human genes 0.000 claims 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 1
- 108091081021 Sense strand Proteins 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 238000003752 polymerase chain reaction Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12379808P | 2008-04-10 | 2008-04-10 | |
| US61/123,798 | 2008-04-10 | ||
| US12383108P | 2008-04-11 | 2008-04-11 | |
| US61/123,831 | 2008-04-11 | ||
| PCT/IB2009/005782 WO2009125303A2 (en) | 2008-04-10 | 2009-04-10 | Method and apparatus for determining a probability of colorectal cancer in a subject |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011517941A JP2011517941A (ja) | 2011-06-23 |
| JP2011517941A5 true JP2011517941A5 (https=) | 2013-05-16 |
Family
ID=41162313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503520A Pending JP2011517941A (ja) | 2008-04-10 | 2009-04-10 | 被験者における結腸直腸癌の確率を決定するための方法および装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8921074B2 (https=) |
| EP (2) | EP2868754A1 (https=) |
| JP (1) | JP2011517941A (https=) |
| CN (1) | CN102089443A (https=) |
| CA (1) | CA2721313A1 (https=) |
| SG (1) | SG189774A1 (https=) |
| WO (1) | WO2009125303A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009125303A2 (en) | 2008-04-10 | 2009-10-15 | Genenews Corporation | Method and apparatus for determining a probability of colorectal cancer in a subject |
| CN102183662A (zh) * | 2011-03-22 | 2011-09-14 | 浙江大学 | 一种大肠癌预后预测模型的建立方法 |
| CN102586418A (zh) * | 2011-12-02 | 2012-07-18 | 中国科学院合肥物质科学研究院 | 一种基于通路的特异性组合药物靶标检测方法 |
| FR2991777B1 (fr) | 2012-06-07 | 2015-08-21 | Biomerieux Sa | Procede de detection et/ou de dosage de l'annexine a3 d'un mammifere dans le sang ou au moins un de ses derives |
| WO2016164815A1 (en) | 2015-04-10 | 2016-10-13 | Applied Proteomics, Inc. | Protein biomarker panels for detecting colorectal cancer and advanced adenoma |
| JP7126704B2 (ja) * | 2016-01-28 | 2022-08-29 | ザ ユニバーシティー オブ メルボルン | 結腸直腸癌発症のリスクを評価するための方法 |
| KR102466691B1 (ko) * | 2020-06-16 | 2022-11-14 | 한양대학교 에리카산학협력단 | Tsg6 억제제를 포함하는 전이성 고형암 치료용 조성물 |
| WO2025117915A1 (en) * | 2023-11-29 | 2025-06-05 | El Capitan Biosciences, Inc. | Compositions and methods for diagnosing early-stage precancerous colorectal advanced adenomas or cancers |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
| ATE138106T1 (de) | 1988-07-20 | 1996-06-15 | David Segev | Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen |
| US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| ES2168380T3 (es) | 1994-07-15 | 2002-06-16 | Organon Teknika Bv | Utilizacion de arn polimerasa para mejorar un procedimiento de amplificacion de acido nucleico. |
| AT402203B (de) | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
| US20050123938A1 (en) | 1999-01-06 | 2005-06-09 | Chondrogene Limited | Method for the detection of osteoarthritis related gene transcripts in blood |
| ES2305087T3 (es) * | 2000-06-15 | 2008-11-01 | Novartis Vaccines And Diagnostics, Inc. | Polinucleotidos relacionados con el cancer de colon. |
| CA2499709A1 (en) * | 2002-06-19 | 2003-12-31 | Yoichi Furukawa | Method for diagnosis of colorectal tumors |
| EP1613966A2 (en) | 2003-04-08 | 2006-01-11 | Colotech A/S | A method for detection of colorectal cancer in human samples |
| US20060019256A1 (en) | 2003-06-09 | 2006-01-26 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US20050014165A1 (en) * | 2003-07-18 | 2005-01-20 | California Pacific Medical Center | Biomarker panel for colorectal cancer |
| WO2005054508A2 (en) * | 2003-12-01 | 2005-06-16 | Ipsogen | Gene expression profiling of colon cancer by dna microarrays and correlation with survival and histoclinical parameters |
| EP1777523A1 (en) * | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| TW200730825A (en) * | 2005-10-21 | 2007-08-16 | Genenews Inc | Method and apparatus for correlating levels of biomarker products with disease |
| US20120196827A1 (en) * | 2006-06-12 | 2012-08-02 | Oncomethylome Sciences S.A. | Methylation markers for early detection and prognosis of colon cancers |
| CA2665489C (en) | 2006-12-08 | 2017-08-29 | The Children's Hospital Of Philadelphia | Prrg4-associated compositions and methods of use thereof in methods of tumor diagnosis |
| WO2009125303A2 (en) | 2008-04-10 | 2009-10-15 | Genenews Corporation | Method and apparatus for determining a probability of colorectal cancer in a subject |
-
2009
- 2009-04-10 WO PCT/IB2009/005782 patent/WO2009125303A2/en not_active Ceased
- 2009-04-10 US US12/384,914 patent/US8921074B2/en active Active
- 2009-04-10 EP EP20140196147 patent/EP2868754A1/en not_active Withdrawn
- 2009-04-10 JP JP2011503520A patent/JP2011517941A/ja active Pending
- 2009-04-10 SG SG2013027172A patent/SG189774A1/en unknown
- 2009-04-10 CN CN2009801218294A patent/CN102089443A/zh active Pending
- 2009-04-10 CA CA2721313A patent/CA2721313A1/en not_active Abandoned
- 2009-04-10 EP EP09730647.6A patent/EP2281059B1/en not_active Not-in-force
-
2014
- 2014-11-18 US US14/546,433 patent/US20150141286A1/en not_active Abandoned
-
2018
- 2018-01-30 US US15/883,637 patent/US11053551B2/en not_active Expired - Fee Related
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