JP2010533737A5 - - Google Patents
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- Publication number
- JP2010533737A5 JP2010533737A5 JP2010517201A JP2010517201A JP2010533737A5 JP 2010533737 A5 JP2010533737 A5 JP 2010533737A5 JP 2010517201 A JP2010517201 A JP 2010517201A JP 2010517201 A JP2010517201 A JP 2010517201A JP 2010533737 A5 JP2010533737 A5 JP 2010533737A5
- Authority
- JP
- Japan
- Prior art keywords
- vlp
- protein
- vzv
- influenza
- tegument
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108090000623 proteins and genes Proteins 0.000 claims 17
- 102000004169 proteins and genes Human genes 0.000 claims 17
- 241000701085 Human alphaherpesvirus 3 Species 0.000 claims 10
- 206010022000 influenza Diseases 0.000 claims 5
- 241000712461 unidentified influenza virus Species 0.000 claims 4
- 101710154606 Hemagglutinin Proteins 0.000 claims 3
- 102000005348 Neuraminidase Human genes 0.000 claims 3
- 108010006232 Neuraminidase Proteins 0.000 claims 3
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 3
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 3
- 101710176177 Protein A56 Proteins 0.000 claims 3
- 239000000185 hemagglutinin Substances 0.000 claims 3
- 239000011159 matrix material Substances 0.000 claims 3
- 230000001086 cytosolic effect Effects 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 108700010900 influenza virus proteins Proteins 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95070707P | 2007-07-19 | 2007-07-19 | |
| US97059207P | 2007-09-07 | 2007-09-07 | |
| US7183508P | 2008-05-20 | 2008-05-20 | |
| PCT/US2008/070636 WO2009012487A2 (en) | 2007-07-19 | 2008-07-21 | Chimeric varicella zoster virus-virus like particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010533737A JP2010533737A (ja) | 2010-10-28 |
| JP2010533737A5 true JP2010533737A5 (OSRAM) | 2011-08-11 |
Family
ID=40260107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517201A Withdrawn JP2010533737A (ja) | 2007-07-19 | 2008-07-21 | キメラ水痘帯状疱疹ウイルス−ウイルス様粒子 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20110008838A1 (OSRAM) |
| EP (3) | EP2176427A4 (OSRAM) |
| JP (1) | JP2010533737A (OSRAM) |
| CN (1) | CN101801411A (OSRAM) |
| CA (1) | CA2693899A1 (OSRAM) |
| CY (1) | CY1116583T1 (OSRAM) |
| DK (1) | DK2540312T3 (OSRAM) |
| ES (1) | ES2542644T3 (OSRAM) |
| HR (1) | HRP20150758T1 (OSRAM) |
| HU (1) | HUE025702T2 (OSRAM) |
| PL (1) | PL2540312T3 (OSRAM) |
| PT (1) | PT2540312E (OSRAM) |
| SI (1) | SI2540312T1 (OSRAM) |
| WO (2) | WO2009012487A2 (OSRAM) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| PL3067064T3 (pl) | 2008-12-09 | 2020-11-02 | Novavax, Inc. | Zmodyfikowane białka f rsv i sposoby ich wykorzystania |
| AU2010243489A1 (en) | 2009-05-01 | 2011-12-22 | Redbiotec Ag | Recombinant virus-like particles encoded by multi-gene vector |
| PL222497B1 (pl) | 2009-06-26 | 2016-08-31 | Inst Biochemii I Biofizyki Pan | Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej |
| CA2766899C (en) | 2009-07-02 | 2021-05-04 | Massachusetts Institute Of Technology | Compositions and methods for diagnosing and/or treating influenza infection |
| MX2012011300A (es) | 2010-03-30 | 2012-11-29 | Sinai School Medicine | Vacunas del virus de influenza y usos de las mismas. |
| JP2013541528A (ja) | 2010-09-21 | 2013-11-14 | マサチューセッツ インスティテュート オブ テクノロジー | ヒト適応ｈａポリペプチド、ワクチン、およびインフルエンザの処置 |
| AU2011312178B2 (en) | 2010-10-04 | 2016-05-12 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| TWI526539B (zh) * | 2010-12-22 | 2016-03-21 | 苜蓿股份有限公司 | 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp |
| WO2012106377A2 (en) * | 2011-01-31 | 2012-08-09 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof |
| IN2014CN02114A (OSRAM) | 2011-09-20 | 2015-05-29 | Sinai School Medicine | |
| CA2849471A1 (en) * | 2011-09-30 | 2013-04-04 | Novavax, Inc. | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
| CN104093422B (zh) * | 2012-01-24 | 2018-02-23 | 乔治亚大学研究基金公司 | 基于副流感病毒5的疫苗 |
| EP4154907A1 (en) | 2012-12-18 | 2023-03-29 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| BR112015019126A2 (pt) * | 2013-02-11 | 2017-08-22 | Novavax Inc | Vacina de combinação para vírus sincicial respiratório e influenza |
| WO2014159960A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
| JP2018504412A (ja) | 2015-01-23 | 2018-02-15 | アイカーン スクール オブ メディシン アット マウント サイナイ | インフルエンザウイルスワクチン接種レジメン |
| US10426829B2 (en) | 2015-09-03 | 2019-10-01 | Novavax, Inc. | Vaccine compositions having improved stability and immunogenicity |
| WO2017218624A1 (en) | 2016-06-15 | 2017-12-21 | Icahn School Of Medicine At Mount Sinai | Influenza virus hemagglutinin proteins and uses thereof |
| US11254733B2 (en) | 2017-04-07 | 2022-02-22 | Icahn School Of Medicine At Mount Sinai | Anti-influenza B virus neuraminidase antibodies and uses thereof |
| ES3028362T3 (en) | 2017-07-24 | 2025-06-19 | Novavax Inc | Methods and compositions for treating respiratory disease |
| CA3092984A1 (en) | 2018-03-19 | 2019-09-26 | Novavax, Inc. | Multivalent influenza nanoparticle vaccines |
| EP3810634A4 (en) | 2018-06-21 | 2022-07-27 | Icahn School of Medicine at Mount Sinai | Mosaic influenza virus hemagglutinin polypeptides and uses thereof |
| CN110237248A (zh) * | 2019-07-01 | 2019-09-17 | 大连民族大学 | 一种带状疱疹疫苗的制备方法 |
| JP2023530445A (ja) * | 2020-06-17 | 2023-07-18 | メイッサ ヴァクシーン，インコーポレイテッド | キメラｒｓｖおよびコロナウイルスタンパク質、免疫原性組成物、ならびに使用方法 |
| GB202017649D0 (en) * | 2020-11-09 | 2020-12-23 | Autolus Ltd | Polypeptide |
| KR102680105B1 (ko) * | 2021-05-17 | 2024-07-02 | 대한민국 | 코로나19 바이러스 및 인플루엔자 h1n1 바이러스에 대한 바이러스 유사입자 및 이의 용도 |
| KR20250143785A (ko) * | 2023-01-19 | 2025-10-02 | 시아먼 유니버시티 | 수두-대상포진 바이러스의 ge 및 gi 융합 단백질 및 이의 용도 |
| CN119080948B (zh) * | 2023-04-17 | 2025-05-27 | 北京康乐卫士生物技术股份有限公司 | 带状疱疹病毒疫苗的嵌合抗原及其应用 |
| WO2025103290A1 (zh) * | 2023-11-13 | 2025-05-22 | 石药集团巨石生物制药有限公司 | 一种抵抗带状疱疹的mRNA疫苗及其制备方法 |
| CN120020142A (zh) * | 2023-11-20 | 2025-05-20 | 上海蓝鹊生物医药有限公司 | 一种vzv抗原变体、核酸、药物组合物及其应用 |
| CN119684476B (zh) * | 2025-02-21 | 2025-05-06 | 中国医学科学院医学生物学研究所 | 一种抗水痘-带状疱疹病毒单克隆抗体及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| US6387373B1 (en) | 1993-01-15 | 2002-05-14 | Novavax, Inc. | Vaccines containing paucilsmellar lipid vesicles as immunological adjuvants |
| US5629021A (en) | 1995-01-31 | 1997-05-13 | Novavax, Inc. | Micellar nanoparticles |
| WO2003068163A2 (en) | 2002-02-14 | 2003-08-21 | Novavax, Inc. | Optimization of gene sequences of chimeric virus-like particles for expression in insect cells |
| US8592197B2 (en) * | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| MXPA04010902A (es) * | 2004-11-03 | 2006-05-08 | Alvaro Raul Lara Rodriguez | Vacuna recombinante a partir de las proteinas ge, gi y gb del virus de varicela zoster como tratamiento y prevencion de esclerosis multiple. |
| US7951384B2 (en) * | 2005-08-05 | 2011-05-31 | University Of Massachusetts | Virus-like particles as vaccines for paramyxovirus |
| BRPI0617486A2 (pt) * | 2005-10-18 | 2011-07-26 | Novavax Inc | vacina que compreende partÍculas similares a vÍrus da gripe funcionais (vlp) e uso de uma vlp de gripe |
-
2008
- 2008-07-21 WO PCT/US2008/070636 patent/WO2009012487A2/en not_active Ceased
- 2008-07-21 US US12/669,703 patent/US20110008838A1/en not_active Abandoned
- 2008-07-21 EP EP08782139A patent/EP2176427A4/en not_active Withdrawn
- 2008-07-21 ES ES12185712.2T patent/ES2542644T3/es active Active
- 2008-07-21 SI SI200831460T patent/SI2540312T1/sl unknown
- 2008-07-21 PL PL12185712T patent/PL2540312T3/pl unknown
- 2008-07-21 JP JP2010517201A patent/JP2010533737A/ja not_active Withdrawn
- 2008-07-21 HU HUE12185712A patent/HUE025702T2/en unknown
- 2008-07-21 WO PCT/US2008/070638 patent/WO2009012489A1/en not_active Ceased
- 2008-07-21 DK DK12185712.2T patent/DK2540312T3/en active
- 2008-07-21 PT PT121857122T patent/PT2540312E/pt unknown
- 2008-07-21 EP EP08796367A patent/EP2175883A4/en not_active Withdrawn
- 2008-07-21 EP EP20120185712 patent/EP2540312B1/en active Active
- 2008-07-21 CA CA 2693899 patent/CA2693899A1/en not_active Abandoned
- 2008-07-21 CN CN200880108050A patent/CN101801411A/zh active Pending
-
2015
- 2015-07-09 HR HRP20150758TT patent/HRP20150758T1/hr unknown
- 2015-07-14 CY CY20151100613T patent/CY1116583T1/el unknown
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