JP2010527603A - 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異 - Google Patents

乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異 Download PDF

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JP2010527603A
JP2010527603A JP2010508970A JP2010508970A JP2010527603A JP 2010527603 A JP2010527603 A JP 2010527603A JP 2010508970 A JP2010508970 A JP 2010508970A JP 2010508970 A JP2010508970 A JP 2010508970A JP 2010527603 A JP2010527603 A JP 2010527603A
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breast cancer
allele
individual
risk
markers
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JP2010527603A5 (OSRAM
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サイモン ステイシー
パトリック スレム
アンドレイ マノレスク
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ディコーデ ジェネテクス イーエイチエフ
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10—Ploidy or copy number detection
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Wood Science & Technology (AREA)
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  • Molecular Biology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010508970A 2007-05-25 2008-05-21 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異 Pending JP2010527603A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IS8647 2007-05-25
IS8700 2007-12-21
PCT/IS2008/000012 WO2008146309A2 (en) 2007-05-25 2008-05-21 Genetic variants on chr 5pl2 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment

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JP2010527603A true JP2010527603A (ja) 2010-08-19
JP2010527603A5 JP2010527603A5 (OSRAM) 2011-07-07

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JP2010508970A Pending JP2010527603A (ja) 2007-05-25 2008-05-21 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのＣＨＲ５ｐ１２および１０ｑ２６上の遺伝的変異

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US (2) US8580501B2 (OSRAM)
EP (2) EP2164984A2 (OSRAM)
JP (1) JP2010527603A (OSRAM)
KR (1) KR20100017865A (OSRAM)
CN (1) CN101772578A (OSRAM)
AU (1) AU2008256219B2 (OSRAM)
CA (1) CA2688312A1 (OSRAM)
EA (1) EA018444B1 (OSRAM)
IL (1) IL202292A0 (OSRAM)
MX (1) MX2009012722A (OSRAM)
NZ (1) NZ581858A (OSRAM)
WO (1) WO2008146309A2 (OSRAM)

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US8951735B2 (en) 2008-07-07 2015-02-10 Decode Genetics Ehf. Genetic variants for breast cancer risk assessment
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JP6420543B2 (ja) * 2011-01-19 2018-11-07 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． ゲノムデータ処理方法
HK1197085A1 (en) * 2011-06-16 2015-01-02 Decode Genetics Ehf Genetic variants for predicting risk of breast cancer
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CN104232774A (zh) * 2014-09-17 2014-12-24 湖北维达健基因技术有限公司 用于检测乳腺癌易感基因snp的引物、荧光探针及应用
KR102334702B1 (ko) 2014-09-30 2021-12-06 지네틱 테크놀로지스 리미티드 유방암 발생 위험의 평가 방법
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CN106295241A (zh) * 2015-06-25 2017-01-04 杭州圣庭生物技术有限公司 基于brca1和brca2突变的乳腺癌患病风险评估算法
DK3325664T3 (da) 2015-07-23 2022-03-07 Univ Hong Kong Chinese Analyse af fragmenteringsmønstre for cellefrit DNA
CN105586427B (zh) * 2016-03-10 2020-06-19 厦门艾德生物医药科技股份有限公司 检测人类brca1和brca2基因突变的引物、试剂盒及方法
CN107723350A (zh) * 2016-08-12 2018-02-23 嘉兴允英医学检验有限公司 一种遗传性乳腺癌突变基因高通量筛查方法
ES2990117T3 (es) 2017-01-25 2024-11-28 Univ Hong Kong Chinese Aplicaciones de diagnóstico que utilizan fragmentos de ácido nucleico
ES2959360T3 (es) 2017-07-26 2024-02-23 Univ Hong Kong Chinese Mejora del cribado del cáncer mediante ácidos nucleicos víricos acelulares
CN107254546B (zh) * 2017-08-16 2020-11-03 复旦大学附属华山医院 一种与乳腺癌新辅助化疗疗效相关的snp标志物及其应用
CN107254545B (zh) * 2017-08-16 2020-09-15 复旦大学附属华山医院北院 一种与乳腺癌化疗毒性相关的snp标志物及其应用
CN107729241B (zh) * 2017-10-12 2020-11-03 中国矿业大学 一种基于变异体分组的软件变异测试数据进化生成方法
KR101985864B1 (ko) * 2017-12-28 2019-06-05 주식회사 엔젠바이오 유방암 및 난소암 등 암 진단용 조성물 및 이의 용도
CN109913550A (zh) * 2019-03-21 2019-06-21 吉林省银丰生物工程技术有限公司 乳腺癌新辅助化疗效果预测基因试剂盒
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CN110358834B (zh) * 2019-07-12 2023-05-16 深圳大学 一种lncRNA的应用以及试剂盒和药物
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US8580501B2 (en) 2013-11-12
KR20100017865A (ko) 2010-02-16
WO2008146309A3 (en) 2009-01-22
US20140179546A1 (en) 2014-06-26
EP2164984A2 (en) 2010-03-24
NZ581858A (en) 2012-07-27
US20110015081A1 (en) 2011-01-20
CA2688312A1 (en) 2008-12-04
EA018444B1 (ru) 2013-08-30
CN101772578A (zh) 2010-07-07
EA200971079A1 (ru) 2010-06-30
IL202292A0 (en) 2010-06-16
AU2008256219A1 (en) 2008-12-04
MX2009012722A (es) 2009-12-11
EP2535425A1 (en) 2012-12-19
AU2008256219B2 (en) 2014-06-05
WO2008146309A2 (en) 2008-12-04

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