JP2010527621A5 - - Google Patents
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- JP2010527621A5 JP2010527621A5 JP2010509680A JP2010509680A JP2010527621A5 JP 2010527621 A5 JP2010527621 A5 JP 2010527621A5 JP 2010509680 A JP2010509680 A JP 2010509680A JP 2010509680 A JP2010509680 A JP 2010509680A JP 2010527621 A5 JP2010527621 A5 JP 2010527621A5
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| US20160279239A1 (en) * | 2011-05-02 | 2016-09-29 | Immunomedics, Inc. | Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease |
| US10155816B2 (en) * | 2005-11-28 | 2018-12-18 | Genmab A/S | Recombinant monovalent antibodies and methods for production thereof |
| WO2008145140A2 (en) | 2007-05-31 | 2008-12-04 | Genmab A/S | Transgenic animals producing monovalent human antibodies and antibodies obtainable from these animals |
| CA2745439C (en) * | 2008-12-03 | 2019-10-15 | Genmab A/S | Antibody variants having modifications in the constant region |
| EP2389392A1 (en) * | 2009-01-26 | 2011-11-30 | Genmab A/S | Methods for producing mixtures of antibodies |
| DE102009047243A1 (de) * | 2009-11-27 | 2011-06-01 | Orgentec Diagnostika Gmbh | Monospezifische Polypeptidreagenzien |
| WO2011110642A2 (en) | 2010-03-10 | 2011-09-15 | Genmab A/S | Monoclonal antibodies against c-met |
| WO2013003680A1 (en) | 2011-06-30 | 2013-01-03 | Genentech, Inc. | Anti-c-met antibody formulations |
| MX2014005885A (es) | 2011-11-21 | 2014-09-04 | Genentech Inc | Purificacion de anticuerpos anti-c-met. |
| TWI682941B (zh) | 2013-02-01 | 2020-01-21 | 美商再生元醫藥公司 | 含嵌合恆定區之抗體 |
| EP3107569A4 (en) | 2014-02-20 | 2018-02-21 | Alder Biopharmaceuticals, Inc. | Anti-acth antibodies and use thereof |
| TWI754319B (zh) | 2014-03-19 | 2022-02-01 | 美商再生元醫藥公司 | 用於腫瘤治療之方法及抗體組成物 |
| TWI668010B (zh) * | 2014-05-07 | 2019-08-11 | 丹麥商諾佛 儂迪克股份有限公司 | 使用ｇｌｐ－１及抗ｉｌ－２１治療糖尿病 |
| ES2809455T3 (es) | 2014-11-17 | 2021-03-04 | Regeneron Pharma | Métodos para tratamiento tumoral usando anticuerpo biespecífico CD3xCD20 |
| WO2016110576A1 (en) * | 2015-01-08 | 2016-07-14 | Genmab A/S | Bispecific antibodies against cd3 and cd20 |
| WO2016161010A2 (en) | 2015-03-30 | 2016-10-06 | Regeneron Pharmaceuticals, Inc. | Heavy chain constant regions with reduced binding to fc gamma receptors |
| KR102777500B1 (ko) | 2015-09-23 | 2025-03-11 | 리제너론 파아마슈티컬스, 인크. | 최적화된 항-cd3 이중특이적 항체 및 이의 용도 |
| CN114835795A (zh) * | 2015-11-16 | 2022-08-02 | Ubi蛋白公司 | 用于延长蛋白质半衰期的方法 |
| CN110352201A (zh) | 2017-04-03 | 2019-10-18 | 免疫医疗公司 | 用于癌症疗法的抗体药物缀合物的皮下施用 |
| TW202021618A (zh) | 2018-08-17 | 2020-06-16 | 美商２３與我有限公司 | 抗ｉｌ１ｒａｐ抗體及其使用方法 |
| PT3844189T (pt) | 2018-08-31 | 2025-01-29 | Regeneron Pharma | Estratégia de dosagem que mitiga a síndrome de libertação de citocinas para anticorpos bisepecíficos contra cd3/c20 |
| AR117327A1 (es) | 2018-12-20 | 2021-07-28 | 23Andme Inc | Anticuerpos anti-cd96 y métodos de uso de estos |
| US11884719B2 (en) | 2018-12-21 | 2024-01-30 | 23Andme, Inc. | Anti-IL-36 antibodies and methods of use thereof |
| BR112022022730A2 (pt) | 2020-05-08 | 2023-02-14 | Genmab As | Método para tratar um linfoma não hodgkin de células b em um indivíduo humano |
| WO2021243204A1 (en) | 2020-05-29 | 2021-12-02 | 23Andme, Inc. | Anti-cd200r1 antibodies and methods of use thereof |
| EP4168443A1 (en) | 2020-06-22 | 2023-04-26 | Almirall S.A. | Anti-il-36 antibodies and methods of use thereof |
| CA3192323A1 (en) | 2020-09-14 | 2022-03-17 | Julie MACOIN | Antibodies that bind to il1rap and uses thereof |
| WO2024123558A2 (en) * | 2022-12-05 | 2024-06-13 | The Scripps Research Institute | Engineered lassa viral immunogens and vaccine compositions |
| WO2024146458A1 (zh) * | 2023-01-06 | 2024-07-11 | 广东东阳光药业股份有限公司 | 抗il-11细胞因子人源化抗体 |
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| EP0307434B2 (en) * | 1987-03-18 | 1998-07-29 | Scotgen Biopharmaceuticals, Inc. | Altered antibodies |
| GB9206422D0 (en) * | 1992-03-24 | 1992-05-06 | Bolt Sarah L | Antibody preparation |
| AU2527397A (en) * | 1996-03-13 | 1997-10-01 | Protein Design Labs, Inc. | Fas ligand fusion proteins and their uses |
| US7754208B2 (en) * | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7829084B2 (en) * | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| WO2002070009A1 (en) * | 2001-02-27 | 2002-09-12 | Yasuda, Yoshiko | Preventives/remedies for thickened scar, keloid or chronic arthritic diseases |
| AU2002305478A1 (en) * | 2001-06-20 | 2003-01-08 | Molecular Staging, Inc. | Conjugates of reduced antibodies and biomolecules |
| GB2380127A (en) * | 2001-09-26 | 2003-04-02 | Isis Innovation | Treatment of chronic joint inflammation |
| US7053202B2 (en) * | 2001-10-19 | 2006-05-30 | Millennium Pharmaceuticals, Inc. | Immunoglobulin DNA cassette molecules, monobody constructs, methods of production, and methods of use therefor |
| US7317091B2 (en) * | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| WO2004029207A2 (en) * | 2002-09-27 | 2004-04-08 | Xencor Inc. | Optimized fc variants and methods for their generation |
| EP1578447A4 (en) * | 2002-10-31 | 2009-06-03 | Genentech Inc | METHOD AND COMPOSITIONS FOR INCREASING ANTIBODY PRODUCTION |
| AU2004309347B2 (en) * | 2003-12-19 | 2010-03-04 | Genentech, Inc. | Monovalent antibody fragments useful as therapeutics |
| CA2578613A1 (en) * | 2004-08-11 | 2007-01-25 | Trubion Pharmaceuticals, Inc. | Binding domain fusion proteins |
| TW200732350A (en) * | 2005-10-21 | 2007-09-01 | Amgen Inc | Methods for generating monovalent IgG |
| US10155816B2 (en) * | 2005-11-28 | 2018-12-18 | Genmab A/S | Recombinant monovalent antibodies and methods for production thereof |
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