JP2010523571A5 - - Google Patents

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Publication number
JP2010523571A5
JP2010523571A5 JP2010502149A JP2010502149A JP2010523571A5 JP 2010523571 A5 JP2010523571 A5 JP 2010523571A5 JP 2010502149 A JP2010502149 A JP 2010502149A JP 2010502149 A JP2010502149 A JP 2010502149A JP 2010523571 A5 JP2010523571 A5 JP 2010523571A5
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JP
Japan
Prior art keywords
composition
item
tris
lyophilizate
crystalline compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010502149A
Other languages
English (en)
Japanese (ja)
Other versions
JP5659010B2 (ja
JP2010523571A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/004449 external-priority patent/WO2008124097A2/en
Publication of JP2010523571A publication Critical patent/JP2010523571A/ja
Publication of JP2010523571A5 publication Critical patent/JP2010523571A5/ja
Application granted granted Critical
Publication of JP5659010B2 publication Critical patent/JP5659010B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010502149A 2007-04-06 2008-04-04 イソホスホルアミドマスタードの塩およびそれらの類似体 Expired - Fee Related JP5659010B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US92214807P 2007-04-06 2007-04-06
US60/922,148 2007-04-06
US92736307P 2007-05-02 2007-05-02
US60/927,363 2007-05-02
US93491407P 2007-06-15 2007-06-15
US60/934,914 2007-06-15
US123707P 2007-10-30 2007-10-30
US61/001,237 2007-10-30
PCT/US2008/004449 WO2008124097A2 (en) 2007-04-06 2008-04-04 Salts of isophosphoramide mustard and analogs thereof

Publications (3)

Publication Number Publication Date
JP2010523571A JP2010523571A (ja) 2010-07-15
JP2010523571A5 true JP2010523571A5 (https=) 2012-05-31
JP5659010B2 JP5659010B2 (ja) 2015-01-28

Family

ID=39387443

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010502149A Expired - Fee Related JP5659010B2 (ja) 2007-04-06 2008-04-04 イソホスホルアミドマスタードの塩およびそれらの類似体

Country Status (22)

Country Link
US (2) US8604007B2 (https=)
EP (2) EP2581367B1 (https=)
JP (1) JP5659010B2 (https=)
KR (3) KR101505415B1 (https=)
CN (2) CN102942589B (https=)
AU (1) AU2008236684B2 (https=)
BR (1) BRPI0809999A2 (https=)
CA (1) CA2684747A1 (https=)
CY (1) CY1116596T1 (https=)
DK (2) DK2155682T3 (https=)
ES (1) ES2547302T3 (https=)
HU (1) HUE025949T2 (https=)
IL (2) IL201424A (https=)
MX (1) MX2009010820A (https=)
NZ (1) NZ580341A (https=)
PL (1) PL2155682T3 (https=)
PT (2) PT2581367E (https=)
RU (1) RU2527531C2 (https=)
SI (1) SI2155682T1 (https=)
TW (2) TWI490226B (https=)
WO (1) WO2008124097A2 (https=)
ZA (1) ZA200907722B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2565929T3 (es) * 2004-10-25 2016-04-07 Dekk-Tec, Inc. Sales de mostaza de isofosforamida y análogos de las mismas como agentes antitumorales
US7964583B2 (en) * 2006-02-17 2011-06-21 Ziopharm Oncology, Inc. Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents
ES2547302T3 (es) 2007-04-06 2015-10-05 Ziopharm Oncology, Inc. Sales de mostaza de isofosforamida y análogos de las mismas
CA2732290A1 (en) * 2008-07-31 2010-02-04 Ziopharm Oncology, Inc. Synthesis and formulations of salts of isophosphoramide mustard and analogs thereof
JP5779106B2 (ja) * 2009-02-24 2015-09-16 デック−テック, インコーポレイテッド 抗腫瘍剤としての4−ヒドロペルオキシイホスファミドの錯体
US20130196000A1 (en) * 2012-01-31 2013-08-01 Ziopharm Oncology, Inc. Combination therapy including isophosphoramide mustard, analogs, or salts thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU427945A1 (ru) 1972-07-24 1974-05-15 Институт элементоорганических соединений СПОСОБ ПОЛУЧЕНИЯа ПОЛИФТОРАЛКИЛЗАМЕЩЕННЫХБЕНЗИЛДИХЛОРФОСФАТОВ
JPS5159886A (https=) 1974-11-20 1976-05-25 Shionogi Seiyaku Kk
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide
US5091552A (en) 1986-06-30 1992-02-25 Board Of Regents, The University Of Texas System Novel antitumor aldophosphamide analogs
US5055459A (en) * 1986-06-30 1991-10-08 Board Of Regents, The University Of Texas Selective elimination of malignant cells from bone marrow by bis (acyloxy) propylphosphoramidates
US5204335A (en) * 1986-10-31 1993-04-20 Asta Pharma Aktiengesellschaft Ifosfamide lyophilisate and process for its preparation
JPH07505887A (ja) 1992-04-17 1995-06-29 アボツト・ラボラトリーズ タキソール誘導体
US5468499A (en) * 1993-11-15 1995-11-21 Ohio State University Liposomes containing the salt of phosphoramide mustard and related compounds
US5659061A (en) * 1995-04-20 1997-08-19 Drug Innovation & Design, Inc. Tumor protease activated prodrugs of phosphoramide mustard analogs with toxification and detoxification functionalities
DK0795334T3 (da) * 1996-03-12 2006-06-06 Sanofi Aventis Deutschland Nye prodrugs til behandling af tumorer og betændelsessygdomme
US5912264A (en) 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
EP1185276B1 (en) 1999-05-24 2003-12-10 Southern Research Institute Isophosphoramide mustard analogs and use thereof
CO5280224A1 (es) 2000-02-02 2003-05-30 Univ Florida State Res Found Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
WO2001079158A2 (en) 2000-04-13 2001-10-25 Hsc Research And Development Limited Partnership Compounds for modulating cell proliferation
DE60330407D1 (de) 2002-08-23 2010-01-14 Sloan Kettering Inst Cancer Synthese von Epothilonen, Zwischenprodukte davon, Analoga und ihre Verwendung
ES2565929T3 (es) * 2004-10-25 2016-04-07 Dekk-Tec, Inc. Sales de mostaza de isofosforamida y análogos de las mismas como agentes antitumorales
ES2547302T3 (es) 2007-04-06 2015-10-05 Ziopharm Oncology, Inc. Sales de mostaza de isofosforamida y análogos de las mismas

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