JP2010535798A5 - - Google Patents

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Publication number
JP2010535798A5
JP2010535798A5 JP2010520269A JP2010520269A JP2010535798A5 JP 2010535798 A5 JP2010535798 A5 JP 2010535798A5 JP 2010520269 A JP2010520269 A JP 2010520269A JP 2010520269 A JP2010520269 A JP 2010520269A JP 2010535798 A5 JP2010535798 A5 JP 2010535798A5
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JP
Japan
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JP2010520269A
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JP2010535798A (ja
JP5298128B2 (ja
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Priority claimed from PCT/US2008/072267 external-priority patent/WO2009020990A1/en
Publication of JP2010535798A publication Critical patent/JP2010535798A/ja
Publication of JP2010535798A5 publication Critical patent/JP2010535798A5/ja
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Publication of JP5298128B2 publication Critical patent/JP5298128B2/ja
Expired - Fee Related legal-status Critical Current
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JP2010520269A 2007-08-08 2008-08-06 癌の治療用のIGF−1R阻害剤としての2−[(2−{フェニルアミノ}−1H−ピロロ[2,3−d]ピリミジン−4−イル)アミノ]ベンズアミド誘導体 Expired - Fee Related JP5298128B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95464907P 2007-08-08 2007-08-08
US60/954,649 2007-08-08
US3008208P 2008-02-20 2008-02-20
US61/030,082 2008-02-20
PCT/US2008/072267 WO2009020990A1 (en) 2007-08-08 2008-08-06 2- [ (2-{phenylamino}-1h-pyrrolo [2, 3-d] pyrimidin-4-yl) amino] benzamide derivatives as igf-1r inhibitors for the treatment of cancer

Publications (3)

Publication Number Publication Date
JP2010535798A JP2010535798A (ja) 2010-11-25
JP2010535798A5 true JP2010535798A5 (ja) 2011-03-03
JP5298128B2 JP5298128B2 (ja) 2013-09-25

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ID=39797927

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010520269A Expired - Fee Related JP5298128B2 (ja) 2007-08-08 2008-08-06 癌の治療用のIGF−1R阻害剤としての2−[(2−{フェニルアミノ}−1H−ピロロ[2,3−d]ピリミジン−4−イル)アミノ]ベンズアミド誘導体

Country Status (10)

Country Link
US (1) US7981903B2 (ja)
EP (1) EP2188292B1 (ja)
JP (1) JP5298128B2 (ja)
CN (1) CN101827848B (ja)
AR (1) AR068054A1 (ja)
BR (1) BRPI0814777A2 (ja)
CL (1) CL2008002319A1 (ja)
ES (1) ES2424977T3 (ja)
RU (1) RU2472797C2 (ja)
WO (1) WO2009020990A1 (ja)

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CN104854101B (zh) * 2012-11-06 2018-05-01 上海复尚慧创医药研究有限公司 Alk激酶抑制剂
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
CN117486865A (zh) 2013-07-11 2024-02-02 艾森医药公司 嘧啶衍生物作为激酶抑制剂
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US9957270B2 (en) 2014-03-13 2018-05-01 Agency For Science, Technology And Research Fused pyrimidine-based hydroxamate derivatives
HUE053654T2 (hu) 2014-03-26 2021-07-28 Astex Therapeutics Ltd FGFR- és CMET-inhibitorok kombinációi a rák kezelésére
JO3512B1 (ar) 2014-03-26 2020-07-05 Astex Therapeutics Ltd مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
RU2715893C2 (ru) 2014-03-26 2020-03-04 Астекс Терапьютикс Лтд Комбинации ингибитора fgfr и ингибитора igf1r
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KR102548191B1 (ko) * 2018-04-09 2023-06-28 상하이테크 유니버시티 표적 단백질 분해 화합물, 이의 항종양 응용, 이의 중간체 및 중간체의 응용
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CN110294721A (zh) * 2019-07-22 2019-10-01 安庆缘启医药科技有限公司 1-乙酰基-4-[3-(甲基氧基)-4-硝基苯基]哌嗪的合成工艺
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CN114230524A (zh) * 2021-12-28 2022-03-25 南通大学 (5-氟-2-苯胺嘧啶-4-基)氨基-n-羟基苯甲酰胺衍生物及其制备方法与应用
CN114031559A (zh) * 2021-12-28 2022-02-11 南通大学 基于芳基含氮杂环修饰的5-氟-嘧啶二胺苯甲酸酯及其制备方法与应用
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