JP2011168588A5 - - Google Patents
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- JP2011168588A5 JP2011168588A5 JP2011026980A JP2011026980A JP2011168588A5 JP 2011168588 A5 JP2011168588 A5 JP 2011168588A5 JP 2011026980 A JP2011026980 A JP 2011026980A JP 2011026980 A JP2011026980 A JP 2011026980A JP 2011168588 A5 JP2011168588 A5 JP 2011168588A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- compound
- apoptosis inducer
- test compound
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011026980A JP5213972B2 (ja) | 2004-04-09 | 2011-02-10 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004115404 | 2004-04-09 | ||
| JP2004115404 | 2004-04-09 | ||
| JP2011026980A JP5213972B2 (ja) | 2004-04-09 | 2011-02-10 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006512126A Division JP4761389B2 (ja) | 2004-04-09 | 2005-04-08 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012046652A Division JP5390653B2 (ja) | 2004-04-09 | 2012-03-02 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011168588A JP2011168588A (ja) | 2011-09-01 |
| JP2011168588A5 true JP2011168588A5 (enExample) | 2012-04-19 |
| JP5213972B2 JP5213972B2 (ja) | 2013-06-19 |
Family
ID=35124844
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006512126A Expired - Fee Related JP4761389B2 (ja) | 2004-04-09 | 2005-04-08 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
| JP2011026980A Expired - Fee Related JP5213972B2 (ja) | 2004-04-09 | 2011-02-10 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
| JP2012046652A Expired - Fee Related JP5390653B2 (ja) | 2004-04-09 | 2012-03-02 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006512126A Expired - Fee Related JP4761389B2 (ja) | 2004-04-09 | 2005-04-08 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012046652A Expired - Fee Related JP5390653B2 (ja) | 2004-04-09 | 2012-03-02 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8193332B2 (enExample) |
| EP (4) | EP2520652B1 (enExample) |
| JP (3) | JP4761389B2 (enExample) |
| KR (1) | KR101234281B1 (enExample) |
| WO (1) | WO2005097189A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1625853B1 (en) | 2003-05-19 | 2015-07-08 | Genecare Research Institute Co., Ltd | Apoptosis inducer for cancer cell |
| JP4761389B2 (ja) | 2004-04-09 | 2011-08-31 | 株式会社ジーンケア研究所 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
| KR101330229B1 (ko) * | 2004-11-19 | 2013-11-15 | 가부시키가이샤 진케어켄큐쇼 | 암세포 특이적 세포증식 억제제 |
| US20090208938A1 (en) * | 2005-02-10 | 2009-08-20 | Centre National De La Recherche Scientifique | Use of the MCM8 Gene for the Preparation of a Pharmaceutical Composition |
| EP1915622A2 (en) * | 2005-07-29 | 2008-04-30 | Oncotherapy Science, Inc. | Screening and therapeutic method for nsclc targeting cdca1-kntc2 complex |
| GB0606096D0 (en) * | 2006-03-27 | 2006-05-03 | Cbmm Sa | Screening method |
| WO2008047574A1 (fr) * | 2006-09-28 | 2008-04-24 | Genecare Research Institute Co., Ltd. | Sensibilisateur pour agent anticancéreux |
| JP4940412B2 (ja) * | 2006-10-16 | 2012-05-30 | 財団法人ヒューマンサイエンス振興財団 | 抗癌性物質のスクリーニング方法 |
| AU2007313551A1 (en) * | 2006-10-17 | 2008-04-24 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
| TWI615403B (zh) * | 2007-02-21 | 2018-02-21 | 腫瘤療法 科學股份有限公司 | 表現腫瘤相關抗原之癌症的胜肽疫苗 |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| WO2010034487A2 (en) * | 2008-09-23 | 2010-04-01 | Silence Therapeutics Ag | Means for inhibiting the expression of orc-1 |
| WO2010045526A1 (en) * | 2008-10-17 | 2010-04-22 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Geminin inhibitors as tumor treatment |
| CN102307997B (zh) * | 2008-12-04 | 2018-03-30 | 库尔纳公司 | 通过抑制针对沉默调节蛋白1的天然反义转录物来治疗沉默调节蛋白1(sirt1)相关的疾病 |
| US20110319317A1 (en) * | 2009-03-04 | 2011-12-29 | Opko Curna, Llc | Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirt1 |
| US8268550B2 (en) * | 2009-06-26 | 2012-09-18 | Massachusetts Institute Of Technology | Compositions and methods for identification of PARP function, inhibitors, and activators |
| US20110097329A1 (en) | 2009-06-26 | 2011-04-28 | Massachusetts Institute Of Technology | Compositions and methods for treating cancer and modulating stress granule formation |
| US8435961B2 (en) * | 2009-06-26 | 2013-05-07 | Massachusetts Institute Of Technology | Methods and compositions for increasing the activity of inhibitory RNA |
| EP2985348B1 (en) * | 2009-07-24 | 2020-12-30 | CuRNA, Inc. | Treatment of sirtuin 6 (sirt6) related diseases by inhibition of natural antisense transcript to sirt6 |
| CA2790284C (en) | 2010-02-17 | 2019-01-08 | Takeda Pharmaceutical Company Limited | Thieno-pyrimidine compounds having cdc7 inhibitory activity |
| WO2011150418A2 (en) * | 2010-05-28 | 2011-12-01 | Case Western Reserve University | Compositions and methods for treating pathologies |
| WO2012090479A1 (en) * | 2010-12-28 | 2012-07-05 | Oncotherapy Science, Inc. | Mcm7 as a target gene for cancer therapy and diagnosis |
| AU2013234955A1 (en) | 2012-03-23 | 2014-11-13 | Dennis Brown | Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo |
| CA2877736C (en) | 2012-06-29 | 2021-12-07 | Celgene Corporation | Methods for determining drug efficacy using cereblon-associated proteins |
| US9512486B2 (en) * | 2012-08-06 | 2016-12-06 | The Institute Of Cancer Research: Royal Cancer Hospital | Materials, methods, and systems for treating cancer |
| TWI658049B (zh) | 2013-03-12 | 2019-05-01 | 腫瘤療法 科學股份有限公司 | Kntc2胜肽及含此胜肽之疫苗 |
| KR101623814B1 (ko) | 2014-02-21 | 2016-05-24 | 두산중공업 주식회사 | 수냉각 발전기의 분리형 냉각수 순환 구조 및 그에 따른 냉각 방법 |
| JP2015167527A (ja) * | 2014-03-07 | 2015-09-28 | 学校法人東京理科大学 | 標的タンパク質の量の低減のためのポリペプチド、単離された核酸、組み換えベクター、及び形質転換体 |
| US20170362593A1 (en) * | 2014-12-23 | 2017-12-21 | Centre National De La Recherche Scientifique | Use of rad18 inhibitors in the treatment of tumors |
| CN104673801B (zh) * | 2015-02-12 | 2018-09-11 | 中山大学附属第三医院 | 一种肝癌基因ndc80及其应用 |
| ES2911415T3 (es) | 2015-06-08 | 2022-05-19 | Arquer Diagnostics Ltd | Métodos y kits |
| WO2016198833A2 (en) | 2015-06-08 | 2016-12-15 | Arquer Diagnostics Limited | Methods |
| US20190218261A1 (en) * | 2016-09-13 | 2019-07-18 | The Jackson Laboratory | Targeted enhanced dna demethylation |
| WO2018079287A1 (ja) * | 2016-10-26 | 2018-05-03 | デンカ株式会社 | 変異型ヒトDNAポリメラーゼε |
| WO2019005754A1 (en) * | 2017-06-26 | 2019-01-03 | The Cleveland Clinic Foundation | TREATMENT AGAINST CANCER |
| EP3851528A4 (en) * | 2018-09-12 | 2023-12-06 | Institute for Basic Science | COMPOSITION FOR INDUCATING DEATH OF CELLS HAVING MUTATED GENE AND METHOD FOR INDUCATING DEATH OF CELLS HAVING MODIFIED GENE USING THE COMPOSITION |
| JP2022020872A (ja) * | 2020-06-01 | 2022-02-02 | 均 石井 | 抗がん剤。 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0923738A1 (en) * | 1996-06-11 | 1999-06-23 | Advanced Research & Technology Institute | Methods and compositions for the use of apurinic/apyrimidinic endonucleases |
| GB0004193D0 (en) * | 2000-02-22 | 2000-04-12 | Isis Innovation | A genetic determinant for malignant melanoma |
| WO2002009573A2 (en) * | 2000-07-31 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of endometrial cancer |
| KR100872437B1 (ko) | 2000-12-01 | 2008-12-05 | 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. | Rna 간섭을 매개하는 작은 rna 분자 |
| US7892730B2 (en) * | 2000-12-22 | 2011-02-22 | Sagres Discovery, Inc. | Compositions and methods for cancer |
| WO2002102981A2 (en) * | 2001-06-15 | 2002-12-27 | The Trustees Of Columbia University In The City Of New York | SIR2α-BASED THERAPEUTIC AND PROPHYLACTIC METHODS |
| US7514406B2 (en) * | 2001-11-27 | 2009-04-07 | Fred Hutchinson Cancer Research Center | Methods for inhibiting deacetylase activity |
| AU2003207708A1 (en) | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
| WO2003105891A2 (en) * | 2002-06-12 | 2003-12-24 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Use of hec1 antagonists in the treatment of proliferative disorders and cancer |
| AU2003299378A1 (en) * | 2002-10-11 | 2004-05-04 | Board Of Regents, The University Of Texas System | Method and compounds for inhibiting hec1 activity for the treatment of proliferative diseases |
| JP2006507841A (ja) * | 2002-11-14 | 2006-03-09 | ダーマコン, インコーポレイテッド | 機能的siRNAおよび超機能的siRNA |
| EP1620573A4 (en) * | 2003-04-15 | 2006-12-20 | Avalon Pharmaceuticals | DETERMINATION OF CANCER-ASSOCIATED GENES AND THERAPEUTIC OBJECTS USING MOLECULAR CYTOGENETIC PROCEDURES |
| WO2004094636A1 (en) | 2003-04-24 | 2004-11-04 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| EP1625853B1 (en) | 2003-05-19 | 2015-07-08 | Genecare Research Institute Co., Ltd | Apoptosis inducer for cancer cell |
| JP4761389B2 (ja) | 2004-04-09 | 2011-08-31 | 株式会社ジーンケア研究所 | 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤 |
| KR101330229B1 (ko) * | 2004-11-19 | 2013-11-15 | 가부시키가이샤 진케어켄큐쇼 | 암세포 특이적 세포증식 억제제 |
-
2005
- 2005-04-08 JP JP2006512126A patent/JP4761389B2/ja not_active Expired - Fee Related
- 2005-04-08 EP EP12005593.4A patent/EP2520652B1/en not_active Expired - Lifetime
- 2005-04-08 EP EP12003008.5A patent/EP2481802B1/en not_active Expired - Lifetime
- 2005-04-08 EP EP05728503A patent/EP1757306A4/en not_active Withdrawn
- 2005-04-08 EP EP12004228.8A patent/EP2495324B1/en not_active Expired - Lifetime
- 2005-04-08 US US11/547,770 patent/US8193332B2/en not_active Expired - Fee Related
- 2005-04-08 WO PCT/JP2005/006914 patent/WO2005097189A1/ja not_active Ceased
- 2005-04-08 KR KR1020067023433A patent/KR101234281B1/ko not_active Expired - Fee Related
-
2011
- 2011-02-10 JP JP2011026980A patent/JP5213972B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-02 JP JP2012046652A patent/JP5390653B2/ja not_active Expired - Fee Related
- 2012-05-16 US US13/473,328 patent/US8470798B2/en not_active Expired - Fee Related
-
2013
- 2013-05-22 US US13/900,380 patent/US8703930B2/en not_active Expired - Fee Related
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