JP2011504101A5 - - Google Patents

Download PDF

Info

Publication number
JP2011504101A5
JP2011504101A5 JP2010533264A JP2010533264A JP2011504101A5 JP 2011504101 A5 JP2011504101 A5 JP 2011504101A5 JP 2010533264 A JP2010533264 A JP 2010533264A JP 2010533264 A JP2010533264 A JP 2010533264A JP 2011504101 A5 JP2011504101 A5 JP 2011504101A5
Authority
JP
Japan
Prior art keywords
cells
cell
population
cancer
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010533264A
Other languages
English (en)
Japanese (ja)
Other versions
JP6230208B2 (ja
JP2011504101A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/082750 external-priority patent/WO2009062001A1/en
Publication of JP2011504101A publication Critical patent/JP2011504101A/ja
Publication of JP2011504101A5 publication Critical patent/JP2011504101A5/ja
Application granted granted Critical
Publication of JP6230208B2 publication Critical patent/JP6230208B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010533264A 2007-11-08 2008-11-07 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激 Expired - Fee Related JP6230208B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US253807P 2007-11-08 2007-11-08
US61/002,538 2007-11-08
PCT/US2008/082750 WO2009062001A1 (en) 2007-11-08 2008-11-07 Stimulation of anti-tumor immunity using dendritic cell/tumor cell fusions and anti-cd3/cd28

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2015135162A Division JP2015171389A (ja) 2007-11-08 2015-07-06 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激
JP2017125187A Division JP2017200486A (ja) 2007-11-08 2017-06-27 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激

Publications (3)

Publication Number Publication Date
JP2011504101A JP2011504101A (ja) 2011-02-03
JP2011504101A5 true JP2011504101A5 (enExample) 2012-11-22
JP6230208B2 JP6230208B2 (ja) 2017-11-15

Family

ID=40451354

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010533264A Expired - Fee Related JP6230208B2 (ja) 2007-11-08 2008-11-07 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激
JP2015135162A Pending JP2015171389A (ja) 2007-11-08 2015-07-06 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激
JP2017125187A Pending JP2017200486A (ja) 2007-11-08 2017-06-27 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015135162A Pending JP2015171389A (ja) 2007-11-08 2015-07-06 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激
JP2017125187A Pending JP2017200486A (ja) 2007-11-08 2017-06-27 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激

Country Status (6)

Country Link
US (1) US20100278873A1 (enExample)
EP (2) EP3375868A1 (enExample)
JP (3) JP6230208B2 (enExample)
AU (1) AU2008323853B8 (enExample)
CA (1) CA2704232C (enExample)
WO (1) WO2009062001A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017143985A (ru) 2011-08-17 2019-02-14 Глоубиммьюн, Инк. Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения
EP2912069B1 (en) * 2012-10-23 2019-07-31 Emory University Gm-csf and il-4 conjugates, compositions, and methods related thereto
CN103911341B (zh) * 2014-01-26 2016-04-13 山东迪博生物科技股份有限公司 Th1细胞亚群的制备方法及其在制备抗肿瘤细胞制剂中的应用
MX374472B (es) 2014-03-20 2025-03-06 H Lee Moffitt Cancer Ct & Res Composiciones y métodos para mejorar los linfocitos infiltrantes de tumor para terapia celular adoptiva.
WO2016145578A1 (en) 2015-03-13 2016-09-22 Syz Cell Therapy Co. Methods of cancer treatment using activated t cells
US11026921B2 (en) * 2015-03-30 2021-06-08 Dana-Farber Cancer Institute, Inc. Compositions and methods of treating cancer
AU2016243194A1 (en) * 2015-03-30 2017-09-21 Beth Israel Deaconess Medical Center Compositions and methods of treating acute myeloid leukemia
CA2977749A1 (en) * 2015-03-30 2016-10-06 Dana-Farber Cancer Institute, Inc. Compositions and methods of treating renal cell cancer
WO2016198470A2 (en) * 2015-06-08 2016-12-15 Lophius Biosciences Gmbh Composition for determination of cell-mediated immune responsiveness
CN114774356A (zh) 2015-06-30 2022-07-22 西北生物治疗药物公司 诱发改善的或增加的抗肿瘤免疫应答的经最佳活化的树突细胞
WO2017151855A1 (en) * 2016-03-03 2017-09-08 Mayo Foundation For Medical Education And Research Materials and methods for increasing immune responses
US20190125848A1 (en) * 2016-03-30 2019-05-02 Dana-Farber Cancer Institute, Inc. Dendritic cell-extracellular vesicle fusions and methods of using same
CA3019574C (en) * 2016-03-31 2025-09-23 Sanbio Inc Medium, methods, cells and secreted factors for stem cell culture and therapy
CN106434556B (zh) 2016-11-22 2019-10-11 上海新长安生物科技有限公司 一种体外诱导扩增i型nkt细胞的方法
AU2018207430A1 (en) * 2017-01-11 2019-07-04 Dana-Farber Cancer Institute, Inc. Personalized vaccines
CN106834228B (zh) * 2017-01-17 2021-03-23 上海新长安生物科技有限公司 一种体外扩增cd8+t细胞及其细胞亚群的方法
WO2018147291A1 (en) * 2017-02-07 2018-08-16 Saitama Medical University Immunological biomarker for predicting clinical effect of cancer immunotherapy
WO2019183924A1 (en) 2018-03-30 2019-10-03 Syz Cell Therapy Co. Improved multiple antigen specific cell therapy methods
WO2019196087A1 (en) 2018-04-13 2019-10-17 Syz Cell Therapy Co. Methods of cancer treatment using tumor antigen-specific t cells
WO2019196088A1 (en) 2018-04-13 2019-10-17 Syz Cell Therapy Co. Methods of obtaining tumor-specific t cell receptors
WO2020061203A1 (en) 2018-09-21 2020-03-26 Nantcell, Inc. Methods and compositions for modulating myeloid-derived suppressor cells
JP7606225B2 (ja) 2019-02-20 2024-12-25 学校法人 埼玉医科大学 放射線治療による抗腫瘍免疫効果を評価する末梢血バイオマーカー
CN112430575B (zh) * 2019-08-26 2024-01-19 深圳市菲鹏生物治疗股份有限公司 通用型car-t细胞及其制备方法、应用以及抗肿瘤药物
CN111286486A (zh) * 2019-12-19 2020-06-16 清华大学 体外大量扩增恶性肿瘤腹水浸润的淋巴细胞的方法
US20230236172A1 (en) * 2020-03-20 2023-07-27 Nantcell, Inc. T Cells That Respond To Patient Neoepitopes
KR102607909B1 (ko) 2020-08-19 2023-12-01 젠코어 인코포레이티드 항-cd28 조성물
CN114317445B (zh) * 2020-09-30 2025-07-25 广东东阳光药业股份有限公司 扩增t细胞的方法及其应用
CN112725402A (zh) * 2021-01-22 2021-04-30 华夏源细胞工程集团股份有限公司 一种检测人羊膜上皮细胞体外抑制淋巴细胞增殖抑制方法
EP4319800A1 (en) 2021-04-07 2024-02-14 Dana-Farber Cancer Institute, Inc. Compositions and methods for the treatment of cancer
CN119110809A (zh) 2022-02-23 2024-12-10 Xencor股份有限公司 抗CD28 x抗PSMA抗体
WO2024026505A2 (en) * 2022-07-29 2024-02-01 Amit Patel Disruption of telocyte activity
CN115747159A (zh) * 2022-12-01 2023-03-07 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 一种用于杀伤肿瘤的肿瘤相关淋巴结t细胞及其制备方法和应用
CN117122675A (zh) * 2023-09-28 2023-11-28 上海恒赛生物科技有限公司 一种用于透明细胞肾细胞癌的树突状细胞疫苗及其应用、制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858358A (en) * 1992-04-07 1999-01-12 The United States Of America As Represented By The Secretary Of The Navy Methods for selectively stimulating proliferation of T cells
DE69131908T3 (de) 1991-02-19 2008-04-03 Oxford Biomedica (Uk) Ltd. Viruspartikel mit veraendertem wirtspektrum
WO1993014188A1 (en) 1992-01-17 1993-07-22 The Regents Of The University Of Michigan Targeted virus
JP3532566B2 (ja) 1993-06-24 2004-05-31 エル. グラハム,フランク 遺伝子治療のためのアデノウイルスベクター
JP3875990B2 (ja) 1993-10-25 2007-01-31 カンジ,インコーポレイテッド 組換えアデノウイルスベクターおよび使用方法
US7252989B1 (en) 1994-04-04 2007-08-07 Board Of Regents, The University Of Texas System Adenovirus supervector system
US5643786A (en) 1995-01-27 1997-07-01 The United States Of America As Represented By The Department Of Health And Human Services Method for isolating dendritic cells
AUPN568095A0 (en) * 1995-09-27 1995-10-26 Austin Research Institute, The Anti-Galalpha(1,3)Gal antibody binding peptides
US20050170503A1 (en) * 1997-02-27 2005-08-04 University Of Pittsburgh In vitro induction of antigen-specific T-cells using dendritic cell-tumor cell or dendritic cell-viral cell derived immunogens
US20020041868A1 (en) * 1997-04-15 2002-04-11 Charles Nicolette Cell fusions and methods of making and using the same
DK1248836T3 (da) * 2000-01-11 2005-08-15 Greenville Hospital System Fremgangsmåde til fremstilling af vacciner ved anvendelse af hybridceller
JP5054875B2 (ja) * 2000-02-11 2012-10-24 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 樹状細胞ハイブリッドによって活性化される細胞傷害性tリンパ球
DE10041515A1 (de) * 2000-08-24 2002-03-14 Gerold Schuler Verfahren zur Herstellung gebrauchsfertiger, Antigen-beladener oder -unbeladener, kryokonservierter reifer dendritischer Zellen
US6614237B2 (en) 2000-09-18 2003-09-02 Agilent Technologies, Inc. Multiport automatic calibration device for a multiport test system
US20030082806A1 (en) * 2001-04-27 2003-05-01 Xcyte Therapies, Inc. Maturation of antigen-presenting cells using activated T cells
CN100528230C (zh) * 2003-02-19 2009-08-19 台桂香 重组人muc1-mbp融合蛋白抗肿瘤疫苗及生产工艺
US8110194B2 (en) * 2005-12-07 2012-02-07 Medarex, Inc. CTLA-4 antibody dosage escalation regimens

Similar Documents

Publication Publication Date Title
JP6230208B2 (ja) 樹状細胞/腫瘍細胞融合物および抗cd3/cd28を使用する抗腫瘍免疫の刺激
JP2011504101A5 (enExample)
JP2022065022A (ja) 改変ヒト初代血液樹状細胞株を生成するための方法
AU2016243629B2 (en) Compositions and methods of treating cancer
JP2018531022A6 (ja) 改変ヒト初代血液樹状細胞株を生成するための方法
CA2977836A1 (en) Compositions and methods of treating cancer
Toujas et al. Human monocyte‐derived macrophages and dendritic cells are comparably effective in vitro in presenting HLA class I‐restricted exogenous peptides
US20210317410A1 (en) Methods of making natural killer cells and uses thereof
US20090175890A1 (en) Use of immature dendritic cells to silence antigen specific cd8+ t cell function
AU2017240584A1 (en) Dendritic cell- extracellular vesicle fusions and methods of using same
AU2016243626A1 (en) Compositions and methods of treating multiple myeloma
JP5054875B2 (ja) 樹状細胞ハイブリッドによって活性化される細胞傷害性tリンパ球
AU2016243194A1 (en) Compositions and methods of treating acute myeloid leukemia
JP2003521936A5 (enExample)
CA3042944A1 (en) Compositions and methods of treating cancer
US20200000896A1 (en) Compositions and methods of treating cancer
WO1999046984A1 (en) Compositions and methods for the frozen storage of dendritic cells
Clayton Cultured Dendritic Cells for Cancer Immunotherapy