WO2008136034A3 - Ophthalmic compositions for the treatment of ocular hypertension and glaucoma - Google Patents

Ophthalmic compositions for the treatment of ocular hypertension and glaucoma Download PDF

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Publication number
WO2008136034A3
WO2008136034A3 PCT/IT2008/000299 IT2008000299W WO2008136034A3 WO 2008136034 A3 WO2008136034 A3 WO 2008136034A3 IT 2008000299 W IT2008000299 W IT 2008000299W WO 2008136034 A3 WO2008136034 A3 WO 2008136034A3
Authority
WO
WIPO (PCT)
Prior art keywords
glaucoma
treatment
ocular hypertension
ophthalmic compositions
relates
Prior art date
Application number
PCT/IT2008/000299
Other languages
French (fr)
Other versions
WO2008136034A2 (en
Inventor
Daniele Sher
Grasso Letizia Gaetana Lo
Francesco Giuliano
Original Assignee
Sifi Spa
Daniele Sher
Grasso Letizia Gaetana Lo
Francesco Giuliano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sifi Spa, Daniele Sher, Grasso Letizia Gaetana Lo, Francesco Giuliano filed Critical Sifi Spa
Publication of WO2008136034A2 publication Critical patent/WO2008136034A2/en
Publication of WO2008136034A3 publication Critical patent/WO2008136034A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Abstract

The present invention relates to the use of ophthalmic pharmaceutical compositions for the treatment of glaucoma and ocular hypertension. Particularly, the invention relates to ophthalmic formulations comprising a new active ingredient, optionally in combination with other active ingredients typically used in the treatment of ocular hypertension or glaucoma.
PCT/IT2008/000299 2007-05-04 2008-05-02 Ophthalmic compositions for the treatment of ocular hypertension and glaucoma WO2008136034A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000890A ITMI20070890A1 (en) 2007-05-04 2007-05-04 OPHTHALMIC COMPOSITIONS FOR THE TREATMENT OF OCULAR HYPERTENSION AND GLAUCOMA
ITMI2007A000890 2007-05-04

Publications (2)

Publication Number Publication Date
WO2008136034A2 WO2008136034A2 (en) 2008-11-13
WO2008136034A3 true WO2008136034A3 (en) 2008-12-24

Family

ID=39791437

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2008/000299 WO2008136034A2 (en) 2007-05-04 2008-05-02 Ophthalmic compositions for the treatment of ocular hypertension and glaucoma

Country Status (2)

Country Link
IT (1) ITMI20070890A1 (en)
WO (1) WO2008136034A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2547323T3 (en) 2010-03-17 2016-05-02 Novaliq Gmbh PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INCREASED INTRAOCULAR PRESSURE
EP2444063A1 (en) 2010-10-20 2012-04-25 Novaliq GmbH Liquid pharmaceutical compositions for the delivery of active ingredients
JP7219223B2 (en) 2017-03-10 2023-02-07 ファイザー・インク Novel imidazo[4,5-c]quinoline derivatives as LRRK2 inhibitors
AU2018279074B2 (en) * 2017-06-08 2023-12-14 Eye Therapies, Llc Low-dose brimonidine combinations and uses thereof
BR112020006072A2 (en) 2017-09-27 2020-10-06 Novaliq Gmbh ophthalmic compositions comprising latanoprost for use in the treatment of eye diseases
WO2019166631A1 (en) 2018-03-02 2019-09-06 Novaliq Gmbh Pharmaceutical compositions comprising nebivolol
WO2020250252A1 (en) 2019-06-11 2020-12-17 Sifi S.P.A. Microemulsion compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050272810A1 (en) * 2004-06-04 2005-12-08 Eric Davis Compositions comprising nebivolol
WO2006113485A2 (en) * 2005-04-15 2006-10-26 Board Of Trustees Of Michigan State University Aminergic pharmaceutical compositions and methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050272810A1 (en) * 2004-06-04 2005-12-08 Eric Davis Compositions comprising nebivolol
WO2006113485A2 (en) * 2005-04-15 2006-10-26 Board Of Trustees Of Michigan State University Aminergic pharmaceutical compositions and methods

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHAN T Y K ET AL: "The application of nebivolol in essential hypertension: a double-blind, randomized, placebo-controlled study", INTERNATIONAL JOURNAL OF CARDIOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 35, no. 3, 1 June 1992 (1992-06-01), pages 387 - 395, XP023160607, ISSN: 0167-5273, [retrieved on 19920601] *
GALAMBOS: "Systemic Betablocker Treatment with Nebivolol enhances Ocular Hemodynamics in Glaucoma Patients with Arterial Hypertension", INVEST OPHTHALMOL VIS SCI, vol. 47, 2006, E-Abstract, pages 485, XP002499359 *
HOYNG P F J ET AL: "PHARMACOLOGICAL THERAPY FOR GLAUCOMA", DRUGS, ADIS INTERNATIONAL LTD, vol. 59, no. 3, 1 January 2000 (2000-01-01), pages 411 - 434, XP009014419, ISSN: 0012-6667 *

Also Published As

Publication number Publication date
WO2008136034A2 (en) 2008-11-13
ITMI20070890A1 (en) 2008-11-05

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