CA2685064A1 - Pva-paa hydrogels - Google Patents

Pva-paa hydrogels Download PDF

Info

Publication number
CA2685064A1
CA2685064A1 CA002685064A CA2685064A CA2685064A1 CA 2685064 A1 CA2685064 A1 CA 2685064A1 CA 002685064 A CA002685064 A CA 002685064A CA 2685064 A CA2685064 A CA 2685064A CA 2685064 A1 CA2685064 A1 CA 2685064A1
Authority
CA
Canada
Prior art keywords
pva
paa
hydrogel
peg
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002685064A
Other languages
English (en)
French (fr)
Inventor
Jeeyoung Choi
Orhun K. Muratoglu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2685064A1 publication Critical patent/CA2685064A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02—Homopolymers or copolymers of unsaturated alcohols
    • C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2329/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Derivatives of such polymer
    • C08J2329/02—Homopolymers or copolymers of unsaturated alcohols
    • C08J2329/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/02—Homopolymers or copolymers of acids; Metal or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002685064A 2007-04-24 2008-04-24 Pva-paa hydrogels Abandoned CA2685064A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US91361807P 2007-04-24 2007-04-24
US60/913,618 2007-04-24
US96983107P 2007-09-04 2007-09-04
US60/969,831 2007-09-04
PCT/US2008/061388 WO2008131451A2 (en) 2007-04-24 2008-04-24 Pva-paa hydrogels

Publications (1)

Publication Number Publication Date
CA2685064A1 true CA2685064A1 (en) 2008-10-30

Family

ID=39876197

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002685064A Abandoned CA2685064A1 (en) 2007-04-24 2008-04-24 Pva-paa hydrogels

Country Status (6)

Country Link
US (2) US8541484B2 (enExample)
EP (1) EP2166991A4 (enExample)
JP (1) JP2010525154A (enExample)
AU (1) AU2008242534A1 (enExample)
CA (1) CA2685064A1 (enExample)
WO (1) WO2008131451A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010065951A1 (en) 2008-12-05 2010-06-10 Cambridge Polymer Group, Inc. Hydrolyzed hydrogels
CN101480501B (zh) * 2009-01-07 2012-10-24 四川大学 关节软骨修复的替代材料及制备方法
EP2473201B1 (en) * 2009-09-01 2016-08-10 Medovent GmbH Chitosan tissue dressing
GB201000879D0 (en) * 2010-01-20 2010-03-10 Univ Reading The Improved hydrogel synthesis
US20160144038A1 (en) * 2014-11-20 2016-05-26 Broda International, LLC Water-soluble supramolecular complexes
CN102639097A (zh) 2011-03-21 2012-08-15 博任达生化科技（上海）有限公司 逆向温敏可逆水凝胶组合物
ES2799179T3 (es) * 2014-03-06 2020-12-15 Airbus Defence & Space Gmbh Componente compuesto fibroso con cuerpo de relleno reticulado por radiación
US10022475B2 (en) * 2014-05-01 2018-07-17 Bao Tran Body augmentation device
AU2016377694A1 (en) 2015-12-22 2018-07-12 Access Vascular, Inc. High strength biomedical materials
EP3411422A1 (en) 2016-02-05 2018-12-12 The General Hospital Corporation Drug eluting polymer composed of biodegradable polymers applied to surface of medical device
US10510268B2 (en) * 2016-04-05 2019-12-17 Synaptive Medical (Barbados) Inc. Multi-metric surgery simulator and methods
JP6795344B2 (ja) * 2016-07-13 2020-12-02 地方独立行政法人東京都立産業技術研究センター ハイドロゲル及びハイドロゲルの製造方法
CN106832073B (zh) * 2017-01-25 2019-03-05 东南大学 大分子链模板法制备聚丙烯酸类复合高分子水凝胶的方法
JP7076821B2 (ja) * 2017-06-02 2022-05-30 国立大学法人東北大学 生体組織の模型の乾燥体
CA3067850A1 (en) * 2017-06-21 2018-12-27 Access Vascular, Inc High strength porous materials incorporating water soluble polymers
US12194198B2 (en) 2018-12-19 2025-01-14 Access Vascular, Inc. High strength porous materials for controlled release
WO2020163546A1 (en) 2019-02-06 2020-08-13 Monosol, Llc Water-soluble coatings for substrate surfaces
US12083246B2 (en) 2019-02-08 2024-09-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Composite gels and methods of use thereof
CA3149657A1 (en) * 2019-08-12 2021-02-18 Solutum Technologies Ltd Composites and uses thereof
CN111058103B (zh) * 2019-12-26 2023-10-10 东华大学 一种交联大分子氢键复合物纤维的制备方法
EP4171704A4 (en) 2020-06-30 2024-10-23 Access Vascular, Inc. ARTICLES COMPRISING MARKINGS AND ASSOCIATED PROCESSES
CN113072712B (zh) * 2021-03-30 2022-01-18 国家地质实验测试中心 一种用于重金属离子吸附的改性共价有机框架材料及其制备方法与应用
JP7747448B2 (ja) * 2021-06-03 2025-10-01 朝日インテック株式会社 模擬血管
CN113893386B (zh) * 2021-10-27 2022-06-03 四川大学华西医院 一种喷涂干粉凝胶敷料及其制备方法
CN114409930B (zh) * 2022-02-21 2023-08-01 青岛大学 一种具有类皮肤特性的凝胶材料及其制备方法和应用
CN114796620B (zh) * 2022-04-24 2023-09-29 广东顺德工业设计研究院(广东顺德创新设计研究院) 一种用作医用植入材料的互穿网络水凝胶及其制备方法和应用
CN114940726A (zh) * 2022-06-17 2022-08-26 重庆大学锂电及新材料遂宁研究院 一种水凝胶及其制备方法和应用
CN119174843B (zh) * 2024-09-20 2025-05-02 中山大学 一种超低溶胀率的梯度结构疝修复补片及其制备方法和应用
CN119264508B (zh) * 2024-09-20 2025-05-02 中山大学 一种梯度结构生物医用水凝胶的制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4750482A (en) * 1982-02-25 1988-06-14 Pfizer Inc. Hydrophilic, elastomeric, pressure-sensitive adhesive
JPH0678460B2 (ja) 1985-05-01 1994-10-05 株式会社バイオマテリアル・ユニバース 多孔質透明ポリビニルアルユールゲル
US4920158A (en) 1989-10-11 1990-04-24 Medipro Sciences Limited Hydrogel-forming wound dressing or skin coating material
JPH03161046A (ja) * 1989-11-20 1991-07-11 Terumo Corp 高含水高分子ブレンドヒドロゲルおよびその製造方法
JPH0438960A (ja) * 1990-06-04 1992-02-10 Yoichi Tatara ポリビニルアルコールとポリアクリル酸管人工血管
US5522898A (en) 1993-09-16 1996-06-04 Howmedica Inc. Dehydration of hydrogels
US5540033A (en) 1994-01-10 1996-07-30 Cambrex Hydrogels Integrated Manufacturing process for hydrogels
US5705780A (en) 1995-06-02 1998-01-06 Howmedica Inc. Dehydration of hydrogels
DE69733879T2 (de) 1996-02-13 2006-02-09 The General Hospital Corp., Boston Bestrahlte und schmeltzbehandelte ultrahoch molekulare polyethylen prothesen
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5846214A (en) * 1996-03-29 1998-12-08 Nichiban Company Limited PVA hydrogel, hydrogel laminate using the same and hydrogel wound-dressing material using the same
US5981826A (en) 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
JP2000204165A (ja) 1999-01-12 2000-07-25 Sharp Corp 高分子ゲル複合体の製造方法
US6923831B2 (en) 1999-05-10 2005-08-02 Barry M. Fell Surgically implantable knee prosthesis having attachment apertures
US6866684B2 (en) 1999-05-10 2005-03-15 Barry M. Fell Surgically implantable knee prosthesis having different tibial and femoral surface profiles
US6855165B2 (en) 1999-05-10 2005-02-15 Barry M. Fell Surgically implantable knee prosthesis having enlarged femoral surface
US6911044B2 (en) 1999-05-10 2005-06-28 Barry M. Fell Surgically implantable knee prosthesis having medially shifted tibial surface
JP2005514496A (ja) 2002-01-04 2005-05-19 マサチューセッツ、ゼネラル、ホスピタル 溶融体を下回る温度で調製した残留フリーラジカルが減少した高弾性率架橋ポリエチレン
AU2003234159A1 (en) 2002-04-22 2003-11-03 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
US7485670B2 (en) 2002-08-02 2009-02-03 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
US7745532B2 (en) 2002-08-02 2010-06-29 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
PL1626799T3 (pl) 2003-04-30 2010-09-30 Univ Drexel Mieszaniny polimerów żelujące w podwyższonej temperaturze, do stosowania w materiałach biokompatybilnych
US7235592B2 (en) * 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
CA2607393A1 (en) 2005-05-18 2006-11-23 The General Hospital Corporation Dba Massachusetts General Hospital Hydrogels and hydrogel particles
AU2005332651A1 (en) * 2005-06-06 2006-12-14 Massachusetts General Hospital Tough hydrogels

Also Published As

Publication number Publication date
US8541484B2 (en) 2013-09-24
EP2166991A4 (en) 2013-12-18
EP2166991A2 (en) 2010-03-31
JP2010525154A (ja) 2010-07-22
WO2008131451A2 (en) 2008-10-30
WO2008131451A3 (en) 2008-12-18
US20100105801A1 (en) 2010-04-29
US20140058009A1 (en) 2014-02-27
AU2008242534A1 (en) 2008-10-30

Similar Documents

Publication Publication Date Title
US8541484B2 (en) PVA-PAA hydrogels
US10696802B2 (en) PVA hydrogels having improved creep resistance, lubricity, and toughness
US10189961B2 (en) Creep resistant, highly lubricious, tough, and ionic hydrogels including PVA-PAAMPS hydrogels
US9394384B2 (en) Tough hydrogels
CA2554777C (en) Highly crystalline cross-linked oxidation-resistant polyethylene
US20090054545A1 (en) Anti-cross-linking agents and methods for inhibiting cross-linking of injectable hydrogel formulations
AU2004216616B2 (en) Medical implant or medical implant part and method for producing the same
AU2008207807B2 (en) Methods for making oxidation-resistant cross-linked polymeric materials
US20150045909A1 (en) Highly porous polyvinyl hydrogels for cartilage resurfacing
JP2002519156A (ja) 修復および形成手術において特に有用な二相性注射用組成物
WO2013006237A1 (en) Injectable cross-linked hydrogels for biomaterial applications
EP1642595B1 (en) Method for producing hydrogel composition comprising crosslinked polyethylene oxide
KR20180010565A (ko) 모듈러스가 향상된 하이드로젤 및 이의 의료 용도

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140424