JP2010538094A - チロシンキナーゼ阻害剤としてのピラゾロピリジン類 - Google Patents
チロシンキナーゼ阻害剤としてのピラゾロピリジン類 Download PDFInfo
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- JP2010538094A JP2010538094A JP2010524200A JP2010524200A JP2010538094A JP 2010538094 A JP2010538094 A JP 2010538094A JP 2010524200 A JP2010524200 A JP 2010524200A JP 2010524200 A JP2010524200 A JP 2010524200A JP 2010538094 A JP2010538094 A JP 2010538094A
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- alkyl
- compound
- heteroaryl
- substituted
- aryl
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Oncology (AREA)
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- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
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- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
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- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97047207P | 2007-09-06 | 2007-09-06 | |
| PCT/US2008/075477 WO2009033084A1 (en) | 2007-09-06 | 2008-09-05 | Pyrazolo-pyridines as tyrosine kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010538094A true JP2010538094A (ja) | 2010-12-09 |
| JP2010538094A5 JP2010538094A5 (OSRAM) | 2012-09-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524200A Withdrawn JP2010538094A (ja) | 2007-09-06 | 2008-09-05 | チロシンキナーゼ阻害剤としてのピラゾロピリジン類 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110130406A1 (OSRAM) |
| EP (1) | EP2193130A1 (OSRAM) |
| JP (1) | JP2010538094A (OSRAM) |
| CN (1) | CN101918403A (OSRAM) |
| CA (1) | CA2698753A1 (OSRAM) |
| WO (1) | WO2009033084A1 (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016521757A (ja) * | 2013-06-19 | 2016-07-25 | 中国科学院上海薬物研究所 | 五員複素環縮合ピリジン系化合物、並びにその調製方法および用途 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101528702A (zh) * | 2006-06-08 | 2009-09-09 | 阿雷生物药品公司 | 喹啉化合物和使用方法 |
| CN102014913A (zh) * | 2008-03-06 | 2011-04-13 | 健泰科生物技术公司 | C-met和egfr拮抗剂的联合疗法 |
| US8293897B2 (en) | 2008-10-14 | 2012-10-23 | Ning Xi | Compounds comprising a spiro-ring and methods of use |
| AU2010229147B2 (en) | 2009-03-21 | 2012-07-05 | Sunshine Lake Pharma Co., Ltd. | Amino ester derivatives, salts thereof and methods of use |
| US20120058985A1 (en) | 2010-04-29 | 2012-03-08 | Deciphera Pharmaceuticals, Llc | Cyclopropyl dicarboxamides and analogs exhibiting anti-cancer and anti-proliferative activities |
| CA2800998A1 (en) | 2010-04-29 | 2011-11-10 | Deciphera Pharmaceuticals, Llc | Pyridone amides and analogs exhibiting anti-cancer and anti-proliferative activities |
| WO2012003338A1 (en) | 2010-07-01 | 2012-01-05 | Takeda Pharmaceutical Company Limited | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET |
| TW201247631A (en) | 2011-04-28 | 2012-12-01 | Du Pont | Herbicidal pyrazinones |
| EP3122900A1 (en) | 2014-03-24 | 2017-02-01 | F. Hoffmann-La Roche AG | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| WO2016004272A1 (en) | 2014-07-02 | 2016-01-07 | Pharmacyclics Llc | Inhibitors of bruton's tyrosine kinase |
| US10398774B2 (en) | 2014-12-09 | 2019-09-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Human monoclonal antibodies against AXL |
| WO2016135041A1 (en) | 2015-02-26 | 2016-09-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Fusion proteins and antibodies comprising thereof for promoting apoptosis |
| ES2904511T3 (es) | 2015-03-17 | 2022-04-05 | Nippon Chemiphar Co | Derivado de morfinano |
| ES2908801T3 (es) | 2016-06-07 | 2022-05-04 | Jacobio Pharmaceuticals Co Ltd | Nuevos derivados heterocíclicos útiles como inhibidores de SHP2 |
| WO2018049271A1 (en) * | 2016-09-09 | 2018-03-15 | Flx Bio, Inc. | Chemokine receptor modulators and uses thereof |
| US11633392B2 (en) | 2016-09-16 | 2023-04-25 | Nippon Chemiphar Co., Ltd. | Use of morphinan derivative for therapeutic treatment of opioid delta receptor agonist-related disease |
| DK3601239T3 (da) | 2017-03-23 | 2024-09-30 | Jacobio Pharmaceuticals Co Ltd | Novel heterocyclic derivatives useful as shp2 inhibitors |
| CN112839935A (zh) | 2018-09-26 | 2021-05-25 | 北京加科思新药研发有限公司 | 可用作shp2抑制剂的新型杂环衍生物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2572331A1 (en) * | 2004-07-02 | 2006-02-09 | Exelixis, Inc. | C-met modulators and method of use |
| US7547782B2 (en) * | 2005-09-30 | 2009-06-16 | Bristol-Myers Squibb Company | Met kinase inhibitors |
-
2008
- 2008-09-05 JP JP2010524200A patent/JP2010538094A/ja not_active Withdrawn
- 2008-09-05 WO PCT/US2008/075477 patent/WO2009033084A1/en not_active Ceased
- 2008-09-05 CN CN2008801150441A patent/CN101918403A/zh active Pending
- 2008-09-05 US US12/676,790 patent/US20110130406A1/en not_active Abandoned
- 2008-09-05 EP EP08799257A patent/EP2193130A1/en not_active Withdrawn
- 2008-09-05 CA CA2698753A patent/CA2698753A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016521757A (ja) * | 2013-06-19 | 2016-07-25 | 中国科学院上海薬物研究所 | 五員複素環縮合ピリジン系化合物、並びにその調製方法および用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2698753A1 (en) | 2009-03-12 |
| EP2193130A1 (en) | 2010-06-09 |
| US20110130406A1 (en) | 2011-06-02 |
| WO2009033084A1 (en) | 2009-03-12 |
| CN101918403A (zh) | 2010-12-15 |
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