|
US9089610B2
(en)
|
2008-08-19 |
2015-07-28 |
Nektar Therapeutics |
Complexes of small-interfering nucleic acids
|
|
AR081361A1
(es)
|
2010-04-30 |
2012-08-29 |
Molecular Partners Ag |
Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a
|
|
DK2643349T3
(da)
|
2010-11-26 |
2019-11-25 |
Molecular Partners Ag |
Designede repeat-proteiner, der binder til serumalbumin
|
|
RS58620B1
(sr)
|
2011-02-15 |
2019-05-31 |
Immunogen Inc |
Metodi pripremanja konjugata
|
|
EA029797B1
(ru)
|
2011-06-21 |
2018-05-31 |
Иммуноджен, Инк. |
Новые производные майтанзиноида с пептидным линкером и их конъюгаты
|
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
|
JP6423804B2
(ja)
|
2013-02-28 |
2018-11-14 |
イミュノジェン・インコーポレーテッド |
細胞結合剤及び細胞毒性剤を含む複合体
|
|
WO2014134483A2
(en)
|
2013-02-28 |
2014-09-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
US11453708B2
(en)
|
2013-05-31 |
2022-09-27 |
Molecular Partners Ag |
Designed ankyrin repeat proteins binding to hepatocyte growth factor
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
MX389160B
(es)
|
2013-10-31 |
2025-03-20 |
Hutchinson Fred Cancer Res |
Células no t efectoras y madre/progenitoras hematopoyéticas modificadas y usos de estas.
|
|
CA2933707A1
(en)
|
2013-12-20 |
2015-06-25 |
Fred Hutchinson Cancer Research Center |
Tagged chimeric effector molecules and receptors thereof
|
|
CN106605228B
(zh)
|
2014-07-07 |
2019-08-16 |
耶达研究及发展有限公司 |
计算蛋白质设计的方法
|
|
KR20240023671A
(ko)
|
2014-09-03 |
2024-02-22 |
이뮤노젠 아이엔씨 |
세포독성 벤조다이아제핀 유도체
|
|
TW201613930A
(en)
|
2014-09-03 |
2016-04-16 |
Immunogen Inc |
Cytotoxic benzodiazepine derivatives
|
|
ES2979088T3
(es)
|
2015-03-05 |
2024-09-24 |
Fred Hutchinson Cancer Center |
Proteínas de fusión inmunomoduladoras y usos de las mismas
|
|
WO2016156596A1
(en)
|
2015-04-02 |
2016-10-06 |
Molecular Partners Ag |
Designed ankyrin repeat domains with binding specificity for serum albumin
|
|
EP3288570A4
(en)
|
2015-04-29 |
2018-11-21 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
EP3288569A4
(en)
|
2015-04-29 |
2018-12-19 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
WO2017106728A2
(en)
*
|
2015-12-16 |
2017-06-22 |
University Of Washington |
Repeat protein architectures
|
|
NZ748378A
(en)
|
2016-04-14 |
2025-08-29 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
MX377424B
(es)
|
2016-09-22 |
2025-03-10 |
Molecular Partners Ag |
Proteinas de union recombinantes y sus usos
|
|
IL268349B2
(en)
|
2017-02-17 |
2024-08-01 |
Hutchinson Fred Cancer Res |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
CN116785450A
(zh)
|
2017-02-28 |
2023-09-22 |
伊缪诺金公司 |
具有自分解肽接头的类美登素衍生物和其缀合物
|
|
WO2018165046A1
(en)
|
2017-03-07 |
2018-09-13 |
Igc Bio, Inc. |
A computational pipeline for antibody modeling and design
|
|
JP2020511136A
(ja)
|
2017-03-17 |
2020-04-16 |
フレッド ハッチンソン キャンサー リサーチ センター |
免疫調節性融合タンパク質およびその使用
|
|
WO2018195243A1
(en)
|
2017-04-20 |
2018-10-25 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
|
EP3732178A1
(en)
|
2017-12-28 |
2020-11-04 |
ImmunoGen, Inc. |
Benzodiazepine derivatives
|
|
EP4268831A3
(en)
|
2018-09-12 |
2024-05-22 |
Fred Hutchinson Cancer Center |
Reducing cd33 expression to selectively protect therapeutic cells
|
|
AU2020240310A1
(en)
|
2019-03-21 |
2021-10-07 |
Immunogen, Inc. |
Methods of preparing cell-binding agent-drug conjugates
|
|
EP3947395A1
(en)
|
2019-03-29 |
2022-02-09 |
ImmunoGen, Inc. |
Cytotoxic bis-benzodiazepine derivatives and conjugates thereof with cell-binding agents for inhibiting abnormal cell growth or for treating proliferative diseases
|
|
EP3958977B1
(en)
|
2019-04-26 |
2023-09-13 |
ImmunoGen, Inc. |
Camptothecin derivatives
|
|
CA3139164A1
(en)
|
2019-06-04 |
2020-12-10 |
Molecular Partners Ag |
Recombinant fap binding proteins and their use
|
|
CN114206908B
(zh)
|
2019-06-04 |
2025-12-23 |
分子伴侣公司 |
具有改善的稳定性的经设计的锚蛋白重复结构域
|
|
EP3980452A1
(en)
|
2019-06-04 |
2022-04-13 |
Molecular Partners AG |
Recombinant 4-1bb binding proteins and their use
|
|
BR112021026832A2
(pt)
|
2019-07-02 |
2022-05-10 |
Hutchinson Fred Cancer Res |
Vetores ad35 recombinantes e aprimoramentos da terapia gênica relacionada
|
|
JP2023506763A
(ja)
|
2019-12-11 |
2023-02-20 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
組換えペプチド－ｍｈｃ複合体結合タンパク質並びにそれらの生成及び使用
|
|
WO2021116462A1
(en)
|
2019-12-11 |
2021-06-17 |
Molecular Partners Ag |
Designed ankyrin repeat domains with altered surface residues
|
|
US20230142283A1
(en)
*
|
2020-03-05 |
2023-05-11 |
University Of Washington |
Rigid helical junctions for modular repeat protein sculpting and methods of use
|
|
TW202208404A
(zh)
|
2020-05-06 |
2022-03-01 |
瑞士商分子組合公司 |
新穎錨蛋白重複結合蛋白質及其用途
|
|
CN115768786A
(zh)
|
2020-05-14 |
2023-03-07 |
分子合作伙伴股份公司 |
多特异性蛋白质
|
|
US20240279309A1
(en)
|
2020-05-14 |
2024-08-22 |
Molecular Partners Ag |
Recombinant cd40 binding proteins and their use
|
|
EP4263608A1
(en)
|
2020-12-16 |
2023-10-25 |
Molecular Partners AG |
Recombinant cd3 binding proteins and their use
|
|
CA3202358A1
(en)
|
2020-12-16 |
2022-06-23 |
Andreas BOSSHART |
Novel slow-release prodrugs
|
|
JP2024509904A
(ja)
|
2021-03-09 |
2024-03-05 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
新規なＤＡＲＰｉｎに基づく多重特異性Ｔ細胞エンゲージャ
|
|
US20240150475A1
(en)
|
2021-03-09 |
2024-05-09 |
Molecular Partners Ag |
Novel darpin based cd123 engagers
|
|
WO2022190008A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Protease cleavable prodrugs
|
|
CA3211248A1
(en)
|
2021-03-09 |
2022-09-15 |
Nina RESCHKE |
Novel darpin based cd33 engagers
|
|
AU2022413461A1
(en)
|
2021-12-14 |
2024-06-06 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity and their use
|
|
EP4460511A1
(en)
*
|
2022-01-07 |
2024-11-13 |
Universität Zürich |
Stabilizing n-cap sequences for armadillo repeat proteins
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
CN119731200A
(zh)
|
2022-08-01 |
2025-03-28 |
分子合作伙伴股份公司 |
经电荷修饰设计的重复结构域及其用途
|
|
WO2024179981A1
(en)
|
2023-02-27 |
2024-09-06 |
Molecular Partners Ag |
Darpins for use in reducing renal accumulation of drugs
|
|
WO2024251628A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd16a binding proteins and their use
|
|
WO2024251695A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd47 binding proteins and their use
|
|
WO2024251742A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd2 binding proteins and their use
|
|
WO2025068607A1
(en)
*
|
2023-09-29 |
2025-04-03 |
Universität Zürich |
Modular armadillo repeat proteins
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2025146487A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Multispecific binding proteins
|
|
WO2025146490A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Recombinant cd117 binding proteins and their use
|
|
WO2025146491A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
|
|
WO2025163144A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Recombinant mesothelin binding proteins and their use
|
|
US20250332297A1
(en)
|
2024-01-31 |
2025-10-30 |
Molecular Partners Ag |
Dll3-specific binding constructs and their use in radiotherapy
|
|
WO2025181039A1
(en)
|
2024-03-01 |
2025-09-04 |
Molecular Partners Ag |
Therapeutic combinations comprising a multi-specific t cell engager
|
|
WO2025245169A1
(en)
|
2024-05-21 |
2025-11-27 |
Fred Hutchinson Cancer Center |
Immunotherapy cells equipped with a collagen-targeting payload
|