JP2011500514A5 - - Google Patents
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- Publication number
- JP2011500514A5 JP2011500514A5 JP2010528244A JP2010528244A JP2011500514A5 JP 2011500514 A5 JP2011500514 A5 JP 2011500514A5 JP 2010528244 A JP2010528244 A JP 2010528244A JP 2010528244 A JP2010528244 A JP 2010528244A JP 2011500514 A5 JP2011500514 A5 JP 2011500514A5
- Authority
- JP
- Japan
- Prior art keywords
- subtype
- pandemic
- influenza
- immunogen
- adjuvant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002163 immunogen Effects 0.000 claims 8
- 230000000240 adjuvant Effects 0.000 claims 4
- 239000002671 adjuvant Substances 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 230000003308 immunostimulating Effects 0.000 claims 4
- 241000712461 unidentified influenza virus Species 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 3
- 200000000003 influenza A Diseases 0.000 claims 3
- 230000001681 protective Effects 0.000 claims 3
- 241001473385 H5N1 subtype Species 0.000 claims 2
- 208000006572 Human Influenza Diseases 0.000 claims 2
- 206010022000 Influenza Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 241001473004 H10N7 subtype Species 0.000 claims 1
- 241000197306 H1N1 subtype Species 0.000 claims 1
- 241000252870 H3N2 subtype Species 0.000 claims 1
- 241000252863 H7N3 subtype Species 0.000 claims 1
- 241000252868 H7N7 subtype Species 0.000 claims 1
- 241001473386 H9N2 subtype Species 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000003904 phospholipids Chemical class 0.000 claims 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims 1
- 150000007949 saponins Chemical class 0.000 claims 1
- 150000003432 sterols Chemical class 0.000 claims 1
- 235000003702 sterols Nutrition 0.000 claims 1
- 230000004936 stimulating Effects 0.000 claims 1
Claims (8)
- (i)地域流行性インフルエンザ亜型の免疫原の少なくとも1つ、および
(ii)アジュバントとして、免疫原を含まない免疫刺激複合体、
を含む組成物である、対象において汎発流行性亜型のインフルエンザウィルスに対する保護免疫応答を惹起または誘導するための薬剤。 - 地域流行性インフルエンザA H1N1および/またはH3N2亜型の免疫原を含む、請求項1記載の薬剤。
- 免疫原を含まない免疫刺激複合体が、サポニン、ステロール、および任意にリン脂質を含む、請求項1または2に記載の薬剤。
- 免疫原を含まない免疫刺激複合体が、ISCOMATRIXTMアジュバントを含む、請求項3に記載の薬剤。
- 汎発流行性亜型インフルエンザウィルスが、インフルエンザA H5N1、H7N7、H7N3、H9N2、およびH10N7亜型から選択される、請求項1〜4のいずれか一項に記載の薬剤。
- 前記汎発流行性亜型がインフルエンザA H5N1亜型である、請求項5に記載の薬剤。
- 汎発流行性亜型のインフルエンザウィルスに対する保護免疫応答を惹起または誘導するために対象に投与するための薬剤の製造における、
(i)地域流行性インフルエンザ亜型の免疫原の少なくとも1つ、および
(ii)アジュバントとして、免疫原を含まない免疫刺激複合体
を含む組成物の使用。 - 汎発流行性亜型インフルエンザウィルスに対する保護免疫応答を惹起または誘導するための
(i)地域流行性インフルエンザ亜型の免疫原の少なくとも1つ、および
(ii)アジュバントとして、免疫原を含まない免疫刺激複合体
を含む組成物の使用。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97957207P | 2007-10-12 | 2007-10-12 | |
PCT/AU2008/001500 WO2009046497A1 (en) | 2007-10-12 | 2008-10-09 | Method of eliciting an immune response against pandemic influenza virus |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2011500514A JP2011500514A (ja) | 2011-01-06 |
JP2011500514A5 true JP2011500514A5 (ja) | 2011-11-17 |
Family
ID=40548886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010528244A Pending JP2011500514A (ja) | 2007-10-12 | 2008-10-09 | 汎発流行性インフルエンザウィルスに対する免疫応答を惹起する方法 |
Country Status (10)
Country | Link |
---|---|
US (1) | US8999353B2 (ja) |
EP (1) | EP2195019A4 (ja) |
JP (1) | JP2011500514A (ja) |
KR (1) | KR20100082825A (ja) |
CN (1) | CN101820904A (ja) |
AU (1) | AU2008310312B2 (ja) |
CA (1) | CA2700937C (ja) |
NZ (1) | NZ583377A (ja) |
SG (1) | SG185294A1 (ja) |
WO (1) | WO2009046497A1 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2805741C (en) | 2010-07-23 | 2019-08-13 | Karin Bengtsson Loevgren | Composition including an iscom matrix and ectodomains |
US9524531B2 (en) * | 2011-05-09 | 2016-12-20 | Microsoft Technology Licensing, Llc | Extensibility features for electronic communications |
EP2750683B2 (en) * | 2011-10-03 | 2021-01-06 | Croda International PLC | Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrophobic molecules in fields of medicine including cancer treatment and food related compounds |
BR112020019108A2 (pt) * | 2018-03-19 | 2020-12-29 | Novavax, Inc. | Vacinas polivalentes de nanopartículas de influenza |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2323733A1 (en) | 1998-04-13 | 1999-10-21 | Michael B. Brenner | Vaccine compositions comprising cd-1 antigens and t-cell stimulating compound and methods of use thereof |
AU783344B2 (en) | 1999-02-17 | 2005-10-20 | Csl Limited | Immunogenic complexes and methods relating thereto |
NZ518401A (en) | 1999-10-29 | 2004-01-30 | Nektar Therapeutics | Dry powder compositions having improved dispersivity |
CA2391843C (en) | 1999-11-19 | 2011-10-18 | Csl Limited | Hcv vaccine compositions |
AU2001251316A1 (en) | 2000-04-04 | 2001-10-15 | Antigenics Inc. | Isolated and purified nonpeptide antigens from mycobacterium tuberculosis |
MXPA02012501A (es) | 2000-06-16 | 2003-06-06 | Sembiosys Genetics Inc | El uso de cuerpos grasos vegetales en sistemas de administracion de vacunas. |
GB0021757D0 (en) | 2000-09-04 | 2000-10-18 | Colaco Camilo | Vaccine against microbial pathogens |
JP5153990B2 (ja) | 2001-12-21 | 2013-02-27 | シーエスエル、リミテッド | 免疫反応性試薬およびサポニンを含有する組成物、およびその使用方法 |
US20030190333A1 (en) | 2002-02-04 | 2003-10-09 | Corixa Corporation | Immunostimulant compositions comprising aminoalkyl glucosaminide phosphates and saponins |
GB0401239D0 (en) | 2004-01-21 | 2004-02-25 | Molecularnature Ltd | Adjuvant compositions |
AU2005244128B2 (en) | 2004-05-07 | 2009-06-25 | President And Fellows Of Harvard College | Pulmonary malarial vaccine |
CA2572427A1 (en) | 2004-07-18 | 2006-01-18 | Heather L. Davis | Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses |
US20070190072A1 (en) | 2004-09-30 | 2007-08-16 | Csl Limited Ludwig Institute For Cancer Research | In vivo efficacy of ny-eso-1 plus adjuvant |
AU2006226458B2 (en) | 2005-03-23 | 2012-08-30 | Glaxosmithkline Biologicals S.A. | Novel composition |
WO2008025095A1 (en) * | 2006-09-01 | 2008-03-06 | Csl Limited | Method of eliciting or inducing an immune response |
-
2008
- 2008-10-09 EP EP08800134A patent/EP2195019A4/en not_active Withdrawn
- 2008-10-09 NZ NZ583377A patent/NZ583377A/xx unknown
- 2008-10-09 KR KR1020107005929A patent/KR20100082825A/ko not_active Application Discontinuation
- 2008-10-09 AU AU2008310312A patent/AU2008310312B2/en active Active
- 2008-10-09 SG SG2012075776A patent/SG185294A1/en unknown
- 2008-10-09 JP JP2010528244A patent/JP2011500514A/ja active Pending
- 2008-10-09 CN CN200880111106A patent/CN101820904A/zh active Pending
- 2008-10-09 US US12/679,654 patent/US8999353B2/en active Active
- 2008-10-09 WO PCT/AU2008/001500 patent/WO2009046497A1/en active Application Filing
- 2008-10-09 CA CA2700937A patent/CA2700937C/en active Active
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