JP2010522699A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010522699A5 JP2010522699A5 JP2010500039A JP2010500039A JP2010522699A5 JP 2010522699 A5 JP2010522699 A5 JP 2010522699A5 JP 2010500039 A JP2010500039 A JP 2010500039A JP 2010500039 A JP2010500039 A JP 2010500039A JP 2010522699 A5 JP2010522699 A5 JP 2010522699A5
- Authority
- JP
- Japan
- Prior art keywords
- scoliosis
- opn
- subject
- expression
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004264 Osteopontin Human genes 0.000 claims 35
- 108010081689 Osteopontin Proteins 0.000 claims 35
- 238000000034 method Methods 0.000 claims 34
- 206010039722 scoliosis Diseases 0.000 claims 28
- 239000000523 sample Substances 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 12
- 230000002265 prevention Effects 0.000 claims 9
- 238000002965 ELISA Methods 0.000 claims 4
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 4
- 102100032912 CD44 antigen Human genes 0.000 claims 3
- 208000022567 adolescent idiopathic scoliosis Diseases 0.000 claims 3
- 239000013060 biological fluid Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000005259 measurement Methods 0.000 claims 3
- 229940122231 Osteopontin inhibitor Drugs 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 238000003127 radioimmunoassay Methods 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000001964 muscle biopsy Methods 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 229910052711 selenium Inorganic materials 0.000 claims 1
- 239000011669 selenium Substances 0.000 claims 1
- 210000001138 tear Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90940807P | 2007-03-30 | 2007-03-30 | |
| US60/909,408 | 2007-03-30 | ||
| US2557108P | 2008-02-01 | 2008-02-01 | |
| US61/025,571 | 2008-02-01 | ||
| PCT/CA2008/000595 WO2008119170A1 (en) | 2007-03-30 | 2008-03-31 | Method of determining risk of scoliosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010522699A JP2010522699A (ja) | 2010-07-08 |
| JP2010522699A5 true JP2010522699A5 (enExample) | 2011-04-28 |
| JP5426530B2 JP5426530B2 (ja) | 2014-02-26 |
Family
ID=39807753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500039A Expired - Fee Related JP5426530B2 (ja) | 2007-03-30 | 2008-03-31 | 脊柱側弯症の危険性の決定方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20100075333A1 (enExample) |
| EP (1) | EP2132568B1 (enExample) |
| JP (1) | JP5426530B2 (enExample) |
| KR (1) | KR101436578B1 (enExample) |
| CN (1) | CN101680887B (enExample) |
| AU (1) | AU2008234374B2 (enExample) |
| CA (1) | CA2682114C (enExample) |
| IL (1) | IL201186A (enExample) |
| MX (1) | MX2009010400A (enExample) |
| WO (1) | WO2008119170A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012045176A1 (en) * | 2010-10-04 | 2012-04-12 | Chu Sainte-Justine | Biomechanical-based methods of diagnosing scoliosis |
| DE102012102338A1 (de) | 2012-03-20 | 2013-09-26 | Hauni Maschinenbau Ag | Messanordnung zum Messen von in Strangmaschinen der Tabak verarbeitenden Industrie hergestellten und geförderten Strängen |
| US20150038511A1 (en) | 2012-08-09 | 2015-02-05 | Celgene Corporation | Treatment of immune-related and inflammatory diseases |
| AU2013299625B2 (en) | 2012-08-09 | 2018-02-01 | Celgene Corporation | Treatment of immune-related and inflammatory diseases |
| CA2914213A1 (en) | 2013-06-17 | 2014-12-24 | Alain Moreau | A method of increasing gipcr signalization in the cells of a scoliotic subject |
| CN105408744B (zh) * | 2013-06-17 | 2019-05-21 | 圣-贾斯汀大学中心医院 | 特发性脊柱侧凸的严重进展的新标记物及其用于分层脊柱侧凸患者和预测发展脊柱侧凸的风险的用途 |
| KR20160020552A (ko) | 2013-06-17 | 2016-02-23 | 슈 생-쥐스땡 | 척추측만증 및 척추측만증 진행에 대한 마커로서 Gi 단백질 인산화, 척추측만 개체에서 GiPCR 신호전달을 증가시키는 방법 |
| WO2015032005A1 (en) * | 2013-09-09 | 2015-03-12 | Chu-Sainte-Justine | New marker for the classification, diagnosis and treatment of scoliosis |
| EP3145513B1 (en) | 2014-05-19 | 2023-11-15 | Celgene Corporation | 3-(4-((4-(morpholinomethyl-benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione for the treatment of systemic lupus erythematosus |
| CN106310610A (zh) * | 2016-10-21 | 2017-01-11 | 上海交通大学医学院附属新华医院 | 一种脊柱侧凸特定运动疗法 |
| CN106841593B (zh) * | 2017-03-24 | 2018-08-17 | 北京致成生物医学科技有限公司 | Lacc1和fhl2基因在制备脊柱侧弯检测产品中的应用 |
| CN111638329B (zh) * | 2020-06-09 | 2021-06-01 | 南方医科大学 | 一种用于检测布鲁氏菌病elispot检测试剂盒及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| SE9101642D0 (sv) * | 1991-05-30 | 1991-05-30 | Kabi Pharmacia Ab | Phospholipids |
| EP0767378A1 (de) * | 1993-06-22 | 1997-04-09 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Diagnose und Analyse von Magenkarzinomen |
| EP0778776A1 (en) | 1994-08-30 | 1997-06-18 | Hyal Pharmaceutical Corporation | Hyaluronic acid and derivatives for modulation of cellular activity |
| US5858709A (en) * | 1996-10-15 | 1999-01-12 | Smithkline Beecham P.L.C. | Fibronectin binding protein B compounds |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US20020160970A1 (en) * | 1996-04-10 | 2002-10-31 | Gyula Hadlaczky | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| WO1998008379A1 (en) | 1996-08-27 | 1998-03-05 | Dana-Farber Cancer Institute | Methods for identifying modulators of cellular interactions mediated by osteopontin |
| US6150162A (en) * | 1998-12-17 | 2000-11-21 | Isis Pharmaceuticals Inc. | Antisense modulation of CD44 expression |
| JP2005517379A (ja) | 1999-01-18 | 2005-06-16 | オステオミーター・ビオテク・エー／エス | 遺伝的疾病素因 |
| IL145851A0 (en) * | 1999-04-15 | 2002-07-25 | Childrens Medical Center | Osteopontin-derived chemotactic and inhivitory agents and uses therefor |
| DE60131525T2 (de) | 2000-03-23 | 2008-09-25 | Glaxo Group Ltd., Greenford | Verfahren zum screening von inhibitoren für osteopontin |
| EP1431310A4 (en) * | 2001-09-25 | 2005-03-23 | Immuno Biological Lab Co Ltd | ANTI-OSTEOPONTIN RECOMBINANT ANTIBODY AND USE THEREOF |
| CA2373854A1 (en) | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
| WO2003081201A2 (en) * | 2002-03-21 | 2003-10-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Peripheral blood cell markers useful for diagnosing multiple sclerosis and methods and kits utilizing same |
| US20040110933A1 (en) * | 2002-09-13 | 2004-06-10 | Dyax Corporation | CD44-binding ligands |
| US20050282163A1 (en) * | 2003-02-03 | 2005-12-22 | Medstar Research Institute Washington Hospital Center | Polymorphisms in elastin, fibrillin and related genes as predisposing to restenosis and to a therosclerosis |
| US20090104620A1 (en) * | 2007-07-03 | 2009-04-23 | Axial Biotech, Inc. | Simplified Method of Determining Predisposition to Scoliosis |
-
2008
- 2008-03-31 CA CA2682114A patent/CA2682114C/en not_active Expired - Fee Related
- 2008-03-31 JP JP2010500039A patent/JP5426530B2/ja not_active Expired - Fee Related
- 2008-03-31 EP EP08733693.9A patent/EP2132568B1/en not_active Not-in-force
- 2008-03-31 CN CN200880017111.6A patent/CN101680887B/zh not_active Expired - Fee Related
- 2008-03-31 WO PCT/CA2008/000595 patent/WO2008119170A1/en not_active Ceased
- 2008-03-31 MX MX2009010400A patent/MX2009010400A/es active IP Right Grant
- 2008-03-31 US US12/594,181 patent/US20100075333A1/en not_active Abandoned
- 2008-03-31 KR KR1020097022732A patent/KR101436578B1/ko not_active Expired - Fee Related
- 2008-03-31 AU AU2008234374A patent/AU2008234374B2/en not_active Ceased
-
2009
- 2009-09-24 IL IL201186A patent/IL201186A/en active IP Right Grant
-
2013
- 2013-02-22 US US13/775,069 patent/US20130266966A1/en not_active Abandoned
-
2015
- 2015-07-23 US US14/807,450 patent/US10073101B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010522699A5 (enExample) | ||
| ES2403310T3 (es) | Antibiótico para su utilización en una infección local | |
| WO2010038974A3 (ko) | 이뮤노글로블린 에이 신증과 티지비엠 신증의 진단용 조성물 및 키트 | |
| Qian et al. | Increased IL-23 and IL-17 expression by peripheral blood cells of patients with primary biliary cirrhosis | |
| RU2014118584A (ru) | Композиции и способы лечения сердечной недостаточности | |
| WO2014059178A1 (en) | Differential expression of novel protein markers for the diagnosis and treatment of eosinophilic esophagitis | |
| JP2010516678A5 (enExample) | ||
| WO2009132058A3 (en) | Levels of bcma protein expression on b cells and use in diagnostic methods | |
| Takač et al. | Importance of interleukin 6 in pathogenesis of inflammatory bowel disease | |
| JP2012509477A5 (enExample) | ||
| RU2019106324A (ru) | Гистоны и/или proadm в качестве маркеров, свидетельствующих о неблагоприятном событии | |
| Stanescu et al. | Salivary biomarkers of inflammation in systemic lupus erythematosus | |
| Lien et al. | Associations among systemic blood pressure, microalbuminuria and albuminuria in dogs affected with pituitary-and adrenal-dependent hyperadrenocorticism | |
| Yuan et al. | High expression of interleukin-33/ST2 predicts the progression and poor prognosis in chronic hepatitis B patients with hepatic flare | |
| RU2008116567A (ru) | Биомаркеры | |
| Banaszak et al. | Endothelin-1 (ET-1), N-terminal fragment of pro-atrial natriuretic peptide (NTpro-ANP), and tumour necrosis factor alpha (TNF-α) in children with primary hypertension and hypertension of renal origin | |
| JP2012526543A5 (enExample) | ||
| Palatini et al. | Cystatin C as predictor of microalbuminuria in the early stage of hypertension | |
| Magnussen et al. | Safety and tolerability of an oral MMP-9 and-12 inhibitor, AZD1236, in patients with moderate-to-severe COPD: a randomised controlled 6-week trial | |
| Kim et al. | Clinical significance of anti-Saccharomyces cerevisiae antibody (ASCA) in Korean patients with Crohn's disease and its relationship to the disease clinical course | |
| Hanibuchi et al. | Clinical significance of fractional exhaled nitric oxide and periostin as potential markers to assess therapeutic efficacy in patients with cough variant asthma | |
| JP6934013B2 (ja) | 糖尿病性腎症の早期病態の特異的な診断を可能とする検査方法 | |
| Kikuchi et al. | Urinary and circulating levels of the anti-angiogenic isoform of vascular endothelial growth factor-A in patients with chronic kidney disease | |
| Kim et al. | Serum cytokines markers in toluene diisocyanate-induced asthma | |
| Swedin et al. | Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant |