JP2011530309A5 - - Google Patents
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- Publication number
- JP2011530309A5 JP2011530309A5 JP2011523001A JP2011523001A JP2011530309A5 JP 2011530309 A5 JP2011530309 A5 JP 2011530309A5 JP 2011523001 A JP2011523001 A JP 2011523001A JP 2011523001 A JP2011523001 A JP 2011523001A JP 2011530309 A5 JP2011530309 A5 JP 2011530309A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- mammal
- polypeptide
- protein
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 4
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 2
- 230000006698 induction Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/192,015 US7951377B2 (en) | 2005-08-23 | 2008-08-14 | Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens |
| US12/192,015 | 2008-08-14 | ||
| PCT/US2009/004664 WO2010019262A2 (en) | 2008-08-14 | 2009-08-14 | Polyvalent vaccine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014120307A Division JP2014207910A (ja) | 2008-08-14 | 2014-06-11 | 多価ワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011530309A JP2011530309A (ja) | 2011-12-22 |
| JP2011530309A5 true JP2011530309A5 (https=) | 2012-10-04 |
Family
ID=41669535
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523001A Pending JP2011530309A (ja) | 2008-08-14 | 2009-08-14 | 多価ワクチン |
| JP2014120307A Pending JP2014207910A (ja) | 2008-08-14 | 2014-06-11 | 多価ワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014120307A Pending JP2014207910A (ja) | 2008-08-14 | 2014-06-11 | 多価ワクチン |
Country Status (9)
| Country | Link |
|---|---|
| US (6) | US7951377B2 (https=) |
| EP (2) | EP3178842B1 (https=) |
| JP (2) | JP2011530309A (https=) |
| CN (1) | CN102177175A (https=) |
| AU (1) | AU2009282442B2 (https=) |
| BR (1) | BRPI0917205A2 (https=) |
| CA (1) | CA2733898C (https=) |
| IL (1) | IL211184B (https=) |
| WO (1) | WO2010019262A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101969996A (zh) * | 2005-08-23 | 2011-02-09 | 加利福尼亚大学董事会 | 多价疫苗 |
| US7951377B2 (en) | 2005-08-23 | 2011-05-31 | Los Alamos National Security, Llc | Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens |
| WO2010059732A1 (en) | 2008-11-18 | 2010-05-27 | Beth Israel Deaconess Medical Center | Antiviral vaccines with improved cellular immunogenicity |
| EP2739300B1 (en) | 2011-07-05 | 2019-06-19 | Duke University | N-terminal deleted gp120 immunogens |
| CA2850745C (en) | 2011-10-03 | 2022-12-13 | Duke University | Vaccine |
| ES2728727T3 (es) | 2012-12-13 | 2019-10-28 | Baylor Res Institute At Dallas | Triheptanoína para el tratamiento de la deficiencia del transportador de glucosa 1 |
| ES2957209T3 (es) * | 2013-09-30 | 2024-01-15 | Triad Nat Security Llc | Polipéptidos inmunogénicos mosaicos del VIH de región conservada |
| US9920305B2 (en) | 2013-10-16 | 2018-03-20 | New England Biolabs, Inc. | Reverse transcriptase with enhanced properties |
| US10149902B2 (en) | 2014-03-19 | 2018-12-11 | Duke University | Swarm immunization with envelopes from CH505 |
| EP3122881A4 (en) * | 2014-03-25 | 2017-11-15 | Duke University | Mosaic hiv-1 sequences and uses thereof |
| US10322141B2 (en) | 2014-03-31 | 2019-06-18 | Duke University | Compositions comprising CH848 envelopes and uses thereof |
| CA2962938A1 (en) | 2014-09-28 | 2016-03-31 | Duke University | Compositions comprising ch505 envelopes, and trimers |
| CA3016327A1 (en) | 2016-03-01 | 2017-09-08 | Duke University | Compositions comprising hiv envelopes to induce ch235 lineage antibodies |
| US11318197B2 (en) | 2016-03-03 | 2022-05-03 | Duke University | Compositions and methods for inducing HIV-1 antibodies |
| US11246920B2 (en) | 2016-03-03 | 2022-02-15 | Duke University | Compositions and methods for inducing HIV-1 antibodies |
| EP3519428A4 (en) | 2016-10-03 | 2020-07-08 | Duke University | METHODS OF IDENTIFYING IMMUNOGENS BY TARGETING IMPROBABLE MUTATIONS |
| US11230572B2 (en) | 2016-10-17 | 2022-01-25 | Beth Israel Deaconess Medical Center, Inc. | Signature-based human immunodeficiency virus (HIV) envelope (Env) trimer vaccines and methods of using the same |
| WO2018218225A1 (en) | 2017-05-25 | 2018-11-29 | Duke University | Compositions comprising modified hiv envelopes |
| US12138304B2 (en) | 2018-10-01 | 2024-11-12 | Duke University | HIV-1 envelope stabilizing mutations |
| CN114761041A (zh) | 2019-07-16 | 2022-07-15 | 吉利德科学公司 | Hiv疫苗及其制备和使用方法 |
| US12559527B2 (en) | 2019-10-23 | 2026-02-24 | Duke University | Compositions comprising V2 opt HIV envelopes |
| EP4277652A1 (en) | 2021-01-14 | 2023-11-22 | Gilead Sciences, Inc. | Hiv vaccines and methods of using |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US6139843A (en) | 1991-04-02 | 2000-10-31 | Albert Einstein College Of Medicine Of Yeshiva University | Peptide compositions for the treatment of HIV |
| US6541011B2 (en) | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| US6503753B1 (en) | 1998-02-13 | 2003-01-07 | Adan Rios | Method for the development of an HIV vaccine |
| US20030180314A1 (en) | 1998-07-10 | 2003-09-25 | Degroot Anne | Immunogenic, cross-clade, HIV peptides |
| US7935805B1 (en) * | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
| US6710173B1 (en) * | 1999-06-25 | 2004-03-23 | Progenics Pharmaceuticals, Inc. | Stabilized viral envelope proteins and uses thereof |
| US20040115621A1 (en) * | 2000-02-18 | 2004-06-17 | Allen Rodrigo | Ancestral viruses and vaccines |
| US7655774B2 (en) * | 2000-02-18 | 2010-02-02 | University Of Washington | Ancestral and COT viral sequences, proteins and immunogenic compositions |
| US6733993B2 (en) | 2000-09-15 | 2004-05-11 | Merck & Co., Inc. | Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-gag, pol, nef and modifications |
| US7195768B2 (en) | 2001-11-07 | 2007-03-27 | Duke University | Polyvalent immunogen |
| US7153509B2 (en) | 2001-11-07 | 2006-12-26 | Duke University | Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope |
| US20070054262A1 (en) * | 2003-03-28 | 2007-03-08 | Baker Denise M | Methods of identifying optimal variants of peptide epitopes |
| CA2519025A1 (en) | 2003-03-28 | 2004-10-07 | The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services, Centers For Disea | Immunogenic hiv-1 multi-clade, multivalent constructs and methods of their use |
| ES2388527T3 (es) | 2003-09-15 | 2012-10-16 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Vacunas de VIH basadas en Env de múltiples clados de VIH |
| CA2539325C (en) | 2003-09-17 | 2016-03-22 | Duke University | Consensus/ancestral immunogens |
| WO2005035555A1 (en) * | 2003-10-10 | 2005-04-21 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hiv/siv env chimeras that promote trimerization and maintain targets of neutralizing antibodies |
| US7951377B2 (en) | 2005-08-23 | 2011-05-31 | Los Alamos National Security, Llc | Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens |
| CN101969996A (zh) | 2005-08-23 | 2011-02-09 | 加利福尼亚大学董事会 | 多价疫苗 |
| AU2006304725B2 (en) | 2005-10-17 | 2012-03-15 | Novartis Ag | Multiclade HIV vaccines |
| US20130273103A1 (en) | 2010-09-28 | 2013-10-17 | Los Alamos National Security, Llc | Polyvalent immunogen |
-
2008
- 2008-08-14 US US12/192,015 patent/US7951377B2/en not_active Expired - Fee Related
-
2009
- 2009-08-14 JP JP2011523001A patent/JP2011530309A/ja active Pending
- 2009-08-14 CN CN2009801404211A patent/CN102177175A/zh active Pending
- 2009-08-14 WO PCT/US2009/004664 patent/WO2010019262A2/en not_active Ceased
- 2009-08-14 AU AU2009282442A patent/AU2009282442B2/en not_active Ceased
- 2009-08-14 EP EP16184203.4A patent/EP3178842B1/en not_active Not-in-force
- 2009-08-14 CA CA2733898A patent/CA2733898C/en not_active Expired - Fee Related
- 2009-08-14 EP EP09806982A patent/EP2318430A4/en not_active Withdrawn
- 2009-08-14 BR BRPI0917205A patent/BRPI0917205A2/pt not_active IP Right Cessation
- 2009-08-14 US US12/737,761 patent/US9044445B2/en not_active Expired - Fee Related
-
2011
- 2011-02-10 IL IL211184A patent/IL211184B/en active IP Right Grant
- 2011-04-26 US US13/094,734 patent/US9011873B2/en not_active Expired - Fee Related
-
2014
- 2014-06-11 JP JP2014120307A patent/JP2014207910A/ja active Pending
-
2015
- 2015-04-17 US US14/689,995 patent/US9821053B2/en not_active Expired - Fee Related
- 2015-05-29 US US14/726,373 patent/US9844590B2/en not_active Expired - Fee Related
-
2017
- 2017-12-15 US US15/843,233 patent/US20180185471A1/en not_active Abandoned
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