JP2010540446A5 - - Google Patents
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- JP2010540446A5 JP2010540446A5 JP2010525937A JP2010525937A JP2010540446A5 JP 2010540446 A5 JP2010540446 A5 JP 2010540446A5 JP 2010525937 A JP2010525937 A JP 2010525937A JP 2010525937 A JP2010525937 A JP 2010525937A JP 2010540446 A5 JP2010540446 A5 JP 2010540446A5
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- JP
- Japan
- Prior art keywords
- composition
- decrease
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- caused
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000203 mixture Substances 0.000 claims 18
- 230000035945 sensitivity Effects 0.000 claims 10
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 7
- 108010036949 Cyclosporine Proteins 0.000 claims 7
- 229960001265 ciclosporin Drugs 0.000 claims 6
- 229930105110 Cyclosporin A Natural products 0.000 claims 5
- 208000036142 Viral infection Diseases 0.000 claims 5
- 230000009385 viral infection Effects 0.000 claims 5
- 238000001356 surgical procedure Methods 0.000 claims 3
- 108010013381 Porins Proteins 0.000 claims 2
- 229930182912 cyclosporin Natural products 0.000 claims 2
- 102000007739 porin activity proteins Human genes 0.000 claims 2
- 206010061788 Corneal infection Diseases 0.000 claims 1
- 241000700588 Human alphaherpesvirus 1 Species 0.000 claims 1
- 241000701074 Human alphaherpesvirus 2 Species 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 210000004087 cornea Anatomy 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/858,200 US20080146497A1 (en) | 2006-07-25 | 2007-09-20 | Cyclosporin Compositions |
| PCT/US2008/076756 WO2009099467A2 (en) | 2007-09-20 | 2008-09-18 | Cyclosporin compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010540446A JP2010540446A (ja) | 2010-12-24 |
| JP2010540446A5 true JP2010540446A5 (enExample) | 2011-11-10 |
Family
ID=39528114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010525937A Pending JP2010540446A (ja) | 2007-09-20 | 2008-09-18 | シクロスポリン組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080146497A1 (enExample) |
| EP (1) | EP2190407B1 (enExample) |
| JP (1) | JP2010540446A (enExample) |
| KR (1) | KR20100091946A (enExample) |
| CN (1) | CN101835463A (enExample) |
| AU (1) | AU2008349774A1 (enExample) |
| BR (1) | BRPI0816995A2 (enExample) |
| CA (1) | CA2700182A1 (enExample) |
| IL (1) | IL204614A0 (enExample) |
| MX (1) | MX2010003045A (enExample) |
| RU (1) | RU2010112472A (enExample) |
| WO (1) | WO2009099467A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
| MX2010003364A (es) | 2007-10-08 | 2010-07-06 | Lux Biosciences Inc | Composiciones oftalmicas que comprenden inhibidores de calcineurina o inhibidores de mtor. |
| WO2010127301A1 (en) * | 2009-05-01 | 2010-11-04 | Allergan, Inc. | Method of treating allergic conjunctivitis with cyclosporin compositions |
| US9017725B2 (en) * | 2009-06-09 | 2015-04-28 | Aurinia Pharmaceuticals Inc. | Topical drug delivery systems for ophthalmic use |
| RU2014129268A (ru) * | 2011-12-16 | 2016-02-10 | Аллерган, Инк. | Офтальмологические составы, которые содержат привитые сополимеры поливинилкапролактам-поливинилацетат-полиэтиленгликоля |
| FR2988297B1 (fr) * | 2012-03-22 | 2014-03-28 | Thea Lab | Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur |
| AU2013267435B2 (en) | 2012-06-01 | 2017-11-09 | Allergan, Inc. | Cyclosporin A analogs |
| EP3169308B1 (en) * | 2014-07-18 | 2021-01-27 | Allergan, Inc. | Suspension compositions of cyclosporin a for subconjunctival and periocular injection |
| KR101587412B1 (ko) * | 2014-10-17 | 2016-01-21 | 주식회사 휴온스 | 사이클로스포린 및 트레할로스를 포함하는 안과용 조성물 |
| WO2016112321A1 (en) | 2015-01-08 | 2016-07-14 | Allergan, Inc. | Cyclosporin derivatives wherein the mebmt sidechain has been cyclized |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| RU2762767C1 (ru) * | 2020-09-15 | 2021-12-22 | Федеральное государственное автономное учреждение "Национальный медицинский исследовательский центр "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Министерства здравоохранения Российской Федерации | Способ определения тактильной чувствительности роговицы |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2577049B2 (ja) * | 1987-06-04 | 1997-01-29 | 三共株式会社 | シクロスポリン製剤 |
| ATE109970T1 (de) * | 1987-09-03 | 1994-09-15 | Univ Georgia Res Found | Cyclosporin-augenmittel. |
| SG45449A1 (en) * | 1992-05-13 | 1998-01-16 | Sandoz Ltd | Ophthalmic compositions |
| EP1301210A2 (en) * | 2000-07-14 | 2003-04-16 | Allergan, Inc. | Compositions containing therapeutically active components having enhanced solubility |
| PL1904056T3 (pl) * | 2005-07-18 | 2009-09-30 | Minu Llc | Zastosowanie makrolidu do przywracania czucia rogówkowego |
| US7501393B2 (en) * | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| TWI435729B (zh) * | 2005-11-09 | 2014-05-01 | Combinatorx Inc | 治療病症之方法，組合物及套組 |
-
2007
- 2007-09-20 US US11/858,200 patent/US20080146497A1/en not_active Abandoned
-
2008
- 2008-09-18 CA CA2700182A patent/CA2700182A1/en not_active Abandoned
- 2008-09-18 WO PCT/US2008/076756 patent/WO2009099467A2/en not_active Ceased
- 2008-09-18 JP JP2010525937A patent/JP2010540446A/ja active Pending
- 2008-09-18 MX MX2010003045A patent/MX2010003045A/es not_active Application Discontinuation
- 2008-09-18 RU RU2010112472/15A patent/RU2010112472A/ru not_active Application Discontinuation
- 2008-09-18 EP EP08872212.9A patent/EP2190407B1/en not_active Not-in-force
- 2008-09-18 CN CN200880113223A patent/CN101835463A/zh active Pending
- 2008-09-18 KR KR1020107008509A patent/KR20100091946A/ko not_active Withdrawn
- 2008-09-18 BR BRPI0816995 patent/BRPI0816995A2/pt not_active IP Right Cessation
- 2008-09-18 AU AU2008349774A patent/AU2008349774A1/en not_active Abandoned
-
2010
- 2010-03-18 IL IL204614A patent/IL204614A0/en unknown
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