JP2010522699A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010522699A5 JP2010522699A5 JP2010500039A JP2010500039A JP2010522699A5 JP 2010522699 A5 JP2010522699 A5 JP 2010522699A5 JP 2010500039 A JP2010500039 A JP 2010500039A JP 2010500039 A JP2010500039 A JP 2010500039A JP 2010522699 A5 JP2010522699 A5 JP 2010522699A5
- Authority
- JP
- Japan
- Prior art keywords
- scoliosis
- opn
- subject
- expression
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004264 Osteopontin Human genes 0.000 claims 35
- 108010081689 Osteopontin Proteins 0.000 claims 35
- 238000000034 method Methods 0.000 claims 34
- 206010039722 scoliosis Diseases 0.000 claims 28
- 239000000523 sample Substances 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 12
- 230000002265 prevention Effects 0.000 claims 9
- 238000002965 ELISA Methods 0.000 claims 4
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 4
- 102100032912 CD44 antigen Human genes 0.000 claims 3
- 208000022567 adolescent idiopathic scoliosis Diseases 0.000 claims 3
- 239000013060 biological fluid Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000005259 measurement Methods 0.000 claims 3
- 229940122231 Osteopontin inhibitor Drugs 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 238000003127 radioimmunoassay Methods 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000001964 muscle biopsy Methods 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 229910052711 selenium Inorganic materials 0.000 claims 1
- 239000011669 selenium Substances 0.000 claims 1
- 210000001138 tear Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90940807P | 2007-03-30 | 2007-03-30 | |
| US60/909,408 | 2007-03-30 | ||
| US2557108P | 2008-02-01 | 2008-02-01 | |
| US61/025,571 | 2008-02-01 | ||
| PCT/CA2008/000595 WO2008119170A1 (en) | 2007-03-30 | 2008-03-31 | Method of determining risk of scoliosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010522699A JP2010522699A (ja) | 2010-07-08 |
| JP2010522699A5 true JP2010522699A5 (enExample) | 2011-04-28 |
| JP5426530B2 JP5426530B2 (ja) | 2014-02-26 |
Family
ID=39807753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500039A Expired - Fee Related JP5426530B2 (ja) | 2007-03-30 | 2008-03-31 | 脊柱側弯症の危険性の決定方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20100075333A1 (enExample) |
| EP (1) | EP2132568B1 (enExample) |
| JP (1) | JP5426530B2 (enExample) |
| KR (1) | KR101436578B1 (enExample) |
| CN (1) | CN101680887B (enExample) |
| AU (1) | AU2008234374B2 (enExample) |
| CA (1) | CA2682114C (enExample) |
| IL (1) | IL201186A (enExample) |
| MX (1) | MX2009010400A (enExample) |
| WO (1) | WO2008119170A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2598875B1 (en) * | 2010-10-04 | 2016-12-07 | Chu Sainte-Justine | Biomechanical-based methods of diagnosing scoliosis |
| DE102012102338A1 (de) | 2012-03-20 | 2013-09-26 | Hauni Maschinenbau Ag | Messanordnung zum Messen von in Strangmaschinen der Tabak verarbeitenden Industrie hergestellten und geförderten Strängen |
| KR20210073616A (ko) | 2012-08-09 | 2021-06-18 | 셀진 코포레이션 | 면역-관련 및 염증성 질환의 치료 |
| US20150038511A1 (en) | 2012-08-09 | 2015-02-05 | Celgene Corporation | Treatment of immune-related and inflammatory diseases |
| KR20160020553A (ko) * | 2013-06-17 | 2016-02-23 | 슈 생-쥐스땡 | 특발성 척추측만증의 심각한 진행에 대한 새로운 마커, 그리고 척추측만 환자를 층화하고 척추측만증이 발달할 위험을 예측하기 위한 이들의 용도 |
| AU2014284075A1 (en) | 2013-06-17 | 2016-01-07 | Chu Sainte-Justine | Gi protein phosphorylation as marker for scoliosis and scoliosis progression, methods of increasing GiPCR signaling in scoliotic subjects |
| KR20160020554A (ko) * | 2013-06-17 | 2016-02-23 | 슈 생-쥐스땡 | 척추측만 개체의 세포에서 gipcr 신호전달을 증가시키는 방법 |
| WO2015032005A1 (en) * | 2013-09-09 | 2015-03-12 | Chu-Sainte-Justine | New marker for the classification, diagnosis and treatment of scoliosis |
| TWI745271B (zh) | 2014-05-19 | 2021-11-11 | 美商西建公司 | 全身紅斑性狼瘡之治療 |
| CN106310610A (zh) * | 2016-10-21 | 2017-01-11 | 上海交通大学医学院附属新华医院 | 一种脊柱侧凸特定运动疗法 |
| CN106841593B (zh) * | 2017-03-24 | 2018-08-17 | 北京致成生物医学科技有限公司 | Lacc1和fhl2基因在制备脊柱侧弯检测产品中的应用 |
| CN111638329B (zh) * | 2020-06-09 | 2021-06-01 | 南方医科大学 | 一种用于检测布鲁氏菌病elispot检测试剂盒及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| SE9101642D0 (sv) * | 1991-05-30 | 1991-05-30 | Kabi Pharmacia Ab | Phospholipids |
| CA2164728A1 (en) * | 1993-06-22 | 1995-01-05 | Helmut Ponta | Processes for diagnosing and analysing tumours |
| JPH10504828A (ja) | 1994-08-30 | 1998-05-12 | ハイアル ファーマスティカル コーポレイション | 細胞活性調整のためのヒアルロン酸およびその誘導体 |
| US5858709A (en) * | 1996-10-15 | 1999-01-12 | Smithkline Beecham P.L.C. | Fibronectin binding protein B compounds |
| US20020160970A1 (en) * | 1996-04-10 | 2002-10-31 | Gyula Hadlaczky | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| WO1998008379A1 (en) | 1996-08-27 | 1998-03-05 | Dana-Farber Cancer Institute | Methods for identifying modulators of cellular interactions mediated by osteopontin |
| US6150162A (en) * | 1998-12-17 | 2000-11-21 | Isis Pharmaceuticals Inc. | Antisense modulation of CD44 expression |
| JP2005517379A (ja) | 1999-01-18 | 2005-06-16 | オステオミーター・ビオテク・エー／エス | 遺伝的疾病素因 |
| IL145851A0 (en) * | 1999-04-15 | 2002-07-25 | Childrens Medical Center | Osteopontin-derived chemotactic and inhivitory agents and uses therefor |
| EP1269196B1 (en) | 2000-03-23 | 2007-11-21 | Glaxo Group Limited | Method of screening for inhibitors of osteopontin |
| RU2305111C2 (ru) * | 2001-09-25 | 2007-08-27 | Джуридикэл Фаундейшн Дзе Чемо-Серо-Терапьютик Рисерч Инститьют | Рекомбинантное антитело против остеопонтина и его применение |
| CA2373854A1 (en) | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
| EP1532268A4 (en) * | 2002-03-21 | 2006-07-05 | Yissum Res Dev Co | PERIPHERAL BLOOD CELL MARKERS SUITABLE FOR THE DIAGNOSIS OF MULTIPLE SCLEROSIS AND THESE USEFUL METHODS AND KITS |
| US20040110933A1 (en) * | 2002-09-13 | 2004-06-10 | Dyax Corporation | CD44-binding ligands |
| US20050282163A1 (en) * | 2003-02-03 | 2005-12-22 | Medstar Research Institute Washington Hospital Center | Polymorphisms in elastin, fibrillin and related genes as predisposing to restenosis and to a therosclerosis |
| US20090104620A1 (en) * | 2007-07-03 | 2009-04-23 | Axial Biotech, Inc. | Simplified Method of Determining Predisposition to Scoliosis |
-
2008
- 2008-03-31 JP JP2010500039A patent/JP5426530B2/ja not_active Expired - Fee Related
- 2008-03-31 MX MX2009010400A patent/MX2009010400A/es active IP Right Grant
- 2008-03-31 WO PCT/CA2008/000595 patent/WO2008119170A1/en not_active Ceased
- 2008-03-31 US US12/594,181 patent/US20100075333A1/en not_active Abandoned
- 2008-03-31 AU AU2008234374A patent/AU2008234374B2/en not_active Ceased
- 2008-03-31 KR KR1020097022732A patent/KR101436578B1/ko not_active Expired - Fee Related
- 2008-03-31 EP EP08733693.9A patent/EP2132568B1/en not_active Not-in-force
- 2008-03-31 CA CA2682114A patent/CA2682114C/en not_active Expired - Fee Related
- 2008-03-31 CN CN200880017111.6A patent/CN101680887B/zh not_active Expired - Fee Related
-
2009
- 2009-09-24 IL IL201186A patent/IL201186A/en active IP Right Grant
-
2013
- 2013-02-22 US US13/775,069 patent/US20130266966A1/en not_active Abandoned
-
2015
- 2015-07-23 US US14/807,450 patent/US10073101B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Balzar et al. | Increased TGF-β2 in severe asthma with eosinophilia | |
| ES2897419T3 (es) | Procedimientos de predicción del riesgo de un resultado clínico adverso | |
| ES2403310T3 (es) | Antibiótico para su utilización en una infección local | |
| ES2717900T3 (es) | Método para la detección temprana de enfermedad y lesión renal | |
| Feld et al. | Endpoints of therapy in chronic hepatitis B | |
| RU2014118584A (ru) | Композиции и способы лечения сердечной недостаточности | |
| Cho et al. | Endometrial osteopontin mRNA expression and plasma osteopontin levels are increased in patients with endometriosis | |
| WO2014059178A1 (en) | Differential expression of novel protein markers for the diagnosis and treatment of eosinophilic esophagitis | |
| JP2010516678A5 (enExample) | ||
| JP2006521565A5 (enExample) | ||
| JP2013534313A (ja) | 腸の炎症状態の生物学的マーカーとしてのｈｍｇｂ１の使用、糞便サンプル中のｈｍｇｂ１を検出するための非侵襲法およびそのキット | |
| WO2009132058A3 (en) | Levels of bcma protein expression on b cells and use in diagnostic methods | |
| JP2012509477A5 (enExample) | ||
| US20080058360A1 (en) | Soluble CD40L (CD 154) as a prognostic marker of atherosclerotic diseases | |
| Stanescu et al. | Salivary biomarkers of inflammation in systemic lupus erythematosus | |
| Lien et al. | Associations among systemic blood pressure, microalbuminuria and albuminuria in dogs affected with pituitary-and adrenal-dependent hyperadrenocorticism | |
| RU2008116567A (ru) | Биомаркеры | |
| Banaszak et al. | Endothelin-1 (ET-1), N-terminal fragment of pro-atrial natriuretic peptide (NTpro-ANP), and tumour necrosis factor alpha (TNF-α) in children with primary hypertension and hypertension of renal origin | |
| JP2012526543A5 (enExample) | ||
| Li et al. | Thyrotropin receptor antibody: A novel risk indicator for pregnancy loss | |
| Magnussen et al. | Safety and tolerability of an oral MMP-9 and-12 inhibitor, AZD1236, in patients with moderate-to-severe COPD: a randomised controlled 6-week trial | |
| Hanibuchi et al. | Clinical significance of fractional exhaled nitric oxide and periostin as potential markers to assess therapeutic efficacy in patients with cough variant asthma | |
| Strak et al. | A study of lichen planus and its association with hepatitis C infection | |
| Kikuchi et al. | Urinary and circulating levels of the anti-angiogenic isoform of vascular endothelial growth factor-A in patients with chronic kidney disease | |
| Kim et al. | Serum cytokines markers in toluene diisocyanate-induced asthma |