JP2011500588A5 - - Google Patents
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- Publication number
- JP2011500588A5 JP2011500588A5 JP2010529062A JP2010529062A JP2011500588A5 JP 2011500588 A5 JP2011500588 A5 JP 2011500588A5 JP 2010529062 A JP2010529062 A JP 2010529062A JP 2010529062 A JP2010529062 A JP 2010529062A JP 2011500588 A5 JP2011500588 A5 JP 2011500588A5
- Authority
- JP
- Japan
- Prior art keywords
- agents
- excipients
- abt
- propellants
- humectants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000006082 mold release agent Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- JNAHVYVRKWKWKQ-CYBMUJFWSA-N veliparib Chemical compound N=1C2=CC=CC(C(N)=O)=C2NC=1[C@@]1(C)CCCN1 JNAHVYVRKWKWKQ-CYBMUJFWSA-N 0.000 description 1
- 229950011257 veliparib Drugs 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97965407P | 2007-10-12 | 2007-10-12 | |
| PCT/US2008/079439 WO2009049109A1 (en) | 2007-10-12 | 2008-10-10 | 2-((r)-2-methylpyrrolidin-2-yl)-1h-benzimidazole-4-carboxamide crystalline form 2 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014142419A Division JP2014237660A (ja) | 2007-10-12 | 2014-07-10 | ２−（（ｒ）−２−メチルピロリジン−２−イル）−１ｈ−ベンズイミダゾール−４−カルボキサミド結晶型２ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500588A JP2011500588A (ja) | 2011-01-06 |
| JP2011500588A5 true JP2011500588A5 (enExample) | 2014-03-27 |
Family
ID=40279000
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529062A Pending JP2011500588A (ja) | 2007-10-12 | 2008-10-10 | ２−（（ｒ）−２−メチルピロリジン−２−イル）−１ｈ−ベンズイミダゾール−４−カルボキサミド結晶型２ |
| JP2014142419A Pending JP2014237660A (ja) | 2007-10-12 | 2014-07-10 | ２−（（ｒ）−２−メチルピロリジン−２−イル）−１ｈ−ベンズイミダゾール−４−カルボキサミド結晶型２ |
| JP2016220205A Pending JP2017071617A (ja) | 2007-10-12 | 2016-11-11 | ２−（（ｒ）−２−メチルピロリジン−２−イル）−１ｈ−ベンズイミダゾール−４−カルボキサミド結晶型２ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014142419A Pending JP2014237660A (ja) | 2007-10-12 | 2014-07-10 | ２−（（ｒ）−２−メチルピロリジン−２−イル）−１ｈ−ベンズイミダゾール−４−カルボキサミド結晶型２ |
| JP2016220205A Pending JP2017071617A (ja) | 2007-10-12 | 2016-11-11 | ２−（（ｒ）−２−メチルピロリジン−２−イル）−１ｈ−ベンズイミダゾール−４−カルボキサミド結晶型２ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8013168B2 (enExample) |
| EP (2) | EP2727921B1 (enExample) |
| JP (3) | JP2011500588A (enExample) |
| CN (2) | CN101821269B (enExample) |
| CA (1) | CA2696423A1 (enExample) |
| ES (1) | ES2562081T3 (enExample) |
| MX (1) | MX2010003771A (enExample) |
| WO (1) | WO2009049109A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100090769A (ko) * | 2007-10-12 | 2010-08-17 | 아보트 러보러터리즈 | 2-((ｒ)-2-메틸피롤리딘-2-일)-1ｈ-벤즈이미다졸-4-카복스아미드 결정형 1 |
| AU2012243132A1 (en) * | 2011-04-11 | 2013-10-24 | Abbvie Inc. | PARP inhibitors for the treatment of CIPN |
| CN105130961B (zh) * | 2015-08-06 | 2018-02-16 | 苏州晶云药物科技有限公司 | Abt‑888的晶型b及其制备方法和应用 |
| CN106995436A (zh) * | 2016-01-25 | 2017-08-01 | 重庆医药工业研究院有限责任公司 | 一种维利帕尼晶型a及其制备方法 |
| US20190092756A1 (en) * | 2016-03-09 | 2019-03-28 | Crystal Pharmatech Co., Ltd. | Crystalline form a of 2-[(2r)-2-methyl-2-pyrrolidyl]-1h-benzimidazole-7-carboxamide dihydrochloride and preparation method thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1184208C (zh) * | 1998-11-27 | 2005-01-12 | 巴斯福股份公司 | 取代的苯并咪唑及其制备和用途 |
| SK9742002A3 (en) * | 2000-01-07 | 2003-02-04 | Transform Pharmaceuticals Inc | High-throughput formation, identification, and analysis of diverse solid-forms |
| DE10021468A1 (de) * | 2000-05-04 | 2001-11-08 | Basf Ag | Verwendung von PARP-Inhibitoren in kosmetischen Zubereitungen |
| CN1926127A (zh) * | 2003-12-29 | 2007-03-07 | 万有制药株式会社 | 新的2－杂芳基取代苯并咪唑衍生物 |
| TWI375673B (en) * | 2005-04-11 | 2012-11-01 | Abbott Lab | 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors |
| KR20100090769A (ko) | 2007-10-12 | 2010-08-17 | 아보트 러보러터리즈 | 2-((ｒ)-2-메틸피롤리딘-2-일)-1ｈ-벤즈이미다졸-4-카복스아미드 결정형 1 |
-
2008
- 2008-10-10 CA CA2696423A patent/CA2696423A1/en not_active Abandoned
- 2008-10-10 JP JP2010529062A patent/JP2011500588A/ja active Pending
- 2008-10-10 MX MX2010003771A patent/MX2010003771A/es active IP Right Grant
- 2008-10-10 US US12/248,988 patent/US8013168B2/en active Active
- 2008-10-10 EP EP14153258.0A patent/EP2727921B1/en active Active
- 2008-10-10 CN CN200880111585.7A patent/CN101821269B/zh not_active Expired - Fee Related
- 2008-10-10 ES ES08837011.9T patent/ES2562081T3/es active Active
- 2008-10-10 CN CN201410190297.2A patent/CN104230893A/zh active Pending
- 2008-10-10 WO PCT/US2008/079439 patent/WO2009049109A1/en not_active Ceased
- 2008-10-10 EP EP08837011.9A patent/EP2217603B1/en active Active
-
2014
- 2014-07-10 JP JP2014142419A patent/JP2014237660A/ja active Pending
-
2016
- 2016-11-11 JP JP2016220205A patent/JP2017071617A/ja active Pending
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