JP2010525154A - Pva−paaヒドロゲル - Google Patents

Pva−paaヒドロゲル Download PDF

Info

Publication number
JP2010525154A
JP2010525154A JP2010506488A JP2010506488A JP2010525154A JP 2010525154 A JP2010525154 A JP 2010525154A JP 2010506488 A JP2010506488 A JP 2010506488A JP 2010506488 A JP2010506488 A JP 2010506488A JP 2010525154 A JP2010525154 A JP 2010525154A
Authority
JP
Japan
Prior art keywords
pva
paa
hydrogel
solution
peg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010506488A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010525154A5 (enExample
Inventor
チェ、ジェヤン
オルフン、ケイ.ムラトグル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of JP2010525154A publication Critical patent/JP2010525154A/ja
Publication of JP2010525154A5 publication Critical patent/JP2010525154A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/02Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075Macromolecular gels
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02Homopolymers or copolymers of unsaturated alcohols
    • C08L29/04Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2329/00Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Derivatives of such polymer
    • C08J2329/02Homopolymers or copolymers of unsaturated alcohols
    • C08J2329/04Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/02Homopolymers or copolymers of acids; Metal or ammonium salts thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2010506488A 2007-04-24 2008-04-24 Pva−paaヒドロゲル Pending JP2010525154A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91361807P 2007-04-24 2007-04-24
US96983107P 2007-09-04 2007-09-04
PCT/US2008/061388 WO2008131451A2 (en) 2007-04-24 2008-04-24 Pva-paa hydrogels

Publications (2)

Publication Number Publication Date
JP2010525154A true JP2010525154A (ja) 2010-07-22
JP2010525154A5 JP2010525154A5 (enExample) 2011-06-02

Family

ID=39876197

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010506488A Pending JP2010525154A (ja) 2007-04-24 2008-04-24 Pva−paaヒドロゲル

Country Status (6)

Country Link
US (2) US8541484B2 (enExample)
EP (1) EP2166991A4 (enExample)
JP (1) JP2010525154A (enExample)
AU (1) AU2008242534A1 (enExample)
CA (1) CA2685064A1 (enExample)
WO (1) WO2008131451A2 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018009096A (ja) * 2016-07-13 2018-01-18 地方独立行政法人東京都立産業技術研究センター ハイドロゲル及びハイドロゲルの製造方法
JP2019503767A (ja) * 2015-12-22 2019-02-14 アクセス・バスキュラー・インコーポレイテッドAccess Vascular, Inc. 高強度生体材
CN110997026A (zh) * 2017-06-21 2020-04-10 阿塞斯血管有限公司 并入有水溶性聚合物的高强度多孔材料
JP2022514368A (ja) * 2018-12-19 2022-02-10 アクセス・バスキュラー・インコーポレイテッド 放出制御用高強度多孔質材料
JP2022544190A (ja) * 2019-08-12 2022-10-17 ソルタム テクノロジーズ リミテッド 複合材料及びその使用
JP2022185763A (ja) * 2021-06-03 2022-12-15 朝日インテック株式会社 模擬血管

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010065951A1 (en) 2008-12-05 2010-06-10 Cambridge Polymer Group, Inc. Hydrolyzed hydrogels
CN101480501B (zh) * 2009-01-07 2012-10-24 四川大学 关节软骨修复的替代材料及制备方法
EP2473201B1 (en) * 2009-09-01 2016-08-10 Medovent GmbH Chitosan tissue dressing
GB201000879D0 (en) * 2010-01-20 2010-03-10 Univ Reading The Improved hydrogel synthesis
US20160144038A1 (en) * 2014-11-20 2016-05-26 Broda International, LLC Water-soluble supramolecular complexes
CN102639097A (zh) 2011-03-21 2012-08-15 博任达生化科技(上海)有限公司 逆向温敏可逆水凝胶组合物
ES2799179T3 (es) * 2014-03-06 2020-12-15 Airbus Defence & Space Gmbh Componente compuesto fibroso con cuerpo de relleno reticulado por radiación
US10022475B2 (en) * 2014-05-01 2018-07-17 Bao Tran Body augmentation device
EP3411422A1 (en) 2016-02-05 2018-12-12 The General Hospital Corporation Drug eluting polymer composed of biodegradable polymers applied to surface of medical device
US10510268B2 (en) * 2016-04-05 2019-12-17 Synaptive Medical (Barbados) Inc. Multi-metric surgery simulator and methods
CN106832073B (zh) * 2017-01-25 2019-03-05 东南大学 大分子链模板法制备聚丙烯酸类复合高分子水凝胶的方法
JP7076821B2 (ja) * 2017-06-02 2022-05-30 国立大学法人東北大学 生体組織の模型の乾燥体
WO2020163546A1 (en) 2019-02-06 2020-08-13 Monosol, Llc Water-soluble coatings for substrate surfaces
US12083246B2 (en) 2019-02-08 2024-09-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Composite gels and methods of use thereof
CN111058103B (zh) * 2019-12-26 2023-10-10 东华大学 一种交联大分子氢键复合物纤维的制备方法
EP4171704A4 (en) 2020-06-30 2024-10-23 Access Vascular, Inc. ARTICLES COMPRISING MARKINGS AND ASSOCIATED PROCESSES
CN113072712B (zh) * 2021-03-30 2022-01-18 国家地质实验测试中心 一种用于重金属离子吸附的改性共价有机框架材料及其制备方法与应用
CN113893386B (zh) * 2021-10-27 2022-06-03 四川大学华西医院 一种喷涂干粉凝胶敷料及其制备方法
CN114409930B (zh) * 2022-02-21 2023-08-01 青岛大学 一种具有类皮肤特性的凝胶材料及其制备方法和应用
CN114796620B (zh) * 2022-04-24 2023-09-29 广东顺德工业设计研究院(广东顺德创新设计研究院) 一种用作医用植入材料的互穿网络水凝胶及其制备方法和应用
CN114940726A (zh) * 2022-06-17 2022-08-26 重庆大学锂电及新材料遂宁研究院 一种水凝胶及其制备方法和应用
CN119174843B (zh) * 2024-09-20 2025-05-02 中山大学 一种超低溶胀率的梯度结构疝修复补片及其制备方法和应用
CN119264508B (zh) * 2024-09-20 2025-05-02 中山大学 一种梯度结构生物医用水凝胶的制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03161046A (ja) * 1989-11-20 1991-07-11 Terumo Corp 高含水高分子ブレンドヒドロゲルおよびその製造方法
JPH0438960A (ja) * 1990-06-04 1992-02-10 Yoichi Tatara ポリビニルアルコールとポリアクリル酸管人工血管
JPH05504689A (ja) * 1989-10-11 1993-07-22 メデイプロ・サイエンシーズ・リミテツド ヒドロゲル形成創傷包帯または皮膚コーテイング材料
JP2000204165A (ja) * 1999-01-12 2000-07-25 Sharp Corp 高分子ゲル複合体の製造方法
WO2006132661A1 (en) * 2005-06-06 2006-12-14 Massachusetts General Hospital Tough hydrogels

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4750482A (en) * 1982-02-25 1988-06-14 Pfizer Inc. Hydrophilic, elastomeric, pressure-sensitive adhesive
JPH0678460B2 (ja) 1985-05-01 1994-10-05 株式会社バイオマテリアル・ユニバース 多孔質透明ポリビニルアルユールゲル
US5522898A (en) 1993-09-16 1996-06-04 Howmedica Inc. Dehydration of hydrogels
US5540033A (en) 1994-01-10 1996-07-30 Cambrex Hydrogels Integrated Manufacturing process for hydrogels
US5705780A (en) 1995-06-02 1998-01-06 Howmedica Inc. Dehydration of hydrogels
DE69733879T2 (de) 1996-02-13 2006-02-09 The General Hospital Corp., Boston Bestrahlte und schmeltzbehandelte ultrahoch molekulare polyethylen prothesen
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5846214A (en) * 1996-03-29 1998-12-08 Nichiban Company Limited PVA hydrogel, hydrogel laminate using the same and hydrogel wound-dressing material using the same
US5981826A (en) 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
US6923831B2 (en) 1999-05-10 2005-08-02 Barry M. Fell Surgically implantable knee prosthesis having attachment apertures
US6866684B2 (en) 1999-05-10 2005-03-15 Barry M. Fell Surgically implantable knee prosthesis having different tibial and femoral surface profiles
US6855165B2 (en) 1999-05-10 2005-02-15 Barry M. Fell Surgically implantable knee prosthesis having enlarged femoral surface
US6911044B2 (en) 1999-05-10 2005-06-28 Barry M. Fell Surgically implantable knee prosthesis having medially shifted tibial surface
JP2005514496A (ja) 2002-01-04 2005-05-19 マサチューセッツ、ゼネラル、ホスピタル 溶融体を下回る温度で調製した残留フリーラジカルが減少した高弾性率架橋ポリエチレン
AU2003234159A1 (en) 2002-04-22 2003-11-03 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
US7485670B2 (en) 2002-08-02 2009-02-03 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
US7745532B2 (en) 2002-08-02 2010-06-29 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
PL1626799T3 (pl) 2003-04-30 2010-09-30 Univ Drexel Mieszaniny polimerów żelujące w podwyższonej temperaturze, do stosowania w materiałach biokompatybilnych
US7235592B2 (en) * 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
CA2607393A1 (en) 2005-05-18 2006-11-23 The General Hospital Corporation Dba Massachusetts General Hospital Hydrogels and hydrogel particles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05504689A (ja) * 1989-10-11 1993-07-22 メデイプロ・サイエンシーズ・リミテツド ヒドロゲル形成創傷包帯または皮膚コーテイング材料
JPH03161046A (ja) * 1989-11-20 1991-07-11 Terumo Corp 高含水高分子ブレンドヒドロゲルおよびその製造方法
JPH0438960A (ja) * 1990-06-04 1992-02-10 Yoichi Tatara ポリビニルアルコールとポリアクリル酸管人工血管
JP2000204165A (ja) * 1999-01-12 2000-07-25 Sharp Corp 高分子ゲル複合体の製造方法
WO2006132661A1 (en) * 2005-06-06 2006-12-14 Massachusetts General Hospital Tough hydrogels

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019503767A (ja) * 2015-12-22 2019-02-14 アクセス・バスキュラー・インコーポレイテッドAccess Vascular, Inc. 高強度生体材
JP7665280B2 (ja) 2015-12-22 2025-04-21 アクセス・バスキュラー・インコーポレイテッド 高強度生体材
JP2018009096A (ja) * 2016-07-13 2018-01-18 地方独立行政法人東京都立産業技術研究センター ハイドロゲル及びハイドロゲルの製造方法
CN110997026A (zh) * 2017-06-21 2020-04-10 阿塞斯血管有限公司 并入有水溶性聚合物的高强度多孔材料
JP2020525097A (ja) * 2017-06-21 2020-08-27 アクセス・バスキュラー・インコーポレイテッドAccess Vascular, Inc. 水溶性ポリマーを組み込んだ高強度ポーラス状材
JP2023093620A (ja) * 2017-06-21 2023-07-04 アクセス・バスキュラー・インコーポレイテッド 水溶性ポリマーを組み込んだ高強度ポーラス状材
JP2022514368A (ja) * 2018-12-19 2022-02-10 アクセス・バスキュラー・インコーポレイテッド 放出制御用高強度多孔質材料
JP2022544190A (ja) * 2019-08-12 2022-10-17 ソルタム テクノロジーズ リミテッド 複合材料及びその使用
JP7710645B2 (ja) 2019-08-12 2025-07-22 ソルタム テクノロジーズ リミテッド 複合材料及びその使用
JP2022185763A (ja) * 2021-06-03 2022-12-15 朝日インテック株式会社 模擬血管
JP7747448B2 (ja) 2021-06-03 2025-10-01 朝日インテック株式会社 模擬血管

Also Published As

Publication number Publication date
CA2685064A1 (en) 2008-10-30
US8541484B2 (en) 2013-09-24
EP2166991A4 (en) 2013-12-18
EP2166991A2 (en) 2010-03-31
WO2008131451A2 (en) 2008-10-30
WO2008131451A3 (en) 2008-12-18
US20100105801A1 (en) 2010-04-29
US20140058009A1 (en) 2014-02-27
AU2008242534A1 (en) 2008-10-30

Similar Documents

Publication Publication Date Title
JP2010525154A (ja) Pva−paaヒドロゲル
US10696802B2 (en) PVA hydrogels having improved creep resistance, lubricity, and toughness
US9394384B2 (en) Tough hydrogels
US10189961B2 (en) Creep resistant, highly lubricious, tough, and ionic hydrogels including PVA-PAAMPS hydrogels
US6231605B1 (en) Poly(vinyl alcohol) hydrogel
US20070299540A1 (en) Methods of making medical implants of poly (vinyl alcohol) hydrogel
AU2007267550A1 (en) Anti-cross-linking agents and methods for inhibiting cross-linking of injectable hydrogel formulations
EP1779877B1 (en) Bearing materials for medical implants
US20050065307A1 (en) Medical implant or medical implant part comprising porous UHMWPE and process for producing the same
US20150045909A1 (en) Highly porous polyvinyl hydrogels for cartilage resurfacing
JP2007167655A (ja) 繊維強化された水膨潤性物品に関する応用
EP1994948A2 (en) Method for producing hydrogel composition comprising crosslinked polyethylene oxide
US8084513B2 (en) Implant filling material and method
US20060241754A1 (en) Implant filling material and method
AU2012216443A1 (en) Anti-cross-linking agents and methods for inhibiting cross-linking of injectable hy-drogel formulations

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110414

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110414

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20121121

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121214

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130313

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130321

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130412

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130419

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20130716