JP2010529167A - 神経変性疾患または血液疾患の治療のための[1,10]−フェナントロリン誘導体 - Google Patents

神経変性疾患または血液疾患の治療のための[1,10]−フェナントロリン誘導体 Download PDF

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JP2010529167A
JP2010529167A JP2010511627A JP2010511627A JP2010529167A JP 2010529167 A JP2010529167 A JP 2010529167A JP 2010511627 A JP2010511627 A JP 2010511627A JP 2010511627 A JP2010511627 A JP 2010511627A JP 2010529167 A JP2010529167 A JP 2010529167A
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phenanthroline
compound
carbaldehyde
alkyl
formula
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JP2010529167A5 (enExample
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アナ、マルティネス、ヒル
アナ、カストロ、モレラ
ミゲル、メディナ、パディリャ
ホルヘ、サンチェス‐ケサダ
メルセデス、アロンソ、カスコン
ラウラ、ルビオ、アリエタ
エスター、ガルシア、パロメロ
パオラ、ウサン、エゲア
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Noscira SA
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Noscira SA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
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  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2010511627A 2007-06-11 2008-06-11 神経変性疾患または血液疾患の治療のための[1,10]−フェナントロリン誘導体 Pending JP2010529167A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07380167A EP2002863A1 (en) 2007-06-11 2007-06-11 [1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases
PCT/EP2008/057319 WO2008152068A2 (en) 2007-06-11 2008-06-11 [1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases

Publications (2)

Publication Number Publication Date
JP2010529167A true JP2010529167A (ja) 2010-08-26
JP2010529167A5 JP2010529167A5 (enExample) 2014-01-30

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ID=38596362

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JP2010511627A Pending JP2010529167A (ja) 2007-06-11 2008-06-11 神経変性疾患または血液疾患の治療のための[1,10]−フェナントロリン誘導体

Country Status (13)

Country Link
US (2) US8592446B2 (enExample)
EP (2) EP2002863A1 (enExample)
JP (1) JP2010529167A (enExample)
CN (1) CN101801461A (enExample)
AR (1) AR066956A1 (enExample)
AU (1) AU2008263897A1 (enExample)
CA (1) CA2690455A1 (enExample)
CL (1) CL2008001719A1 (enExample)
MX (1) MX2009013482A (enExample)
RU (1) RU2009148821A (enExample)
TW (1) TW200914016A (enExample)
UY (1) UY31143A1 (enExample)
WO (1) WO2008152068A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024545840A (ja) * 2021-09-28 2024-12-13 ゼブラ デンマーク エー/エス オキシム類及びgba関連疾患の治療におけるそれらの使用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6000272B2 (ja) 2010-12-01 2016-09-28 中国石油化工股▲ふん▼有限公司 窒素のオルソ位にアシル基が置換した窒素含有複素環式化合物およびそのアミナール鉄(ii)錯体の製造方法
CN102532201B (zh) * 2010-12-01 2014-11-05 中国石油化工股份有限公司 甲酰基取代的1,10-菲咯啉配合物的制备及由此制备的配合物作为催化剂的应用
CN102558241B (zh) * 2010-12-01 2014-11-26 中国石油化工股份有限公司 丙酰基取代的1,10-菲咯啉配合物的制备及由此制备的配合物作为催化剂的应用
CN106083713B (zh) * 2016-07-15 2019-07-26 浙江工业大学 一种喹(喔)啉-2-甲醛类化合物的化学合成方法
WO2021176428A1 (en) * 2020-03-06 2021-09-10 Jawaharlal Nehru Centre For Advanced Scientific Research Phenanthroline, carbazole and flavylium based cyanines and compositions and methods of making and using the same
CN117983303B (zh) * 2022-11-01 2026-04-07 万华化学集团股份有限公司 一种金属配合物及其配体,催化剂组合物及香茅醇的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL76345B1 (enExample) * 1971-02-13 1975-06-30

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6013027849; MLOCHOWSKI, J. et al: 'Synthesis of phenanthroline analogs of cerulomycin' ROCZNIKI CHEMII Vol.45, No.5, 1971, p.803-9 *
JPN6013027852; GAETA, A. et al: 'The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy' BRITISH JOURNAL OF PHARMACOLOGY Vol.146, No.8, 2005, p.1041-1059 *
JPN7013002151; ポーランド国特許発明第76345号明細書 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024545840A (ja) * 2021-09-28 2024-12-13 ゼブラ デンマーク エー/エス オキシム類及びgba関連疾患の治療におけるそれらの使用

Also Published As

Publication number Publication date
CN101801461A (zh) 2010-08-11
WO2008152068A2 (en) 2008-12-18
CL2008001719A1 (es) 2009-01-02
MX2009013482A (es) 2010-01-27
US20140011835A1 (en) 2014-01-09
UY31143A1 (es) 2009-01-30
US20100240692A1 (en) 2010-09-23
CA2690455A1 (en) 2008-12-18
AU2008263897A1 (en) 2008-12-18
AR066956A1 (es) 2009-09-23
WO2008152068A3 (en) 2009-05-07
RU2009148821A (ru) 2011-07-20
EP2170464A2 (en) 2010-04-07
EP2002863A1 (en) 2008-12-17
TW200914016A (en) 2009-04-01
US8592446B2 (en) 2013-11-26

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