|
US121022A
(en)
|
|
1871-11-14 |
|
Improvement in harness-fviountings |
|
US943525A
(en)
|
1908-01-04 |
1909-12-14 |
William Henry Drake |
Folding crate.
|
|
US5292668A
(en)
|
1981-12-21 |
1994-03-08 |
Boston Biomedical Research Institute, Inc. |
Bispecific antibody determinants
|
|
US4444878A
(en)
|
1981-12-21 |
1984-04-24 |
Boston Biomedical Research Institute, Inc. |
Bispecific antibody determinants
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
FR2604092B1
(fr)
|
1986-09-19 |
1990-04-13 |
Immunotech Sa |
Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
|
|
CA1335879C
(en)
|
1987-07-27 |
1995-06-13 |
Bruce Andrew Cornell |
Receptor membranes
|
|
US5766960A
(en)
|
1987-07-27 |
1998-06-16 |
Australian Membrane And Biotechnology Research Institute |
Receptor membranes
|
|
US4943525A
(en)
|
1987-11-02 |
1990-07-24 |
Bioventures, Inc. |
Simultaneous immunoassay for the determination of antigens and antibodies
|
|
US4892824A
(en)
|
1988-03-15 |
1990-01-09 |
Synbiotics Corporation |
Fast track method for producing monoclonal bi-specific immunoglobulins
|
|
US6010902A
(en)
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
|
US20030068322A1
(en)
|
1988-04-18 |
2003-04-10 |
Immunomedics, Inc. |
Methods of antibody-directed enzyme-prodrug therapy
|
|
US5851527A
(en)
|
1988-04-18 |
1998-12-22 |
Immunomedics, Inc. |
Method for antibody targeting of therapeutic agents
|
|
ES2052027T5
(es)
|
1988-11-11 |
2005-04-16 |
Medical Research Council |
Clonacion de secuencias de dominio variable de inmunoglobulina.
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US6020145A
(en)
|
1989-06-30 |
2000-02-01 |
Bristol-Myers Squibb Company |
Methods for determining the presence of carcinoma using the antigen binding region of monoclonal antibody BR96
|
|
IL94872A
(en)
|
1989-06-30 |
1995-03-30 |
Oncogen |
Monoclonal or chimeric antibodies reactive with human carcinomas, recombinant proteins comprising their antigen binding region, pharmaceutical compositions and kits comprising said antibodies and methods for imaging human carcinoma using same
|
|
US5980896A
(en)
|
1989-06-30 |
1999-11-09 |
Bristol-Myers Squibb Company |
Antibodies reactive with human carcinomas
|
|
US5332567A
(en)
|
1989-08-24 |
1994-07-26 |
Immunomedics |
Detection and treatment of infections with immunoconjugates
|
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
|
US5872222A
(en)
|
1991-04-19 |
1999-02-16 |
Tanox Biosystems, Inc. |
Conjugates of polymers and antibodies specific for T lymphocytes, and their use as adjuvants
|
|
US6197298B1
(en)
|
1991-04-19 |
2001-03-06 |
Tanox, Inc. |
Modified binding molecules specific for T lymphocytes and their use as in vivo immune modulators in animals
|
|
US6129916A
(en)
|
1991-04-19 |
2000-10-10 |
Tanox, Inc. |
Method of Increasing activation on proliferation of T cells using antibody-microbead conjugates
|
|
US6106835A
(en)
|
1991-04-19 |
2000-08-22 |
Tanox, Inc. |
Modified binding molecules specific for T or B lymphocytes and their use as in vivo immune modulators
|
|
CA2065658A1
(en)
|
1991-04-19 |
1992-10-20 |
Tse-Wen Chang |
Conjugates of liposomes or microbeads and antibodies specific for t lymphocytes and their use in vivo immune modulators
|
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
|
US6887471B1
(en)
|
1991-06-27 |
2005-05-03 |
Bristol-Myers Squibb Company |
Method to inhibit T cell interactions with soluble B7
|
|
EP0606217B2
(en)
|
1991-06-27 |
2008-12-03 |
Bristol-Myers Squibb Company |
Ctl4a receptor, fusion proteins containing it and uses thereof
|
|
US6090914A
(en)
|
1991-06-27 |
2000-07-18 |
Bristol-Myers Squibb Company |
CTLA4/CD28Ig hybrid fusion proteins and uses thereof
|
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
|
US5770197A
(en)
|
1991-06-27 |
1998-06-23 |
Bristol-Myers Squibb Company |
Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules
|
|
US5844095A
(en)
|
1991-06-27 |
1998-12-01 |
Bristol-Myers Squibb Company |
CTLA4 Ig fusion proteins
|
|
US5851795A
(en)
|
1991-06-27 |
1998-12-22 |
Bristol-Myers Squibb Company |
Soluble CTLA4 molecules and uses thereof
|
|
DE4134982A1
(de)
|
1991-10-23 |
1993-04-29 |
Kernforschungsz Karlsruhe |
Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression
|
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
DE4140142A1
(de)
|
1991-12-05 |
1993-06-09 |
Boehringer Mannheim Gmbh, 6800 Mannheim, De |
Multivalentes dextranreagenz zum einsatz in praezipitationstests
|
|
AU668374B2
(en)
|
1991-12-10 |
1996-05-02 |
Dana-Farber Cancer Institute |
Reactive neutralizing human anti-GP120 recombinant antibody, DNA coding the same and use thereof
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
WO1993016185A2
(en)
|
1992-02-06 |
1993-08-19 |
Creative Biomolecules, Inc. |
Biosynthetic binding protein for cancer marker
|
|
US6004555A
(en)
|
1992-03-05 |
1999-12-21 |
Board Of Regents, The University Of Texas System |
Methods for the specific coagulation of vasculature
|
|
US6093399A
(en)
|
1992-03-05 |
2000-07-25 |
Board Of Regents, The University Of Texas System |
Methods and compositions for the specific coagulation of vasculature
|
|
US5877289A
(en)
|
1992-03-05 |
1999-03-02 |
The Scripps Research Institute |
Tissue factor compositions and ligands for the specific coagulation of vasculature
|
|
US5776427A
(en)
|
1992-03-05 |
1998-07-07 |
Board Of Regents, The University Of Texas System |
Methods for targeting the vasculature of solid tumors
|
|
WO1993017715A1
(en)
|
1992-03-05 |
1993-09-16 |
Board Of Regents, The University Of Texas System |
Diagnostic and/or therapeutic agents, targeted to neovascular endothelial cells
|
|
US6749853B1
(en)
|
1992-03-05 |
2004-06-15 |
Board Of Regents, The University Of Texas System |
Combined methods and compositions for coagulation and tumor treatment
|
|
US5965132A
(en)
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
US6096289A
(en)
|
1992-05-06 |
2000-08-01 |
Immunomedics, Inc. |
Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
|
|
EP0672068A4
(en)
|
1992-09-25 |
1997-02-26 |
Commw Scient Ind Res Org |
TARGET MOLECULES BINDING POLYPEPTIDES.
|
|
AU5322494A
(en)
|
1992-10-02 |
1994-04-26 |
Trustees Of Dartmouth College |
Bispecific reagents for redirected targeting of low density lipoprotein
|
|
WO1994009817A1
(en)
|
1992-11-04 |
1994-05-11 |
City Of Hope |
Novel antibody construct
|
|
EP1757695A3
(en)
|
1992-11-05 |
2008-02-27 |
Sloan Kettering Institute For Cancer Research |
Prostate-specific membrane antigen
|
|
AU5670194A
(en)
|
1992-11-20 |
1994-06-22 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
|
US5376249A
(en)
|
1992-11-25 |
1994-12-27 |
Perseptive Biosystems, Inc. |
Analysis utilizing isoelectric focusing
|
|
GB9225453D0
(en)
|
1992-12-04 |
1993-01-27 |
Medical Res Council |
Binding proteins
|
|
JP3720353B2
(ja)
|
1992-12-04 |
2005-11-24 |
メディカル リサーチ カウンシル |
多価および多重特異性の結合タンパク質、それらの製造および使用
|
|
DE69327229T2
(de)
|
1992-12-11 |
2000-03-30 |
The Dow Chemical Co., Midland |
Multivalente einkettige Antikörper
|
|
US5861156A
(en)
|
1993-01-08 |
1999-01-19 |
Creative Biomolecules |
Methods of delivering agents to target cells
|
|
US5773253A
(en)
|
1993-01-22 |
1998-06-30 |
Bristol-Myers Squibb Company |
MYPPPY variants of CTL A4 and uses thereof
|
|
US6482919B2
(en)
|
1993-02-01 |
2002-11-19 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
|
KR100310739B1
(ko)
|
1993-02-04 |
2002-05-30 |
알란 스코브 |
단백질재생을위한개선된방법
|
|
US5705614A
(en)
|
1993-04-09 |
1998-01-06 |
Chiron Corporation |
Methods of producing antigen forks
|
|
US5869049A
(en)
|
1993-09-02 |
1999-02-09 |
Trustees Of Dartmouth College |
Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists
|
|
KR100398819B1
(ko)
|
1993-09-02 |
2004-02-05 |
트러스티스 오브 다트마우스 칼리지 |
gp39길항제를포함하는약제조성물
|
|
WO1995006666A1
(en)
|
1993-09-02 |
1995-03-09 |
Trustees Of Dartmouth College |
Anti-gp39 antibodies and uses therefor
|
|
EP0720624B1
(en)
|
1993-09-22 |
1998-11-25 |
Medical Research Council |
Retargeting antibodies
|
|
WO1996026272A1
(en)
|
1995-02-24 |
1996-08-29 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen and uses thereof
|
|
GB9324807D0
(en)
|
1993-12-03 |
1994-01-19 |
Cancer Res Campaign Tech |
Tumour antibody
|
|
DE4421391C1
(de)
|
1994-06-18 |
1995-11-30 |
Gsf Forschungszentrum Umwelt |
Verwendung von Antikörpern gegen T-Zellen zur verlängerten Immunsuppression
|
|
US6465253B1
(en)
|
1994-09-08 |
2002-10-15 |
Genvec, Inc. |
Vectors and methods for gene transfer to cells
|
|
US5846782A
(en)
|
1995-11-28 |
1998-12-08 |
Genvec, Inc. |
Targeting adenovirus with use of constrained peptide motifs
|
|
US5965541A
(en)
|
1995-11-28 |
1999-10-12 |
Genvec, Inc. |
Vectors and methods for gene transfer to cells
|
|
US5962311A
(en)
|
1994-09-08 |
1999-10-05 |
Genvec, Inc. |
Short-shafted adenoviral fiber and its use
|
|
US5559099A
(en)
|
1994-09-08 |
1996-09-24 |
Genvec, Inc. |
Penton base protein and methods of using same
|
|
US5541087A
(en)
|
1994-09-14 |
1996-07-30 |
Fuji Immunopharmaceuticals Corporation |
Expression and export technology of proteins as immunofusins
|
|
US5688690A
(en)
|
1994-09-16 |
1997-11-18 |
The Wistar Institute Of Anatomy And Biology |
Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
GB9504344D0
(en)
|
1995-03-03 |
1995-04-19 |
Unilever Plc |
Antibody fragment production
|
|
US5837281A
(en)
|
1995-03-17 |
1998-11-17 |
Takeda Chemical Industries, Ltd. |
Stabilized interface for iontophoresis
|
|
US5747035A
(en)
|
1995-04-14 |
1998-05-05 |
Genentech, Inc. |
Polypeptides with increased half-life for use in treating disorders involving the LFA-1 receptor
|
|
US6096871A
(en)
|
1995-04-14 |
2000-08-01 |
Genentech, Inc. |
Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
US5830478A
(en)
|
1995-06-07 |
1998-11-03 |
Boston Biomedical Research Institute |
Method for delivering functional domains of diphtheria toxin to a cellular target
|
|
WO1997014719A1
(en)
|
1995-10-16 |
1997-04-24 |
Unilever N.V. |
A bifunctional or bivalent antibody fragment analogue
|
|
ATE265532T1
(de)
|
1995-10-19 |
2004-05-15 |
Bristol Myers Squibb Co |
Monoklonaler antikörper br110 und dessen anwendung
|
|
US6962981B1
(en)
|
1996-03-25 |
2005-11-08 |
Medarex, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
|
US7381407B1
(en)
|
1996-03-25 |
2008-06-03 |
Medarex, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
|
ATE318147T1
(de)
|
1996-03-25 |
2006-03-15 |
Medarex Inc |
Spezifische monoklonale antikörperfür die extrazelluläre domäne von protasta-spezifischem membranantigen
|
|
US6150508A
(en)
|
1996-03-25 |
2000-11-21 |
Northwest Biotherapeutics, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
JP2000503773A
(ja)
|
1996-05-23 |
2000-03-28 |
ユニリーバー・ナームローゼ・ベンノートシヤープ |
特異的結合アッセイの改良
|
|
JP2000515735A
(ja)
|
1996-07-03 |
2000-11-28 |
ジェネンテック インコーポレーテッド |
肝細胞成長因子レセプターアゴニスト
|
|
GB9712818D0
(en)
|
1996-07-08 |
1997-08-20 |
Cambridge Antibody Tech |
Labelling and selection of specific binding molecules
|
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
WO1998016254A1
(en)
|
1996-10-17 |
1998-04-23 |
Immunomedics, Inc. |
Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
|
|
JP4663824B2
(ja)
|
1996-12-31 |
2011-04-06 |
ハイ スループット ジェノミクス インコーポレイテッド |
多重化分子分析装置および方法
|
|
EP2343085B1
(en)
|
1997-03-10 |
2014-12-10 |
The Regents of The University of California |
Antibody against prostate stem cell antigen (PSCA)
|
|
US6258939B1
(en)
|
1997-03-10 |
2001-07-10 |
The Regents Of The University Of California |
PSCA antibodies and hybridomas producing them
|
|
US6261789B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Methods for detecting the presence of a PSCA protein using PSCA antibodies
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
US6960443B2
(en)
|
1997-03-10 |
2005-11-01 |
The Regents Of The University Of California |
Methods of detecting prostate stem cell antigen in cancer
|
|
US6261791B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Method for diagnosing cancer using specific PSCA antibodies
|
|
US20080318254A9
(en)
|
1997-03-10 |
2008-12-25 |
The Regents Of The University Of California |
PSCA antibodies and hybridomas producing them
|
|
AU6914098A
(en)
|
1997-04-03 |
1998-10-30 |
Universite Laval |
Transgenic expression in genital tract and sexual accessory glands
|
|
DE69831224T2
(de)
|
1997-05-02 |
2006-03-23 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Immuntoxine, die ein onc protein enthalten, gegen bösartige zellen
|
|
WO1999002567A2
(en)
|
1997-07-08 |
1999-01-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods for producing homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
US6977074B2
(en)
|
1997-07-10 |
2005-12-20 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
US6994851B1
(en)
|
1997-07-10 |
2006-02-07 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
AU9375698A
(en)
|
1997-09-03 |
1999-03-22 |
Immunomedics Inc. |
Fluorination of proteins and peptides for f-18 positron emission tomography
|
|
US6030792A
(en)
|
1997-11-13 |
2000-02-29 |
Pfizer Inc |
Assays for measurement of protein fragments in biological media
|
|
US6709844B1
(en)
|
2000-11-16 |
2004-03-23 |
Mannkind Corporation |
Avoidance of undesirable replication intermediates in plasmid propagation
|
|
DE19911329A1
(de)
|
1998-03-27 |
2000-09-21 |
Benes Ivan Friedrich |
Humantherapeutisch anwendbares Radioimmunkonjugat und Verfahren zu seiner Herstellung
|
|
CZ121599A3
(cs)
|
1998-04-09 |
1999-10-13 |
Aventis Pharma Deutschland Gmbh |
Jednořetězcová molekula vázající několik antigenů, způsob její přípravy a léčivo obsahující tuto molekulu
|
|
AU3657899A
(en)
|
1998-04-20 |
1999-11-08 |
James E. Bailey |
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
|
|
US6200765B1
(en)
|
1998-05-04 |
2001-03-13 |
Pacific Northwest Cancer Foundation |
Non-invasive methods to detect prostate cancer
|
|
US6071490A
(en)
|
1998-05-07 |
2000-06-06 |
Immunomedics, Inc. |
Position emission tomography using gallium-68 chelates
|
|
EP1079862B1
(en)
|
1998-05-20 |
2010-07-07 |
Immunomedics, Inc. |
Therapeutics using a bispecific anti-hla class ii invariant chain x anti-pathogen antibody
|
|
US20060052321A1
(en)
|
2002-04-05 |
2006-03-09 |
Raitano Arthur B |
Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
|
|
AU757698C
(en)
|
1998-06-01 |
2004-04-08 |
Agensys, Inc. |
Novel serpentine transmembrane antigens expressed in human cancers and uses thereof
|
|
US20040141975A1
(en)
|
1998-06-01 |
2004-07-22 |
Raitano Arthur B. |
Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
|
|
AU750414B2
(en)
|
1998-07-13 |
2002-07-18 |
Board Of Regents, The University Of Texas System |
Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids
|
|
WO2000014234A1
(en)
|
1998-09-08 |
2000-03-16 |
Urocor, Inc. |
Prostate specific promoter and regulation of gene expression
|
|
US6361774B1
(en)
|
1999-09-17 |
2002-03-26 |
Immunomedics, Inc. |
Methods and compositions for increasing the target-specific toxicity of a chemotherapy drug
|
|
CA2344655A1
(en)
|
1998-09-29 |
2000-04-06 |
The Uab Research Foundation |
Immunomodulation by genetic modification of dendritic cells and b-cells
|
|
US6642007B1
(en)
|
1998-11-02 |
2003-11-04 |
Pfizer Inc. |
Assays for measurement of type II collagen fragments in urine
|
|
WO2000034461A2
(en)
|
1998-12-10 |
2000-06-15 |
Board Of Regents, The University Of Texas System |
Compositions and methods of modulating cholesterol metabolism
|
|
DE60039354D1
(de)
|
1999-04-09 |
2008-08-14 |
Univ Zuerich |
Verfahren zur Stabilisierung von chimären Immunoglobulinen oder Immunoglobulinfragmenten und stabilisiertes Anti-EGP-2-scFv-Fragment
|
|
WO2000062063A1
(en)
|
1999-04-13 |
2000-10-19 |
Northwest Biotherapeutics, Inc. |
Methods for the diagnosis and treatment of metastatic prostate tumors
|
|
US6703020B1
(en)
|
1999-04-28 |
2004-03-09 |
Board Of Regents, The University Of Texas System |
Antibody conjugate methods for selectively inhibiting VEGF
|
|
IL145941A
(en)
|
1999-04-28 |
2007-08-19 |
Univ Texas |
Compositions and methods for cancer treatment by selectively inhibiting vegf
|
|
GB9915653D0
(en)
|
1999-07-06 |
1999-09-01 |
Bruce Terry |
Hose clamp
|
|
WO2001009303A2
(en)
|
1999-07-30 |
2001-02-08 |
Vical Inc. |
Flt-3 LIGAND-ENCODING POLYNUCLEOTIDE AS A POLYNUCLEOTIDE-BASED VACCINE ENHANCER
|
|
KR100510795B1
(en)
|
1999-08-31 |
2005-08-30 |
|
Compositions and Methods for the Treatment of Tumor
|
|
US6342587B1
(en)
|
1999-10-22 |
2002-01-29 |
Ludwig Institute For Cancer Research |
A33 antigen specific immunoglobulin products and uses thereof
|
|
US6346249B1
(en)
|
1999-10-22 |
2002-02-12 |
Ludwig Institute For Cancer Research |
Methods for reducing the effects of cancers that express A33 antigen using A33 antigen specific immunoglobulin products
|
|
US6824780B1
(en)
*
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
BR0015224A
(pt)
*
|
1999-10-29 |
2002-07-09 |
Genentech Inc |
Anticorpo anti-antìgeno de célula estaminal prostática (psca) isolado, anticorpo monoclonal anti-psca, ácido nucleico isolado, vetor de expressão, célula, célula hospedeira, método de produção de anticorpo, composição método in vitro para matar uma célula cancerosa que expresse psca, uso de uma anticorpo monoclonal anti-psca e artigo industrializado
|
|
PL357448A1
(en)
*
|
2000-02-25 |
2004-07-26 |
The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services |
Anti-egfrviii scfvs with improved cytotoxicity and yield, immunotoxins based thereon, and methods of use thereof
|
|
WO2001071005A2
(en)
|
2000-03-24 |
2001-09-27 |
Micromet Ag |
Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex
|
|
US6573096B1
(en)
|
2000-04-01 |
2003-06-03 |
The Research Foundation At State University Of New York |
Compositions and methods for inhibition of cancer invasion and angiogenesis
|
|
AU2001247616B2
(en)
|
2000-04-11 |
2007-06-14 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
|
US6861234B1
(en)
|
2000-04-28 |
2005-03-01 |
Mannkind Corporation |
Method of epitope discovery
|
|
EP1276896B1
(en)
|
2000-04-28 |
2010-07-21 |
Mannkind Corporation |
Epitope synchronization in antigen presenting cells
|
|
US6375991B1
(en)
|
2000-09-08 |
2002-04-23 |
Albemarle Corporation |
Production of concentrated biocidal solutions
|
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
|
WO2003008537A2
(en)
|
2001-04-06 |
2003-01-30 |
Mannkind Corporation |
Epitope sequences
|
|
NZ581474A
(en)
|
2001-08-03 |
2011-04-29 |
Glycart Biotechnology Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
|
US7494646B2
(en)
|
2001-09-06 |
2009-02-24 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
|
AU2002336446B2
(en)
|
2001-09-06 |
2008-03-06 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
|
|
KR100988949B1
(ko)
|
2001-10-25 |
2010-10-20 |
제넨테크, 인크. |
당단백질 조성물
|
|
DE60238864D1
(de)
|
2001-11-07 |
2011-02-17 |
Mankind Corp |
Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption
|
|
US20040018519A1
(en)
|
2001-11-16 |
2004-01-29 |
Wright ,Jr. George L |
Methods and devices for quantitative detection of prostate specific membrane antigen and other prostatic markers
|
|
JP4035845B2
(ja)
|
2001-12-10 |
2008-01-23 |
株式会社グリーンペプタイド |
腫瘍抗原
|
|
WO2003062375A2
(en)
|
2001-12-19 |
2003-07-31 |
Genentech, Inc. |
Stabilizing polypeptides which have been exposed to urea
|
|
CA2473144C
(en)
|
2002-02-05 |
2013-05-28 |
Genentech, Inc. |
Protein purification
|
|
DK1501369T3
(en)
|
2002-04-26 |
2015-09-28 |
Genentech Inc |
Non-affinity purification of proteins
|
|
EP2365004B1
(en)
|
2002-06-21 |
2016-01-06 |
Johns Hopkins University School of Medicine |
Membrane associated tumor endothelium markers
|
|
US9809654B2
(en)
|
2002-09-27 |
2017-11-07 |
Vaccinex, Inc. |
Targeted CD1d molecules
|
|
US7820166B2
(en)
|
2002-10-11 |
2010-10-26 |
Micromet Ag |
Potent T cell modulating molecules
|
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
|
EP2270048B1
(en)
*
|
2002-12-24 |
2015-11-11 |
Rinat Neuroscience Corp. |
Anti-NGF antibodies and methods using same
|
|
CZ308720B6
(cs)
|
2003-01-22 |
2021-03-24 |
Roche Glycart Ag |
Fúzní konstrukty a jejich použití pro přípravu protilátek se zvýšenou vazebnou afinitou k receptorům Fc a efektorovou funkcí
|
|
US7453436B2
(en)
*
|
2003-03-21 |
2008-11-18 |
Ruiz David M |
Hand-held on-screen control device
|
|
US20050026178A1
(en)
|
2003-03-28 |
2005-02-03 |
Marit Nilsen-Hamilton |
Allosteric probes and methods
|
|
GB0308988D0
(en)
|
2003-04-17 |
2003-05-28 |
Univ Singapore |
Molecule
|
|
KR101291787B1
(ko)
|
2003-05-30 |
2013-08-07 |
어젠시스 인코포레이티드 |
전립선 줄기 세포 항원 (psca) 변이체 및 그의서브서열
|
|
US7595379B2
(en)
|
2003-05-30 |
2009-09-29 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
|
US7541442B2
(en)
*
|
2003-05-30 |
2009-06-02 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
|
DK1629011T3
(da)
|
2003-05-31 |
2010-05-03 |
Micromet Ag |
Humane anti-humane-DC3-bindingsmolekyler
|
|
US7700097B2
(en)
|
2003-06-27 |
2010-04-20 |
Biogen Idec Ma Inc. |
Purification and preferential synthesis of binding molecules
|
|
HUE029951T2
(en)
|
2003-07-28 |
2017-04-28 |
Genentech Inc |
Reduction of Protein A Dissolution in Protein A Affinity Chromatography
|
|
GB0321805D0
(en)
|
2003-09-18 |
2003-10-15 |
Univ Wales Medicine |
Human tumour growth patterns
|
|
US7524813B2
(en)
|
2003-10-10 |
2009-04-28 |
Novo Nordisk Health Care Ag |
Selectively conjugated peptides and methods of making the same
|
|
ZA200601699B
(en)
|
2003-10-16 |
2007-05-30 |
Micromet Ag |
Multispecific deimmunized CD3-binders
|
|
ES2428358T3
(es)
|
2003-10-17 |
2013-11-07 |
Novo Nordisk A/S |
Terapia de combinación
|
|
ITPD20030264A1
(it)
|
2003-10-30 |
2005-04-30 |
Xeptagen Spa |
Metodo di diagnosi altamente specifico per neoplasie
|
|
EP3434275A1
(en)
|
2003-11-06 |
2019-01-30 |
Seattle Genetics, Inc. |
Assay for cancer cells based on the use of auristatin conjugates with antibodies
|
|
US7235641B2
(en)
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
|
EP1704228B1
(en)
|
2004-01-16 |
2012-04-11 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Immunokinases
|
|
BRPI0507649A
(pt)
|
2004-02-16 |
2007-07-10 |
Micromet Ag |
molécula de ligação biespecìfica, seqüência de ácido nucléico, vetor, processo para a produção da molécula de ligação biespecìfica, composição, uso da molécula de ligação biespecìfica na preparação da composição farmacêutica, e kit
|
|
EP1718667B1
(en)
|
2004-02-23 |
2013-01-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
WO2005101017A1
(en)
|
2004-04-07 |
2005-10-27 |
Genentech, Inc. |
Mass spectrometry of antibody conjugates
|
|
CA2568238C
(en)
|
2004-04-12 |
2013-10-15 |
Medical College Of Ohio |
Methods and compositions for assaying analytes
|
|
NZ550816A
(en)
|
2004-04-22 |
2009-12-24 |
Agensys Inc |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
|
MXPA06014065A
(es)
|
2004-06-01 |
2007-01-31 |
Genentech Inc |
Conjugados de droga-anticuerpo y metodos.
|
|
US20080227736A1
(en)
|
2004-06-03 |
2008-09-18 |
Regents Of The University Of California, |
Targeting Pseudotyped Retroviral Vectors
|
|
US20060159689A1
(en)
|
2004-06-17 |
2006-07-20 |
Chih-Sheng Chiang |
Combinations of tumor-associated antigens in diagnostics for various types of cancers
|
|
US20060008468A1
(en)
|
2004-06-17 |
2006-01-12 |
Chih-Sheng Chiang |
Combinations of tumor-associated antigens in diagnostics for various types of cancers
|
|
US7323682B2
(en)
*
|
2004-07-02 |
2008-01-29 |
Thermo Finnigan Llc |
Pulsed ion source for quadrupole mass spectrometer and method
|
|
EA010374B1
(ru)
|
2004-07-16 |
2008-08-29 |
Микромет Аг |
Полипептиды с повышенной экспрессией
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
ES2579805T3
(es)
|
2004-09-23 |
2016-08-16 |
Genentech, Inc. |
Anticuerpos y conjugados modificados por ingeniería genética con cisteína
|
|
GB0422431D0
(en)
*
|
2004-10-08 |
2004-11-10 |
Affitech As |
Method
|
|
US20070134243A1
(en)
|
2004-12-01 |
2007-06-14 |
Gazzard Lewis J |
Antibody drug conjugates and methods
|
|
US7947839B2
(en)
|
2004-12-01 |
2011-05-24 |
Genentech, Inc. |
Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use
|
|
CA2491067A1
(en)
|
2004-12-24 |
2006-06-24 |
Stichting Katholieke Universiteit |
Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
|
|
EP1874822A1
(en)
|
2005-04-14 |
2008-01-09 |
Agensys, Inc. |
Antibodies and related molecules that bind to psca proteins
|
|
CA2606018A1
(en)
|
2005-04-28 |
2006-11-02 |
Ventana Medical Systems, Inc. |
Nanoparticle conjugates
|
|
US8088908B2
(en)
*
|
2005-05-10 |
2012-01-03 |
City Of Hope |
Humanized anti-prostate stem cell antigen monoclonal antibody
|
|
GB2426581A
(en)
|
2005-05-27 |
2006-11-29 |
Univ Nottingham |
Immunoassay methods
|
|
EP2295080A3
(en)
|
2005-07-25 |
2011-06-22 |
Emergent Product Development Seattle, LLC |
B-cell reduction using CD37-specific and CD20-specific binding molecules
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
WO2007100385A2
(en)
|
2005-10-31 |
2007-09-07 |
Genentech, Inc. |
Macrocyclic depsipeptide antibody-drug conjugates and methods
|
|
US20070212331A1
(en)
|
2006-03-07 |
2007-09-13 |
Baldassare Joseph J |
Methods and compositions for selectively killing cells
|
|
EP1996716B1
(en)
*
|
2006-03-20 |
2011-05-11 |
The Regents of the University of California |
Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
|
|
EP2001907A2
(en)
|
2006-03-21 |
2008-12-17 |
Wyeth a Corporation of the State of Delaware |
Methods and compositions for antagonism of rage
|
|
CA2648099C
(en)
|
2006-03-31 |
2012-05-29 |
The Brigham And Women's Hospital, Inc |
System for targeted delivery of therapeutic agents
|
|
US7566276B2
(en)
|
2006-04-14 |
2009-07-28 |
Dogleg Right Corporation |
Multi-piece putter head having an insert
|
|
WO2007137117A2
(en)
|
2006-05-17 |
2007-11-29 |
Massachusetts Institute Of Technology |
Aptamer-directed drug delivery
|
|
US8574848B2
(en)
|
2006-09-13 |
2013-11-05 |
Oncimmune Ltd. |
Immunoassay methods
|
|
RU2450832C2
(ru)
|
2006-10-25 |
2012-05-20 |
Конинклейке Филипс Электроникс Н.В. |
Контрастные вещества для детекции рака предстательной железы
|
|
WO2008079280A1
(en)
|
2006-12-21 |
2008-07-03 |
Millipore Corporation |
Purification of proteins
|
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
CA2682605A1
(en)
|
2007-04-18 |
2008-10-30 |
Zymogenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
|
EP2167537A2
(en)
|
2007-07-03 |
2010-03-31 |
Dako Denmark A/S |
Compiled methods for analysing and sorting samples
|
|
US8940298B2
(en)
|
2007-09-04 |
2015-01-27 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting and detection
|
|
US10611818B2
(en)
|
2007-09-27 |
2020-04-07 |
Agilent Technologies, Inc. |
MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
|
|
US7867483B2
(en)
|
2007-10-18 |
2011-01-11 |
Bn Immunotherapeutics, Inc. |
Use of MVA to treat prostate cancer
|
|
US20090169613A1
(en)
|
2007-11-09 |
2009-07-02 |
Reznik Boris N |
Targeting of tumor stem cells through selective silencing of boris expression
|
|
US9107858B2
(en)
|
2007-12-05 |
2015-08-18 |
Wisconsin Alumni Research Foundation |
Dendritic cell targeting compositions and uses thereof
|
|
US8043830B2
(en)
|
2008-02-01 |
2011-10-25 |
The Regents Of The University Of California |
Biotin-ligase system for secretion of biotinylated protein
|
|
US8742076B2
(en)
|
2008-02-01 |
2014-06-03 |
Genentech, Inc. |
Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
|
|
TW200947474A
(en)
|
2008-05-05 |
2009-11-16 |
Ren-Huan Pan |
Manufacturing equipment and method of quadratic arc alignment dua-turret formation center, and miniature milliohm current sensors manufactured thereof
|
|
EP2277044B1
(en)
|
2008-05-13 |
2015-06-17 |
Genentech, Inc. |
Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry
|
|
WO2010009124A2
(en)
|
2008-07-15 |
2010-01-21 |
Genentech, Inc. |
Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
|
|
US20100069616A1
(en)
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
|
AU2009288561B2
(en)
|
2008-09-08 |
2014-07-24 |
Conocophillips Company |
System for incondensable component separation in a liquefied natural gas facility
|
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
|
SG194399A1
(en)
|
2008-10-01 |
2013-11-29 |
Amgen Res Munich Gmbh |
Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxcd3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody
|
|
US20110318380A1
(en)
|
2008-10-01 |
2011-12-29 |
Dako Denmark A/S |
MHC Multimers in Cancer Vaccines and Immune Monitoring
|
|
WO2010037397A1
(en)
|
2008-10-01 |
2010-04-08 |
Dako Denmark A/S |
Mhc multimers in cmv immune monitoring
|
|
WO2010043927A1
(en)
|
2008-10-13 |
2010-04-22 |
Xeptagen Spa |
Method for the preparation of immunoconjugates and use thereof
|
|
CN102308004A
(zh)
|
2008-10-30 |
2012-01-04 |
卡里斯生命科学卢森堡控股有限责任公司 |
评价rna图案的方法
|
|
CA2743211A1
(en)
|
2008-11-12 |
2010-05-20 |
Caris Life Sciences Luxembourg Holdings, S.A.R.L. |
Methods and systems of using exosomes for determining phenotypes
|
|
WO2010057047A1
(en)
|
2008-11-13 |
2010-05-20 |
Trubion Pharmaceutics, Inc. |
Cd37 immunotherapeutic combination therapies and uses thereof
|
|
SG171764A1
(en)
|
2008-12-16 |
2011-07-28 |
Millipore Corp |
Purification of proteins
|
|
CN102265059B
(zh)
|
2008-12-25 |
2013-08-07 |
东海橡塑工业株式会社 |
流体封入式隔振装置
|
|
WO2010081173A2
(en)
|
2009-01-12 |
2010-07-15 |
Cytomx Therapeutics, Llc |
Modified antibody compositions, methods of making and using thereof
|
|
WO2010102195A2
(en)
|
2009-03-06 |
2010-09-10 |
The Johns Hopkins University |
Annexin a11 and associated genes as biomarkers for cancer
|
|
CA2756493C
(en)
|
2009-03-24 |
2019-07-02 |
Biocept, Inc. |
Devices and methods of cell capture and analysis
|
|
AU2010245011B2
(en)
|
2009-04-27 |
2015-09-03 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
|
KR20120034679A
(ko)
|
2009-05-28 |
2012-04-12 |
글락소 그룹 리미티드 |
Il-13 결합 단백질
|
|
EP2448966B1
(en)
|
2009-07-03 |
2018-11-14 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
|
TWM383852U
(en)
|
2009-07-13 |
2010-07-01 |
Speedtech Corp |
An improvement of the universal serial bus connector
|
|
EP2471556A4
(en)
|
2009-10-05 |
2015-06-03 |
Canon Kk |
CONTRASTANT FOR PHOTOACUSTIC IMAGING AND PROCESS FOR PHOTOACUSTIC IMAGING THEREWITH
|
|
MX337600B
(es)
|
2009-12-02 |
2016-03-11 |
Imaginab Inc |
Minicuerpos j591 y diacuerpos-cys para apuntar con especificidad de objetivo a un antigeno de membrana especifico para prostata de humano (psma) y metodos para su uso.
|
|
US20110142811A1
(en)
|
2009-12-16 |
2011-06-16 |
Deutsches Krebsforschungszentrum |
Measles virus for the elimination of unwanted cell populations
|
|
WO2011075786A1
(en)
|
2009-12-23 |
2011-06-30 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them 2
|
|
SI2519543T1
(sl)
|
2009-12-29 |
2016-08-31 |
Emergent Product Development Seattle, Llc |
Beljakovine, ki se vežejo s heterodimeri in njihova uporaba
|
|
US9128101B2
(en)
|
2010-03-01 |
2015-09-08 |
Caris Life Sciences Switzerland Holdings Gmbh |
Biomarkers for theranostics
|