JP2011251985A5 - - Google Patents

Download PDF

Info

Publication number
JP2011251985A5
JP2011251985A5 JP2011157930A JP2011157930A JP2011251985A5 JP 2011251985 A5 JP2011251985 A5 JP 2011251985A5 JP 2011157930 A JP2011157930 A JP 2011157930A JP 2011157930 A JP2011157930 A JP 2011157930A JP 2011251985 A5 JP2011251985 A5 JP 2011251985A5
Authority
JP
Japan
Prior art keywords
hydrate
pharmaceutically acceptable
acceptable salt
hydroxamic acid
batch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011157930A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011251985A (ja
JP5308486B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2011251985A publication Critical patent/JP2011251985A/ja
Publication of JP2011251985A5 publication Critical patent/JP2011251985A5/ja
Application granted granted Critical
Publication of JP5308486B2 publication Critical patent/JP5308486B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011157930A 2005-05-20 2011-07-19 スベロイルアニリドヒドロキサム酸の製剤及びこれを作製するための方法 Active JP5308486B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68287505P 2005-05-20 2005-05-20
US60/682,875 2005-05-20
US69312805P 2005-06-23 2005-06-23
US60/693,128 2005-06-23

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007540436A Division JP5264174B2 (ja) 2005-05-20 2006-05-16 スベロイルアニリドヒドロキサム酸の製剤及びこれを作製するための方法

Publications (3)

Publication Number Publication Date
JP2011251985A JP2011251985A (ja) 2011-12-15
JP2011251985A5 true JP2011251985A5 (OSRAM) 2012-10-04
JP5308486B2 JP5308486B2 (ja) 2013-10-09

Family

ID=37452585

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007540436A Active JP5264174B2 (ja) 2005-05-20 2006-05-16 スベロイルアニリドヒドロキサム酸の製剤及びこれを作製するための方法
JP2011157930A Active JP5308486B2 (ja) 2005-05-20 2011-07-19 スベロイルアニリドヒドロキサム酸の製剤及びこれを作製するための方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2007540436A Active JP5264174B2 (ja) 2005-05-20 2006-05-16 スベロイルアニリドヒドロキサム酸の製剤及びこれを作製するための方法

Country Status (20)

Country Link
US (4) US8093295B2 (OSRAM)
EP (2) EP1853245A2 (OSRAM)
JP (2) JP5264174B2 (OSRAM)
KR (2) KR100884500B1 (OSRAM)
AR (1) AR055953A1 (OSRAM)
AU (3) AU2006249440C1 (OSRAM)
BR (1) BRPI0605893A (OSRAM)
CA (1) CA2580367C (OSRAM)
CR (1) CR8912A (OSRAM)
DO (1) DOP2006000113A (OSRAM)
EC (1) ECSP077263A (OSRAM)
IL (1) IL181070A0 (OSRAM)
MA (1) MA28804B1 (OSRAM)
MX (1) MX2007002047A (OSRAM)
MY (1) MY144613A (OSRAM)
NI (1) NI200700031A (OSRAM)
NZ (2) NZ553204A (OSRAM)
PE (1) PE20061390A1 (OSRAM)
TW (2) TWI415603B (OSRAM)
WO (2) WO2006127321A2 (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI415603B (zh) * 2005-05-20 2013-11-21 Merck Sharp & Dohme 1,8-辛二醯基苯胺羥胺酸(suberoylanilide hydroxamic acid)之調配物及其製配方法
AU2009305214B2 (en) 2008-10-15 2015-06-25 Generics [Uk] Limited Process for the preparation of vorinostat
NZ593585A (en) * 2008-11-26 2012-12-21 Generics Uk Ltd Crystalline forms of vorinostat (suberoylanilide hydroxamic acid)
EP2362870A2 (en) * 2008-11-26 2011-09-07 Generics [UK] Limited Novel processes and pure polymorphs
US20110313044A1 (en) * 2010-06-18 2011-12-22 Urquima S.A. Polymorphs of Suberoylanilide Hydroxamic Acid
WO2018011811A2 (en) * 2016-07-13 2018-01-18 Rappaport Family Institute For Research In The Medical Sciences Inhibitors of cytoplasmic histone deacetylase 4 complex for treating or preventing vascular or valve calcification
CN107362148B (zh) * 2017-07-27 2020-04-21 东曜药业有限公司 一种治疗肿瘤的药物组合物及其制备方法和应用
EP4007585A4 (en) 2019-08-02 2023-11-08 OneHealthCompany, Inc. TREATMENT OF CANINE CANCERS

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
JPS61176523A (ja) * 1985-01-30 1986-08-08 Teruhiko Beppu 制癌剤
US5608108A (en) * 1988-11-14 1997-03-04 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and method of use thereof
US5055608A (en) * 1988-11-14 1991-10-08 Sloan-Kettering Institute For Cancer Research Novel potent inducers of thermal differentiation and method of use thereof
US5175191A (en) * 1988-11-14 1992-12-29 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
USRE38506E1 (en) * 1991-10-04 2004-04-20 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
US5369108A (en) * 1991-10-04 1994-11-29 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
US5700811A (en) 1991-10-04 1997-12-23 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and method of use thereof
US5635532A (en) * 1991-10-21 1997-06-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Compositions and methods for therapy and prevention of pathologies including cancer, AIDS and anemia
JP3170069B2 (ja) * 1992-10-06 2001-05-28 日水製薬株式会社 徐放性顆粒剤
US6030961A (en) 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6043389A (en) * 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6124495A (en) 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6231880B1 (en) * 1997-05-30 2001-05-15 Susan P. Perrine Compositions and administration of compositions for the treatment of blood disorders
AUPO721997A0 (en) 1997-06-06 1997-07-03 Queensland Institute Of Medical Research, The Anticancer compounds
US6262116B1 (en) * 1998-01-23 2001-07-17 Sloan-Kettering Institute For Cancer Research Transcription therapy for cancers
IL142531A0 (en) 1998-10-13 2002-03-10 Fujisawa Pharmaceutical Co Cyclic peptide compound, processes for the preparation thereof and pharmaceutical compositions containing the same
JP2003500052A (ja) 1999-05-03 2003-01-07 メチルジーン インコーポレイテッド ヒストン脱アセチル酵素の抑制
JP2001081031A (ja) 1999-08-30 2001-03-27 Schering Ag 溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤
TR200201052T2 (tr) 1999-09-08 2003-01-21 Sloan-Kettering Institute For Cancer Research Yeni hücre farklılaştırıcı ajanlar sınıfı ve hıstone deacetylase inhibitörleri, ve burada kullanım yöntemleri
DK1233958T3 (da) 1999-11-23 2011-10-17 Methylgene Inc Hæmmere af histondeacetylase
WO2001070675A2 (en) 2000-03-24 2001-09-27 Methylgene, Inc. Inhibitors of histone deacetylase
WO2002015921A2 (en) 2000-08-18 2002-02-28 The Governement Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods of treating cutaneous and peripheral t-cell lymphoma by a histone deacetylase inhibitor
PE20020354A1 (es) 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
EP2292593A3 (en) 2000-09-29 2011-05-25 TopoTarget UK Limited Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
AU2002243231A1 (en) * 2000-11-21 2002-07-24 Wake Forest University Method of treating autoimmune diseases
AR035659A1 (es) 2000-12-07 2004-06-23 Hoffmann La Roche Hidroxiamidas de acido (1-oxo-1,2,3,4-tetrahidro-naftalen-2-il)-alcanoico, proceso para la manufactura de estos compuestos, composiciones farmaceuticas que contienen dichos compuestos y los usos de los mismos
US6495719B2 (en) * 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
EP1532244A4 (en) * 2001-06-14 2005-12-14 Bristol Myers Squibb Co NEW HISTONIC HUMAN DEACETYLASES
EP2269609A3 (en) * 2001-10-16 2012-07-11 Sloan-Kettering Institute for Cancer Research Treatment of neurodegenerative diseases and cancer of the brain with SAHA
US20040132643A1 (en) * 2002-01-09 2004-07-08 Fojo Antonio Tito Histone deacelylase inhibitors in diagnosis and treatment of thyroid neoplasms
WO2003070188A2 (en) * 2002-02-15 2003-08-28 Sloan-Kettering Institute For Cancer Research Method of treating trx mediated diseases
MXPA04008577A (es) * 2002-03-04 2005-07-13 Aton Pharma Inc Metodos para inducir diferenciacion terminal.
US20060276547A1 (en) * 2002-03-04 2006-12-07 Bacopoulos Nicholas G Methods of treating cancer with HDAC inhibitors
US7148257B2 (en) * 2002-03-04 2006-12-12 Merck Hdac Research, Llc Methods of treating mesothelioma with suberoylanilide hydroxamic acid
US20070060614A1 (en) * 2002-03-04 2007-03-15 Bacopoulos Nicholas G Methods of treating cancer with hdac inhibitors
US20040132825A1 (en) * 2002-03-04 2004-07-08 Bacopoulos Nicholas G. Methods of treating cancer with HDAC inhibitors
US7456219B2 (en) * 2002-03-04 2008-11-25 Merck Hdac Research, Llc Polymorphs of suberoylanilide hydroxamic acid
AU2003226408B2 (en) * 2002-04-15 2007-06-14 Sloan-Kettering Institute For Cancer Research Combination therapy for the treatment of cancer
DE10218106A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen von Arzneimittelwirkstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
EP1567142A4 (en) * 2002-11-20 2005-12-14 Errant Gene Therapeutics Llc TREATMENT OF PULMONARY CELLS WITH HISTONE DEACETYLASE INHIBITORS
CA2520611A1 (en) * 2003-04-01 2004-10-21 Memorial Sloan-Kettering Cancer Center Hydroxamic acid compounds and methods of use thereof
PL379887A1 (pl) * 2003-08-26 2006-11-27 Merck Hdac Research, Llc Sposób leczenia raka inhibitorami HDAC
TWI415603B (zh) * 2005-05-20 2013-11-21 Merck Sharp & Dohme 1,8-辛二醯基苯胺羥胺酸(suberoylanilide hydroxamic acid)之調配物及其製配方法
EP1933825A2 (en) 2005-08-18 2008-06-25 Merck and Co., Inc. Combination methods of saha and targretin for treating cancer
US20070117815A1 (en) 2005-11-04 2007-05-24 James Pluda Method of treating cancers with SAHA and pemetrexed
WO2007056162A2 (en) 2005-11-04 2007-05-18 Merck & Co., Inc. Methods of treating cancers with saha, carboplatin, and paclitaxel and other combination therapies
US20070197568A1 (en) * 2005-11-04 2007-08-23 Paul Bunn Methods of using SAHA and Erlotinib for treating cancer

Similar Documents

Publication Publication Date Title
JP2011251985A5 (OSRAM)
WO2013132457A3 (en) Nanocrystalline solid dispersion compositions and process of preparation thereof
CL2013000347A1 (es) Poblacion de microparticulas que comprenden un corticoesteroide clase b incorporado en una matriz formada por un copolimero de acido lactico y acido glicolico, donde dicho corticoesteroide comprende entre 22% a 28% de las microparticulas; preparacion de liberacion controlada; formulacion; y metodo de fabricacion.
JP2014515013A5 (OSRAM)
JP2013032389A5 (OSRAM)
JP2015145426A5 (OSRAM)
JP2013527475A5 (OSRAM)
JP2012067110A5 (OSRAM)
JP2012255026A5 (OSRAM)
JP2017537066A5 (OSRAM)
JP2014500861A5 (OSRAM)
JP2012132799A5 (OSRAM)
JP2015525757A5 (OSRAM)
JP2014167010A5 (OSRAM)
JP2016534081A5 (ja) ゾレドロン酸の増強された経口バイオアベイラビリティーを有する経口剤形を調製する方法
JP2013007118A5 (OSRAM)
JP2015526577A5 (OSRAM)
JP2014097964A5 (OSRAM)
TN2012000435A1 (en) Agomelatine hydrochloride hydrate and preparation thereof
JP2012087043A5 (ja) 微小針状構造物
CA2899024C (en) Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid
WO2012146980A3 (en) Preparation of fingolimod and its salts
JP2017505809A5 (OSRAM)
CR8912A (es) Formulaciones de acido hidroxamico suberoilanilida y procedimientos para la produccion de las mismas
JP2012051888A5 (OSRAM)