JP2010536365A - 前立腺癌の治療及び診断の標的遺伝子のための、ｐｋｉｂ及びｎａａｌａｄｌ２ - Google Patents

前立腺癌の治療及び診断の標的遺伝子のための、ｐｋｉｂ及びｎａａｌａｄｌ２ Download PDF

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JP2010536365A
JP2010536365A JP2010521579A JP2010521579A JP2010536365A JP 2010536365 A JP2010536365 A JP 2010536365A JP 2010521579 A JP2010521579 A JP 2010521579A JP 2010521579 A JP2010521579 A JP 2010521579A JP 2010536365 A JP2010536365 A JP 2010536365A
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pkib
seq
double
naaladl2
prostate cancer
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JP2010536365A5 (enExample
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祐輔 中村
英刀 中川
修一 中鶴
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Oncotherapy Science Inc
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Oncotherapy Science Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

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  • Wood Science & Technology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
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  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2010521579A 2007-08-24 2008-08-20 前立腺癌の治療及び診断の標的遺伝子のための、ｐｋｉｂ及びｎａａｌａｄｌ２ Withdrawn JP2010536365A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95785307P 2007-08-24 2007-08-24
US3603008P 2008-03-12 2008-03-12
PCT/JP2008/065234 WO2009028521A1 (en) 2007-08-24 2008-08-20 Pkib and naaladl2 for target genes of prostate cancer therapy and diagnosis

Publications (2)

Publication Number Publication Date
JP2010536365A true JP2010536365A (ja) 2010-12-02
JP2010536365A5 JP2010536365A5 (enExample) 2011-10-06

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JP2010521579A Withdrawn JP2010536365A (ja) 2007-08-24 2008-08-20 前立腺癌の治療及び診断の標的遺伝子のための、ｐｋｉｂ及びｎａａｌａｄｌ２

Country Status (10)

Country Link
US (1) US20120022128A1 (enExample)
EP (1) EP2195425A4 (enExample)
JP (1) JP2010536365A (enExample)
KR (1) KR20100075452A (enExample)
CN (1) CN101855346A (enExample)
BR (1) BRPI0815757A2 (enExample)
CA (1) CA2697512A1 (enExample)
RU (1) RU2010111116A (enExample)
TW (1) TW200920405A (enExample)
WO (1) WO2009028521A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016511767A (ja) * 2013-02-25 2016-04-21 オックスフォード ビオトヘラペウトイクス エルティーディー． 治療的及び診断的標的としての不活性Ｎ−アセチル化−α−結合型酸性ジペプチダーゼ−様タンパク質２（ＮＡＡＬＡＤＬ２）

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Publication number Priority date Publication date Assignee Title
WO2011014740A2 (en) * 2009-07-31 2011-02-03 Chromocell Corporation Methods and composition for identifying and validating modulators of cell fate
KR101164645B1 (ko) * 2011-10-07 2012-07-20 대한민국 Ｇｃｐⅱ 돌연변이를 함유하는 알츠하이머 예방 및 치료용 약학적 조성물
GB201304612D0 (en) * 2013-03-14 2013-05-01 Cancer Rec Tech Ltd Diagnostic and prognostic biomarkers for prostate cancer and other disorders
DK3013986T3 (en) * 2014-01-03 2017-02-27 Koninklijke Philips Nv ASSESSMENT OF PI3K CELL SIGNALING ACTIVITY ACTIVITIES USING MATHEMATICAL MODELING OF TARGET EXPRESSION
KR101824303B1 (ko) 2015-08-06 2018-01-31 부경대학교 산학협력단 종이형 전립선암 진단센서, 이의 제조방법, 및 이를 이용한 전립선암 진단방법
CN114177296B (zh) * 2021-12-16 2023-05-26 上海交通大学医学院附属第九人民医院 Mpc的过表达或活性提高在制备预防和/或治疗前列腺癌的药物中的应用

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016511767A (ja) * 2013-02-25 2016-04-21 オックスフォード ビオトヘラペウトイクス エルティーディー． 治療的及び診断的標的としての不活性Ｎ−アセチル化−α−結合型酸性ジペプチダーゼ−様タンパク質２（ＮＡＡＬＡＤＬ２）

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KR20100075452A (ko) 2010-07-02
EP2195425A1 (en) 2010-06-16
EP2195425A4 (en) 2011-01-19
RU2010111116A (ru) 2011-09-27
TW200920405A (en) 2009-05-16
CN101855346A (zh) 2010-10-06
BRPI0815757A2 (pt) 2015-02-18
US20120022128A1 (en) 2012-01-26
WO2009028521A1 (en) 2009-03-05
CA2697512A1 (en) 2009-03-05

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