JP2011509650A5 - - Google Patents

Download PDF

Info

Publication number
JP2011509650A5
JP2011509650A5 JP2010526077A JP2010526077A JP2011509650A5 JP 2011509650 A5 JP2011509650 A5 JP 2011509650A5 JP 2010526077 A JP2010526077 A JP 2010526077A JP 2010526077 A JP2010526077 A JP 2010526077A JP 2011509650 A5 JP2011509650 A5 JP 2011509650A5
Authority
JP
Japan
Prior art keywords
ferm
item
antibody
antigen
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010526077A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011509650A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2009/050606 external-priority patent/WO2009088105A1/en
Publication of JP2011509650A publication Critical patent/JP2011509650A/ja
Publication of JP2011509650A5 publication Critical patent/JP2011509650A5/ja
Pending legal-status Critical Current

Links

JP2010526077A 2008-01-11 2009-01-13 ヒト化抗−α９インテグリン抗体及びその使用 Pending JP2011509650A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2052708P 2008-01-11 2008-01-11
PCT/JP2009/050606 WO2009088105A1 (en) 2008-01-11 2009-01-13 HUMANIZED ANTI-α9 INTEGRIN ANTIBODIES AND THE USES THEREOF

Publications (2)

Publication Number Publication Date
JP2011509650A JP2011509650A (ja) 2011-03-31
JP2011509650A5 true JP2011509650A5 (https=) 2012-02-09

Family

ID=40853211

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010526077A Pending JP2011509650A (ja) 2008-01-11 2009-01-13 ヒト化抗−α９インテグリン抗体及びその使用

Country Status (8)

Country Link
US (1) US8821863B2 (https=)
EP (2) EP2245156A4 (https=)
JP (1) JP2011509650A (https=)
KR (1) KR101597842B1 (https=)
CN (1) CN101918555B (https=)
AU (1) AU2009203350B2 (https=)
CA (1) CA2711771C (https=)
WO (1) WO2009088105A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101429783B1 (ko) * 2006-07-12 2014-08-18 가부시키가이샤 진 테크노 사이언스 항 인간 α９ 인테그린 항체와 그 용도
EP2406285B1 (en) * 2009-03-10 2016-03-09 Gene Techno Science Co., Ltd. Generation, expression and characterization of the humanized k33n monoclonal antibody
WO2011004847A1 (ja) * 2009-07-07 2011-01-13 一般財団法人化学及血清療法研究所 新規ヒト化抗ヒトα９インテグリン抗体
DK2877580T3 (en) 2012-07-27 2019-04-23 Hope City VAT VACCINE TO DELIVER A UL128 COMPLEX AND PREVENT CMV INFECTION
US20150322152A1 (en) * 2012-11-30 2015-11-12 Institut Pasteur Use of anti-fcyri and/or anti-fcyriia antibodies for treating arthritis, inflammation, thrombocytopenia and allergic shock
TWI700300B (zh) * 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第ｖｉｉｉ凝血因子（ｆｖｉｉｉ）機能替代活性的物質之抗體
CN108137691B (zh) 2015-09-02 2021-10-19 耶路撒冷希伯来大学伊萨姆研究发展有限公司 特异性针对人类t-细胞免疫球蛋白和itim结构域(tigit)的抗体
EP3347045A4 (en) 2015-09-10 2019-08-28 City of Hope MVA-GH / GL-PC VACCINATED ANTIBODIES FOR NEUTRALIZING THE INFECTIOSITY OF HUMAN CYTOMEGALOVIRUS AND METHOD THEREFOR
US11319380B2 (en) 2018-06-04 2022-05-03 Precigen, Inc. MUC16 specific chimeric antigen receptors and uses thereof
CN117285619B (zh) * 2023-09-28 2025-11-25 广西壮族自治区兽医研究所 一种鸡细小病毒的单克隆抗体及其应用

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
WO1988007089A1 (en) 1987-03-18 1988-09-22 Medical Research Council Altered antibodies
US5258498A (en) 1987-05-21 1993-11-02 Creative Biomolecules, Inc. Polypeptide linkers for production of biosynthetic proteins
JP3095168B2 (ja) 1988-02-05 2000-10-03 エル． モリソン，シェリー ドメイン‐変性不変部を有する抗体
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
WO1991010737A1 (en) 1990-01-11 1991-07-25 Molecular Affinities Corporation Production of antibodies using gene libraries
US5780225A (en) 1990-01-12 1998-07-14 Stratagene Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
US5314995A (en) 1990-01-22 1994-05-24 Oncogen Therapeutic interleukin-2-antibody based fusion proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE300615T1 (de) * 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
US5698426A (en) 1990-09-28 1997-12-16 Ixsys, Incorporated Surface expression libraries of heteromeric receptors
CA2405246A1 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with alterred binding properties
DK0580737T3 (da) 1991-04-10 2004-11-01 Scripps Research Inst Heterodimere receptorbiblioteker ved anvendelse af phagemider
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
CA2110799A1 (en) 1991-06-14 1992-12-23 Arnold H. Horwitz Microbially-produced antibody fragments and their conjugates
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
ES2341666T3 (es) 1991-12-02 2010-06-24 Medimmune Limited Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
US5733743A (en) 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
ZA932522B (en) 1992-04-10 1993-12-20 Res Dev Foundation Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
JPH08501085A (ja) 1992-08-26 1996-02-06 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗腫瘍剤としてのサイトカインｉｐ−１０の利用
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
EP0733070A1 (en) 1993-12-08 1996-09-25 Genzyme Corporation Process for generating specific antibodies
PT1231268E (pt) 1994-01-31 2005-11-30 Univ Boston Bancos de anticorpos policlonais
US5516637A (en) 1994-06-10 1996-05-14 Dade International Inc. Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
JP2978435B2 (ja) 1996-01-24 1999-11-15 チッソ株式会社 アクリロキシプロピルシランの製造方法
US20040234524A1 (en) 2001-04-05 2004-11-25 Toshimitsu Uede Anti-osteopontin antibody and use thereof
US7456260B2 (en) * 2002-06-17 2008-11-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Humanized antibody
ITRM20030601A1 (it) * 2003-12-24 2005-06-25 Lay Line Genomics Spa Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
EP1797897A4 (en) * 2004-08-03 2008-06-18 Mochida Pharm Co Ltd MEDICAL COMPOSITION WITH A MELTRINE ANTAGONIST
IN266863B (https=) 2005-01-13 2015-06-10 Gene Techno Science Co Ltd
KR101429783B1 (ko) 2006-07-12 2014-08-18 가부시키가이샤 진 테크노 사이언스 항 인간 α９ 인테그린 항체와 그 용도

Similar Documents

Publication Publication Date Title
JP2011509650A5 (https=)
JP2013198490A5 (https=)
NZ621170A (en) Anti-human cd52 immunoglobulins
WO2013037484A3 (en) Anti-aplhabetatcr antibody
JP2015028021A5 (https=)
BRPI0908508A2 (pt) anticorpo monoclonal nkg2a anti-humano humanizado
WO2009120927A3 (en) Methods of treatment
NZ604643A (en) S100a4 antibodies and therapeutic uses thereof
IL197928A (en) A monoclonal antibody munched on steap-1, its immunoconjugates its uses
NZ592036A (en) Methods for producing antibodies from plasma cells
NZ602294A (en) Monoclonal antibodies against c-met
IL202232A (en) A method of making a human antibody derived from a rabbit parent antibody that binds to a desired antigen as well as a human antibody or fragment thereof produced by this method
HRP20140266T1 (hr) Postupci inhibiranja vezanja endosijalina na ligande
WO2008043145A8 (en) Hybridomas producing antibodies against non functional p2x7 receptor
RU2017128882A (ru) Антитела к биотину и способы их применения
ZA200905447B (en) Multivariable antigens complexed with targeting humanized monoclonal antibody
NZ597023A (en) Monoclonal antibodies that bind to hGM-CSF and medical compositions comprising same
JP2016520514A5 (https=)
PH12012501525A1 (en) A monoclonal antibody to cd44 for use in the treatment of head and neck squamous cell carcinoma
SG178886A1 (en) Humanized anti-cdcp1 antibodies
MX341958B (es) Anticuerpos contra el il33r humano y usos de los mismos.
JP2010509937A5 (https=)
BRPI0821211A2 (pt) Anticorpo anti-humano cd34 humanizado, o método de preparação e usos do mesmo.
NZ595863A (en) Antibodies to egfl7 and methods for their use
JP2011237442A5 (https=)