JP2011508197A5 - - Google Patents
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- Publication number
- JP2011508197A5 JP2011508197A5 JP2010538909A JP2010538909A JP2011508197A5 JP 2011508197 A5 JP2011508197 A5 JP 2011508197A5 JP 2010538909 A JP2010538909 A JP 2010538909A JP 2010538909 A JP2010538909 A JP 2010538909A JP 2011508197 A5 JP2011508197 A5 JP 2011508197A5
- Authority
- JP
- Japan
- Prior art keywords
- body fluid
- autoantibodies
- collected
- cancer
- subjects
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001124 body fluid Anatomy 0.000 claims 20
- 239000010839 body fluid Substances 0.000 claims 20
- 206010028980 Neoplasm Diseases 0.000 claims 15
- 239000000463 material Substances 0.000 claims 11
- 201000011510 cancer Diseases 0.000 claims 9
- 238000001514 detection method Methods 0.000 claims 8
- 238000003018 immunoassay Methods 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 206010003445 Ascites Diseases 0.000 claims 3
- 208000002151 Pleural effusion Diseases 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 239000010836 blood and blood product Substances 0.000 claims 3
- 229940125691 blood product Drugs 0.000 claims 3
- 210000000416 exudates and transudate Anatomy 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 230000009870 specific binding Effects 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000012895 dilution Substances 0.000 claims 2
- 238000010790 dilution Methods 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000000439 tumor marker Substances 0.000 claims 2
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 230000001613 neoplastic effect Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0725239.8 | 2007-12-24 | ||
| GBGB0725239.8A GB0725239D0 (en) | 2007-12-24 | 2007-12-24 | Calibrator for autoantibody assay |
| US1668907P | 2007-12-26 | 2007-12-26 | |
| US61/016,689 | 2007-12-26 | ||
| PCT/GB2008/004260 WO2009081165A1 (en) | 2007-12-24 | 2008-12-23 | Calibrator for immunoassays |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011508197A JP2011508197A (ja) | 2011-03-10 |
| JP2011508197A5 true JP2011508197A5 (enExample) | 2012-02-16 |
| JP5594776B2 JP5594776B2 (ja) | 2014-09-24 |
Family
ID=39092384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538909A Expired - Fee Related JP5594776B2 (ja) | 2007-12-24 | 2008-12-23 | イムノアッセイのためのキャリブレータ |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20090176319A1 (enExample) |
| EP (1) | EP2223114B1 (enExample) |
| JP (1) | JP5594776B2 (enExample) |
| CN (1) | CN101952723B (enExample) |
| AU (1) | AU2008339624B2 (enExample) |
| BR (1) | BRPI0821397B1 (enExample) |
| CA (1) | CA2707025C (enExample) |
| CY (1) | CY1118253T1 (enExample) |
| DK (1) | DK2223114T3 (enExample) |
| ES (1) | ES2588731T3 (enExample) |
| GB (1) | GB0725239D0 (enExample) |
| HR (1) | HRP20161109T1 (enExample) |
| IL (1) | IL205733A (enExample) |
| PT (1) | PT2223114T (enExample) |
| SG (1) | SG186684A1 (enExample) |
| SI (1) | SI2223114T1 (enExample) |
| WO (1) | WO2009081165A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9810040D0 (en) * | 1998-05-11 | 1998-07-08 | Univ Nottingham | Blood borne tumour markers |
| GB9827228D0 (en) * | 1998-12-10 | 1999-02-03 | Univ Nottingham | Cancer detection method and reagents |
| US20030232399A1 (en) * | 2000-06-14 | 2003-12-18 | Robertson John Forsyth Russell | Cancer detection methods and reagents |
| GB2424070B (en) * | 2002-11-14 | 2007-06-27 | Univ Nottingham | Methods for preparing tumour marker proteins |
| US7858323B2 (en) | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
| NZ563466A (en) | 2005-05-27 | 2009-12-24 | Oncimmune Ltd | Improved immunoassay methods |
| GB2426581A (en) * | 2005-05-27 | 2006-11-29 | Univ Nottingham | Immunoassay methods |
| WO2007136025A1 (ja) * | 2006-05-19 | 2007-11-29 | Bml, Inc. | 感染症の検出方法 |
| CN101632020B (zh) | 2006-09-13 | 2013-11-27 | 昂西免疫有限公司 | 改进的免疫测定方法 |
| GB0725239D0 (en) * | 2007-12-24 | 2008-02-06 | Oncimmune Ltd | Calibrator for autoantibody assay |
| WO2011116209A2 (en) | 2010-03-17 | 2011-09-22 | The Regents Of The University Of Michigan | Using phage epitopes to profile the immune response |
| US11662564B2 (en) | 2017-06-15 | 2023-05-30 | Shenzhen Prs Limited | Paraffin shield coating for microscope slide |
| WO2018228577A1 (en) * | 2017-06-15 | 2018-12-20 | Sunstone Scientific Limited. | Method for ihc antigen imaging scale extrapolation |
| US12313834B2 (en) | 2017-06-15 | 2025-05-27 | Shenzhen Prs Limited | Paraffin shield coating for microscope slide |
| BR102021003012A2 (pt) | 2020-02-19 | 2021-11-30 | Univ Berlin Charite | Métodos para o diagnóstico de infecção por sars-cov-2, kit e usos |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4241044A (en) * | 1978-12-28 | 1980-12-23 | Abbott Laboratories | Method of diagnosing cancer by detecting elevated anti-T antibody activity |
| JPS60192263A (ja) * | 1984-03-13 | 1985-09-30 | Teijin Ltd | 免疫複合体測定用標準物質及びそれを用いた免疫複合体の測定法 |
| NZ211453A (en) * | 1984-03-22 | 1989-01-06 | Biotechnology Research Enterpr | Aryl azides, their preparation and use in the detection, localisation and isolation of polynucleotides |
| US4937185A (en) * | 1987-07-31 | 1990-06-26 | The Ohio State University Research Foundation | Detection of circulating antibodies to a cancer marker protein |
| US7282345B1 (en) * | 1989-08-04 | 2007-10-16 | Schering Ag | C-erbB-2 external domain: GP75 |
| US5110911A (en) * | 1989-11-02 | 1992-05-05 | Biomira, Inc. | Human tumor-associated thomsen-friedenreich antigen |
| US5157020A (en) * | 1990-05-24 | 1992-10-20 | Research Corporation Tech., Inc. | Synthetic senescent cell antigen |
| DE4120412C1 (enExample) * | 1991-06-20 | 1993-01-07 | Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De | |
| JPH067191A (ja) * | 1991-09-26 | 1994-01-18 | Konica Corp | モノクローナル抗体、それを産生するハイブリド−マ、その対応抗原及びそれを用いた測定方法 |
| US6322989B1 (en) * | 1991-11-25 | 2001-11-27 | Yoreh Biotechnologies, Ltd. | Whole blood/mitogen assay for the early detection of a subject with ovarian or breast cancer and kit |
| US6280962B1 (en) * | 1991-11-25 | 2001-08-28 | Yoreh Biotechnologies Ltd. | Whole blood/mitogen assay for the early detection of a subject with cancer and kit |
| ATE408012T1 (de) * | 1991-12-02 | 2008-09-15 | Medical Res Council | Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken |
| EP0625909A4 (en) * | 1992-02-12 | 1997-03-05 | Robert Perper | Autoantibody assay and usage in the control of human disease. |
| WO1993021529A1 (en) * | 1992-04-14 | 1993-10-28 | Duke University | Method of detecting tumors containing complexes of p53 and hsp70 |
| US5801005A (en) * | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
| US5763164A (en) * | 1993-04-16 | 1998-06-09 | Northwestern University | Immunogenic cancer proteins and peptides and methods of use |
| US5747268A (en) * | 1993-04-22 | 1998-05-05 | Dade International Inc. | Tumor marker control |
| US5744144A (en) * | 1993-07-30 | 1998-04-28 | University Of Pittsburgh University Patent Committee Policy And Procedures | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
| US5721105A (en) * | 1994-02-20 | 1998-02-24 | B.R.A.H.M.S. Diagnostica Gmbh | Method for the immunological determination of proteins and kit for carrying out the method |
| US5789655A (en) * | 1994-05-13 | 1998-08-04 | The Regents Of The University Of California | Transgenic animals expressing artificial epitope-tagged proteins |
| US5561049A (en) * | 1994-09-21 | 1996-10-01 | Behringwerke Ag | Method for detecting antibodies |
| US5876728A (en) * | 1995-02-15 | 1999-03-02 | Howard David Kass | Natural composition extracted from plants used in the treatment of cancer |
| US5723343A (en) * | 1995-08-28 | 1998-03-03 | University Of Florida | Autoantibodies in patients with acquired hypoparathyroidism and assay method therefor |
| JP3472048B2 (ja) * | 1995-10-09 | 2003-12-02 | 鐘淵化学工業株式会社 | 自己免疫疾患の診断薬 |
| WO1998006746A2 (en) * | 1996-08-16 | 1998-02-19 | The Johns Hopkins University School Of Medicine | Melanoma cell lines expressing shared immunodominant melanoma antigens and methods of using same |
| US6306636B1 (en) * | 1997-09-19 | 2001-10-23 | Arch Development Corporation | Nucleic acid segments encoding wheat acetyl-CoA carboxylase |
| DE19805815C1 (de) * | 1998-02-13 | 1999-11-11 | Ansgar W Lohse | Diagnostikum zum Erkennen der autoimmunen Hepatitis |
| US6388062B1 (en) * | 1998-05-08 | 2002-05-14 | The Wistar Institute Of Anatomy And Biology | Modified p53 tetramerization domains having hydrophobic amino acid substitutions |
| GB9810040D0 (en) * | 1998-05-11 | 1998-07-08 | Univ Nottingham | Blood borne tumour markers |
| JP3268494B2 (ja) * | 1998-10-01 | 2002-03-25 | 俊成 広畑 | 全身性エリテマトーデス病態診断剤 |
| US6387639B1 (en) * | 1998-11-10 | 2002-05-14 | Sloan-Kettering Institute For Cancer Research | Ma family polypeptides and anti-Ma antibodies |
| GB9827228D0 (en) * | 1998-12-10 | 1999-02-03 | Univ Nottingham | Cancer detection method and reagents |
| US7807810B2 (en) * | 1999-04-08 | 2010-10-05 | The Ohio State University Research Foundation | Nucleic acids encoding the major outer membrane protein of the causative agent of human granulocytic ehrlichiosis and peptides encoded thereby |
| US6645465B2 (en) * | 1999-08-06 | 2003-11-11 | Michigan, University Of The Regents | Annexin proteins and autoantibodies as serum markers for cancer |
| DE19939575C1 (de) * | 1999-08-20 | 2001-08-02 | Orgentec Diagnostika Gmbh | Verfahren zur Diagnose von Sjögren-Syndrom |
| US20020064801A1 (en) * | 1999-12-01 | 2002-05-30 | Ryan Jeffrey R. | Novel and practical serological assay for the clinical diagnosis of leishmaniasis |
| US6667160B2 (en) * | 2000-03-15 | 2003-12-23 | Kenneth D. Fine | Method for diagnosing immunologic food sensitivity |
| AU4465001A (en) * | 2000-03-30 | 2001-10-15 | Nippon Kayaku Kabushiki Kaisha | Method of examining cancer by assaying autoantibody against mdm2 and reagent therefor |
| US20030232399A1 (en) * | 2000-06-14 | 2003-12-18 | Robertson John Forsyth Russell | Cancer detection methods and reagents |
| US20030138860A1 (en) * | 2000-06-14 | 2003-07-24 | Robertson John Forsyth Russell | Cancer detection methods and reagents |
| WO2003073101A2 (en) * | 2001-06-21 | 2003-09-04 | New York University | Mycobacterial proteins as early antigens for serodiagnosis and vaccines |
| US20030049692A1 (en) * | 2002-09-16 | 2003-03-13 | Norman Latov | Detection of anti-glycolipid antibodies by latex agglutination assay |
| GB2424070B (en) * | 2002-11-14 | 2007-06-27 | Univ Nottingham | Methods for preparing tumour marker proteins |
| WO2004063226A2 (en) * | 2002-12-27 | 2004-07-29 | Applied Research Systems Ars Holding N.V. | Novel fibrillin-like polypeptides |
| JP2005352771A (ja) * | 2004-06-10 | 2005-12-22 | Hitachi Software Eng Co Ltd | 発現プロファイルによるパターン認識システム |
| US20060141547A1 (en) * | 2004-11-16 | 2006-06-29 | Das Hasi R | Novel diagnostic marker, a diagnostic kit and a method for diagnosis of rheumatoid arthritis |
| GB2426581A (en) * | 2005-05-27 | 2006-11-29 | Univ Nottingham | Immunoassay methods |
| EP1789435B1 (en) * | 2005-09-12 | 2010-02-24 | Industry Foundation of Chonnam National University | A method for production of mature natural killer cell |
| TWI304443B (en) * | 2005-12-30 | 2008-12-21 | Nat Health Research Institutes | Alpha-enolase specific antibody and method of use |
| CN101632020B (zh) * | 2006-09-13 | 2013-11-27 | 昂西免疫有限公司 | 改进的免疫测定方法 |
| AU2007297310B2 (en) * | 2006-09-13 | 2013-11-07 | Oncimmune Limited | Improved immunoassay methods |
| GB0725239D0 (en) * | 2007-12-24 | 2008-02-06 | Oncimmune Ltd | Calibrator for autoantibody assay |
| GB201411060D0 (en) * | 2014-06-20 | 2014-08-06 | Oncimmune Ltd | Improved immunoassay method |
-
2007
- 2007-12-24 GB GBGB0725239.8A patent/GB0725239D0/en not_active Ceased
-
2008
- 2008-12-23 BR BRPI0821397A patent/BRPI0821397B1/pt not_active IP Right Cessation
- 2008-12-23 PT PT88652649T patent/PT2223114T/pt unknown
- 2008-12-23 DK DK08865264.9T patent/DK2223114T3/en active
- 2008-12-23 JP JP2010538909A patent/JP5594776B2/ja not_active Expired - Fee Related
- 2008-12-23 SG SG2012095006A patent/SG186684A1/en unknown
- 2008-12-23 AU AU2008339624A patent/AU2008339624B2/en not_active Ceased
- 2008-12-23 US US12/343,047 patent/US20090176319A1/en not_active Abandoned
- 2008-12-23 CN CN200880122385.1A patent/CN101952723B/zh not_active Expired - Fee Related
- 2008-12-23 ES ES08865264.9T patent/ES2588731T3/es active Active
- 2008-12-23 CA CA2707025A patent/CA2707025C/en active Active
- 2008-12-23 SI SI200831684A patent/SI2223114T1/sl unknown
- 2008-12-23 HR HRP20161109TT patent/HRP20161109T1/hr unknown
- 2008-12-23 EP EP08865264.9A patent/EP2223114B1/en not_active Not-in-force
- 2008-12-23 WO PCT/GB2008/004260 patent/WO2009081165A1/en not_active Ceased
-
2010
- 2010-05-13 IL IL205733A patent/IL205733A/en active IP Right Grant
-
2016
- 2016-09-23 US US15/274,012 patent/US20170074884A1/en not_active Abandoned
- 2016-11-17 CY CY20161101189T patent/CY1118253T1/el unknown
-
2020
- 2020-11-19 US US16/952,473 patent/US20210318320A1/en not_active Abandoned
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