JP2011508059A5 - - Google Patents
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- Publication number
- JP2011508059A5 JP2011508059A5 JP2010540781A JP2010540781A JP2011508059A5 JP 2011508059 A5 JP2011508059 A5 JP 2011508059A5 JP 2010540781 A JP2010540781 A JP 2010540781A JP 2010540781 A JP2010540781 A JP 2010540781A JP 2011508059 A5 JP2011508059 A5 JP 2011508059A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- group
- hydrophilic
- monomer
- silicon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 31
- 239000000178 monomer Substances 0.000 claims 17
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 10
- 229920001400 block copolymer Polymers 0.000 claims 10
- 229910052710 silicon Inorganic materials 0.000 claims 10
- 239000010703 silicon Substances 0.000 claims 10
- 239000003607 modifier Substances 0.000 claims 9
- -1 polydimethylsiloxane Polymers 0.000 claims 9
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 7
- 125000000524 functional group Chemical group 0.000 claims 5
- 150000001299 aldehydes Chemical class 0.000 claims 4
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 3
- PEEHTFAAVSWFBL-UHFFFAOYSA-N Maleimide Chemical compound O=C1NC(=O)C=C1 PEEHTFAAVSWFBL-UHFFFAOYSA-N 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 3
- 239000000017 hydrogel Substances 0.000 claims 3
- 150000002576 ketones Chemical class 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- VAYTZRYEBVHVLE-UHFFFAOYSA-N 1,3-dioxol-2-one Chemical compound O=C1OC=CO1 VAYTZRYEBVHVLE-UHFFFAOYSA-N 0.000 claims 2
- KCOPAESEGCGTKM-UHFFFAOYSA-N 1,3-oxazol-4-one Chemical compound O=C1COC=N1 KCOPAESEGCGTKM-UHFFFAOYSA-N 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 2
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 claims 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 2
- 241001061127 Thione Species 0.000 claims 2
- 150000008065 acid anhydrides Chemical class 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 150000001412 amines Chemical class 0.000 claims 2
- 238000010560 atom transfer radical polymerization reaction Methods 0.000 claims 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 2
- 150000001733 carboxylic acid esters Chemical class 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 150000002118 epoxides Chemical class 0.000 claims 2
- 239000007943 implant Substances 0.000 claims 2
- 239000003999 initiator Substances 0.000 claims 2
- 239000012948 isocyanate Substances 0.000 claims 2
- 150000002513 isocyanates Chemical class 0.000 claims 2
- 150000002540 isothiocyanates Chemical class 0.000 claims 2
- 150000003951 lactams Chemical class 0.000 claims 2
- 150000002596 lactones Chemical class 0.000 claims 2
- GASFVSRUEBGMDI-UHFFFAOYSA-N n-aminohydroxylamine Chemical compound NNO GASFVSRUEBGMDI-UHFFFAOYSA-N 0.000 claims 2
- 230000000269 nucleophilic effect Effects 0.000 claims 2
- 150000002905 orthoesters Chemical class 0.000 claims 2
- PTMHPRAIXMAOOB-UHFFFAOYSA-L phosphoramidate Chemical compound NP([O-])([O-])=O PTMHPRAIXMAOOB-UHFFFAOYSA-L 0.000 claims 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 229910000077 silane Inorganic materials 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 150000003457 sulfones Chemical class 0.000 claims 2
- WMGWLIAIMDFMIQ-UHFFFAOYSA-N sulfuroiodidic acid Chemical compound OS(I)(=O)=O WMGWLIAIMDFMIQ-UHFFFAOYSA-N 0.000 claims 2
- 150000003573 thiols Chemical class 0.000 claims 2
- GWIKYPMLNBTJHR-UHFFFAOYSA-M thiosulfonate group Chemical group S(=S)(=O)[O-] GWIKYPMLNBTJHR-UHFFFAOYSA-M 0.000 claims 2
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 claims 2
- ZJIFDEVVTPEXDL-UHFFFAOYSA-N (2,5-dioxopyrrolidin-1-yl) hydrogen carbonate Chemical compound OC(=O)ON1C(=O)CCC1=O ZJIFDEVVTPEXDL-UHFFFAOYSA-N 0.000 claims 1
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 claims 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims 1
- BTBWSRPRAGXJJV-UHFFFAOYSA-N 2h-benzotriazole;carbonic acid Chemical compound OC(O)=O.C1=CC=C2NN=NC2=C1 BTBWSRPRAGXJJV-UHFFFAOYSA-N 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical group CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 claims 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 claims 1
- 125000003158 alcohol group Chemical group 0.000 claims 1
- HAXFWIACAGNFHA-UHFFFAOYSA-N aldrithiol Chemical compound C=1C=CC=NC=1SSC1=CC=CC=N1 HAXFWIACAGNFHA-UHFFFAOYSA-N 0.000 claims 1
- ACBQROXDOHKANW-UHFFFAOYSA-N bis(4-nitrophenyl) carbonate Chemical compound C1=CC([N+](=O)[O-])=CC=C1OC(=O)OC1=CC=C([N+]([O-])=O)C=C1 ACBQROXDOHKANW-UHFFFAOYSA-N 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- GYZLOYUZLJXAJU-UHFFFAOYSA-N diglycidyl ether Chemical compound C1OC1COCC1CO1 GYZLOYUZLJXAJU-UHFFFAOYSA-N 0.000 claims 1
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 210000003709 heart valve Anatomy 0.000 claims 1
- 150000002373 hemiacetals Chemical class 0.000 claims 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims 1
- WFKDPJRCBCBQNT-UHFFFAOYSA-N n,2-dimethylprop-2-enamide Chemical compound CNC(=O)C(C)=C WFKDPJRCBCBQNT-UHFFFAOYSA-N 0.000 claims 1
- RQAKESSLMFZVMC-UHFFFAOYSA-N n-ethenylacetamide Chemical compound CC(=O)NC=C RQAKESSLMFZVMC-UHFFFAOYSA-N 0.000 claims 1
- 125000005375 organosiloxane group Chemical group 0.000 claims 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 230000009257 reactivity Effects 0.000 claims 1
- 239000011550 stock solution Substances 0.000 claims 1
- 150000003555 thioacetals Chemical class 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
- 210000000626 ureter Anatomy 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1684507P | 2007-12-27 | 2007-12-27 | |
| US12/334,618 US7942929B2 (en) | 2007-12-27 | 2008-12-15 | Coating solutions comprising segmented reactive block copolymers |
| PCT/US2008/086989 WO2009085755A1 (en) | 2007-12-27 | 2008-12-16 | Coating solutions comprising segmented reactive block copolymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011508059A JP2011508059A (ja) | 2011-03-10 |
| JP2011508059A5 true JP2011508059A5 (https=) | 2012-02-09 |
Family
ID=40288871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010540781A Pending JP2011508059A (ja) | 2007-12-27 | 2008-12-16 | セグメント化反応性ブロックコポリマーを含むコーティング溶液 |
Country Status (4)
| Country | Link |
|---|---|
| EP (2) | EP2597113A1 (https=) |
| JP (1) | JP2011508059A (https=) |
| CN (1) | CN101977972B (https=) |
| WO (1) | WO2009085755A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9522980B2 (en) | 2010-05-06 | 2016-12-20 | Johnson & Johnson Vision Care, Inc. | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same |
| US9170349B2 (en) | 2011-05-04 | 2015-10-27 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| US20130203813A1 (en) | 2011-05-04 | 2013-08-08 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| WO2013074535A1 (en) * | 2011-11-15 | 2013-05-23 | Novartis Ag | A silicone hydrogel lens with a crosslinked hydrophilic coating |
| US9244196B2 (en) | 2012-05-25 | 2016-01-26 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US10073192B2 (en) | 2012-05-25 | 2018-09-11 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US9297929B2 (en) | 2012-05-25 | 2016-03-29 | Johnson & Johnson Vision Care, Inc. | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers |
| CA2874718A1 (en) * | 2012-05-25 | 2013-11-28 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US9486311B2 (en) | 2013-02-14 | 2016-11-08 | Shifamed Holdings, Llc | Hydrophilic AIOL with bonding |
| US10195018B2 (en) | 2013-03-21 | 2019-02-05 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| CA3193600A1 (en) | 2013-03-21 | 2014-09-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| AU2014348502B2 (en) * | 2013-11-15 | 2019-08-15 | Tangible Science, Inc. | Contact lens with a hydrophilic layer |
| EP4574093A3 (en) | 2014-08-26 | 2025-09-17 | Shifamed Holdings, LLC | Accommodating intraocular lens |
| CN104844746B (zh) * | 2015-05-05 | 2017-03-29 | 南开大学 | 一种具有多重刺激响应性的水溶性聚合物及其制备方法 |
| FR3038903B1 (fr) * | 2015-07-17 | 2019-05-24 | Universite Du Mans | Compose polyurethane ignifuge comprenant des elements oligomeres phosphores de longueur controlee |
| US10642069B2 (en) | 2015-10-07 | 2020-05-05 | Seed Co., Ltd. | Production method of unhydrated ophthalmic lens and unhydrated ophthalmic lens |
| FR3042794B1 (fr) * | 2015-10-23 | 2020-03-27 | Arkema France | Procede permettant la creation de structures nanometriques par l'auto-assemblage de copolymeres di-blocs |
| CA3005338A1 (en) | 2015-11-18 | 2017-05-26 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lens |
| US11141263B2 (en) | 2015-11-18 | 2021-10-12 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lens |
| KR102089715B1 (ko) * | 2016-06-22 | 2020-03-16 | 주식회사 엘지화학 | 공중합체, 이의 제조 방법, 및 이를 포함하는 친수성 코팅 조성물 |
| CN120000379A (zh) | 2016-12-23 | 2025-05-16 | 施菲姆德控股有限责任公司 | 多片式调节性人工晶状体及其制造和使用方法 |
| US10350056B2 (en) | 2016-12-23 | 2019-07-16 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lenses and methods for making and using same |
| EP3634308A4 (en) | 2017-05-30 | 2021-02-24 | Shifamed Holdings, LLC | SURFACE TREATMENTS FOR ACCEPTING INTRAOCULAR LENSES AND RELATED PROCEDURES AND DEVICES |
| EP3634309B1 (en) | 2017-06-07 | 2023-05-24 | Shifamed Holdings, LLC | Adjustable optical power intraocular lenses |
| US10836928B2 (en) * | 2017-12-15 | 2020-11-17 | Ppg Industries Ohio, Inc. | Polyoxazoline curing for packaging coating compositions |
| CN109820625A (zh) * | 2018-09-30 | 2019-05-31 | 四川大学 | 一种交联的人工生物瓣膜处理方法 |
| DE102018127812B4 (de) * | 2018-11-07 | 2020-06-18 | Fachhochschule Kiel | Kontaktlinse mit einer Oberflächenbeschichtung und Herstellungsverfahren |
| US12521232B2 (en) | 2019-07-11 | 2026-01-13 | Shifamed Holdings, Llc | Accommodating intraocular lenses and associated methods |
| KR20230051234A (ko) * | 2020-09-03 | 2023-04-17 | 다이킨 고교 가부시키가이샤 | 실리콘 공중합체 |
| KR20240023596A (ko) * | 2021-06-24 | 2024-02-22 | 니치유 가부시키가이샤 | 콘택트 렌즈 및 그 렌즈의 제조 방법 |
| US20250321364A1 (en) * | 2024-04-15 | 2025-10-16 | Bausch + Lomb Ireland Limited | Surface modified ophthalmic devices |
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| US4136250A (en) | 1977-07-20 | 1979-01-23 | Ciba-Geigy Corporation | Polysiloxane hydrogels |
| US4153641A (en) | 1977-07-25 | 1979-05-08 | Bausch & Lomb Incorporated | Polysiloxane composition and contact lens |
| US4327203A (en) | 1981-02-26 | 1982-04-27 | Bausch & Lomb Incorporated | Polysiloxane with cycloalkyl modifier composition and biomedical devices |
| US4355147A (en) | 1981-02-26 | 1982-10-19 | Bausch & Lomb Incorporated | Polysiloxane with polycyclic modifier composition and biomedical devices |
| US4740533A (en) | 1987-07-28 | 1988-04-26 | Ciba-Geigy Corporation | Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof |
| US5270418A (en) | 1987-04-02 | 1993-12-14 | Bausch & Lomb Incorporated | Polymer compositions for contact lenses |
| US4910277A (en) | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US4954587A (en) | 1988-07-05 | 1990-09-04 | Ciba-Geigy Corporation | Dimethylacrylamide-copolymer hydrogels with high oxygen permeability |
| US5070215A (en) | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
| US5034461A (en) | 1989-06-07 | 1991-07-23 | Bausch & Lomb Incorporated | Novel prepolymers useful in biomedical devices |
| US5010141A (en) | 1989-10-25 | 1991-04-23 | Ciba-Geigy Corporation | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof |
| US5079319A (en) | 1989-10-25 | 1992-01-07 | Ciba-Geigy Corporation | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof |
| US5310779A (en) | 1991-11-05 | 1994-05-10 | Bausch & Lomb Incorporated | UV curable crosslinking agents useful in copolymerization |
| US5358995A (en) | 1992-05-15 | 1994-10-25 | Bausch & Lomb Incorporated | Surface wettable silicone hydrogels |
| US5260000A (en) | 1992-08-03 | 1993-11-09 | Bausch & Lomb Incorporated | Process for making silicone containing hydrogel lenses |
| US5321108A (en) | 1993-02-12 | 1994-06-14 | Bausch & Lomb Incorporated | Fluorosilicone hydrogels |
| US5616757A (en) | 1993-04-08 | 1997-04-01 | Bausch & Lomb Incorporated | Organosilicon-containing materials useful for biomedical devices |
| US5760100B1 (en) | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
| BR9612119A (pt) | 1995-12-07 | 1999-02-17 | Bausch & Lomb | Unidade monomérica composição de hidrogel lente de contato e método para produzir uma composição de hidrogel |
| US5714557A (en) | 1995-12-07 | 1998-02-03 | Bausch & Lomb Incorporated | Monomeric units useful for reducing the modulus of low water polymeric silicone compositions |
| US5708094A (en) | 1996-12-17 | 1998-01-13 | Bausch & Lomb Incorporated | Polybutadiene-based compositions for contact lenses |
| CN1299387A (zh) | 1998-05-05 | 2001-06-13 | 博士伦公司 | 硅氧烷水凝胶接触镜片的等离子体表面处理 |
| US6550915B1 (en) | 1998-12-21 | 2003-04-22 | Bausch & Lomb Incorporated | Surface treatment of fluorinated contact lens materials |
| US6200626B1 (en) * | 1999-05-20 | 2001-03-13 | Bausch & Lomb Incorporated | Surface-treatment of silicone medical devices comprising an intermediate carbon coating and graft polymerization |
| US6630243B2 (en) * | 1999-05-20 | 2003-10-07 | Bausch & Lomb Incorporated | Surface treatment of silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating |
| US6213604B1 (en) | 1999-05-20 | 2001-04-10 | Bausch & Lomb Incorporated | Plasma surface treatment of silicone hydrogel contact lenses with a flexible carbon coating |
| CN1313842C (zh) * | 1999-10-12 | 2007-05-02 | 庄臣及庄臣视力保护公司 | 接触透镜涂层选择及其制造工艺 |
| US6599559B1 (en) | 2000-04-03 | 2003-07-29 | Bausch & Lomb Incorporated | Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers |
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| US6891010B2 (en) | 2001-10-29 | 2005-05-10 | Bausch & Lomb Incorporated | Silicone hydrogels based on vinyl carbonate endcapped fluorinated side chain polysiloxanes |
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| JP2004339165A (ja) * | 2003-05-16 | 2004-12-02 | Asahi Kasei Corp | 医療用具用コート材およびこれを用いた白血球除去フィルター |
| WO2005068571A1 (ja) * | 2004-01-15 | 2005-07-28 | Menicon Co., Ltd. | 眼用レンズ表面のコーティング剤 |
| WO2007024500A1 (en) * | 2005-08-25 | 2007-03-01 | Medtronic Vascular, Inc. | Controlled radical polymerization-derived block copolymer compositions for medical device coatings |
| US20070122540A1 (en) * | 2005-11-29 | 2007-05-31 | Bausch & Lomb Incorporated | Coatings on ophthalmic lenses |
| US7811555B2 (en) * | 2005-12-30 | 2010-10-12 | Cordis Corporation | Tri-branched biologically active copolymer |
| JP4832910B2 (ja) * | 2006-01-31 | 2011-12-07 | 株式会社メニコン | 眼用レンズ表面用コーティング剤およびそれにより得られる眼用レンズ |
-
2008
- 2008-12-16 EP EP13151482.0A patent/EP2597113A1/en not_active Withdrawn
- 2008-12-16 EP EP08868283A patent/EP2235094A1/en not_active Withdrawn
- 2008-12-16 WO PCT/US2008/086989 patent/WO2009085755A1/en not_active Ceased
- 2008-12-16 CN CN2008801271893A patent/CN101977972B/zh not_active Expired - Fee Related
- 2008-12-16 JP JP2010540781A patent/JP2011508059A/ja active Pending
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