JP2011136997A5 - - Google Patents

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Publication number
JP2011136997A5
JP2011136997A5 JP2011000275A JP2011000275A JP2011136997A5 JP 2011136997 A5 JP2011136997 A5 JP 2011136997A5 JP 2011000275 A JP2011000275 A JP 2011000275A JP 2011000275 A JP2011000275 A JP 2011000275A JP 2011136997 A5 JP2011136997 A5 JP 2011136997A5
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JP
Japan
Prior art keywords
nucleic acid
protein
nucleotide sequence
mammal
immune response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011000275A
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English (en)
Japanese (ja)
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JP2011136997A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2011136997A publication Critical patent/JP2011136997A/ja
Publication of JP2011136997A5 publication Critical patent/JP2011136997A5/ja
Withdrawn legal-status Critical Current

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JP2011000275A 2003-09-17 2011-01-04 コンセンサス／先祖免疫原 Withdrawn JP2011136997A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50346003P 2003-09-17 2003-09-17
US60/503,460 2003-09-17
US60472204P 2004-08-27 2004-08-27
US60/604,722 2004-08-27

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2006527030A Division JP4773352B2 (ja) 2003-09-17 2004-09-17 コンセンサス／先祖免疫原

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013253689A Division JP6165612B2 (ja) 2003-09-17 2013-12-06 コンセンサス／先祖免疫原

Publications (2)

Publication Number Publication Date
JP2011136997A JP2011136997A (ja) 2011-07-14
JP2011136997A5 true JP2011136997A5 (https=) 2011-08-25

Family

ID=34381074

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2006527030A Expired - Fee Related JP4773352B2 (ja) 2003-09-17 2004-09-17 コンセンサス／先祖免疫原
JP2011000275A Withdrawn JP2011136997A (ja) 2003-09-17 2011-01-04 コンセンサス／先祖免疫原
JP2013253689A Expired - Fee Related JP6165612B2 (ja) 2003-09-17 2013-12-06 コンセンサス／先祖免疫原

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2006527030A Expired - Fee Related JP4773352B2 (ja) 2003-09-17 2004-09-17 コンセンサス／先祖免疫原

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013253689A Expired - Fee Related JP6165612B2 (ja) 2003-09-17 2013-12-06 コンセンサス／先祖免疫原

Country Status (10)

Country Link
US (3) US8071107B2 (https=)
EP (2) EP1667714B1 (https=)
JP (3) JP4773352B2 (https=)
KR (2) KR20070028291A (https=)
CN (2) CN102010463A (https=)
AU (1) AU2004274937B9 (https=)
BR (1) BRPI0414443A (https=)
CA (2) CA2539325C (https=)
IL (3) IL174380A0 (https=)
WO (1) WO2005028625A2 (https=)

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EP1307130A4 (en) 2000-02-04 2005-01-12 Beth Israel Hospital VACCINE AGAINST THE VIRUS OF HUMAN IMMUNODEFICIENCY
EP1331942A4 (en) 2000-09-22 2005-03-16 Univ Duke Immunogenic with ligand-bound HIV envelope protein
US7033593B2 (en) 2000-09-22 2006-04-25 Duke University Immunogen comprising an HIV envelope protein, a ligand and H2 peptide
CA2539325C (en) 2003-09-17 2016-03-22 Duke University Consensus/ancestral immunogens
US8048431B2 (en) * 2003-09-17 2011-11-01 Duke University Modified HIV-1 clade C envelope glycoprotein immunogens comprising deletions in the gp120/gp41 cleavage site and gp41 fusion domain
EP2309269B1 (en) 2004-09-08 2016-10-26 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Compositions and methods for the detection of HIV-1/HIV-2 infection.
CN101969996A (zh) * 2005-08-23 2011-02-09 加利福尼亚大学董事会 多价疫苗
US7951377B2 (en) * 2005-08-23 2011-05-31 Los Alamos National Security, Llc Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens
SG170092A1 (en) * 2006-03-10 2011-04-29 Peptcell Ltd Peptides of regulatory or accessory proteins of hiv, compositions and the utilization thereof
EP2001459B1 (en) * 2006-03-29 2012-07-11 Dana-Farber Cancer Institute, Inc. Methods and compositions for inducing an immune response to hiv and models for testing
CA2654324A1 (en) * 2006-06-02 2007-12-13 International Aids Vaccine Initiative Hiv-1 clade a consensus sequences, antigens, and transgenes
AU2007278831B2 (en) * 2006-07-28 2013-03-21 The Trustees Of The University Of Pennsylvania Improved vaccines and methods for using the same
AU2015234338C1 (en) * 2006-07-28 2017-07-20 The Trustees Of The University Of Pennsylvania Improved vaccines and methods for using the same
JP2010530356A (ja) * 2007-03-27 2010-09-09 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 急性伝染ｈｉｖエンベロープ・サイン
WO2010059732A1 (en) 2008-11-18 2010-05-27 Beth Israel Deaconess Medical Center Antiviral vaccines with improved cellular immunogenicity
WO2011106100A2 (en) 2010-02-25 2011-09-01 Duke University Method of inducing the production of protective anti-hiv-1 antibodies
AU2011221549A1 (en) * 2010-03-03 2012-11-01 Duke University Molecular clone of HIV-1
US20130273103A1 (en) * 2010-09-28 2013-10-17 Los Alamos National Security, Llc Polyvalent immunogen
EP2492279A1 (en) * 2011-02-25 2012-08-29 Laboratorios Del. Dr. Esteve, S.A. Rapid immunogen selection method using lentiviral display
EP2739300B1 (en) 2011-07-05 2019-06-19 Duke University N-terminal deleted gp120 immunogens
CA2850745C (en) * 2011-10-03 2022-12-13 Duke University Vaccine
EP2620446A1 (en) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
WO2013131099A1 (en) 2012-03-02 2013-09-06 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of altering the immundominance hierarchy of hiv gag by dna vaccine expressing conserved regions
KR20150036593A (ko) * 2012-07-24 2015-04-07 사노피 파스퇴르 뎅기열 바이러스 감염 예방용 백신 조성물
KR101826536B1 (ko) 2012-08-07 2018-02-07 현대자동차 주식회사 차량의 아이들 스톱 제어 방법 및 장치
WO2014151687A2 (en) 2013-03-15 2014-09-25 University Of Massachusetts Compositions and methods to treat aids
US9920305B2 (en) * 2013-10-16 2018-03-20 New England Biolabs, Inc. Reverse transcriptase with enhanced properties
MA40783A (fr) * 2014-10-03 2017-08-08 Los Alamos Nat Security Llc Vaccins contre le vih comprenant un ou plusieurs antigènes episensus de population
WO2017007646A1 (en) * 2015-07-07 2017-01-12 International Aids Vaccine Initiative Hiv-1 clade c envelope glycoproteins
US11318197B2 (en) 2016-03-03 2022-05-03 Duke University Compositions and methods for inducing HIV-1 antibodies
US11246920B2 (en) 2016-03-03 2022-02-15 Duke University Compositions and methods for inducing HIV-1 antibodies
AR109528A1 (es) * 2016-09-15 2018-12-19 Janssen Vaccines & Prevention Bv Mutaciones estabilizantes de trímeros de proteínas de la envoltura del vih
US10828363B1 (en) * 2016-09-16 2020-11-10 The Trustees Of The University Of Pennsylvania Extreme polyvalency induces potent cross-clade cellular and humoral responses in rabbits and non-human primates
EP3519428A4 (en) 2016-10-03 2020-07-08 Duke University METHODS OF IDENTIFYING IMMUNOGENS BY TARGETING IMPROBABLE MUTATIONS
US11230572B2 (en) 2016-10-17 2022-01-25 Beth Israel Deaconess Medical Center, Inc. Signature-based human immunodeficiency virus (HIV) envelope (Env) trimer vaccines and methods of using the same
US12138304B2 (en) 2018-10-01 2024-11-12 Duke University HIV-1 envelope stabilizing mutations
GB201816873D0 (en) * 2018-10-17 2018-11-28 Imperial Innovations Ltd Fusion protein
CN114761041A (zh) 2019-07-16 2022-07-15 吉利德科学公司 Hiv疫苗及其制备和使用方法
CA3161633A1 (en) 2019-11-14 2021-05-20 Aelix Therapeutics, S.L. Dosage regimens for vaccines
EP4277652A1 (en) 2021-01-14 2023-11-22 Gilead Sciences, Inc. Hiv vaccines and methods of using
US20250213675A1 (en) * 2022-03-31 2025-07-03 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Immunogens and vaccine compositions against hiv
WO2025072797A2 (en) * 2023-09-27 2025-04-03 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Immunogens and vaccine compositions against hiv

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US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US20030096778A1 (en) * 2002-06-13 2003-05-22 Shiver John W Polynucleotide vaccines expressing codon optimized hiv-1 nef and modified hiv-1 nef
US7655774B2 (en) 2000-02-18 2010-02-02 University Of Washington Ancestral and COT viral sequences, proteins and immunogenic compositions
JP2003523188A (ja) 2000-02-18 2003-08-05 ユニバーシティ・オブ・ワシントン Ａｉｄｓ先祖ウイルスおよびワクチン
US6733993B2 (en) * 2000-09-15 2004-05-11 Merck & Co., Inc. Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-gag, pol, nef and modifications
EP1331942A4 (en) 2000-09-22 2005-03-16 Univ Duke Immunogenic with ligand-bound HIV envelope protein
US7172761B2 (en) 2001-11-07 2007-02-06 Duke University Polyvalent immunogen
CA2539325C (en) 2003-09-17 2016-03-22 Duke University Consensus/ancestral immunogens
US8048431B2 (en) 2003-09-17 2011-11-01 Duke University Modified HIV-1 clade C envelope glycoprotein immunogens comprising deletions in the gp120/gp41 cleavage site and gp41 fusion domain
HRP20040589B1 (en) 2004-06-28 2011-07-31 Biljan Marijan The stand for garment hangers with a built-in counter

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