JP2010522699A5 - - Google Patents
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- Publication number
- JP2010522699A5 JP2010522699A5 JP2010500039A JP2010500039A JP2010522699A5 JP 2010522699 A5 JP2010522699 A5 JP 2010522699A5 JP 2010500039 A JP2010500039 A JP 2010500039A JP 2010500039 A JP2010500039 A JP 2010500039A JP 2010522699 A5 JP2010522699 A5 JP 2010522699A5
- Authority
- JP
- Japan
- Prior art keywords
- scoliosis
- opn
- subject
- expression
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004264 Osteopontin Human genes 0.000 claims 35
- 108010081689 Osteopontin Proteins 0.000 claims 35
- 238000000034 method Methods 0.000 claims 34
- 206010039722 scoliosis Diseases 0.000 claims 28
- 239000000523 sample Substances 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 12
- 230000002265 prevention Effects 0.000 claims 9
- 238000002965 ELISA Methods 0.000 claims 4
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 4
- 102100032912 CD44 antigen Human genes 0.000 claims 3
- 208000022567 adolescent idiopathic scoliosis Diseases 0.000 claims 3
- 239000013060 biological fluid Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000005259 measurement Methods 0.000 claims 3
- 229940122231 Osteopontin inhibitor Drugs 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 238000003127 radioimmunoassay Methods 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000001964 muscle biopsy Methods 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 229910052711 selenium Inorganic materials 0.000 claims 1
- 239000011669 selenium Substances 0.000 claims 1
- 210000001138 tear Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90940807P | 2007-03-30 | 2007-03-30 | |
| US60/909,408 | 2007-03-30 | ||
| US2557108P | 2008-02-01 | 2008-02-01 | |
| US61/025,571 | 2008-02-01 | ||
| PCT/CA2008/000595 WO2008119170A1 (en) | 2007-03-30 | 2008-03-31 | Method of determining risk of scoliosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010522699A JP2010522699A (ja) | 2010-07-08 |
| JP2010522699A5 true JP2010522699A5 (enExample) | 2011-04-28 |
| JP5426530B2 JP5426530B2 (ja) | 2014-02-26 |
Family
ID=39807753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500039A Expired - Fee Related JP5426530B2 (ja) | 2007-03-30 | 2008-03-31 | 脊柱側弯症の危険性の決定方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20100075333A1 (enExample) |
| EP (1) | EP2132568B1 (enExample) |
| JP (1) | JP5426530B2 (enExample) |
| KR (1) | KR101436578B1 (enExample) |
| CN (1) | CN101680887B (enExample) |
| AU (1) | AU2008234374B2 (enExample) |
| CA (1) | CA2682114C (enExample) |
| IL (1) | IL201186A (enExample) |
| MX (1) | MX2009010400A (enExample) |
| WO (1) | WO2008119170A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2616808T3 (es) * | 2010-10-04 | 2017-06-14 | Chu Sainte-Justine | Métodos de base biomecánica de diagnóstico de escoliosis |
| DE102012102338A1 (de) | 2012-03-20 | 2013-09-26 | Hauni Maschinenbau Ag | Messanordnung zum Messen von in Strangmaschinen der Tabak verarbeitenden Industrie hergestellten und geförderten Strängen |
| PT2882441T (pt) | 2012-08-09 | 2020-06-29 | Celgene Corp | Tratamento de doenças associadas à imunidade e inflamatórias |
| US20150038511A1 (en) | 2012-08-09 | 2015-02-05 | Celgene Corporation | Treatment of immune-related and inflammatory diseases |
| KR20160020552A (ko) | 2013-06-17 | 2016-02-23 | 슈 생-쥐스땡 | 척추측만증 및 척추측만증 진행에 대한 마커로서 Gi 단백질 인산화, 척추측만 개체에서 GiPCR 신호전달을 증가시키는 방법 |
| EP3010541B1 (en) * | 2013-06-17 | 2019-04-10 | Chu Sainte-Justine | A method of diagnosing a scoliotic subject |
| EP3011332B1 (en) * | 2013-06-17 | 2019-09-18 | CHU Sainte-Justine | New markers for severe progression of idiopathic scoliosis and uses thereof to stratify scoliotic patients and predict the risk of developing scoliosis |
| WO2015032004A1 (en) | 2013-09-09 | 2015-03-12 | Chu Sainte-Justine | Method of treating and prognosing scoliotic patient subgroups |
| ES2969532T3 (es) | 2014-05-19 | 2024-05-21 | Celgene Corp | 3-(4-((4-(Morfolinometil-bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona para el tratamiento de lupus eritematoso sistémico |
| CN106310610A (zh) * | 2016-10-21 | 2017-01-11 | 上海交通大学医学院附属新华医院 | 一种脊柱侧凸特定运动疗法 |
| CN106841593B (zh) * | 2017-03-24 | 2018-08-17 | 北京致成生物医学科技有限公司 | Lacc1和fhl2基因在制备脊柱侧弯检测产品中的应用 |
| CN111638329B (zh) * | 2020-06-09 | 2021-06-01 | 南方医科大学 | 一种用于检测布鲁氏菌病elispot检测试剂盒及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| SE9101642D0 (sv) * | 1991-05-30 | 1991-05-30 | Kabi Pharmacia Ab | Phospholipids |
| EP0705436A1 (de) * | 1993-06-22 | 1996-04-10 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur diagnose und analyse von mammakarzinomen |
| IL114914A0 (en) | 1994-08-30 | 1995-12-08 | Hyal Pharma Corp | Modulation of cellular activity |
| US5858709A (en) * | 1996-10-15 | 1999-01-12 | Smithkline Beecham P.L.C. | Fibronectin binding protein B compounds |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US20020160970A1 (en) * | 1996-04-10 | 2002-10-31 | Gyula Hadlaczky | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| WO1998008379A1 (en) | 1996-08-27 | 1998-03-05 | Dana-Farber Cancer Institute | Methods for identifying modulators of cellular interactions mediated by osteopontin |
| US6150162A (en) * | 1998-12-17 | 2000-11-21 | Isis Pharmaceuticals Inc. | Antisense modulation of CD44 expression |
| AU3149200A (en) | 1999-01-18 | 2000-08-01 | Osteometer Biotech As | Genetic predisposition |
| IL145851A0 (en) * | 1999-04-15 | 2002-07-25 | Childrens Medical Center | Osteopontin-derived chemotactic and inhivitory agents and uses therefor |
| JP2003528322A (ja) | 2000-03-23 | 2003-09-24 | グラクソ グループ リミテッド | オステオポンチンのインヒビターのスクリーニング方法 |
| RU2305111C2 (ru) * | 2001-09-25 | 2007-08-27 | Джуридикэл Фаундейшн Дзе Чемо-Серо-Терапьютик Рисерч Инститьют | Рекомбинантное антитело против остеопонтина и его применение |
| CA2373854A1 (en) * | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
| EP1532268A4 (en) * | 2002-03-21 | 2006-07-05 | Yissum Res Dev Co | PERIPHERAL BLOOD CELL MARKERS SUITABLE FOR THE DIAGNOSIS OF MULTIPLE SCLEROSIS AND THESE USEFUL METHODS AND KITS |
| US20040110933A1 (en) * | 2002-09-13 | 2004-06-10 | Dyax Corporation | CD44-binding ligands |
| US20050282163A1 (en) * | 2003-02-03 | 2005-12-22 | Medstar Research Institute Washington Hospital Center | Polymorphisms in elastin, fibrillin and related genes as predisposing to restenosis and to a therosclerosis |
| US20090104620A1 (en) * | 2007-07-03 | 2009-04-23 | Axial Biotech, Inc. | Simplified Method of Determining Predisposition to Scoliosis |
-
2008
- 2008-03-31 US US12/594,181 patent/US20100075333A1/en not_active Abandoned
- 2008-03-31 CA CA2682114A patent/CA2682114C/en not_active Expired - Fee Related
- 2008-03-31 KR KR1020097022732A patent/KR101436578B1/ko not_active Expired - Fee Related
- 2008-03-31 CN CN200880017111.6A patent/CN101680887B/zh not_active Expired - Fee Related
- 2008-03-31 AU AU2008234374A patent/AU2008234374B2/en not_active Ceased
- 2008-03-31 MX MX2009010400A patent/MX2009010400A/es active IP Right Grant
- 2008-03-31 EP EP08733693.9A patent/EP2132568B1/en not_active Not-in-force
- 2008-03-31 JP JP2010500039A patent/JP5426530B2/ja not_active Expired - Fee Related
- 2008-03-31 WO PCT/CA2008/000595 patent/WO2008119170A1/en not_active Ceased
-
2009
- 2009-09-24 IL IL201186A patent/IL201186A/en active IP Right Grant
-
2013
- 2013-02-22 US US13/775,069 patent/US20130266966A1/en not_active Abandoned
-
2015
- 2015-07-23 US US14/807,450 patent/US10073101B2/en active Active
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