JP2010539180A5 - - Google Patents

Download PDF

Info

Publication number
JP2010539180A5
JP2010539180A5 JP2010524978A JP2010524978A JP2010539180A5 JP 2010539180 A5 JP2010539180 A5 JP 2010539180A5 JP 2010524978 A JP2010524978 A JP 2010524978A JP 2010524978 A JP2010524978 A JP 2010524978A JP 2010539180 A5 JP2010539180 A5 JP 2010539180A5
Authority
JP
Japan
Prior art keywords
pyrrolidin
ylethyl
oxo
tetrahydroisoquinolin
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010524978A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010539180A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/075981 external-priority patent/WO2009036144A1/en
Publication of JP2010539180A publication Critical patent/JP2010539180A/ja
Publication of JP2010539180A5 publication Critical patent/JP2010539180A5/ja
Withdrawn legal-status Critical Current

Links

JP2010524978A 2007-09-12 2008-09-11 ヒスタミン３拮抗薬としてのイソキノリニルおよびイソインドリニル誘導体 Withdrawn JP2010539180A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99363607P 2007-09-12 2007-09-12
PCT/US2008/075981 WO2009036144A1 (en) 2007-09-12 2008-09-11 Isoquinolinyl and isoindolinyl derivatives as histamine-3 antagonists

Publications (2)

Publication Number Publication Date
JP2010539180A JP2010539180A (ja) 2010-12-16
JP2010539180A5 true JP2010539180A5 (enExample) 2011-09-29

Family

ID=40261509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010524978A Withdrawn JP2010539180A (ja) 2007-09-12 2008-09-11 ヒスタミン３拮抗薬としてのイソキノリニルおよびイソインドリニル誘導体

Country Status (25)

Country Link
US (1) US20090069300A1 (enExample)
EP (1) EP2200989A1 (enExample)
JP (1) JP2010539180A (enExample)
KR (1) KR20100054856A (enExample)
CN (1) CN101848896A (enExample)
AP (1) AP2010005202A0 (enExample)
AR (1) AR068423A1 (enExample)
AU (1) AU2008298926A1 (enExample)
BR (1) BRPI0817061A2 (enExample)
CA (1) CA2699384A1 (enExample)
CL (1) CL2008002726A1 (enExample)
CO (1) CO6300955A2 (enExample)
CR (1) CR11303A (enExample)
DO (1) DOP2010000079A (enExample)
EA (1) EA201000316A1 (enExample)
EC (1) ECSP10010025A (enExample)
MA (1) MA31699B1 (enExample)
MX (1) MX2010002760A (enExample)
NI (1) NI201000036A (enExample)
PA (1) PA8795701A1 (enExample)
PE (1) PE20090651A1 (enExample)
TN (1) TN2010000105A1 (enExample)
TW (1) TW200927114A (enExample)
WO (1) WO2009036144A1 (enExample)
ZA (1) ZA201001751B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200823204A (en) * 2006-10-17 2008-06-01 Arena Pharm Inc Biphenyl sulfonyl and phenyl-heteroaryl sulfonyl modulators of the histamine H3-receptor useful for the treatment of disorders related thereto
GB0907284D0 (en) 2009-04-28 2009-06-10 Queen Mary & Westfield College Compounds for inducing cellular apoptosis
HUE034911T2 (hu) 2009-07-27 2018-03-28 Gilead Sciences Inc Fúzionált heterociklusos vegyületek mint ioncsatorna modulátorok
EP2588197B1 (en) 2010-07-02 2014-11-05 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
US20130203756A1 (en) * 2010-10-29 2013-08-08 Jamie L. Bunda Isoindoline pde10 inhibitors
WO2012154760A1 (en) * 2011-05-10 2012-11-15 Gilead Sciences, Inc. Fused heterocyclic compounds as sodium channel modulators
NO3175985T3 (enExample) 2011-07-01 2018-04-28
UY34171A (es) 2011-07-01 2013-01-31 Gilead Sciences Inc Compuestos heterocíclicos fusionados como moduladores del canal iónico
BR112014000267A2 (pt) 2011-07-04 2016-09-20 Bayer Ip Gmbh utilização de isoquinolinonas, isoquinolinedionas, isoquinolinetrionas e dihidroisoquinolinonas substituídas ou, em cada caso, sais das mesmas como agentes ativos contra o stress abiótico em plantas
WO2013076590A1 (en) 2011-11-23 2013-05-30 Oxygen Healthcare Research Pvt. Ltd Benzothiazine compounds as h3 receptor ligands
CN105254554B (zh) * 2014-07-14 2018-01-30 南开大学 一种制备异吲哚啉酮类化合物的方法
CA3174353A1 (en) * 2020-04-08 2021-10-14 Dominic Reynolds Compounds and methods for modulating splicing
CA3191279A1 (en) * 2020-08-28 2022-03-03 Yi Liu Heterocyclic compounds and uses thereof
US12496297B1 (en) * 2020-10-23 2025-12-16 Washington University Compositions of autophagy modulating agents and uses thereof
CN115819347B (zh) * 2022-11-14 2024-08-30 暨明医药科技（苏州）有限公司 一种1-烷基-3-溴吡唑的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933829A (en) * 1974-08-22 1976-01-20 John Wyeth & Brother Limited 4-Aminoquinoline derivatives
US4166853A (en) * 1978-05-05 1979-09-04 The Upjohn Company Antihypertensive 7-trifluoromethyl-4-aminoquinolones
US4159331A (en) * 1978-05-05 1979-06-26 The Upjohn Company Antihypertensive 4-aminoquinolines
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
ATE253359T1 (de) * 1997-05-01 2003-11-15 Lilly Co Eli Antithrombotische mittel
JP2004532834A (ja) 2001-03-23 2004-10-28 イーライ・リリー・アンド・カンパニー ヒスタミンｈ３受容体アンタゴニストである非イミダゾール系アリールアルキルアミン化合物、その製造および治療的使用
PT2208727E (pt) * 2002-09-19 2012-10-11 Lilly Co Eli Éteres diarílicos como antagonista do receptor opióide
KR101792651B1 (ko) * 2004-05-14 2017-11-20 밀레니엄 파머슈티컬스 인코퍼레이티드 아우로라 키나아제의 억제에 의해 유사분열 진행을 억제하기 위한 화합물 및 그 화합물을 포함하는 약학적 조성물
US20060014733A1 (en) * 2004-07-19 2006-01-19 Pfizer Inc Histamine-3 agonists and antagonists
US7381732B2 (en) * 2004-10-26 2008-06-03 Bristol-Myers Squibb Company Pyrazolobenzamides and derivatives as factor Xa inhibitors
EP1848696A1 (en) * 2005-01-21 2007-10-31 Schering Corporation Imidazole and benzimidazole derivates useful as histamine h3 antagonists
US20070032475A1 (en) * 2005-04-15 2007-02-08 Ye Xiaocong M Novel compounds useful for bradykinin B1 receptor antagonism

Similar Documents

Publication Publication Date Title
JP6298115B2 (ja) Ｌｒｒｋ２調節薬としてのピラゾールアミノピリミジン誘導体
US10519137B2 (en) Pyrazolyl quinoxaline kinase inhibitors
JP2022531801A5 (enExample)
RU2015122414A (ru) Соединения n-пирролидинилмочевины, n'-пиразолилмочевины, тиомочевины, гуанидина и цианогуанидина как ингибиторы киназы trka
RU2015132181A (ru) Фтор-[1,3]-оксазины в качестве ингибиторов васе1
JP2011518836A5 (enExample)
CA2567662A1 (en) Compounds and compositions as protein kinase inhibitors
JP2019525941A5 (enExample)
JP2019519484A5 (enExample)
JP2020505454A5 (enExample)
JP2013531074A5 (enExample)
RU2016133684A (ru) Бициклические азот-содержащие соединения как агонисты М1 мускариновых рецепторов
JP2010539180A (ja) ヒスタミン３拮抗薬としてのイソキノリニルおよびイソインドリニル誘導体
KR102082331B1 (ko) Cot 조정제로서의 6-아미노-퀴놀린-3-카르보니트릴
JP2013519733A5 (enExample)
JP2011503166A5 (enExample)
JP2014517833A5 (enExample)
RU2017124425A (ru) Производные 2,4-диоксо-хиназолин-6-сульфонамида в качестве ингибиторов parg
RU2018142987A (ru) Положительные аллостерические модуляторы мускаринового ацетилхолинового рецептора m4
JP2015514072A5 (enExample)
JP2013510876A5 (enExample)
JP2016532656A5 (enExample)
JP2013508403A (ja) オレキシン受容体調節因子としての二置換オクタヒドロピロロ［３，４−ｃ］ピロール
JP2014528446A5 (enExample)
JP2016512259A5 (enExample)