JP2011516478A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011516478A5 JP2011516478A5 JP2011502995A JP2011502995A JP2011516478A5 JP 2011516478 A5 JP2011516478 A5 JP 2011516478A5 JP 2011502995 A JP2011502995 A JP 2011502995A JP 2011502995 A JP2011502995 A JP 2011502995A JP 2011516478 A5 JP2011516478 A5 JP 2011516478A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- subject
- effective
- cytostatic
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 11
- -1 hydrate Substances 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 239000000824 cytostatic agent Substances 0.000 claims 3
- 230000001085 cytostatic effect Effects 0.000 claims 3
- 150000002402 hexoses Chemical class 0.000 claims 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- 102100039619 Granulocyte colony-stimulating factor Human genes 0.000 claims 2
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- 229960004641 rituximab Drugs 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 229960000575 trastuzumab Drugs 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- UEJJHQNACJXSKW-UHFFFAOYSA-N 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1C1CCC(=O)NC1=O UEJJHQNACJXSKW-UHFFFAOYSA-N 0.000 claims 1
- FUSNOPLQVRUIIM-UHFFFAOYSA-N 4-amino-2-(4,4-dimethyl-2-oxoimidazolidin-1-yl)-n-[3-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide Chemical compound O=C1NC(C)(C)CN1C(N=C1N)=NC=C1C(=O)NC1=CC=CC(C(F)(F)F)=C1 FUSNOPLQVRUIIM-UHFFFAOYSA-N 0.000 claims 1
- XAUDJQYHKZQPEU-KVQBGUIXSA-N 5-aza-2'-deoxycytidine Chemical compound O=C1N=C(N)N=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 XAUDJQYHKZQPEU-KVQBGUIXSA-N 0.000 claims 1
- NMUSYJAQQFHJEW-KVTDHHQDSA-N 5-azacytidine Chemical group O=C1N=C(N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 NMUSYJAQQFHJEW-KVTDHHQDSA-N 0.000 claims 1
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 claims 1
- MLDQJTXFUGDVEO-UHFFFAOYSA-N BAY-43-9006 Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=CC(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 MLDQJTXFUGDVEO-UHFFFAOYSA-N 0.000 claims 1
- GAGWJHPBXLXJQN-UORFTKCHSA-N Capecitabine Chemical compound C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1[C@H]1[C@H](O)[C@H](O)[C@@H](C)O1 GAGWJHPBXLXJQN-UORFTKCHSA-N 0.000 claims 1
- GAGWJHPBXLXJQN-UHFFFAOYSA-N Capecitabine Natural products C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1C1C(O)C(O)C(C)O1 GAGWJHPBXLXJQN-UHFFFAOYSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 1
- ZBNZXTGUTAYRHI-UHFFFAOYSA-N Dasatinib Chemical compound C=1C(N2CCN(CCO)CC2)=NC(C)=NC=1NC(S1)=NC=C1C(=O)NC1=C(C)C=CC=C1Cl ZBNZXTGUTAYRHI-UHFFFAOYSA-N 0.000 claims 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims 1
- 108010074604 Epoetin Alfa Proteins 0.000 claims 1
- 102000003951 Erythropoietin Human genes 0.000 claims 1
- 108090000394 Erythropoietin Proteins 0.000 claims 1
- 235000014066 European mistletoe Nutrition 0.000 claims 1
- 102000003972 Fibroblast growth factor 7 Human genes 0.000 claims 1
- 108090000385 Fibroblast growth factor 7 Proteins 0.000 claims 1
- 108010029961 Filgrastim Proteins 0.000 claims 1
- 229930091371 Fructose Natural products 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 239000005715 Fructose Substances 0.000 claims 1
- 150000004924 Gefitinib derivatives Chemical class 0.000 claims 1
- 108010024636 Glutathione Proteins 0.000 claims 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 102000004877 Insulin Human genes 0.000 claims 1
- 108090001061 Insulin Proteins 0.000 claims 1
- 102000006992 Interferon-alpha Human genes 0.000 claims 1
- 108010047761 Interferon-alpha Proteins 0.000 claims 1
- 108090000177 Interleukin-11 Proteins 0.000 claims 1
- 102000000588 Interleukin-2 Human genes 0.000 claims 1
- 108010002350 Interleukin-2 Proteins 0.000 claims 1
- 239000005511 L01XE05 - Sorafenib Substances 0.000 claims 1
- 239000002067 L01XE06 - Dasatinib Substances 0.000 claims 1
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 1
- 235000012300 Rhipsalis cassutha Nutrition 0.000 claims 1
- 241000320380 Silybum Species 0.000 claims 1
- 235000010841 Silybum marianum Nutrition 0.000 claims 1
- NAVMQTYZDKMPEU-UHFFFAOYSA-N Targretin Chemical compound CC1=CC(C(CCC2(C)C)(C)C)=C2C=C1C(=C)C1=CC=C(C(O)=O)C=C1 NAVMQTYZDKMPEU-UHFFFAOYSA-N 0.000 claims 1
- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical compound O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 claims 1
- 241000221012 Viscum Species 0.000 claims 1
- 238000001467 acupuncture Methods 0.000 claims 1
- 238000009098 adjuvant therapy Methods 0.000 claims 1
- 229940050528 albumin Drugs 0.000 claims 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 1
- 230000002022 anti-cellular effect Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229940041181 antineoplastic drug Drugs 0.000 claims 1
- 230000003416 augmentation Effects 0.000 claims 1
- 229960002756 azacitidine Drugs 0.000 claims 1
- 229960000190 bacillus calmette–guérin vaccine Drugs 0.000 claims 1
- 150000003935 benzaldehydes Chemical class 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- 229960000397 bevacizumab Drugs 0.000 claims 1
- 229960001467 bortezomib Drugs 0.000 claims 1
- GXJABQQUPOEUTA-RDJZCZTQSA-N bortezomib Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)B(O)O)NC(=O)C=1N=CC=NC=1)C1=CC=CC=C1 GXJABQQUPOEUTA-RDJZCZTQSA-N 0.000 claims 1
- 229960004117 capecitabine Drugs 0.000 claims 1
- 210000000845 cartilage Anatomy 0.000 claims 1
- 230000010261 cell growth Effects 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 229960005395 cetuximab Drugs 0.000 claims 1
- 229960000928 clofarabine Drugs 0.000 claims 1
- WDDPHFBMKLOVOX-AYQXTPAHSA-N clofarabine Chemical compound C1=NC=2C(N)=NC(Cl)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F WDDPHFBMKLOVOX-AYQXTPAHSA-N 0.000 claims 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 claims 1
- 235000017471 coenzyme Q10 Nutrition 0.000 claims 1
- 210000003022 colostrum Anatomy 0.000 claims 1
- 235000021277 colostrum Nutrition 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229960002448 dasatinib Drugs 0.000 claims 1
- 229960003603 decitabine Drugs 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 150000002016 disaccharides Chemical class 0.000 claims 1
- 229960003668 docetaxel Drugs 0.000 claims 1
- 239000003792 electrolyte Substances 0.000 claims 1
- 229940108890 emend Drugs 0.000 claims 1
- 229960003388 epoetin alfa Drugs 0.000 claims 1
- 229960005073 erlotinib hydrochloride Drugs 0.000 claims 1
- GTTBEUCJPZQMDZ-UHFFFAOYSA-N erlotinib hydrochloride Chemical compound [H+].[Cl-].C=12C=C(OCCOC)C(OCCOC)=CC2=NC=NC=1NC1=CC=CC(C#C)=C1 GTTBEUCJPZQMDZ-UHFFFAOYSA-N 0.000 claims 1
- 229940105423 erythropoietin Drugs 0.000 claims 1
- 229960000255 exemestane Drugs 0.000 claims 1
- 229960004177 filgrastim Drugs 0.000 claims 1
- 229930182830 galactose Natural products 0.000 claims 1
- 229960003180 glutathione Drugs 0.000 claims 1
- 229940087603 grape seed extract Drugs 0.000 claims 1
- 235000002532 grape seed extract Nutrition 0.000 claims 1
- 239000012493 hydrazine sulfate Substances 0.000 claims 1
- 229910000377 hydrazine sulfate Inorganic materials 0.000 claims 1
- 229960003685 imatinib mesylate Drugs 0.000 claims 1
- YLMAHDNUQAMNNX-UHFFFAOYSA-N imatinib methanesulfonate Chemical compound CS(O)(=O)=O.C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 YLMAHDNUQAMNNX-UHFFFAOYSA-N 0.000 claims 1
- DOUYETYNHWVLEO-UHFFFAOYSA-N imiquimod Chemical compound C1=CC=CC2=C3N(CC(C)C)C=NC3=C(N)N=C21 DOUYETYNHWVLEO-UHFFFAOYSA-N 0.000 claims 1
- 229960002751 imiquimod Drugs 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 229940125396 insulin Drugs 0.000 claims 1
- GOTYRUGSSMKFNF-UHFFFAOYSA-N lenalidomide Chemical compound C1C=2C(N)=CC=CC=2C(=O)N1C1CCC(=O)NC1=O GOTYRUGSSMKFNF-UHFFFAOYSA-N 0.000 claims 1
- 229960004942 lenalidomide Drugs 0.000 claims 1
- HPJKCIUCZWXJDR-UHFFFAOYSA-N letrozole Chemical compound C1=CC(C#N)=CC=C1C(N1N=CN=C1)C1=CC=C(C#N)C=C1 HPJKCIUCZWXJDR-UHFFFAOYSA-N 0.000 claims 1
- 229960003881 letrozole Drugs 0.000 claims 1
- IXOXBSCIXZEQEQ-UHTZMRCNSA-N nelarabine Chemical compound C1=NC=2C(OC)=NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O IXOXBSCIXZEQEQ-UHTZMRCNSA-N 0.000 claims 1
- 229960000801 nelarabine Drugs 0.000 claims 1
- DWAFYCQODLXJNR-BNTLRKBRSA-L oxaliplatin Chemical compound O1C(=O)C(=O)O[Pt]11N[C@@H]2CCCC[C@H]2N1 DWAFYCQODLXJNR-BNTLRKBRSA-L 0.000 claims 1
- 229960001756 oxaliplatin Drugs 0.000 claims 1
- 239000007800 oxidant agent Substances 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- 229960002404 palifermin Drugs 0.000 claims 1
- 229960001972 panitumumab Drugs 0.000 claims 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229960005079 pemetrexed Drugs 0.000 claims 1
- QOFFJEBXNKRSPX-ZDUSSCGKSA-N pemetrexed Chemical compound C1=N[C]2NC(N)=NC(=O)C2=C1CCC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 QOFFJEBXNKRSPX-ZDUSSCGKSA-N 0.000 claims 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 229960003787 sorafenib Drugs 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 229960003454 tamoxifen citrate Drugs 0.000 claims 1
- FQZYTYWMLGAPFJ-OQKDUQJOSA-N tamoxifen citrate Chemical compound [H+].[H+].[H+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.C=1C=CC=CC=1C(/CC)=C(C=1C=CC(OCCN(C)C)=CC=1)/C1=CC=CC=C1 FQZYTYWMLGAPFJ-OQKDUQJOSA-N 0.000 claims 1
- 229940099419 targretin Drugs 0.000 claims 1
- 229960004964 temozolomide Drugs 0.000 claims 1
- 229960003433 thalidomide Drugs 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 229960002663 thioctic acid Drugs 0.000 claims 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims 1
- UCFGDBYHRUNTLO-QHCPKHFHSA-N topotecan Chemical compound C1=C(O)C(CN(C)C)=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 UCFGDBYHRUNTLO-QHCPKHFHSA-N 0.000 claims 1
- 229960002190 topotecan hydrochloride Drugs 0.000 claims 1
- 239000001717 vitis vinifera seed extract Substances 0.000 claims 1
- WAEXFXRVDQXREF-UHFFFAOYSA-N vorinostat Chemical compound ONC(=O)CCCCCCC(=O)NC1=CC=CC=C1 WAEXFXRVDQXREF-UHFFFAOYSA-N 0.000 claims 1
- 229960000237 vorinostat Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4221008P | 2008-04-03 | 2008-04-03 | |
| US61/042,210 | 2008-04-03 | ||
| PCT/US2009/002134 WO2009145841A1 (en) | 2008-04-03 | 2009-04-03 | Compositions and methods for immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011516478A JP2011516478A (ja) | 2011-05-26 |
| JP2011516478A5 true JP2011516478A5 (enExample) | 2012-05-24 |
Family
ID=41267359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011502995A Pending JP2011516478A (ja) | 2008-04-03 | 2009-04-03 | 免疫療法のための組成物および方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US20090281047A1 (enExample) |
| EP (1) | EP2271350A4 (enExample) |
| JP (1) | JP2011516478A (enExample) |
| CN (1) | CN102046180A (enExample) |
| AU (1) | AU2009251848A1 (enExample) |
| CA (1) | CA2757437A1 (enExample) |
| IL (1) | IL208445A0 (enExample) |
| MX (1) | MX339451B (enExample) |
| NZ (1) | NZ588668A (enExample) |
| RU (1) | RU2010144744A (enExample) |
| WO (1) | WO2009145841A1 (enExample) |
| ZA (1) | ZA201007830B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100160368A1 (en) | 2008-08-18 | 2010-06-24 | Gregory Jefferson J | Methods of Treating Dermatological Disorders and Inducing Interferon Biosynthesis With Shorter Durations of Imiquimod Therapy |
| RS58566B1 (sr) | 2008-12-19 | 2019-05-31 | Medicis Pharmaceutical Corp | Formulacije imikuimoda niže dozne jačine i kratkih režima doziranja za lečenje aktinične keratoze |
| BR112012000797A2 (pt) | 2009-07-13 | 2016-08-09 | Medicis Pharmaceutical Corp | formulações de imiquimode de intensidade de dosagem inferior e regimes curtos de dosagem para tratamento de verrugas genitais e perianais |
| EP3056201A1 (en) * | 2010-06-07 | 2016-08-17 | Abraxis BioScience, LLC | Combination therapy methods for treating proliferative diseases |
| US20130171279A1 (en) * | 2012-01-04 | 2013-07-04 | Physicianrx, Llc | Composition for Reducing Side- and After-Effects of Cancer Treatment |
| CN103156951A (zh) * | 2013-04-11 | 2013-06-19 | 太仓市胜舟生物技术有限公司 | 一种治疗b细胞淋巴瘤的组合药物 |
| US20160296555A1 (en) * | 2013-12-20 | 2016-10-13 | Ramiro Moises VERGARA CAMPILLO | Combination of pyridoxine, folic acid and magnesium ions for treating cancer |
| SG11201805375PA (en) | 2016-02-04 | 2018-07-30 | Stem Cell Theranostics Inc | Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity |
| WO2018027029A1 (en) * | 2016-08-03 | 2018-02-08 | Zhuhai Beihai Biotech Co., Ltd. | Formulations of fosaprepitant and aprepitant |
| AU2018313719A1 (en) * | 2017-08-07 | 2020-03-19 | Joe Ernest Brown | Compositions and methods for inducing apoptosis in anaerobic cells and related clinical methods for treating cancer and pathogenic infections |
| IL307204A (en) * | 2021-03-25 | 2023-11-01 | Shmuel Robinov | Benzaldehyde extracted from rosales as foodstuff preservative, animal-feed additive, and for treatment of the covid-19 virus |
| JP7018531B1 (ja) | 2021-04-30 | 2022-02-10 | 潤 齋藤 | Ａｘｌ阻害剤 |
| WO2023161862A2 (en) * | 2022-02-24 | 2023-08-31 | Robinov Shmuel | Methods of use of benzaldehyde compositions |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4882314A (en) * | 1985-12-02 | 1989-11-21 | Rikagaku Kenkyusho | A composition and method of treating selected malignant conditions |
| US6407071B1 (en) * | 1998-06-04 | 2002-06-18 | Co-Enzyme Technology Ltd. | Method and composition for treating malignant cells |
| NO309305B1 (no) * | 1999-02-19 | 2001-01-15 | Norsk Hydro As | Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater |
-
2009
- 2009-04-03 WO PCT/US2009/002134 patent/WO2009145841A1/en not_active Ceased
- 2009-04-03 EP EP09755204A patent/EP2271350A4/en not_active Withdrawn
- 2009-04-03 CN CN2009801205538A patent/CN102046180A/zh active Pending
- 2009-04-03 RU RU2010144744/15A patent/RU2010144744A/ru not_active Application Discontinuation
- 2009-04-03 NZ NZ588668A patent/NZ588668A/xx not_active IP Right Cessation
- 2009-04-03 MX MX2010010866A patent/MX339451B/es active IP Right Grant
- 2009-04-03 AU AU2009251848A patent/AU2009251848A1/en not_active Abandoned
- 2009-04-03 CA CA2757437A patent/CA2757437A1/en not_active Abandoned
- 2009-04-03 US US12/418,342 patent/US20090281047A1/en not_active Abandoned
- 2009-04-03 JP JP2011502995A patent/JP2011516478A/ja active Pending
-
2010
- 2010-10-03 IL IL208445A patent/IL208445A0/en unknown
- 2010-11-02 ZA ZA2010/07830A patent/ZA201007830B/en unknown
-
2011
- 2011-08-19 US US13/214,022 patent/US20110311478A1/en not_active Abandoned
- 2011-08-19 US US13/213,933 patent/US20110311477A1/en not_active Abandoned
- 2011-08-19 US US13/213,819 patent/US20110311476A1/en not_active Abandoned
-
2012
- 2012-06-17 US US13/525,317 patent/US20120251490A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011516478A5 (enExample) | ||
| RU2010144744A (ru) | Композиции и способы иммунотерапии | |
| JP2020019812A5 (enExample) | ||
| US11730736B2 (en) | Anticancer agents | |
| JP2020514271A5 (enExample) | ||
| RU2018120318A (ru) | ИМИДАЗО[4,5-c]ХИНОЛИН-2-ОНОВЫЕ СОЕДИНЕНИЯ И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ РАКА | |
| KR101575706B1 (ko) | 암 치료용 선택적인 ｅｐ４ 수용체 길항제 | |
| JP2021191750A5 (enExample) | ||
| JP2017525730A5 (enExample) | ||
| AU2010234968B2 (en) | Treatment regimen utilizing neratinib for breast cancer | |
| RU2018142394A (ru) | Композиции и способы для лечения нейтропении | |
| JP2012153722A5 (enExample) | ||
| JP2014510729A5 (enExample) | ||
| JP2009536191A5 (enExample) | ||
| JP6198286B2 (ja) | 癌の処置のためのイソフラボノイド化合物および方法 | |
| JP2012158602A5 (enExample) | ||
| HRP20220351T1 (hr) | 3,5-disupstituirani pirazoli korisni kao inhibitori kinaze 1 kontrolne točke (chk1), i njihove pripreme i primjene | |
| JP2018517686A5 (enExample) | ||
| JP2010525057A5 (enExample) | ||
| ES2877712T3 (es) | Terapias combinadas para su uso en el tratamiento del cáncer de mama | |
| JP2013531068A (ja) | ４−ヨード−３−ニトロベンズアミドを抗腫瘍剤と組み合わせて用いる乳癌の治療方法 | |
| JP2017505785A5 (enExample) | ||
| JP2012522841A5 (enExample) | ||
| JP2020514344A5 (enExample) | ||
| AU2022409798A1 (en) | Use of combination therapy for treating cancer |